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Index by author

December 01, 1999; Volume 56,Issue 6

A

  1. Akhoundova, Aida

    1. Selectivity of the Polyspecific Cation Transporter rOCT1 Is Changed by Mutation of Aspartate 475 to Glutamate
      Valentin Gorboulev, Christopher Volk, Petra Arndt, Aida Akhoundova and Hermann Koepsell
      Molecular Pharmacology December 1999, 56 (6) 1254-1261; DOI: https://doi.org/10.1124/mol.56.6.1254

  2. Akiyama, Shin-Ichi

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

  3. Amara, Susan G.

    1. Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
      Hans P. Koch, Michael P. Kavanaugh, Christopher S. Esslinger, Noah Zerangue, John M. Humphrey, Susan G. Amara, A. Richard Chamberlin and Richard J. Bridges
      Molecular Pharmacology December 1999, 56 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.56.6.1095

  4. Amatruda, James F.

    1. Domain Interactions Affecting Human DNA Topoisomerase I Catalysis and Camptothecin Sensitivity
      Paola Fiorani, James F. Amatruda, Alessandra Silvestri, Richard H. Butler, Mary-Ann Bjornsti and Piero Benedetti
      Molecular Pharmacology December 1999, 56 (6) 1105-1115; DOI: https://doi.org/10.1124/mol.56.6.1105

  5. Annunziato, Lucio

    1. Modulation of the K+ Channels Encoded by the Human Ether-a-Gogo-Related Gene-1 (hERG1) by Nitric Oxide
      Maurizio Taglialatela, Anna Pannaccione, Silvana Iossa, Pasqualina Castaldo and Lucio Annunziato
      Molecular Pharmacology December 1999, 56 (6) 1298-1308; DOI: https://doi.org/10.1124/mol.56.6.1298

  6. Aoki, Shunji

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

  7. Aoyama, Masako

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

  8. Aquaro, S.

    1. Intracellular Metabolism of CycloSaligenyl 3′-Azido-2′,3′-dideoxythymidine Monophosphate, a Prodrug of 3′-Azido-2′,3′-dideoxythymidine (Zidovudine)
      Jan Balzarini, Lieve Naesens, S. Aquaro, T. Knispel, C.-F. Perno, E. De Clercq and C. Meier
      Molecular Pharmacology December 1999, 56 (6) 1354-1361; DOI: https://doi.org/10.1124/mol.56.6.1354

  9. Arndt, Petra

    1. Selectivity of the Polyspecific Cation Transporter rOCT1 Is Changed by Mutation of Aspartate 475 to Glutamate
      Valentin Gorboulev, Christopher Volk, Petra Arndt, Aida Akhoundova and Hermann Koepsell
      Molecular Pharmacology December 1999, 56 (6) 1254-1261; DOI: https://doi.org/10.1124/mol.56.6.1254

  10. Austin, C. A.

    1. Murine Transgenic Cells Lacking DNA Topoisomerase IIβ Are Resistant to Acridines and Mitoxantrone: Analysis of Cytotoxicity and Cleavable Complex Formation
      F. Errington, E. Willmore, M. J. Tilby, L. Li, G. Li, W. Li, B. C. Baguley and C. A. Austin
      Molecular Pharmacology December 1999, 56 (6) 1309-1316; DOI: https://doi.org/10.1124/mol.56.6.1309

B

  1. Baguley, B. C.

    1. Murine Transgenic Cells Lacking DNA Topoisomerase IIβ Are Resistant to Acridines and Mitoxantrone: Analysis of Cytotoxicity and Cleavable Complex Formation
      F. Errington, E. Willmore, M. J. Tilby, L. Li, G. Li, W. Li, B. C. Baguley and C. A. Austin
      Molecular Pharmacology December 1999, 56 (6) 1309-1316; DOI: https://doi.org/10.1124/mol.56.6.1309

  2. Ballesteros, Juan A.

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  3. Balzarini, Jan

    1. Intracellular Metabolism of CycloSaligenyl 3′-Azido-2′,3′-dideoxythymidine Monophosphate, a Prodrug of 3′-Azido-2′,3′-dideoxythymidine (Zidovudine)
      Jan Balzarini, Lieve Naesens, S. Aquaro, T. Knispel, C.-F. Perno, E. De Clercq and C. Meier
      Molecular Pharmacology December 1999, 56 (6) 1354-1361; DOI: https://doi.org/10.1124/mol.56.6.1354

  4. Benedetti, Piero

    1. Domain Interactions Affecting Human DNA Topoisomerase I Catalysis and Camptothecin Sensitivity
      Paola Fiorani, James F. Amatruda, Alessandra Silvestri, Richard H. Butler, Mary-Ann Bjornsti and Piero Benedetti
      Molecular Pharmacology December 1999, 56 (6) 1105-1115; DOI: https://doi.org/10.1124/mol.56.6.1105

  5. Benveniste, Morris

    1. Putative Partial Agonist 1-Aminocyclopropanecarboxylic Acid Acts Concurrently as a Glycine-Site Agonist and a Glutamate-Site Antagonist at N-Methyl-d-aspartate Receptors
      Rinat Nahum-Levy, Linda H. Fossom, Phil Skolnick and Morris Benveniste
      Molecular Pharmacology December 1999, 56 (6) 1207-1218; DOI: https://doi.org/10.1124/mol.56.6.1207

  6. Bevan, Nicola

    1. Visualizing Differences in Ligand Regulation of Wild-Type and Constitutively Active Mutant β2-Adrenoceptor-Green Fluorescent Protein Fusion Proteins
      Alison J. McLean, Nicola Bevan, Stephen Rees and Graeme Milligan
      Molecular Pharmacology December 1999, 56 (6) 1182-1191; DOI: https://doi.org/10.1124/mol.56.6.1182

  7. Bjornsti, Mary-Ann

    1. Domain Interactions Affecting Human DNA Topoisomerase I Catalysis and Camptothecin Sensitivity
      Paola Fiorani, James F. Amatruda, Alessandra Silvestri, Richard H. Butler, Mary-Ann Bjornsti and Piero Benedetti
      Molecular Pharmacology December 1999, 56 (6) 1105-1115; DOI: https://doi.org/10.1124/mol.56.6.1105

