Table of Contents

Articles

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  Selective Substrates for Non-Neuronal Monoamine Transporters

  Dirk Gründemann, Gernot Liebich, Nicholas Kiefer, Sandra Köster and Edgar Schömig

  Molecular Pharmacology July 1999, 56 (1) 1-10; DOI: https://doi.org/10.1124/mol.56.1.1
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  Functional α6-Containing Nicotinic Receptors Are Present in Chick Retina

  Silvia Vailati, Wolfgang Hanke, Andreea Bejan, Benedetta Barabino, Renato Longhi, Barbara Balestra, Milena Moretti, Francesco Clementi and Cecilia Gotti

  Molecular Pharmacology July 1999, 56 (1) 11-19; DOI: https://doi.org/10.1124/mol.56.1.11
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  DNA Interactions of New Antitumor Aminophosphine Platinum(II) Complexes

  Kamila Neplechová, Jana Kašpárková, Oldřich Vrána, Olga Nováková, Abraha Habtemariam, Beth Watchman, Peter J. Sadler and Viktor Brabec

  Molecular Pharmacology July 1999, 56 (1) 20-30; DOI: https://doi.org/10.1124/mol.56.1.20
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  Characterization and Implications of Estrogenic Down-Regulation of Human Catechol-O-Methyltransferase Gene Transcription

  Tao Xie, Shu-Leong Ho and David Ramsden

  Molecular Pharmacology July 1999, 56 (1) 31-38; DOI: https://doi.org/10.1124/mol.56.1.31
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  Inhibition of Calcium/Calmodulin-Dependent Protein Kinase II in Rat Hippocampus Attenuates Morphine Tolerance and Dependence

  Guo-Huang Fan, Ling-Zhi Wang, Hao-Chun Qiu, Lan Ma and Gang Pei

  Molecular Pharmacology July 1999, 56 (1) 39-45; DOI: https://doi.org/10.1124/mol.56.1.39
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  Mimicry in Primary Rat Hepatocyte Cultures of the In Vivo Perivenous Induction by Phenobarbital of Cytochrome P-450 2B1 mRNA: Role of Epidermal Growth Factor and Perivenous Oxygen Tension

  T. Kietzmann, K. I. Hirsch-Ernst, G. F. Kahl and K. Jungermann

  Molecular Pharmacology July 1999, 56 (1) 46-53; DOI: https://doi.org/10.1124/mol.56.1.46
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  Humanization of Mouse 5-Hydroxytryptamine_1B Receptor Gene by Homologous Recombination: In Vitro and In Vivo Characterization

  P. Bonaventure, L. Umans, M. H. M. Bakker, P. Cras, X. Langlois, W. H. M. L. Luyten, A. A. H. P. Megens, L. Serneels, F. Van Leuven and J. E. Leysen

  Molecular Pharmacology July 1999, 56 (1) 54-67; DOI: https://doi.org/10.1124/mol.56.1.54
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  Pattern of Mutations that Results in Loss of Reduced Folate Carrier Function under Antifolate Selective Pressure Augmented by Chemical Mutagenesis

  Rongbao Zhao, Iraida G. Sharina and I. David Goldman

  Molecular Pharmacology July 1999, 56 (1) 68-76; DOI: https://doi.org/10.1124/mol.56.1.68
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  Topoisomerase Poisoning Activity of Novel Disaccharide Anthracyclines

  Fulvio Guano, Philippe Pourquier, Stella Tinelli, Monica Binaschi, Mario Bigioni, Fabio Animati, Stefano Manzini, Franco Zunino, Glenda Kohlhagen, Yves Pommier and Giovanni Capranico

  Molecular Pharmacology July 1999, 56 (1) 77-84; DOI: https://doi.org/10.1124/mol.56.1.77
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  Ethanol Inhibition of Synaptically Evoked Kainate Responses in Rat Hippocampal CA3 Pyramidal Neurons

