Table of Contents

Articles

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  Molecular Properties of Amphotericin B Membrane Channel: A Molecular Dynamics Simulation

  Maciej Baginski, Haluk Resat and J. Andrew McCammon

  Molecular Pharmacology October 1997, 52 (4) 560-570; DOI: https://doi.org/10.1124/mol.52.4.560
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  Steroid-Independent Translocation of the Glucocorticoid Receptor by the Antidepressant Desipramine

  Carmine M. Pariante, Bradley D. Pearce, Tracy L. Pisell, Michael J. Owens and Andrew H. Miller

  Molecular Pharmacology October 1997, 52 (4) 571-581; DOI: https://doi.org/10.1124/mol.52.4.571
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  Identification and Characterization of a Novel Endothelin Receptor That Binds Both ET_A- and ET_B-Selective Ligands

  Ponnal Nambi, Mark Pullen, Jamie Kincaid, Parvathi Nuthulaganti, Nambi Aiyar, David P. Brooks, Miklos Gellai and Chandrika Kumar

  Molecular Pharmacology October 1997, 52 (4) 582-589; DOI: https://doi.org/10.1124/mol.52.4.582
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  Aryl Hydrocarbon Receptor-Dependent Induction of Cyp1a1 by Bilirubin in Mouse Hepatoma Hepa 1c1c7 Cells

  Christopher J. Sinal and John R. Bend

  Molecular Pharmacology October 1997, 52 (4) 590-599; DOI: https://doi.org/10.1124/mol.52.4.590
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  Prevention of Fluorodeoxyuridine-Induced Cytotoxicity and DNA Damage in HT29 Colon Carcinoma Cells by Conditional Expression of Wild-Type p53 Phenotype

  Leslie A. Parsels, Richard C. Zellars, Tania L. Loney, Joshua D. Parsels, Michael F. Clarke, Audrea K. Merchant, Theodore S. Lawrence and Jonathan Maybaum

  Molecular Pharmacology October 1997, 52 (4) 600-605; DOI: https://doi.org/10.1124/mol.52.4.600
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  Inhalational Anesthetics Up-Regulate Constitutive and Lipopolysaccharide-Induced Inducible Nitric Oxide Synthase Expression and Activity

  Zhiyi Zuo and Roger A. Johns

  Molecular Pharmacology October 1997, 52 (4) 606-612; DOI: https://doi.org/10.1124/mol.52.4.606
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  The Microtubule-Stabilizing Agent Discodermolide Competitively Inhibits the Binding of Paclitaxel (Taxol) to Tubulin Polymers, Enhances Tubulin Nucleation Reactions More Potently than Paclitaxel, and Inhibits the Growth of Paclitaxel-Resistant Cells

  Richard J. Kowalski, Paraskevi Giannakakou, Sarath P. Gunasekera, Ross E. Longley, Billy W. Day and Ernest Hamel

  Molecular Pharmacology October 1997, 52 (4) 613-622; DOI: https://doi.org/10.1124/mol.52.4.613
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  5-Hydroxytryptamine_1A and 5-Hydroxytryptamine_1B Receptors Stimulate [³⁵S]Guanosine-5′-O-(3-thio)triphosphate Binding to Rodent Brain Sections as Visualized by In Vitro Autoradiography

  Christian Waeber and Michael A. Moskowitz

  Molecular Pharmacology October 1997, 52 (4) 623-631; DOI: https://doi.org/10.1124/mol.52.4.623
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  Induction of Multiple Effects on Adenylyl Cyclase Regulation by Chronic Activation of the Human A₃ Adenosine Receptor

  Timothy M. Palmer, Carol A. Harris, James Coote and Gary L. Stiles

  Molecular Pharmacology October 1997, 52 (4) 632-640; DOI: https://doi.org/10.1124/mol.52.4.632
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  Increased Activity and Expression of Tyrosine Hydroxylase in the Rat Substantia Nigra after Chronic Treatment with Nomifensine

  José A. Rodríguez-Gómez, Marina Romero-Ramos, María L. Vizuete, José L. Venero, Josefina Cano and Alberto Machado

  Molecular Pharmacology October 1997, 52 (4) 641-647; DOI: https://doi.org/10.1124/mol.52.4.641
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  Menadione Cytotoxicity to Hep G2 Cells and Protection by Activation of Nuclear Factor-κB