  8. Blomenröhr, Marion

    1. Pivotal Role for the Cytoplasmic Carboxyl-Terminal Tail of a Nonmammalian Gonadotropin-Releasing Hormone Receptor in Cell Surface Expression, Ligand Binding, and Receptor Phosphorylation and Internalization
      Marion Blomenröhr, Anders Heding, Robin Sellar, Rob Leurs, Jan Bogerd, Karin A. Eidne and Gary B. Willars
      Molecular Pharmacology December 1999, 56 (6) 1229-1237; DOI: https://doi.org/10.1124/mol.56.6.1229

  9. Bogerd, Jan

    1. Pivotal Role for the Cytoplasmic Carboxyl-Terminal Tail of a Nonmammalian Gonadotropin-Releasing Hormone Receptor in Cell Surface Expression, Ligand Binding, and Receptor Phosphorylation and Internalization
      Marion Blomenröhr, Anders Heding, Robin Sellar, Rob Leurs, Jan Bogerd, Karin A. Eidne and Gary B. Willars
      Molecular Pharmacology December 1999, 56 (6) 1229-1237; DOI: https://doi.org/10.1124/mol.56.6.1229

  10. Bridges, Richard J.

    1. Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
      Hans P. Koch, Michael P. Kavanaugh, Christopher S. Esslinger, Noah Zerangue, John M. Humphrey, Susan G. Amara, A. Richard Chamberlin and Richard J. Bridges
      Molecular Pharmacology December 1999, 56 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.56.6.1095

  11. Bukowski, Ronald M.

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

  12. Burgard, Edward C.

    1. Molecular and Functional Characterization of Human P2X2 Receptors
      Kevin J. Lynch, Edward Touma, Wende Niforatos, Karen L. Kage, Edward C. Burgard, Tim van Biesen, Elizabeth A. Kowaluk and Michael F. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1171-1181; DOI: https://doi.org/10.1124/mol.56.6.1171

  13. Buters, Jeroen T.M.

    1. Bone Marrow Stromal Cell Cytochrome P4501B1 Is Required for Pre-B Cell Apoptosis Induced by 7,12-Dimethylbenz[a]anthracene
      Shawn M. Heidel, Karrie Holston, Jeroen T.M. Buters, Frank J. Gonzalez, Colin R. Jefcoate and Charles J. Czupyrynski
      Molecular Pharmacology December 1999, 56 (6) 1317-1323; DOI: https://doi.org/10.1124/mol.56.6.1317

  14. Butler, Richard H.

    1. Domain Interactions Affecting Human DNA Topoisomerase I Catalysis and Camptothecin Sensitivity
      Paola Fiorani, James F. Amatruda, Alessandra Silvestri, Richard H. Butler, Mary-Ann Bjornsti and Piero Benedetti
      Molecular Pharmacology December 1999, 56 (6) 1105-1115; DOI: https://doi.org/10.1124/mol.56.6.1105

C

  1. Castaldo, Pasqualina

    1. Modulation of the K+ Channels Encoded by the Human Ether-a-Gogo-Related Gene-1 (hERG1) by Nitric Oxide
      Maurizio Taglialatela, Anna Pannaccione, Silvana Iossa, Pasqualina Castaldo and Lucio Annunziato
      Molecular Pharmacology December 1999, 56 (6) 1298-1308; DOI: https://doi.org/10.1124/mol.56.6.1298

  2. Catterall, William A.

    1. Differential Interaction of R-Mexiletine with the Local Anesthetic Receptor Site on Brain and Heart Sodium Channel α-Subunits
      Thomas Weiser, Yusheng Qu, William A. Catterall and Todd Scheuer
      Molecular Pharmacology December 1999, 56 (6) 1238-1244; DOI: https://doi.org/10.1124/mol.56.6.1238

  3. Chamberlin, A. Richard

    1. Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
      Hans P. Koch, Michael P. Kavanaugh, Christopher S. Esslinger, Noah Zerangue, John M. Humphrey, Susan G. Amara, A. Richard Chamberlin and Richard J. Bridges
      Molecular Pharmacology December 1999, 56 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.56.6.1095

  4. Chen, Jiayun

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  5. Chen, Yi-Rong

    1. c-Jun N-Terminal Kinase Mediates Apoptotic Signaling Induced byN-(4-Hydroxyphenyl)retinamide
      Yi-Rong Chen, Guisheng Zhou and Tse-Hua Tan
      Molecular Pharmacology December 1999, 56 (6) 1271-1279; DOI: https://doi.org/10.1124/mol.56.6.1271

  6. Chen, Zhe-Sheng

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

  7. Chiappa, Victor

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  8. Cnudde, Johnny

    1. Different Vasoactive Intestinal Polypeptide Receptor Domains Are Involved in the Selective Recognition of Two VPAC2-Selective Ligands
      Maria G. Juarranz, Jean Van Rampelbergh, Philippe Gourlet, Philippe De Neef, Johnny Cnudde, Patrick Robberecht and Magali Waelbroeck
      Molecular Pharmacology December 1999, 56 (6) 1280-1287; DOI: https://doi.org/10.1124/mol.56.6.1280

  9. Czupyrynski, Charles J.

    1. Bone Marrow Stromal Cell Cytochrome P4501B1 Is Required for Pre-B Cell Apoptosis Induced by 7,12-Dimethylbenz[a]anthracene
      Shawn M. Heidel, Karrie Holston, Jeroen T.M. Buters, Frank J. Gonzalez, Colin R. Jefcoate and Charles J. Czupyrynski
      Molecular Pharmacology December 1999, 56 (6) 1317-1323; DOI: https://doi.org/10.1124/mol.56.6.1317

D

  1. Davarinos, Nikos A.

    1. Analysis of Aryl Hydrocarbon Receptor-Mediated Signaling during Physiological Hypoxia Reveals Lack of Competition for the Aryl Hydrocarbon Nuclear Translocator Transcription Factor
      Richard S. Pollenz, Nikos A. Davarinos and Todd P. Shearer
      Molecular Pharmacology December 1999, 56 (6) 1127-1137; DOI: https://doi.org/10.1124/mol.56.6.1127

  2. De Clercq, E.

    1. Intracellular Metabolism of CycloSaligenyl 3′-Azido-2′,3′-dideoxythymidine Monophosphate, a Prodrug of 3′-Azido-2′,3′-dideoxythymidine (Zidovudine)
      Jan Balzarini, Lieve Naesens, S. Aquaro, T. Knispel, C.-F. Perno, E. De Clercq and C. Meier
      Molecular Pharmacology December 1999, 56 (6) 1354-1361; DOI: https://doi.org/10.1124/mol.56.6.1354

  3. de Koning, Harry P.