  Jeff L. Weiner, Thomas V. Dunwiddie and C. Fernando Valenzuela

  Molecular Pharmacology July 1999, 56 (1) 85-90; DOI: https://doi.org/10.1124/mol.56.1.85
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  Endrin Inhibits Adipocyte Differentiation by Selectively Altering Expression Pattern of CCAAT/Enhancer Binding Protein-α in 3T3-L1 Cells

  Maria J. Moreno-Aliaga and Fumio Matsumura

  Molecular Pharmacology July 1999, 56 (1) 91-101; DOI: https://doi.org/10.1124/mol.56.1.91
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  Dithiothreitol Enhances Arsenic Trioxide-Induced Apoptosis in NB4 Cells

  Jia-Ran Gurr, Da-Tian Bau, Fount Liu, Shugene Lynn and Kun-Yan Jan

  Molecular Pharmacology July 1999, 56 (1) 102-109; DOI: https://doi.org/10.1124/mol.56.1.102
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  Preferential Coassembly of α4 and δ Subunits of the γ-Aminobutyric Acid_A Receptor in Rat Thalamus

  Cyrille Sur, Sophie J. Farrar, Julie Kerby, Paul J. Whiting, John R. Atack and Ruth M. McKernan

  Molecular Pharmacology July 1999, 56 (1) 110-115; DOI: https://doi.org/10.1124/mol.56.1.110
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  Modulation of Expression of Endothelial Nitric Oxide Synthase by Nordihydroguaiaretic Acid, a Phenolic Antioxidant in Cultured Endothelial Cells

  Santhini Ramasamy, Grant R. Drummond, Joon Ahn, Michal Storek, Jan Pohl, Sampath Parthasarathy and David G. Harrison

  Molecular Pharmacology July 1999, 56 (1) 116-123; DOI: https://doi.org/10.1124/mol.56.1.116
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  Inhibition of Cyclic GMP-Binding Cyclic GMP-Specific Phosphodiesterase (Type 5) by Sildenafil and Related Compounds

  Illarion V. Turko, Stephen A. Ballard, Sharron H. Francis and Jackie D. Corbin

  Molecular Pharmacology July 1999, 56 (1) 124-130; DOI: https://doi.org/10.1124/mol.56.1.124
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  Farnesol and Geranylgeraniol Prevent Activation of Caspases by Aminobisphosphonates: Biochemical Evidence for Two Distinct Pharmacological Classes of Bisphosphonate Drugs

  Helena L. Benford, Julie C. Frith, Seppo Auriola, Jukka Mönkkönen and Michael J. Rogers

  Molecular Pharmacology July 1999, 56 (1) 131-140; DOI: https://doi.org/10.1124/mol.56.1.131
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  Cross-Resistance to Ionizing Radiation in a Murine Leukemic Cell Line Resistant to cis-Dichlorodiammineplatinum(II): Role of Ku Autoantigen

  Philippe Frit, Yvan Canitrot, Catherine Muller, Nicolas Foray, Patrick Calsou, Elisabetta Marangoni, Jean Bourhis and Bernard Salles

  Molecular Pharmacology July 1999, 56 (1) 141-146; DOI: https://doi.org/10.1124/mol.56.1.141
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  Induction of Alkylator (Melphalan) Resistance in HL60 Cells Is Accompanied by Increased Levels of Topoisomerase II Expression and Function

  Q. Q. Pu and W. R. Bezwoda

  Molecular Pharmacology July 1999, 56 (1) 147-153; DOI: https://doi.org/10.1124/mol.56.1.147
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  Abnormal Regulation of the Sympathetic Nervous System in α_2A-Adrenergic Receptor Knockout Mice

  John D. Altman, Anne U. Trendelenburg, Leigh MacMillan, Dan Bernstein, Lee Limbird, Klaus Starke, Brian K. Kobilka and Lutz Hein

  Molecular Pharmacology July 1999, 56 (1) 154-161; DOI: https://doi.org/10.1124/mol.56.1.154
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  Both Inducible and Constitutive Activator Protein-1-Like Transcription Factors Are Used for Transcriptional Activation of the Galanin Gene by Different First and Second Messenger Pathways

