Table of Contents

Articles

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  Involvement of c-Jun NH₂-Terminal Kinase Activation and c-Jun in the Induction of Apoptosis by the Ether Phospholipid 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine

  Consuelo Gajate, Antonio Santos-Beneit, Manuel Modolell and Faustino Mollinedo

  Molecular Pharmacology April 1998, 53 (4) 602-612; DOI: https://doi.org/10.1124/mol.53.4.602
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  A G Protein βγ Dimer-Mediated Pathway Contributes to Mitogen-Activated Protein Kinase Activation by Thyrotropin-Releasing Hormone Receptors in Transfected COS-7 Cells

  Teresa Palomero, Francisco Barros, Donato del Camino, Cristina G. Viloria and Pilar de la Peña

  Molecular Pharmacology April 1998, 53 (4) 613-622; DOI: https://doi.org/10.1124/mol.53.4.613
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  Aryl Hydrocarbon Receptor-Dependent Suppression by 2,3,7,8-Tetrachlorodibenzo-p-dioxin of IgM Secretion in Activated B Cells

  Courtney E. W. Sulentic, Michael P. Holsapple and Norbert E. Kaminski

  Molecular Pharmacology April 1998, 53 (4) 623-629; DOI: https://doi.org/10.1124/mol.53.4.623
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  Activation of Protein Kinase Cα and/or ε Enhances Transcription of the Human Endothelial Nitric Oxide Synthase Gene

  Huige Li, Silke A. Oehrlein, Thomas Wallerath, Irmgard Ihrig-Biedert, Paulus Wohlfart, Thomas Ulshöfer, Timm Jessen, Thomas Herget, Ulrich Förstermann and Hartmut Kleinert

  Molecular Pharmacology April 1998, 53 (4) 630-637; DOI: https://doi.org/10.1124/mol.53.4.630
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  Cytotoxicity and Apoptosis Produced by Cytochrome P450 2E1 in Hep G2 Cells

  Qi Chen and Arthur I. Cederbaum

  Molecular Pharmacology April 1998, 53 (4) 638-648; DOI: https://doi.org/10.1124/mol.53.4.638
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  Altered Brain Serotonin Homeostasis and Locomotor Insensitivity to 3,4-Methylenedioxymethamphetamine (“Ecstasy”) in Serotonin Transporter-Deficient Mice

  Dietmar Bengel, Dennis L. Murphy, Anne M. Andrews, Christine H. Wichems, Douglas Feltner, Armin Heils, Rainald Mössner, Heiner Westphal and Klaus-Peter Lesch

  Molecular Pharmacology April 1998, 53 (4) 649-655; DOI: https://doi.org/10.1124/mol.53.4.649
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  Differences Among Type I, II, and III Inositol-1,4,5-Trisphosphate Receptors in Ligand-Binding Affinity Influence the Sensitivity of Calcium Stores to Inositol-1,4,5-Trisphosphate

  Richard J. H. Wojcikiewicz and Su Ge Luo

  Molecular Pharmacology April 1998, 53 (4) 656-662; DOI: https://doi.org/10.1124/mol.53.4.656
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  Oxidative Stress Increases A₁ Adenosine Receptor Expression by Activating Nuclear Factor κB

  Zhongzhen Nie, Yun Mei, Mary Ford, Leonard Rybak, Adrianna Marcuzzi, Hongzu Ren, Gary L. Stiles and Vickram Ramkumar

  Molecular Pharmacology April 1998, 53 (4) 663-669; DOI: https://doi.org/10.1124/mol.53.4.663
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  (−)-CGP 12177 Causes Cardiostimulation and Binds to Cardiac Putative β₄-Adrenoceptors in Both Wild-Type and β₃-Adrenoceptor Knockout Mice

  Alberto J. Kaumann, Frédéric Preitner, Doreen Sarsero, Peter Molenaar, Jean-Pierre Revelli and Jean Paul Giacobino

  Molecular Pharmacology April 1998, 53 (4) 670-675; DOI: https://doi.org/10.1124/mol.53.4.670
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  Suppression of Interleukin-2 by the Putative Endogenous Cannabinoid 2-Arachidonyl-Glycerol Is Mediated through Down-regulation of the Nuclear Factor of Activated T Cells

  Yanli Ouyang, Seong Gu Hwang, Seung Hyun Han and Norbert E. Kaminski

  Molecular Pharmacology April 1998, 53 (4) 676-683; DOI: https://doi.org/10.1124/mol.53.4.676
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  N-Methyl-d-Aspartate Attenuates Opioid Receptor-Mediated G Protein Activation and This Process Involves Protein Kinase C

  Guo-Huang Fan, Jing Zhao, Ya-Lan Wu, Li-Guang Lou, Zhe Zhang, Qing Jing, Lan Ma and Gang Pei

  Molecular Pharmacology April 1998, 53 (4) 684-690; DOI: https://doi.org/10.1124/mol.53.4.684
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  Protein Kinase C Activity Is Required for Aryl Hydrocarbon Receptor Pathway-Mediated Signal Transduction

  William Peter Long, Marilyn Pray-Grant, Jo Chao Tsai and Gary H. Perdew

  Molecular Pharmacology April 1998, 53 (4) 691-700; DOI: https://doi.org/10.1124/mol.53.4.691
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  Nuclear Localization of Overexpressed Glyceraldehyde-3-Phosphate Dehydrogenase in Cultured Cerebellar Neurons Undergoing Apoptosis