    1. Adenosine Transporters in Bloodstream Forms of Trypanosoma brucei brucei: Substrate Recognition Motifs and Affinity for Trypanocidal Drugs
      Harry P. de Koning and Simon M. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1162-1170; DOI: https://doi.org/10.1124/mol.56.6.1162

  4. De Neef, Philippe

    1. Different Vasoactive Intestinal Polypeptide Receptor Domains Are Involved in the Selective Recognition of Two VPAC2-Selective Ligands
      Maria G. Juarranz, Jean Van Rampelbergh, Philippe Gourlet, Philippe De Neef, Johnny Cnudde, Patrick Robberecht and Magali Waelbroeck
      Molecular Pharmacology December 1999, 56 (6) 1280-1287; DOI: https://doi.org/10.1124/mol.56.6.1280

  5. Dodds, Helen M.

    1. The Mechanism for the Inhibition of Acetylcholinesterases by Irinotecan (CPT-11)
      Helen M. Dodds and Laurent P. Rivory
      Molecular Pharmacology December 1999, 56 (6) 1346-1353; DOI: https://doi.org/10.1124/mol.56.6.1346

  6. Downey, Kathleen M.

    1. 9-(2-Phosphonylmethoxyethyl) Derivatives of Purine Nucleotide Analogs: A Comparison of Their Metabolism and Interaction with Cellular DNA Synthesis
      Pavel Kramata and Kathleen M. Downey
      Molecular Pharmacology December 1999, 56 (6) 1262-1270; DOI: https://doi.org/10.1124/mol.56.6.1262

E

  1. Eidne, Karin A.

    1. Pivotal Role for the Cytoplasmic Carboxyl-Terminal Tail of a Nonmammalian Gonadotropin-Releasing Hormone Receptor in Cell Surface Expression, Ligand Binding, and Receptor Phosphorylation and Internalization
      Marion Blomenröhr, Anders Heding, Robin Sellar, Rob Leurs, Jan Bogerd, Karin A. Eidne and Gary B. Willars
      Molecular Pharmacology December 1999, 56 (6) 1229-1237; DOI: https://doi.org/10.1124/mol.56.6.1229

  2. Ellis, John

    1. Site-Directed Mutagenesis Reveals Two Epitopes Involved in the Subtype Selectivity of the Allosteric Interactions of Gallamine at Muscarinic Acetylcholine Receptors
      Ann L. Gnagey, Margaret Seidenberg and John Ellis
      Molecular Pharmacology December 1999, 56 (6) 1245-1253; DOI: https://doi.org/10.1124/mol.56.6.1245

  3. Enyeart, John J.

    1. Mibefradil Potently Blocks ATP-Activated K+ Channels in Adrenal Cells
      Juan Carlos Gomora, Judith A. Enyeart and John J. Enyeart
      Molecular Pharmacology December 1999, 56 (6) 1192-1197; DOI: https://doi.org/10.1124/mol.56.6.1192

  4. Enyeart, Judith A.

    1. Mibefradil Potently Blocks ATP-Activated K+ Channels in Adrenal Cells
      Juan Carlos Gomora, Judith A. Enyeart and John J. Enyeart
      Molecular Pharmacology December 1999, 56 (6) 1192-1197; DOI: https://doi.org/10.1124/mol.56.6.1192

  5. Errington, F.

    1. Murine Transgenic Cells Lacking DNA Topoisomerase IIβ Are Resistant to Acridines and Mitoxantrone: Analysis of Cytotoxicity and Cleavable Complex Formation
      F. Errington, E. Willmore, M. J. Tilby, L. Li, G. Li, W. Li, B. C. Baguley and C. A. Austin
      Molecular Pharmacology December 1999, 56 (6) 1309-1316; DOI: https://doi.org/10.1124/mol.56.6.1309

  6. Esslinger, Christopher S.

    1. Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
      Hans P. Koch, Michael P. Kavanaugh, Christopher S. Esslinger, Noah Zerangue, John M. Humphrey, Susan G. Amara, A. Richard Chamberlin and Richard J. Bridges
      Molecular Pharmacology December 1999, 56 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.56.6.1095

F

  1. Faber, James E.

    1. Platelet-Derived Growth Factor Inhibits α1D-Adrenergic Receptor Expression in Vascular Smooth Muscle Cells In Vitro and Ex Vivo
      Xiaohua Xin, Nengyu Yang and James E. Faber
      Molecular Pharmacology December 1999, 56 (6) 1143-1151; DOI: https://doi.org/10.1124/mol.56.6.1143
    2. Platelet-Derived Growth Factor-BB Inhibits Rat α1D-Adrenergic Receptor Gene Expression in Vascular Smooth Muscle Cells by Inducing AP-2-Like Protein Binding to α1D Proximal Promoter Region
      Xiaohua Xin, Nengyu Yang and James E. Faber
      Molecular Pharmacology December 1999, 56 (6) 1152-1161; DOI: https://doi.org/10.1124/mol.56.6.1152

  2. Fiorani, Paola

    1. Domain Interactions Affecting Human DNA Topoisomerase I Catalysis and Camptothecin Sensitivity
      Paola Fiorani, James F. Amatruda, Alessandra Silvestri, Richard H. Butler, Mary-Ann Bjornsti and Piero Benedetti
      Molecular Pharmacology December 1999, 56 (6) 1105-1115; DOI: https://doi.org/10.1124/mol.56.6.1105

  3. Fossom, Linda H.

    1. Putative Partial Agonist 1-Aminocyclopropanecarboxylic Acid Acts Concurrently as a Glycine-Site Agonist and a Glutamate-Site Antagonist at N-Methyl-d-aspartate Receptors
      Rinat Nahum-Levy, Linda H. Fossom, Phil Skolnick and Morris Benveniste
      Molecular Pharmacology December 1999, 56 (6) 1207-1218; DOI: https://doi.org/10.1124/mol.56.6.1207