  Youssef Anouar, Hyeon-Woo Lee and Lee E. Eiden

  Molecular Pharmacology July 1999, 56 (1) 162-169; DOI: https://doi.org/10.1124/mol.56.1.162
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  Phosphodiesterase 4B2 Is the Predominant Phosphodiesterase Species and Undergoes Differential Regulation of Gene Expression in Human Monocytes and Neutrophils

  Peng Wang, Ping Wu, Kathleen M. Ohleth, Robert W. Egan and M. Motasim Billah

  Molecular Pharmacology July 1999, 56 (1) 170-174; DOI: https://doi.org/10.1124/mol.56.1.170
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  Mutation of a Highly Conserved Aspartic Acid in the β₂ Adrenergic Receptor: Constitutive Activation, Structural Instability, and Conformational Rearrangement of Transmembrane Segment 6

  Søren G.F. Rasmussen, Anne D. Jensen, George Liapakis, Pejman Ghanouni, Jonathan A. Javitch and Ulrik Gether

  Molecular Pharmacology July 1999, 56 (1) 175-184; DOI: https://doi.org/10.1124/mol.56.1.175
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  The Staurosporine-Like Compound L-753,000 (NB-506) Potentiates the Neurotrophic Effects of Neurotrophin-3 by Acting Selectively at the TrkA Receptor

  Scott Pollack, Lisa Young, James Bilsland, Neil Wilkie, Semantha Ellis, Franz Hefti, Howard Broughton and Sarah Harper

  Molecular Pharmacology July 1999, 56 (1) 185-195; DOI: https://doi.org/10.1124/mol.56.1.185
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  The Inhibition of Mammalian 15-Lipoxygenases by the Anti-Inflammatory Drug Ebselen: Dual-Type Mechanism Involving Covalent Linkage and Alteration of the Iron Ligand Sphere

  Matthias Walther, Hermann-Georg Holzhütter, Ralf Jürgen Kuban, Rainer Wiesner, Jörg Rathmann and Hartmut Kühn

  Molecular Pharmacology July 1999, 56 (1) 196-203; DOI: https://doi.org/10.1124/mol.56.1.196
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  Modulation of Fibroblast Growth Factor-2 Receptor Binding, Signaling, and Mitogenic Activity by Heparin-Mimicking Polysulfonated Compounds

  Sandra Liekens, Daria Leali, Johan Neyts, Robert Esnouf, Marco Rusnati, Patrizia Dell’Era, Prabhat C. Maudgal, Erik De Clercq and Marco Presta

  Molecular Pharmacology July 1999, 56 (1) 204-213; DOI: https://doi.org/10.1124/mol.56.1.204
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  Activation Mechanism of Human Oxytocin Receptor: A Combined Study of Experimental and Computer-Simulated Mutagenesis

  Francesca Fanelli, Pascaline Barbier, Deborah Zanchetta, Pier G. de Benedetti and Bice Chini

  Molecular Pharmacology July 1999, 56 (1) 214-225; DOI: https://doi.org/10.1124/mol.56.1.214
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  Human and Rat Liver UDP-Glucuronosyltransferases Are Targets of Ketoprofen Acylglucuronide

  Nadège Terrier, Etienne Benoit, Claire Senay, Françoise Lapicque, Anna Radominska-Pandya, Jacques Magdalou and Sylvie Fournel-Gigleux

  Molecular Pharmacology July 1999, 56 (1) 226-234; DOI: https://doi.org/10.1124/mol.56.1.226
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  Multiple Amylin Receptors Arise from Receptor Activity-Modifying Protein Interaction with the Calcitonin Receptor Gene Product

  George Christopoulos, Katie J. Perry, Maria Morfis, Nanda Tilakaratne, Yongyi Gao, Neil J. Fraser, Martin J. Main, Steven M. Foord and Patrick M. Sexton

  Molecular Pharmacology July 1999, 56 (1) 235-242; DOI: https://doi.org/10.1124/mol.56.1.235