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Molecular Pharmacology

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Table of Contents

December 01, 1997; Volume 52,Issue 6

Accelerated Communications

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    Leukocyte Activation Induces Aryl Hydrocarbon Receptor Up-Regulation, DNA Binding, and Increased Cyp1a1Expression in the Absence of Exogenous Ligand
    Robert B. Crawford, Michael P. Holsapple and Norbert E. Kaminski
    Molecular Pharmacology December 1997, 52 (6) 921-927; DOI: https://doi.org/10.1124/mol.52.6.921
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    Molecular Cloning and Expression of an Avian G Protein-Coupled P2Y Receptor
    José L. Boyer, Gary L. Waldo and T. Kendall Harden
    Molecular Pharmacology December 1997, 52 (6) 928-934; DOI: https://doi.org/10.1124/mol.52.6.928

Articles

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    Coordinate Regulation of Stress- and Mitogen-Activated Protein Kinases in the Apoptotic Actions of Ceramide and Sphingosine
    W. David Jarvis, Frank A. Fornari, Kelly L. Auer, Alex J. Freemerman, Eva Szabo, Michael J. Birrer, Charlene R. Johnson, Suzanne E. Barbour, Paul Dent and Steven Grant
    Molecular Pharmacology December 1997, 52 (6) 935-947; DOI: https://doi.org/10.1124/mol.52.6.935
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    Characterization of a Novel Bisacridone and Comparison with PSC 833 as a Potent and Poorly Reversible Modulator of P-Glycoprotein
    Julie K. Horton, Kuntebommanahalli N. Thimmaiah, Guillermo A. Altenberg, Ariel F. Castro, Glen S. Germain, G. Krishne Gowda and Peter J. Houghton
    Molecular Pharmacology December 1997, 52 (6) 948-957; DOI: https://doi.org/10.1124/mol.52.6.948
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    Characterization of a Human GlutathioneS-Transferase μ Cluster Containing a DuplicatedGSTM1 Gene that Causes Ultrarapid Enzyme Activity
    Roman A. McLellan, Mikael Oscarson, Anna-Karin Alexandrie, Janeric Seidegård, David A. Price Evans, Agneta Rannug and Magnus Ingelman-Sundberg
    Molecular Pharmacology December 1997, 52 (6) 958-965; DOI: https://doi.org/10.1124/mol.52.6.958
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    Regulation of m2 Muscarinic Receptor Gene Expression by Platelet-Derived Growth Factor: Involvement of Extracellular Signal-Regulated Protein Kinases in the Down-Regulation Process
    Jonathan Rousell, El-Bdaoui Haddad, Mark A. Lindsay and Peter J. Barnes
    Molecular Pharmacology December 1997, 52 (6) 966-973; DOI: https://doi.org/10.1124/mol.52.6.966
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    Identification of Benzo[a]pyrene-InducibleCis-Acting Elements Within c-Ha-rasTranscriptional Regulatory Sequences
    C. M. Bral and K. S. Ramos
    Molecular Pharmacology December 1997, 52 (6) 974-982; DOI: https://doi.org/10.1124/mol.52.6.974
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    Naloxone Activation of μ-Opioid Receptors Mutated at a Histidine Residue Lining the Opioid Binding Cavity
    Charles E. Spivak, Carol L. Beglan, Brian K. Seidleck, Laura D. Hirshbein, Carrie J. Blaschak, George R. Uhl and Christopher K. Surratt
    Molecular Pharmacology December 1997, 52 (6) 983-992; DOI: https://doi.org/10.1124/mol.52.6.983
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    Enhanced Stimulatory Adenylyl Cyclase Signaling during Opioid Dependence Is Associated with a Reduction in Palmitoylated Gsα
    Hermann Ammer and Rüdiger Schulz
    Molecular Pharmacology December 1997, 52 (6) 993-999; DOI: https://doi.org/10.1124/mol.52.6.993
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    Agents that Down-Regulate or Inhibit Protein Kinase C Circumvent Resistance to 1-β-D-Arabinofuranosylcytosine-Induced Apoptosis in Human Leukemia Cells that Overexpress Bcl-2
