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Molecular Pharmacology

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Table of Contents

July 01, 1998; Volume 54,Issue 1

Articles

  • You have access
    J-104,871, a Novel Farnesyltransferase Inhibitor, Blocks Ras Farnesylation In Vivo in a Farnesyl Pyrophosphate-Competitive Manner
    Mari Yonemoto, Toshihiko Satoh, Hiroharu Arakawa, Ikuko Suzuki-Takahashi, Yoshiaki Monden, Tsutomu Kodera, Kenji Tanaka, Tetsuya Aoyama, Yoshikazu Iwasawa, Toshio Kamei, Susumu Nishimura and Koji Tomimoto
    Molecular Pharmacology July 1998, 54 (1) 1-7; DOI: https://doi.org/10.1124/mol.54.1.1
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    Yeast Expressed Cytochrome P450 2D6 (CYP2D6) Exposed on the External Face of Plasma Membrane Is Functionally Competent
    Jacqueline Loeper, Bénédicte Louérat-Oriou, Catherine Duport and Denis Pompon
    Molecular Pharmacology July 1998, 54 (1) 8-13; DOI: https://doi.org/10.1124/mol.54.1.8
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    Protein Kinase C-Mediated Down-Regulation of β1-Adrenergic Receptor Gene Expression in Rat C6 Glioma Cells
    Zhongwei Li, Vidita A. Vaidya, John D. Alvaro, Philip A. Iredale, Richard Hsu, Ginger Hoffman, Laura Fitzgerald, Patricia K. Curran, Curtis A. Machida, Peter H. Fishman and Ronald S. Duman
    Molecular Pharmacology July 1998, 54 (1) 14-21; DOI: https://doi.org/10.1124/mol.54.1.14
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    Isoquinolines as Antagonists of the P2X7 Nucleotide Receptor: High Selectivity for the Human versus Rat Receptor Homologues
    Benjamin D. Humphreys, Caterina Virginio, Annmarie Surprenant, Janet Rice and George R. Dubyak
    Molecular Pharmacology July 1998, 54 (1) 22-32; DOI: https://doi.org/10.1124/mol.54.1.22
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    Photoaffinity Labeling of the Benzodiazepine Binding Site of α1β3γ2 γ-Aminobutyric AcidA Receptors with Flunitrazepam Identifies a Subset of Ligands that Interact Directly with His102 of the α Subunit and Predicts Orientation of These within the Benzodiazepine Pharmacophore
    Ruth M. McKernan, Sophie Farrar, Ian Collins, Frances Emms, Ayodeji Asuni, Kathleen Quirk and Howard Broughton
    Molecular Pharmacology July 1998, 54 (1) 33-43; DOI: https://doi.org/10.1124/mol.54.1.33
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    Phosphorylation and Functional Desensitization of the α2A-Adrenergic Receptor by Protein Kinase C
    Mei Liang, Margaret G. Eason, Elizabeth A. Jewell-Motz, Mark A. Williams, Cheryl T. Theiss, Gerald W. Dorn and Stephen B. Liggett
    Molecular Pharmacology July 1998, 54 (1) 44-49; DOI: https://doi.org/10.1124/mol.54.1.44
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    Protein-Linked DNA Strand Breaks Induced by NSC 314622, a Novel Noncamptothecin Topoisomerase I Poison
    Glenda Kohlhagen, Kenneth D. Paull, Mark Cushman, Pamela Nagafuji and Yves Pommier
    Molecular Pharmacology July 1998, 54 (1) 50-58; DOI: https://doi.org/10.1124/mol.54.1.50
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    A Crucial Role for the Mitogen-Activated Protein Kinase Pathway in Nicotinic Cholinergic Signaling to Secretory Protein Transcription in Pheochromocytoma Cells
    Kechun Tang, Hongjiang Wu, Sushil K. Mahata and Daniel T. O’Connor
    Molecular Pharmacology July 1998, 54 (1) 59-69; DOI: https://doi.org/10.1124/mol.54.1.59
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    Sphingosine Kinase Mediates Cyclic AMP Suppression of Apoptosis in Rat Periosteal Cells