  Ryoichi Ishitani, Masaharu Tanaka, Katsuyoshi Sunaga, Nobuo Katsube and De-Maw Chuang

  Molecular Pharmacology April 1998, 53 (4) 701-707; DOI: https://doi.org/10.1124/mol.53.4.701
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  Human Histamine N-Methyltransferase Pharmacogenetics: Common Genetic Polymorphisms that Alter Activity

  Charles V. Preuss, Thomas C. Wood, Carol L. Szumlanski, Rebecca B. Raftogianis, Diane M. Otterness, Blanka Girard, Mary C. Scott and Richard M. Weinshilboum

  Molecular Pharmacology April 1998, 53 (4) 708-717; DOI: https://doi.org/10.1124/mol.53.4.708
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  Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Fetal Bovine Serum Acetylcholinesterase by Monoquaternary and Bisquaternary Ligands

  Chunyuan Luo, Yacov Ashani and Bhupendra P. Doctor

  Molecular Pharmacology April 1998, 53 (4) 718-726; DOI: https://doi.org/10.1124/mol.53.4.718
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  ATP Derivatives Are Antagonists of the P2Y₁ Receptor: Similarities to the Platelet ADP Receptor

  Béatrice Hechler, Paul Vigne, Catherine Léon, Jean-Philippe Breittmayer, Christian Gachet and Christian Frelin

  Molecular Pharmacology April 1998, 53 (4) 727-733; DOI: https://doi.org/10.1124/mol.53.4.727
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  Plasma Membrane Depolarization and Disturbed Na⁺Homeostasis Induced by the Protonophore Carbonyl Cyanide-p-trifluoromethoxyphenyl-hydrazon in Isolated Nerve Terminals

  Laszlo Tretter, Christos Chinopoulos and Vera Adam-Vizi

  Molecular Pharmacology April 1998, 53 (4) 734-741; DOI: https://doi.org/10.1124/mol.53.4.734
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  Reverse Na⁺/Ca²⁺ Exchange Contributes to Glutamate-Induced Intracellular Ca²⁺ Concentration Increases in Cultured Rat Forebrain Neurons

  Kari R. Hoyt, Stuart R. Arden, Elias Aizenman and Ian J. Reynolds

  Molecular Pharmacology April 1998, 53 (4) 742-749; DOI: https://doi.org/10.1124/mol.53.4.742
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  Identification and Characterization of Two Cysteinyl-Leukotriene High Affinity Binding Sites with Receptor Characteristics in Human Lung Parenchyma

  Valérie Capra, Simonetta Nicosia, Daniela Ragnini, Maurizio Mezzetti, Dietrich Keppler and G. Enrico Rovati

  Molecular Pharmacology April 1998, 53 (4) 750-758; DOI: https://doi.org/10.1124/mol.53.4.750
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  The Relationship between Agonist Intrinsic Activity and the Rate of Endocytosis of Muscarinic Receptors in a Human Neuroblastoma Cell Line

  Philip G. Szekeres, Jennifer A. Koenig and J. Michael Edwardson

  Molecular Pharmacology April 1998, 53 (4) 759-765; DOI: https://doi.org/10.1124/mol.53.4.759
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  The Agonism and Synergistic Potentiation of Weak Partial Agonists by Triethylamine in α₁-Adrenergic Receptor Activation: Evidence for a Salt Bridge as the Initiating Process

  James E. Porter, Stephanie E. Edelmann, David J. Waugh, Michael T. Piascik and Dianne M. Perez

  Molecular Pharmacology April 1998, 53 (4) 766-771; DOI: https://doi.org/10.1124/mol.53.4.766
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  Creating a Functional Opioid Alkaloid Binding Site in the Orphanin FQ Receptor through Site-Directed Mutagenesis

  Fan Meng, Yasuko Ueda, Mary T. Hoversten, Larry P. Taylor, Rainer K. Reinscheid, Frederick J. Monsma, Stanley J. Watson, Olivier Civelli and Huda Akil

  Molecular Pharmacology April 1998, 53 (4) 772-777; DOI: https://doi.org/10.1124/mol.53.4.772
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  The G Protein-Coupling Profile of Metabotropic Glutamate Receptors, as Determined with Exogenous G Proteins, Is Independent of Their Ligand Recognition Domain

  Marie-Laure Parmentier, Cécile Joly, Sophie Restituito, Joël Bockaert, Yves Grau and Jean-Philippe Pin

  Molecular Pharmacology April 1998, 53 (4) 778-786; DOI: https://doi.org/10.1124/mol.53.4.778
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  Residues at the Subunit Interfaces of the Nicotinic Acetylcholine Receptor That Contribute to α-Conotoxin M1 Binding

  Naoya Sugiyama, Pascale Marchot, Chiaki Kawanishi, Hitoshi Osaka, Brian Molles, Steven M. Sine and Palmer Taylor

  Molecular Pharmacology April 1998, 53 (4) 787-794; DOI: https://doi.org/10.1124/mol.53.4.787
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  Molecular Actions of a Mn(III)Porphyrin Superoxide Dismutase Mimetic and Peroxynitrite Scavenger: Reaction with Nitric Oxide and Direct Inhibition of NO Synthase and Soluble Guanylyl Cyclase

  Silvia Pfeiffer, Astrid Schrammel, Doris Koesling, Kurt Schmidt and Bernd Mayer

  Molecular Pharmacology April 1998, 53 (4) 795-800; DOI: https://doi.org/10.1124/mol.53.4.795