  4. Furukawa, Tatsuhiko

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

G

  1. Ganapathi, Mahrukh K.

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

  2. Ganapathi, Ram

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

  3. Glass, Michelle

    1. Agonist Selective Regulation of G Proteins by Cannabinoid CB1 and CB2 Receptors
      Michelle Glass and John K. Northup
      Molecular Pharmacology December 1999, 56 (6) 1362-1369; DOI: https://doi.org/10.1124/mol.56.6.1362

  4. Gnagey, Ann L.

    1. Site-Directed Mutagenesis Reveals Two Epitopes Involved in the Subtype Selectivity of the Allosteric Interactions of Gallamine at Muscarinic Acetylcholine Receptors
      Ann L. Gnagey, Margaret Seidenberg and John Ellis
      Molecular Pharmacology December 1999, 56 (6) 1245-1253; DOI: https://doi.org/10.1124/mol.56.6.1245

  5. Godel, Thierry

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  6. Gomora, Juan Carlos

    1. Mibefradil Potently Blocks ATP-Activated K+ Channels in Adrenal Cells
      Juan Carlos Gomora, Judith A. Enyeart and John J. Enyeart
      Molecular Pharmacology December 1999, 56 (6) 1192-1197; DOI: https://doi.org/10.1124/mol.56.6.1192

  7. Gonzalez, Frank J.

    1. Bone Marrow Stromal Cell Cytochrome P4501B1 Is Required for Pre-B Cell Apoptosis Induced by 7,12-Dimethylbenz[a]anthracene
      Shawn M. Heidel, Karrie Holston, Jeroen T.M. Buters, Frank J. Gonzalez, Colin R. Jefcoate and Charles J. Czupyrynski
      Molecular Pharmacology December 1999, 56 (6) 1317-1323; DOI: https://doi.org/10.1124/mol.56.6.1317

  8. Goodwin, Bryan

    1. The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
      Bryan Goodwin, Ecushla Hodgson and Christopher Liddle
      Molecular Pharmacology December 1999, 56 (6) 1329-1339; DOI: https://doi.org/10.1124/mol.56.6.1329

  9. Gorboulev, Valentin

    1. Selectivity of the Polyspecific Cation Transporter rOCT1 Is Changed by Mutation of Aspartate 475 to Glutamate
      Valentin Gorboulev, Christopher Volk, Petra Arndt, Aida Akhoundova and Hermann Koepsell
      Molecular Pharmacology December 1999, 56 (6) 1254-1261; DOI: https://doi.org/10.1124/mol.56.6.1254

  10. Gourlet, Philippe

    1. Different Vasoactive Intestinal Polypeptide Receptor Domains Are Involved in the Selective Recognition of Two VPAC2-Selective Ligands
      Maria G. Juarranz, Jean Van Rampelbergh, Philippe Gourlet, Philippe De Neef, Johnny Cnudde, Patrick Robberecht and Magali Waelbroeck
      Molecular Pharmacology December 1999, 56 (6) 1280-1287; DOI: https://doi.org/10.1124/mol.56.6.1280

  11. Grabowski, Dale R.

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

  12. Gross, Insa

    1. Stoichiometry of Potassium Channel Opener Action
      Insa Gross, Andreas Toman, Ingo Uhde, Christina Schwanstecher and Mathias Schwanstecher
      Molecular Pharmacology December 1999, 56 (6) 1370-1373; DOI: https://doi.org/10.1124/mol.56.6.1370

H

  1. Hartman, Deborah S.

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  2. Heding, Anders

    1. Pivotal Role for the Cytoplasmic Carboxyl-Terminal Tail of a Nonmammalian Gonadotropin-Releasing Hormone Receptor in Cell Surface Expression, Ligand Binding, and Receptor Phosphorylation and Internalization
      Marion Blomenröhr, Anders Heding, Robin Sellar, Rob Leurs, Jan Bogerd, Karin A. Eidne and Gary B. Willars
      Molecular Pharmacology December 1999, 56 (6) 1229-1237; DOI: https://doi.org/10.1124/mol.56.6.1229

  3. Heidel, Shawn M.

    1. Bone Marrow Stromal Cell Cytochrome P4501B1 Is Required for Pre-B Cell Apoptosis Induced by 7,12-Dimethylbenz[a]anthracene
      Shawn M. Heidel, Karrie Holston, Jeroen T.M. Buters, Frank J. Gonzalez, Colin R. Jefcoate and Charles J. Czupyrynski
      Molecular Pharmacology December 1999, 56 (6) 1317-1323; DOI: https://doi.org/10.1124/mol.56.6.1317

  4. Hickson, Ian D.

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

  5. Hodgson, Ecushla

    1. The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
      Bryan Goodwin, Ecushla Hodgson and Christopher Liddle
      Molecular Pharmacology December 1999, 56 (6) 1329-1339; DOI: https://doi.org/10.1124/mol.56.6.1329

  6. Holmes, Katherine A.

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

  7. Holston, Karrie

    1. Bone Marrow Stromal Cell Cytochrome P4501B1 Is Required for Pre-B Cell Apoptosis Induced by 7,12-Dimethylbenz[a]anthracene
      Shawn M. Heidel, Karrie Holston, Jeroen T.M. Buters, Frank J. Gonzalez, Colin R. Jefcoate and Charles J. Czupyrynski
      Molecular Pharmacology December 1999, 56 (6) 1317-1323; DOI: https://doi.org/10.1124/mol.56.6.1317

  8. Humphrey, John M.

    1. Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
      Hans P. Koch, Michael P. Kavanaugh, Christopher S. Esslinger, Noah Zerangue, John M. Humphrey, Susan G. Amara, A. Richard Chamberlin and Richard J. Bridges
      Molecular Pharmacology December 1999, 56 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.56.6.1095

I

  1. Iossa, Silvana

    1. Modulation of the K+ Channels Encoded by the Human Ether-a-Gogo-Related Gene-1 (hERG1) by Nitric Oxide
      Maurizio Taglialatela, Anna Pannaccione, Silvana Iossa, Pasqualina Castaldo and Lucio Annunziato
      Molecular Pharmacology December 1999, 56 (6) 1298-1308; DOI: https://doi.org/10.1124/mol.56.6.1298

J

  1. Jarvis, Michael F.

    1. Molecular and Functional Characterization of Human P2X2 Receptors
      Kevin J. Lynch, Edward Touma, Wende Niforatos, Karen L. Kage, Edward C. Burgard, Tim van Biesen, Elizabeth A. Kowaluk and Michael F. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1171-1181; DOI: https://doi.org/10.1124/mol.56.6.1171

  2. Jarvis, Simon M.

    1. Adenosine Transporters in Bloodstream Forms of Trypanosoma brucei brucei: Substrate Recognition Motifs and Affinity for Trypanocidal Drugs
      Harry P. de Koning and Simon M. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1162-1170; DOI: https://doi.org/10.1124/mol.56.6.1162

  3. Javitch, Jonathan A.

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  4. Jefcoate, Colin R.