    Shujie Wang, Julie A. Vrana, Tina M. Bartimole, Alex J. Freemerman, W. David Jarvis, Lora B. Kramer, Geoffrey Krystal, Paul Dent and Steven Grant
    Molecular Pharmacology December 1997, 52 (6) 1000-1009; DOI: https://doi.org/10.1124/mol.52.6.1000
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    Proximal Nephron Na+/H+ Exchange Is Regulated by α1A- and α1B-Adrenergic Receptor Subtypes
    Fengming Liu, Teresa Nesbitt, Marc K. Drezner, Peter A. Friedman and Frank A. Gesek
    Molecular Pharmacology December 1997, 52 (6) 1010-1018; DOI: https://doi.org/10.1124/mol.52.6.1010
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    Both the Cyclic AMP Response Element and the Activator Protein 2 Binding Site Mediate Basal and Cyclic AMP-Induced Transcription from the Dominant Promoter of the Rat α1B-Adrenergic Receptor Gene in DDT1MF-2 Cells
    Bin Gao, Jianping Chen, Carl Johnson and George Kunos
    Molecular Pharmacology December 1997, 52 (6) 1019-1026; DOI: https://doi.org/10.1124/mol.52.6.1019
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    Neuropeptide Y Inhibits Chromaffin Cell Nicotinic Receptor-Stimulated Tyrosine Hydroxylase Activity through a Receptor-Linked G Protein-Mediated Process
    Jialin Zheng, Peijin Zhang and Terry D. Hexum
    Molecular Pharmacology December 1997, 52 (6) 1027-1033; DOI: https://doi.org/10.1124/mol.52.6.1027
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    A Combination of Mutations in the CYP2D6*17(CYP2D6Z) Allele Causes Alterations in Enzyme Function
    Mikael Oscarson, Mats Hidestrand, Inger Johansson and Magnus Ingelman-Sundberg
    Molecular Pharmacology December 1997, 52 (6) 1034-1040; DOI: https://doi.org/10.1124/mol.52.6.1034
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    Potent Inhibitors of Human Immunodeficiency Virus Type 1 Integrase: Identification of a Novel Four-Point Pharmacophore and Tetracyclines as Novel Inhibitors
    Nouri Neamati, Huixiao Hong, Sanjay Sunder, George W. A. Milne and Yves Pommier
    Molecular Pharmacology December 1997, 52 (6) 1041-1055; DOI: https://doi.org/10.1124/mol.52.6.1041
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    Antisense Inhibition of 5-Hydroxytryptamine2aReceptor Induces an Antidepressant-Like Effect in Mice
    Etienne Sibille, Zoltan Sarnyai, Daniel Benjamin, Judit Gal, Harriet Baker and Miklos Toth
    Molecular Pharmacology December 1997, 52 (6) 1056-1063; DOI: https://doi.org/10.1124/mol.52.6.1056
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    Role of Gαq or Gαo Proteins in α1-Adrenoceptor Subtype-Mediated Responses in Fischer 344 Rat Aorta
    Hakan Gurdal, Tammy M. Seasholtz, Hoau-Yan Wang, R. Dale Brown, Mark D. Johnson and Eitan Friedman
    Molecular Pharmacology December 1997, 52 (6) 1064-1070; DOI: https://doi.org/10.1124/mol.52.6.1064
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    Distribution of mRNA Encoding Three α2-Adrenergic Receptor Subtypes in the Developing Mouse Embryo Suggests a Role for the α2A Subtype in Apoptosis
    Ren-Xue Wang and Lee E. Limbird
    Molecular Pharmacology December 1997, 52 (6) 1071-1080; DOI: https://doi.org/10.1124/mol.52.6.1071
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    In Vivo Production of Nitric Oxide in Rats after Administration of Hydroxyurea
    Jinjie Jiang, Sandra J. Jordan, David P. Barr, Michael R. Gunther, Hiroshi Maeda and Ronald P. Mason
    Molecular Pharmacology December 1997, 52 (6) 1081-1086; DOI: https://doi.org/10.1124/mol.52.6.1081
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    Site-Directed Mutagenesis on the m2 Muscarinic Acetylcholine Receptor: The Significance of Tyr403 in the Binding of Agonists and Functional Coupling
