The Ortho-Quinone Metabolite of the Anticancer  Drug Etoposide (VP-16) Is a Potent Inhibitor of the Topoisomerase II/DNA Cleavable Complex

Tsvetan G. Gantchev; Darel J. Hunting

doi:10.1124/mol.53.3.422

Research ArticleArticle

The Ortho-Quinone Metabolite of the Anticancer Drug Etoposide (VP-16) Is a Potent Inhibitor of the Topoisomerase II/DNA Cleavable Complex

Tsvetan G. Gantchev and Darel J. Hunting

Molecular Pharmacology March 1998, 53 (3) 422-428; DOI: https://doi.org/10.1124/mol.53.3.422

Tsvetan G. Gantchev

Medical Research Council Group in the Radiation Sciences, Department of Nuclear Medicine and Radiobiology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada

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Darel J. Hunting

Medical Research Council Group in the Radiation Sciences, Department of Nuclear Medicine and Radiobiology, Faculty of Medicine, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada

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Molecular Pharmacology

Vol. 53, Issue 3

1 Mar 1998

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Research ArticleArticle

The Ortho-Quinone Metabolite of the Anticancer Drug Etoposide (VP-16) Is a Potent Inhibitor of the Topoisomerase II/DNA Cleavable Complex

Tsvetan G. Gantchev and Darel J. Hunting

Molecular Pharmacology March 1, 1998, 53 (3) 422-428; DOI: https://doi.org/10.1124/mol.53.3.422

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Research ArticleArticle

The Ortho-Quinone Metabolite of the Anticancer Drug Etoposide (VP-16) Is a Potent Inhibitor of the Topoisomerase II/DNA Cleavable Complex

Tsvetan G. Gantchev and Darel J. Hunting

Molecular Pharmacology March 1, 1998, 53 (3) 422-428; DOI: https://doi.org/10.1124/mol.53.3.422

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