    1. Bone Marrow Stromal Cell Cytochrome P4501B1 Is Required for Pre-B Cell Apoptosis Induced by 7,12-Dimethylbenz[a]anthracene
      Shawn M. Heidel, Karrie Holston, Jeroen T.M. Buters, Frank J. Gonzalez, Colin R. Jefcoate and Charles J. Czupyrynski
      Molecular Pharmacology December 1999, 56 (6) 1317-1323; DOI: https://doi.org/10.1124/mol.56.6.1317

  5. Juarranz, Maria G.

    1. Different Vasoactive Intestinal Polypeptide Receptor Domains Are Involved in the Selective Recognition of Two VPAC2-Selective Ligands
      Maria G. Juarranz, Jean Van Rampelbergh, Philippe Gourlet, Philippe De Neef, Johnny Cnudde, Patrick Robberecht and Magali Waelbroeck
      Molecular Pharmacology December 1999, 56 (6) 1280-1287; DOI: https://doi.org/10.1124/mol.56.6.1280

K

  1. Kage, Karen L.

    1. Molecular and Functional Characterization of Human P2X2 Receptors
      Kevin J. Lynch, Edward Touma, Wende Niforatos, Karen L. Kage, Edward C. Burgard, Tim van Biesen, Elizabeth A. Kowaluk and Michael F. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1171-1181; DOI: https://doi.org/10.1124/mol.56.6.1171

  2. Kavanaugh, Michael P.

    1. Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
      Hans P. Koch, Michael P. Kavanaugh, Christopher S. Esslinger, Noah Zerangue, John M. Humphrey, Susan G. Amara, A. Richard Chamberlin and Richard J. Bridges
      Molecular Pharmacology December 1999, 56 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.56.6.1095

  3. Kawabe, Takeshi

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

  4. Knispel, T.

    1. Intracellular Metabolism of CycloSaligenyl 3′-Azido-2′,3′-dideoxythymidine Monophosphate, a Prodrug of 3′-Azido-2′,3′-dideoxythymidine (Zidovudine)
      Jan Balzarini, Lieve Naesens, S. Aquaro, T. Knispel, C.-F. Perno, E. De Clercq and C. Meier
      Molecular Pharmacology December 1999, 56 (6) 1354-1361; DOI: https://doi.org/10.1124/mol.56.6.1354

  5. Kocarek, Thomas A.

    1. Regulation of Rat Hepatic Hydroxysteroid Sulfotransferase (SULT2-40/41) Gene Expression by Glucocorticoids: Evidence for a Dual Mechanism of Transcriptional Control
      Melissa Runge-Morris, Wei Wu and Thomas A. Kocarek
      Molecular Pharmacology December 1999, 56 (6) 1198-1206; DOI: https://doi.org/10.1124/mol.56.6.1198

  6. Koch, Hans P.

    1. Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
      Hans P. Koch, Michael P. Kavanaugh, Christopher S. Esslinger, Noah Zerangue, John M. Humphrey, Susan G. Amara, A. Richard Chamberlin and Richard J. Bridges
      Molecular Pharmacology December 1999, 56 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.56.6.1095

  7. Koepsell, Hermann

    1. Selectivity of the Polyspecific Cation Transporter rOCT1 Is Changed by Mutation of Aspartate 475 to Glutamate
      Valentin Gorboulev, Christopher Volk, Petra Arndt, Aida Akhoundova and Hermann Koepsell
      Molecular Pharmacology December 1999, 56 (6) 1254-1261; DOI: https://doi.org/10.1124/mol.56.6.1254

  8. Kowaluk, Elizabeth A.

    1. Molecular and Functional Characterization of Human P2X2 Receptors
      Kevin J. Lynch, Edward Touma, Wende Niforatos, Karen L. Kage, Edward C. Burgard, Tim van Biesen, Elizabeth A. Kowaluk and Michael F. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1171-1181; DOI: https://doi.org/10.1124/mol.56.6.1171

  9. Kramata, Pavel

    1. 9-(2-Phosphonylmethoxyethyl) Derivatives of Purine Nucleotide Analogs: A Comparison of Their Metabolism and Interaction with Cellular DNA Synthesis
      Pavel Kramata and Kathleen M. Downey
      Molecular Pharmacology December 1999, 56 (6) 1262-1270; DOI: https://doi.org/10.1124/mol.56.6.1262

  10. Kuwano, Michihiko

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

L

  1. Leurs, Rob

    1. Pivotal Role for the Cytoplasmic Carboxyl-Terminal Tail of a Nonmammalian Gonadotropin-Releasing Hormone Receptor in Cell Surface Expression, Ligand Binding, and Receptor Phosphorylation and Internalization
      Marion Blomenröhr, Anders Heding, Robin Sellar, Rob Leurs, Jan Bogerd, Karin A. Eidne and Gary B. Willars
      Molecular Pharmacology December 1999, 56 (6) 1229-1237; DOI: https://doi.org/10.1124/mol.56.6.1229

  2. Li, G.

    1. Murine Transgenic Cells Lacking DNA Topoisomerase IIβ Are Resistant to Acridines and Mitoxantrone: Analysis of Cytotoxicity and Cleavable Complex Formation
      F. Errington, E. Willmore, M. J. Tilby, L. Li, G. Li, W. Li, B. C. Baguley and C. A. Austin
      Molecular Pharmacology December 1999, 56 (6) 1309-1316; DOI: https://doi.org/10.1124/mol.56.6.1309