    Mohamed Machwate, Sevgi B. Rodan, Gideon A. Rodan and Shun-Ichi Harada
    Molecular Pharmacology July 1998, 54 (1) 70-77; DOI: https://doi.org/10.1124/mol.54.1.70
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    Etoposide Targets Topoisomerase IIα and IIβ in Leukemic Cells: Isoform-Specific Cleavable Complexes Visualized and QuantifiedIn Situ by a Novel Immunofluorescence Technique
    E. Willmore, A. J. Frank, K. Padget, M. J. Tilby and C. A. Austin
    Molecular Pharmacology July 1998, 54 (1) 78-85; DOI: https://doi.org/10.1124/mol.54.1.78
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    Point Mutation in Intron Sequence Causes Altered Carboxyl-Terminal Structure in the Aryl Hydrocarbon Receptor of the Most 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Resistant Rat Strain
    Raimo Pohjanvirta, Judy M. Y. Wong, Wei Li, Patricia A. Harper, Jouko Tuomisto and Allan B. Okey
    Molecular Pharmacology July 1998, 54 (1) 86-93; DOI: https://doi.org/10.1124/mol.54.1.86
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    Effector Pathway-Dependent Relative Efficacy at Serotonin Type 2A and 2C Receptors: Evidence for Agonist-Directed Trafficking of Receptor Stimulus
    Kelly A. Berg, Saul Maayani, Joseph Goldfarb, Clare Scaramellini, Paul Leff and William P. Clarke
    Molecular Pharmacology July 1998, 54 (1) 94-104; DOI: https://doi.org/10.1124/mol.54.1.94
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    Differential Response of Estrogen Receptor α and Estrogen Receptor β to Partial Estrogen Agonists/Antagonists
    Tomas Barkhem, Bo Carlsson, Yvonne Nilsson, Eva Enmark, Jan-Åke Gustafsson and Stefan Nilsson
    Molecular Pharmacology July 1998, 54 (1) 105-112; DOI: https://doi.org/10.1124/mol.54.1.105
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    Molecular Basis for the Lack of HERG K+ Channel Block-Related Cardiotoxicity by the H1 Receptor Blocker Cetirizine Compared with Other Second-Generation Antihistamines
    Maurizio Taglialatela, Anna Pannaccione, Pasqualina Castaldo, Giovanna Giorgio, Zhengfeng Zhou, Craig T. January, Arturo Genovese, Gianni Marone and Lucio Annunziato
    Molecular Pharmacology July 1998, 54 (1) 113-121; DOI: https://doi.org/10.1124/mol.54.1.113
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    Regulation of Adenylyl Cyclase Type V/VI in Smooth Muscle: Interplay of Inhibitory G Protein and Ca2+ Influx
    Karnam S. Murthy and Gabriel M. Makhlouf
    Molecular Pharmacology July 1998, 54 (1) 122-128; DOI: https://doi.org/10.1124/mol.54.1.122
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    Ligand Specificity of the Genetic Variants of Human α1-Acid Glycoprotein: Generation of a Three-Dimensional Quantitative Structure-Activity Relationship Model for Drug Binding to the A Variant
    Françoise Hervé, Giulia Caron, Jean-Claude Duché, Patrick Gaillard, Noorsaadah Abd. Rahman, Anna Tsantili-Kakoulidou, Pierre-Alain Carrupt, Philippe d’Athis, Jean-Paul Tillement and Bernard Testa
    Molecular Pharmacology July 1998, 54 (1) 129-138; DOI: https://doi.org/10.1124/mol.54.1.129
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    Identification of a [3H]Ligand for the Common Allosteric Site of Muscarinic Acetylcholine M2 Receptors
    Christian Tränkle, Elisabeth Mies-Klomfass, Mario H. Botero Cid, Ulrike Holzgrabe and Klaus Mohr
    Molecular Pharmacology July 1998, 54 (1) 139-145; DOI: https://doi.org/10.1124/mol.54.1.139
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    Mutations at Lipid-Exposed Residues of the Acetylcholine Receptor Affect Its Gating Kinetics
    Cecilia Bouzat, Ana M. Roccamo, Ingrid Garbus and F. J. Barrantes