  Qi Chen and Arthur I. Cederbaum

  Molecular Pharmacology October 1997, 52 (4) 648-657; DOI: https://doi.org/10.1124/mol.52.4.648
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  Identification of Yeast DNA Topoisomerase II Mutants Resistant to the Antitumor Drug Doxorubicin: Implications for the Mechanisms of Doxorubicin Action and Cytotoxicity

  Sandhiya Patel, Antje U. Sprung, Beatrice A. Keller, Victoria J. Heaton and L. Mark Fisher

  Molecular Pharmacology October 1997, 52 (4) 658-666; DOI: https://doi.org/10.1124/mol.52.4.658
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  2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Activation of a Protein Tyrosine Kinase, pp60^src, in Murine Hepatic Cytosol Using a Cell-Free System

  Alan Blankenship and Fumio Matsumura

  Molecular Pharmacology October 1997, 52 (4) 667-675; DOI: https://doi.org/10.1124/mol.52.4.667
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  Residues at Positions 206 and 209 of the α1 Subunit of γ-Aminobutyric Acid_A Receptors Influence Affinities for Benzodiazepine Binding Site Ligands

  Andreas Buhr, Martin T. Schaerer, Roland Baur and Erwin Sigel

  Molecular Pharmacology October 1997, 52 (4) 676-682; DOI: https://doi.org/10.1124/mol.52.4.676
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  Differential A₁ Adenosine Receptor Reserve for Two Actions of Adenosine on Guinea Pig Atrial Myocytes

  Miduturu Srinivas, John C. Shryock, Donn M. Dennis, Stephen P. Baker and Luiz Belardinelli

  Molecular Pharmacology October 1997, 52 (4) 683-691; DOI: https://doi.org/10.1124/mol.52.4.683
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  Lipopolysaccharide and the Glycoside Ring of Staurosporine Induce CD14 Expression on Bone Marrow Granulocytes by Different Mechanisms

  Thierry Pedron, Robert Girard, Kengo Inoue, Daniel Charon and Richard Chaby

  Molecular Pharmacology October 1997, 52 (4) 692-700; DOI: https://doi.org/10.1124/mol.52.4.692
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  Block and Modulation ofN-Methyl-d-Aspartate Receptors by Polyamines and Protons: Role of Amino Acid Residues in the Transmembrane and Pore-Forming Regions of NR1 and NR2 Subunits

  Keiko Kashiwagi, Albert J. Pahk, Takashi Masuko, Kazuei Igarashi and Keith Williams

  Molecular Pharmacology October 1997, 52 (4) 701-713; DOI: https://doi.org/10.1124/mol.52.4.701
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  The Role of α1 and α6 Subtype Amino-Terminal Domains in Allosteric Regulation of γ-Aminobutyric Acid_a Receptors

  Janet L. Fisher, Jie Zhang and Robert L. Macdonald

  Molecular Pharmacology October 1997, 52 (4) 714-724; DOI: https://doi.org/10.1124/mol.52.4.714
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  Effects of Protein Phosphatase and Kinase Inhibitors on Ca²⁺ and Cl⁻ Currents in Guinea Pig Ventricular Myocytes

  Yoshiyuki Hirayama and H. Criss Hartzell

  Molecular Pharmacology October 1997, 52 (4) 725-734; DOI: https://doi.org/10.1124/mol.52.4.725
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  Transfer of the High Affinity Dihydropyridine Sensitivity from L-Type To Non-L-Type Calcium Channel

  Hiroyuki Ito, Norbert Klugbauer and Franz Hofmann

  Molecular Pharmacology October 1997, 52 (4) 735-740; DOI: https://doi.org/10.1124/mol.52.4.735
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  Structural Analogues ofd-myo-Inositol-1,4,5-trisphosphate and Adenophostin A: Recognition by Cerebellar and Platelet Inositol-1,4,5-trisphosphate Receptors

  C. T. Murphy, A. M. Riley, C. J. Lindley, D. J. Jenkins, J. Westwick and B. V. L. Potter

  Molecular Pharmacology October 1997, 52 (4) 741-748; DOI: https://doi.org/10.1124/mol.52.4.741
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  21-Hydroxy-6,19-oxidoprogesterone: A Novel Synthetic Steroid with Specific Antiglucocorticoid Properties in the Rat

  G. P. Vicent, M. C. Monteserín, A. S. Veleiro, G. Burton, C. P. Lantos and M. D. Galigniana

  Molecular Pharmacology October 1997, 52 (4) 749-753; DOI: https://doi.org/10.1124/mol.52.4.749