  3. Li, L.

    1. Murine Transgenic Cells Lacking DNA Topoisomerase IIβ Are Resistant to Acridines and Mitoxantrone: Analysis of Cytotoxicity and Cleavable Complex Formation
      F. Errington, E. Willmore, M. J. Tilby, L. Li, G. Li, W. Li, B. C. Baguley and C. A. Austin
      Molecular Pharmacology December 1999, 56 (6) 1309-1316; DOI: https://doi.org/10.1124/mol.56.6.1309

  4. Li, W.

    1. Murine Transgenic Cells Lacking DNA Topoisomerase IIβ Are Resistant to Acridines and Mitoxantrone: Analysis of Cytotoxicity and Cleavable Complex Formation
      F. Errington, E. Willmore, M. J. Tilby, L. Li, G. Li, W. Li, B. C. Baguley and C. A. Austin
      Molecular Pharmacology December 1999, 56 (6) 1309-1316; DOI: https://doi.org/10.1124/mol.56.6.1309

  5. Liddle, Christopher

    1. The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
      Bryan Goodwin, Ecushla Hodgson and Christopher Liddle
      Molecular Pharmacology December 1999, 56 (6) 1329-1339; DOI: https://doi.org/10.1124/mol.56.6.1329

  6. Lynch, Kevin J.

    1. Molecular and Functional Characterization of Human P2X2 Receptors
      Kevin J. Lynch, Edward Touma, Wende Niforatos, Karen L. Kage, Edward C. Burgard, Tim van Biesen, Elizabeth A. Kowaluk and Michael F. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1171-1181; DOI: https://doi.org/10.1124/mol.56.6.1171

M

  1. Matsumoto, Yoko

    1. Protective Effects of Triterpene Compounds Against the Cytotoxicity of Cadmium in HepG2 Cells
      Nobuhiko Miura, Yoko Matsumoto, Shinichi Miyairi, Shoji Nishiyama and Akira Naganuma
      Molecular Pharmacology December 1999, 56 (6) 1324-1328; DOI: https://doi.org/10.1124/mol.56.6.1324

  2. McLean, Alison J.

    1. Visualizing Differences in Ligand Regulation of Wild-Type and Constitutively Active Mutant β2-Adrenoceptor-Green Fluorescent Protein Fusion Proteins
      Alison J. McLean, Nicola Bevan, Stephen Rees and Graeme Milligan
      Molecular Pharmacology December 1999, 56 (6) 1182-1191; DOI: https://doi.org/10.1124/mol.56.6.1182

  3. Meier, C.

    1. Intracellular Metabolism of CycloSaligenyl 3′-Azido-2′,3′-dideoxythymidine Monophosphate, a Prodrug of 3′-Azido-2′,3′-dideoxythymidine (Zidovudine)
      Jan Balzarini, Lieve Naesens, S. Aquaro, T. Knispel, C.-F. Perno, E. De Clercq and C. Meier
      Molecular Pharmacology December 1999, 56 (6) 1354-1361; DOI: https://doi.org/10.1124/mol.56.6.1354

  4. Milligan, Graeme

    1. Visualizing Differences in Ligand Regulation of Wild-Type and Constitutively Active Mutant β2-Adrenoceptor-Green Fluorescent Protein Fusion Proteins
      Alison J. McLean, Nicola Bevan, Stephen Rees and Graeme Milligan
      Molecular Pharmacology December 1999, 56 (6) 1182-1191; DOI: https://doi.org/10.1124/mol.56.6.1182

  5. Miura, Nobuhiko

    1. Protective Effects of Triterpene Compounds Against the Cytotoxicity of Cadmium in HepG2 Cells
      Nobuhiko Miura, Yoko Matsumoto, Shinichi Miyairi, Shoji Nishiyama and Akira Naganuma
      Molecular Pharmacology December 1999, 56 (6) 1324-1328; DOI: https://doi.org/10.1124/mol.56.6.1324

  6. Miyairi, Shinichi

    1. Protective Effects of Triterpene Compounds Against the Cytotoxicity of Cadmium in HepG2 Cells
      Nobuhiko Miura, Yoko Matsumoto, Shinichi Miyairi, Shoji Nishiyama and Akira Naganuma
      Molecular Pharmacology December 1999, 56 (6) 1324-1328; DOI: https://doi.org/10.1124/mol.56.6.1324

N

  1. Naesens, Lieve

    1. Intracellular Metabolism of CycloSaligenyl 3′-Azido-2′,3′-dideoxythymidine Monophosphate, a Prodrug of 3′-Azido-2′,3′-dideoxythymidine (Zidovudine)
      Jan Balzarini, Lieve Naesens, S. Aquaro, T. Knispel, C.-F. Perno, E. De Clercq and C. Meier
      Molecular Pharmacology December 1999, 56 (6) 1354-1361; DOI: https://doi.org/10.1124/mol.56.6.1354

  2. Naganuma, Akira

    1. Protective Effects of Triterpene Compounds Against the Cytotoxicity of Cadmium in HepG2 Cells
      Nobuhiko Miura, Yoko Matsumoto, Shinichi Miyairi, Shoji Nishiyama and Akira Naganuma
      Molecular Pharmacology December 1999, 56 (6) 1324-1328; DOI: https://doi.org/10.1124/mol.56.6.1324

  3. Nahum-Levy, Rinat

    1. Putative Partial Agonist 1-Aminocyclopropanecarboxylic Acid Acts Concurrently as a Glycine-Site Agonist and a Glutamate-Site Antagonist at N-Methyl-d-aspartate Receptors
      Rinat Nahum-Levy, Linda H. Fossom, Phil Skolnick and Morris Benveniste
      Molecular Pharmacology December 1999, 56 (6) 1207-1218; DOI: https://doi.org/10.1124/mol.56.6.1207

  4. Niforatos, Wende

    1. Molecular and Functional Characterization of Human P2X2 Receptors
      Kevin J. Lynch, Edward Touma, Wende Niforatos, Karen L. Kage, Edward C. Burgard, Tim van Biesen, Elizabeth A. Kowaluk and Michael F. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1171-1181; DOI: https://doi.org/10.1124/mol.56.6.1171