    Molecular Pharmacology July 1998, 54 (1) 146-153; DOI: https://doi.org/10.1124/mol.54.1.146
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    Chimeric Melanocortin MC1 and MC3 Receptors: Identification of Domains Participating in Binding of Melanocyte-Stimulating Hormone Peptides
    Helgi B. Schiöth, Philip Yook, Ruta Muceniece, Jarl E. S. Wikberg and Michael Szardenings
    Molecular Pharmacology July 1998, 54 (1) 154-161; DOI: https://doi.org/10.1124/mol.54.1.154
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    Structural Determinants of Potency and Stereoselective Block of hKv1.5 Channels Induced by Local Anesthetics
    Mónica Longobardo, Eva Delpón, Ricardo Caballero, Juan Tamargo and Carmen Valenzuela
    Molecular Pharmacology July 1998, 54 (1) 162-169; DOI: https://doi.org/10.1124/mol.54.1.162
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    Access to Hematin: The Basis of Chloroquine Resistance
    Patrick G. Bray, Mathirut Mungthin, Robert G. Ridley and Stephen A. Ward
    Molecular Pharmacology July 1998, 54 (1) 170-179; DOI: https://doi.org/10.1124/mol.54.1.170
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    Human Platelets and Polymorphonuclear Leukocytes Synthesize Oxygenated Derivatives of Arachidonylethanolamide (Anandamide): Their Affinities for Cannabinoid Receptors and Pathways of Inactivation
    William S. Edgemond, Cecilia J. Hillard, J. R. Falck, Christopher S. Kearn and William B. Campbell
    Molecular Pharmacology July 1998, 54 (1) 180-188; DOI: https://doi.org/10.1124/mol.54.1.180
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    Molecular Basis for Differential Inhibition of Glutamate Transporter Subtypes by Zinc Ions
    Robert J. Vandenberg, Ann D. Mitrovic and Graham A. R. Johnston
    Molecular Pharmacology July 1998, 54 (1) 189-196; DOI: https://doi.org/10.1124/mol.54.1.189
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    The Biophysical and Pharmacological Characteristics of Skeletal Muscle ATP-Sensitive K+ Channels Are Modified in K+-Depleted Rat, an Animal Model of Hypokalemic Periodic Paralysis
    Domenico Tricarico, Sabata Pierno, Rosanna Mallamaci, Giovanni Siro Brigiani, Raffaele Capriulo, Giuseppe Santoro and Diana Conte Camerino
    Molecular Pharmacology July 1998, 54 (1) 197-206; DOI: https://doi.org/10.1124/mol.54.1.197
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    Activation of Soluble Guanylyl Cyclase by the Nitrovasodilator 3-Morpholinosydnonimine Involves Formation ofS-Nitrosoglutathione
    Astrid Schrammel, Silvia Pfeiffer, Kurt Schmidt, Doris Koesling and Bernd Mayer
    Molecular Pharmacology July 1998, 54 (1) 207-212; DOI: https://doi.org/10.1124/mol.54.1.207
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    Sensitivity to Cisplatin and Platinum-Containing Compounds ofSchizosaccharomyces pombe Rad Mutants
    Paola Perego, Franco Zunino, Nives Carenini, Fernando Giuliani, Silvano Spinelli and Stephen B. Howell
    Molecular Pharmacology July 1998, 54 (1) 213-219; DOI: https://doi.org/10.1124/mol.54.1.213
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    A Novel Benzodiazepine that Activates Cardiac Slow Delayed Rectifier K+ Currents
    Joseph J. Salata, Nancy K. Jurkiewicz, Jixin Wang, Ben E. Evans, Heidi T. Orme and Michael C. Sanguinetti
    Molecular Pharmacology July 1998, 54 (1) 220-230; DOI: https://doi.org/10.1124/mol.54.1.220
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Molecular Pharmacology: 54 (1)
Molecular Pharmacology
Vol. 54, Issue 1
1 Jul 1998
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