    Walter K. Vogel, David M. Sheehan and Michael I. Schimerlik
    Molecular Pharmacology December 1997, 52 (6) 1087-1094; DOI: https://doi.org/10.1124/mol.52.6.1087
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    Voltage-Dependent Inhibition of N- and P-Type Calcium Channels by the Peptide Toxin ω-Grammotoxin-SIA
    Stefan I. McDonough, Richard A. Lampe, Richard A. Keith and Bruce P. Bean
    Molecular Pharmacology December 1997, 52 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.52.6.1095
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    Functional Deactivation of the Major Neuronal Nicotinic Receptor Caused by Nicotine and a Protein Kinase C-Dependent Mechanism
    Helge Eilers, Eric Schaeffer, Philip E. Bickler and John R. Forsayeth
    Molecular Pharmacology December 1997, 52 (6) 1105-1112; DOI: https://doi.org/10.1124/mol.52.6.1105
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    Distinct Sites for Inverse Modulation ofN-Methyl-d-Aspartate Receptors by Sulfated Steroids
    Mijeong Park-Chung, Fong-Sen Wu, Robert H. Purdy, Andrew A. Malayev, Terrell T. Gibbs and David H. Farb
    Molecular Pharmacology December 1997, 52 (6) 1113-1123; DOI: https://doi.org/10.1124/mol.52.6.1113
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    Ca2+ Feedback on “Quantal” Ca2+Release Involving Ryanodine Receptors
    Christine Dettbarn and Philip Palade
    Molecular Pharmacology December 1997, 52 (6) 1124-1130; DOI: https://doi.org/10.1124/mol.52.6.1124
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    KvLQT1 Potassium Channel but Not IsK Is the Molecular Target fortrans-6-Cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethyl-chromane
    Gildas Loussouarn, Flavien Charpentier, Raha Mohammad-Panah, Karl Kunzelmann, Isabelle Baró and Denis Escande
    Molecular Pharmacology December 1997, 52 (6) 1131-1136; DOI: https://doi.org/10.1124/mol.52.6.1131
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    Constitutive Activity of a Chimeric D2/D1Dopamine Receptor
    Laura B. Kozell and Kim A. Neve
    Molecular Pharmacology December 1997, 52 (6) 1137-1149; DOI: https://doi.org/10.1124/mol.52.6.1137
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    Differences in Agonist/Antagonist Binding Affinity and Receptor Transduction Using Recombinant Human γ-Aminobutyric Acid Type A Receptors
    Bjarke Ebert, Sally A. Thompson, Koralia Saounatsou, Ruth McKernan, Povl Krogsgaard-Larsen and Keith A. Wafford
    Molecular Pharmacology December 1997, 52 (6) 1150-1156; DOI: https://doi.org/10.1124/mol.52.6.1150
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    S -Adenosylhomocysteine Hydrolase Inhibitors Interfere with the Replication of Human Immunodeficiency Virus Type 1 through Inhibition of the LTR Transactivation
    Dirk Daelemans, Jose A. Esté, Myriam Witvrouw, Christophe Pannecouque, Heidi Jonckheere, Stefano Aquaro, Carlo-Federico Perno, Erik De Clercq and Anne-Mieke Vandamme
    Molecular Pharmacology December 1997, 52 (6) 1157-1163; DOI: https://doi.org/10.1124/mol.52.6.1157
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    Expression Cloning and Receptor Pharmacology of Human Calcitonin Receptors from MCF-7 Cells and Their Relationship to Amylin Receptors
    Wen-Ji Chen, Susan Armour, James Way, Grace Chen, Chris Watson, Paul Irving, Jeff Cobb, Sue Kadwell, Kevin Beaumont, Tom Rimele and Terry Kenakin
    Molecular Pharmacology December 1997, 52 (6) 1164-1175; DOI: https://doi.org/10.1124/mol.52.6.1164
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Molecular Pharmacology: 52 (6)
Molecular Pharmacology
Vol. 52, Issue 6
1 Dec 1997
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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