  5. Nishiyama, Shoji

    1. Protective Effects of Triterpene Compounds Against the Cytotoxicity of Cadmium in HepG2 Cells
      Nobuhiko Miura, Yoko Matsumoto, Shinichi Miyairi, Shoji Nishiyama and Akira Naganuma
      Molecular Pharmacology December 1999, 56 (6) 1324-1328; DOI: https://doi.org/10.1124/mol.56.6.1324

  6. Northup, John K.

    1. Agonist Selective Regulation of G Proteins by Cannabinoid CB1 and CB2 Receptors
      Michelle Glass and John K. Northup
      Molecular Pharmacology December 1999, 56 (6) 1362-1369; DOI: https://doi.org/10.1124/mol.56.6.1362

O

  1. Ono, Mayumi

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

P

  1. Pannaccione, Anna

    1. Modulation of the K+ Channels Encoded by the Human Ether-a-Gogo-Related Gene-1 (hERG1) by Nitric Oxide
      Maurizio Taglialatela, Anna Pannaccione, Silvana Iossa, Pasqualina Castaldo and Lucio Annunziato
      Molecular Pharmacology December 1999, 56 (6) 1298-1308; DOI: https://doi.org/10.1124/mol.56.6.1298

  2. Perez, Dianne M.

    1. Cloning, Cell-Type Specificity, and Regulatory Function of the Mouse α1B-Adrenergic Receptor Promoter
      Michael J. Zuscik, Michael T. Piascik and Dianne M. Perez
      Molecular Pharmacology December 1999, 56 (6) 1288-1297; DOI: https://doi.org/10.1124/mol.56.6.1288

  3. Perno, C.-F.

    1. Intracellular Metabolism of CycloSaligenyl 3′-Azido-2′,3′-dideoxythymidine Monophosphate, a Prodrug of 3′-Azido-2′,3′-dideoxythymidine (Zidovudine)
      Jan Balzarini, Lieve Naesens, S. Aquaro, T. Knispel, C.-F. Perno, E. De Clercq and C. Meier
      Molecular Pharmacology December 1999, 56 (6) 1354-1361; DOI: https://doi.org/10.1124/mol.56.6.1354

  4. Piascik, Michael T.

    1. Cloning, Cell-Type Specificity, and Regulatory Function of the Mouse α1B-Adrenergic Receptor Promoter
      Michael J. Zuscik, Michael T. Piascik and Dianne M. Perez
      Molecular Pharmacology December 1999, 56 (6) 1288-1297; DOI: https://doi.org/10.1124/mol.56.6.1288

  5. Pollenz, Richard S.

    1. Analysis of Aryl Hydrocarbon Receptor-Mediated Signaling during Physiological Hypoxia Reveals Lack of Competition for the Aryl Hydrocarbon Nuclear Translocator Transcription Factor
      Richard S. Pollenz, Nikos A. Davarinos and Todd P. Shearer
      Molecular Pharmacology December 1999, 56 (6) 1127-1137; DOI: https://doi.org/10.1124/mol.56.6.1127

  6. Premkumar, Louis S.

    1. Selective Potentiation of L-Type Calcium Channel Currents by Cocaine in Cardiac Myocytes
      Louis S. Premkumar
      Molecular Pharmacology December 1999, 56 (6) 1138-1142; DOI: https://doi.org/10.1124/mol.56.6.1138

Q

  1. Qu, Yusheng

    1. Differential Interaction of R-Mexiletine with the Local Anesthetic Receptor Site on Brain and Heart Sodium Channel α-Subunits
      Thomas Weiser, Yusheng Qu, William A. Catterall and Todd Scheuer
      Molecular Pharmacology December 1999, 56 (6) 1238-1244; DOI: https://doi.org/10.1124/mol.56.6.1238

R

  1. Rees, Stephen

    1. Visualizing Differences in Ligand Regulation of Wild-Type and Constitutively Active Mutant β2-Adrenoceptor-Green Fluorescent Protein Fusion Proteins
      Alison J. McLean, Nicola Bevan, Stephen Rees and Graeme Milligan
      Molecular Pharmacology December 1999, 56 (6) 1182-1191; DOI: https://doi.org/10.1124/mol.56.6.1182

  2. Rivory, Laurent P.

    1. The Mechanism for the Inhibition of Acetylcholinesterases by Irinotecan (CPT-11)
      Helen M. Dodds and Laurent P. Rivory
      Molecular Pharmacology December 1999, 56 (6) 1346-1353; DOI: https://doi.org/10.1124/mol.56.6.1346

  3. Robberecht, Patrick

    1. Different Vasoactive Intestinal Polypeptide Receptor Domains Are Involved in the Selective Recognition of Two VPAC2-Selective Ligands
      Maria G. Juarranz, Jean Van Rampelbergh, Philippe Gourlet, Philippe De Neef, Johnny Cnudde, Patrick Robberecht and Magali Waelbroeck
      Molecular Pharmacology December 1999, 56 (6) 1280-1287; DOI: https://doi.org/10.1124/mol.56.6.1280

  4. Runge-Morris, Melissa

    1. Regulation of Rat Hepatic Hydroxysteroid Sulfotransferase (SULT2-40/41) Gene Expression by Glucocorticoids: Evidence for a Dual Mechanism of Transcriptional Control
      Melissa Runge-Morris, Wei Wu and Thomas A. Kocarek
      Molecular Pharmacology December 1999, 56 (6) 1198-1206; DOI: https://doi.org/10.1124/mol.56.6.1198

  5. Rybicki, Lisa A.

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

S

  1. Sakmar, Thomas P.

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  2. Scheuer, Todd

    1. Differential Interaction of R-Mexiletine with the Local Anesthetic Receptor Site on Brain and Heart Sodium Channel α-Subunits
      Thomas Weiser, Yusheng Qu, William A. Catterall and Todd Scheuer
      Molecular Pharmacology December 1999, 56 (6) 1238-1244; DOI: https://doi.org/10.1124/mol.56.6.1238

  3. Schwanstecher, Christina

    1. Stoichiometry of Potassium Channel Opener Action
      Insa Gross, Andreas Toman, Ingo Uhde, Christina Schwanstecher and Mathias Schwanstecher
      Molecular Pharmacology December 1999, 56 (6) 1370-1373; DOI: https://doi.org/10.1124/mol.56.6.1370

