Table of Contents

Articles

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  Molecular Cloning, Functional Expression, and Pharmacological Characterization of 5-Hydroxytryptamine₃ Receptor cDNA and Its Splice Variants from Guinea Pig

  Silke Lankiewicz, Nicole Lobitz, Christian H. R. Wetzel, Rainer Rupprecht, Günter Gisselmann and Hanns Hatt

  Molecular Pharmacology February 1998, 53 (2) 202-212; DOI: https://doi.org/10.1124/mol.53.2.202
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  S16020–2, a New Highly Cytotoxic Antitumor Olivacine Derivative: DNA Interaction and DNA Topoisomerase II Inhibition

  Sandrine Le Mée, Alain Pierré, Judith Markovits, Ghanem Atassi, Alain Jacquemin-Sablon and Jean-Marie Saucier

  Molecular Pharmacology February 1998, 53 (2) 213-220; DOI: https://doi.org/10.1124/mol.53.2.213
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  Stimulation of Phospholipase D via α₁-Adrenergic Receptors in Madin-Darby Canine Kidney Cells is Independent of PKCα and -ε Activation

  María A. Balboa and Paul A. Insel

  Molecular Pharmacology February 1998, 53 (2) 221-227; DOI: https://doi.org/10.1124/mol.53.2.221
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  In Vitro Binding Characteristics of a New Selective Group II Metabotropic Glutamate Receptor Radioligand, [³H]LY354740, in Rat Brain

  Hervé Schaffhauser, J. Grayson Richards, Jayne Cartmell, Sylvie Chaboz, John A. Kemp, Agnès Klingelschmidt, Jürg Messer, Heinz Stadler, Thomas Woltering and Vincent Mutel

  Molecular Pharmacology February 1998, 53 (2) 228-233; DOI: https://doi.org/10.1124/mol.53.2.228
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  Localization of Leptin Binding Domain in the Leptin Receptor

  Tung Ming Fong, Ruey-Ruey C. Huang, Michael R. Tota, Cheri Mao, Tim Smith, Jeff Varnerin, Vladimir V. Karpitskiy, James E. Krause and Lex H. T. Van der Ploeg

  Molecular Pharmacology February 1998, 53 (2) 234-240; DOI: https://doi.org/10.1124/mol.53.2.234
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  Mining the National Cancer Institute Anticancer Drug Discovery Database: Cluster Analysis of Ellipticine Analogs with p53-Inverse and Central Nervous System-Selective Patterns of Activity

  Leming M. Shi, Timothy G. Myers, Yi Fan, Patrick M. O’Connor, Kenneth D. Paull, Stephen H. Friend and John N. Weinstein

  Molecular Pharmacology February 1998, 53 (2) 241-251; DOI: https://doi.org/10.1124/mol.53.2.241
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  Modulation of Fluorouracil Cytotoxicity by Interferon-α and -γ

  A.-S.A. Ismail, C. J. Van Groeningen, A. Hardcastle, Q.-F. Ren, G. W. Aherne, F. Geoffroy, C. J. Allegra and J. L. Grem.

  Molecular Pharmacology February 1998, 53 (2) 252-261; DOI: https://doi.org/10.1124/mol.53.2.252
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  Liver Uptake of Phosphodiester Oligodeoxynucleotides Is Mediated by Scavenger Receptors

  Erik A. L. Biessen, Helene Vietsch, Johan Kuiper, Martin K. Bijsterbosch and Theo J. C. van Berkel

  Molecular Pharmacology February 1998, 53 (2) 262-269; DOI: https://doi.org/10.1124/mol.53.2.262
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  Substrate Specificity of Human Recombinant Mitochondrial Deoxyguanosine Kinase with Cytostatic and Antiviral Purine and Pyrimidine Analogs

  Anita Herrström Sjöberg, Liya Wang and Staffan Eriksson

  Molecular Pharmacology February 1998, 53 (2) 270-273; DOI: https://doi.org/10.1124/mol.53.2.270
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  Expression and Characterization of a Novel Thyroid Hormone-Sulfating Form of Cytosolic Sulfotransferase from Human Liver

  Jin Wang, Josie L. Falany and Charles N. Falany

  Molecular Pharmacology February 1998, 53 (2) 274-282; DOI: https://doi.org/10.1124/mol.53.2.274
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  Ivermectin: A Positive Allosteric Effector of the α7 Neuronal Nicotinic Acetylcholine Receptor

  Ryoko M. Krause, Bruno Buisson, Sonia Bertrand, Pierre-Jean Corringer, Jean-Luc Galzi, Jean-Pierre Changeux and Daniel Bertrand

  Molecular Pharmacology February 1998, 53 (2) 283-294; DOI: https://doi.org/10.1124/mol.53.2.283
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  Molecular Dissection of Benzodiazepine Binding and Allosteric Coupling Using Chimeric γ-Aminobutyric Acid_A Receptor Subunits

  Andrew J. Boileau, Amy M. Kucken, Amy R. Evers and Cynthia Czajkowski

  Molecular Pharmacology February 1998, 53 (2) 295-303; DOI: https://doi.org/10.1124/mol.53.2.295
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  M₂ Receptor Binding of the Selective Antagonist AF-DX 384: Possible Involvement of the Common Allosteric Site

  C. Tränkle, I. Andresen, G. Lambrecht and K. Mohr

  Molecular Pharmacology February 1998, 53 (2) 304-312; DOI: https://doi.org/10.1124/mol.53.2.304
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  Lipoxygenase Metabolites as Mediators of UTP-Induced Intracellular Acidification in Mouse RAW 264.7 Macrophages

  Wan-Wan Lin, Sheng-Ho Chang and Mei-Lin Wu

  Molecular Pharmacology February 1998, 53 (2) 313-321; DOI: https://doi.org/10.1124/mol.53.2.313
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  β-Lactams SB 212047 and SB 216754 Are Irreversible, Time-Dependent Inhibitors of Coenzyme A-Independent Transacylase

  James D. Winkler, Chiu-Mei Sung, Marie Chabot-Flecher, Don E. Griswold, Lisa A. Marshall, Floyd H. Chilton, William Bondinell and Ruth J. Mayer

  Molecular Pharmacology February 1998, 53 (2) 322-329; DOI: https://doi.org/10.1124/mol.53.2.322
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  Effects of Almitrine Bismesylate on the Ionic Currents of Chemoreceptor Cells from the Carotid Body

  J. R. López-López, M. T. Pérez-García, E. Canet and C. Gonzalez

  Molecular Pharmacology February 1998, 53 (2) 330-339; DOI: https://doi.org/10.1124/mol.53.2.330
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  Human Immunodeficiency Virus Glycoprotein gp120 as the Primary Target for the Antiviral Action of AR177 (Zintevir)

  José A. Esté, Cecilia Cabrera, Dominique Schols, Peter Cherepanov, Arantxa Gutierrez, Myriam Witvrouw, Christophe Pannecouque, Zeger Debyser, Robert F. Rando, Bonaventura Clotet, Jan Desmyter and Erik De Clercq

  Molecular Pharmacology February 1998, 53 (2) 340-345; DOI: https://doi.org/10.1124/mol.53.2.340