Table of Contents

Articles

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  Identification of a New Amino Acid Residue Capable of Modulating Agonist Efficacy at the Homomeric Nicotinic Acetylcholine Receptor, α7

  Raymond W. Vazquez and Robert E. Oswald

  Molecular Pharmacology January 1999, 55 (1) 1-7; DOI: https://doi.org/10.1124/mol.55.1.1
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  Δ⁹-Tetrahydrocannabinol Acts as a Partial Agonist to Modulate Glutamatergic Synaptic Transmission between Rat Hippocampal Neurons in Culture

  Maoxing Shen and Stanley A. Thayer

  Molecular Pharmacology January 1999, 55 (1) 8-13; DOI: https://doi.org/10.1124/mol.55.1.8
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  Analysis of a Phenobarbital-Responsive Enhancer Sequence Located in the 5′ Flanking Region of the Chicken CYP2H1 Gene: Identification and Characterization of Functional Protein-Binding Sites

  Satish C. Dogra, Benjamin P. Davidson and Brian K. May

  Molecular Pharmacology January 1999, 55 (1) 14-22; DOI: https://doi.org/10.1124/mol.55.1.14
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  L-Type Calcium Channels Contribute to the Tottering Mouse Dystonic Episodes

  Daniel B. Campbell and Ellen J. Hess

  Molecular Pharmacology January 1999, 55 (1) 23-31; DOI: https://doi.org/10.1124/mol.55.1.23
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  Interactions of Cyclosporin A with Phospholipid Membranes: Effect of Cholesterol

  Tim Söderlund, Jukka Y. A. Lehtonen and Paavo K. J. Kinnunen

  Molecular Pharmacology January 1999, 55 (1) 32-38; DOI: https://doi.org/10.1124/mol.55.1.32
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  Ethanol Modulation of Nicotinic Acetylcholine Receptor Currents in Cultured Cortical Neurons

  Gary L. Aistrup, William Marszalec and Toshio Narahashi

  Molecular Pharmacology January 1999, 55 (1) 39-49; DOI: https://doi.org/10.1124/mol.55.1.39
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  Phosphodiesterase 4B Gene Transcription Is Activated by Lipopolysaccharide and Inhibited by Interleukin-10 in Human Monocytes

  Dongmin Ma, Ping Wu, Robert W. Egan, M. Motasim Billah and Peng Wang

  Molecular Pharmacology January 1999, 55 (1) 50-57; DOI: https://doi.org/10.1124/mol.55.1.50
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  Ligand Binding and Activation of Rat Nicotinic α4β2 Receptors Stably Expressed in HEK293 Cells

  Kimberley Sabey, Ken Paradiso, Jessie Zhang and Joe Henry Steinbach

  Molecular Pharmacology January 1999, 55 (1) 58-66; DOI: https://doi.org/10.1124/mol.55.1.58
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  Activity of Different Bicyclam Derivatives against Human Immunodeficiency Virus Depends on Their Interaction with the CXCR4 Chemokine Receptor

  José A. Esté, Cecilia Cabrera, Erik De Clercq, Sofie Struyf, Jo Van Damme, Gary Bridger, Renato T. Skerlj, Michael J. Abrams, Geoffrey Henson, Arantxa Gutierrez, Bonaventura Clotet and Dominique Schols

  Molecular Pharmacology January 1999, 55 (1) 67-73; DOI: https://doi.org/10.1124/mol.55.1.67
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  In Vivo Involvement of Heparan Sulfate Proteoglycan in the Bioavailability, Internalization, and Catabolism of Exogenous Basic Fibroblast Growth Factor

  Sylvie Colin, Jean-Claude Jeanny, Frederic Mascarelli, Raymond Vienet, Salman Al-Mahmood, Yves Courtois and Jean Labarre

  Molecular Pharmacology January 1999, 55 (1) 74-82; DOI: https://doi.org/10.1124/mol.55.1.74
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  An Improved Cocaine Hydrolase: The A328Y Mutant of Human Butyrylcholinesterase is 4-fold More Efficient

  Weihua Xie, Cibby Varkey Altamirano, Cynthia F. Bartels, Robert J. Speirs, John R. Cashman and Oksana Lockridge

  Molecular Pharmacology January 1999, 55 (1) 83-91; DOI: https://doi.org/10.1124/mol.55.1.83
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  Constitutive Activation of the Human Bradykinin B₂Receptor Induced by Mutations in Transmembrane Helices III and VI

  Jacky Marie, Caroline Koch, Didier Pruneau, Jean-Luc Paquet, Thierry Groblewski, Renée Larguier, Colette Lombard, Benoît Deslauriers, Bernard Maigret and Jean-Claude Bonnafous

  Molecular Pharmacology January 1999, 55 (1) 92-101; DOI: https://doi.org/10.1124/mol.55.1.92
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  Novel Modulation of a Nicotinic Receptor Channel Mutant Reveals that the Open State Is Stabilized by Ethanol

  Stuart A. Forman and Qing Zhou

  Molecular Pharmacology January 1999, 55 (1) 102-108; DOI: https://doi.org/10.1124/mol.55.1.102
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  Acyclophostin: A Ribose-Modified Analog of Adenophostin A with High Affinity for Inositol 1,4,5-Trisphosphate Receptors and pH-Dependent Efficacy

  Mike D. Beecroft, Jonathan S. Marchant, Andrew M. Riley, Nicole C. R. Van Straten, Gijs A. Van der Marel, Jacques H. Van Boom, Barry V. L. Potter and Colin W. Taylor

  Molecular Pharmacology January 1999, 55 (1) 109-117; DOI: https://doi.org/10.1124/mol.55.1.109
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  Daunorubicin- and Mitoxantrone-Triggered Phosphatidylcholine Hydrolysis: Implication in Drug-Induced Ceramide Generation and Apoptosis

  Ali Bettaïeb, Isabelle Plo, Véronique Mansat-De Mas, Anne Quillet-Mary, Thierry Levade, Guy Laurent and Jean-Pierre Jaffrézou

  Molecular Pharmacology January 1999, 55 (1) 118-125; DOI: https://doi.org/10.1124/mol.55.1.118
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  Possible Involvement of Cell Surface Receptors in Sphingosine 1-Phosphate-Induced Activation of Extracellular Signal-Regulated Kinase in C6 Glioma Cells

  Koichi Sato, Hideaki Tomura, Yasuyuki Igarashi, Michio Ui and Fumikazu Okajima

  Molecular Pharmacology January 1999, 55 (1) 126-133; DOI: https://doi.org/10.1124/mol.55.1.126
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  A Molecular Basis for the Different Local Anesthetic Affinities of Resting Versus Open and Inactivated States of the Sodium Channel

  Hong-Ling Li, Adriana Galue, Laurence Meadows and David S. Ragsdale

  Molecular Pharmacology January 1999, 55 (1) 134-141; DOI: https://doi.org/10.1124/mol.55.1.134
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  Angiotensin II Receptor Coupling to Phospholipase D Is Mediated by the βγ Subunits of Heterotrimeric G Proteins in Vascular Smooth Muscle Cells

  Masuko Ushio-Fukai, R. Wayne Alexander, Marjorie Akers, P. Reid Lyons, Bernard Lassègue and Kathy K. Griendling

  Molecular Pharmacology January 1999, 55 (1) 142-149; DOI: https://doi.org/10.1124/mol.55.1.142
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  Local Anesthetics Inhibit the G Protein-Mediated Modulation of K⁺ and Ca⁺⁺ Currents in Anterior Pituitary Cells

  Zhiling Xiong, Cuneyt Bukusoglu and Gary R. Strichartz

  Molecular Pharmacology January 1999, 55 (1) 150-158; DOI: https://doi.org/10.1124/mol.55.1.150
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  Aminotriarylmethane Dyes Are High-Affinity Noncompetitive Antagonists of the Nicotinic Acetylcholine Receptor

  Monica M. Lurtz and Steen E. Pedersen

  Molecular Pharmacology January 1999, 55 (1) 159-167; DOI: https://doi.org/10.1124/mol.55.1.159
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  Spontaneous and γ-Aminobutyric Acid (GABA)-Activated GABA_A Receptor Channels Formed by ε Subunit-Containing Isoforms

  Torben R. Neelands, Janet L. Fisher, Matt Bianchi and Robert L. Macdonald

  Molecular Pharmacology January 1999, 55 (1) 168-178; DOI: https://doi.org/10.1124/mol.55.1.168
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  Site-Directed Mutagenesis of Predicted Active Site Residues in Glutamate Carboxypeptidase II

  Henry S. Speno, Ruth Luthi-Carter, Wendy L. Macias, Stacey L. Valentine, Amit R. T. Joshi and Joseph T. Coyle

  Molecular Pharmacology January 1999, 55 (1) 179-185; DOI: https://doi.org/10.1124/mol.55.1.179
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  Impediment to Calcium Influx and Reactive Oxygen Production Accounts for the Inhibition of Neutrophil Mac-1 Up-Regulation and Adhesion by Tetrandrine

  Yuh-Chiang Shen, Chieh-Fu Chen, Sheng-Yuan Wang and Yen-Jen Sung

  Molecular Pharmacology January 1999, 55 (1) 186-193; DOI: https://doi.org/10.1124/mol.55.1.186