  4. Schwanstecher, Mathias

    1. Stoichiometry of Potassium Channel Opener Action
      Insa Gross, Andreas Toman, Ingo Uhde, Christina Schwanstecher and Mathias Schwanstecher
      Molecular Pharmacology December 1999, 56 (6) 1370-1373; DOI: https://doi.org/10.1124/mol.56.6.1370

  5. Seidenberg, Margaret

    1. Site-Directed Mutagenesis Reveals Two Epitopes Involved in the Subtype Selectivity of the Allosteric Interactions of Gallamine at Muscarinic Acetylcholine Receptors
      Ann L. Gnagey, Margaret Seidenberg and John Ellis
      Molecular Pharmacology December 1999, 56 (6) 1245-1253; DOI: https://doi.org/10.1124/mol.56.6.1245

  6. Sellar, Robin

    1. Pivotal Role for the Cytoplasmic Carboxyl-Terminal Tail of a Nonmammalian Gonadotropin-Releasing Hormone Receptor in Cell Surface Expression, Ligand Binding, and Receptor Phosphorylation and Internalization
      Marion Blomenröhr, Anders Heding, Robin Sellar, Rob Leurs, Jan Bogerd, Karin A. Eidne and Gary B. Willars
      Molecular Pharmacology December 1999, 56 (6) 1229-1237; DOI: https://doi.org/10.1124/mol.56.6.1229

  7. Shearer, Todd P.

    1. Analysis of Aryl Hydrocarbon Receptor-Mediated Signaling during Physiological Hypoxia Reveals Lack of Competition for the Aryl Hydrocarbon Nuclear Translocator Transcription Factor
      Richard S. Pollenz, Nikos A. Davarinos and Todd P. Shearer
      Molecular Pharmacology December 1999, 56 (6) 1127-1137; DOI: https://doi.org/10.1124/mol.56.6.1127

  8. Silvestri, Alessandra

    1. Domain Interactions Affecting Human DNA Topoisomerase I Catalysis and Camptothecin Sensitivity
      Paola Fiorani, James F. Amatruda, Alessandra Silvestri, Richard H. Butler, Mary-Ann Bjornsti and Piero Benedetti
      Molecular Pharmacology December 1999, 56 (6) 1105-1115; DOI: https://doi.org/10.1124/mol.56.6.1105

  9. Simpson, Merrill M.

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  10. Skolnick, Phil

    1. Putative Partial Agonist 1-Aminocyclopropanecarboxylic Acid Acts Concurrently as a Glycine-Site Agonist and a Glutamate-Site Antagonist at N-Methyl-d-aspartate Receptors
      Rinat Nahum-Levy, Linda H. Fossom, Phil Skolnick and Morris Benveniste
      Molecular Pharmacology December 1999, 56 (6) 1207-1218; DOI: https://doi.org/10.1124/mol.56.6.1207

  11. Snyder, Lenore A.

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  12. Suehiro, Makiko

    1. Dopamine D4/D2 Receptor Selectivity Is Determined by A Divergent Aromatic Microdomain Contained within the Second, Third, and Seventh Membrane-Spanning Segments
      Merrill M. Simpson, Juan A. Ballesteros, Victor Chiappa, Jiayun Chen, Makiko Suehiro, Deborah S. Hartman, Thierry Godel, Lenore A. Snyder, Thomas P. Sakmar and Jonathan A. Javitch
      Molecular Pharmacology December 1999, 56 (6) 1116-1126; DOI: https://doi.org/10.1124/mol.56.6.1116

  13. Sumizawa, Tomoyuki

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

T

  1. Taglialatela, Maurizio

    1. Modulation of the K+ Channels Encoded by the Human Ether-a-Gogo-Related Gene-1 (hERG1) by Nitric Oxide
      Maurizio Taglialatela, Anna Pannaccione, Silvana Iossa, Pasqualina Castaldo and Lucio Annunziato
      Molecular Pharmacology December 1999, 56 (6) 1298-1308; DOI: https://doi.org/10.1124/mol.56.6.1298

  2. Tan, Tse-Hua

    1. c-Jun N-Terminal Kinase Mediates Apoptotic Signaling Induced byN-(4-Hydroxyphenyl)retinamide
      Yi-Rong Chen, Guisheng Zhou and Tse-Hua Tan
      Molecular Pharmacology December 1999, 56 (6) 1271-1279; DOI: https://doi.org/10.1124/mol.56.6.1271

  3. Tilby, M. J.

    1. Murine Transgenic Cells Lacking DNA Topoisomerase IIβ Are Resistant to Acridines and Mitoxantrone: Analysis of Cytotoxicity and Cleavable Complex Formation
      F. Errington, E. Willmore, M. J. Tilby, L. Li, G. Li, W. Li, B. C. Baguley and C. A. Austin
      Molecular Pharmacology December 1999, 56 (6) 1309-1316; DOI: https://doi.org/10.1124/mol.56.6.1309

  4. Toman, Andreas

    1. Stoichiometry of Potassium Channel Opener Action
      Insa Gross, Andreas Toman, Ingo Uhde, Christina Schwanstecher and Mathias Schwanstecher
      Molecular Pharmacology December 1999, 56 (6) 1370-1373; DOI: https://doi.org/10.1124/mol.56.6.1370

  5. Touma, Edward

    1. Molecular and Functional Characterization of Human P2X2 Receptors
      Kevin J. Lynch, Edward Touma, Wende Niforatos, Karen L. Kage, Edward C. Burgard, Tim van Biesen, Elizabeth A. Kowaluk and Michael F. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1171-1181; DOI: https://doi.org/10.1124/mol.56.6.1171

U

  1. Uchiumi, Takeshi

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

  2. Uhde, Ingo

    1. Stoichiometry of Potassium Channel Opener Action
      Insa Gross, Andreas Toman, Ingo Uhde, Christina Schwanstecher and Mathias Schwanstecher
      Molecular Pharmacology December 1999, 56 (6) 1370-1373; DOI: https://doi.org/10.1124/mol.56.6.1370

V

  1. van Biesen, Tim

    1. Molecular and Functional Characterization of Human P2X2 Receptors
      Kevin J. Lynch, Edward Touma, Wende Niforatos, Karen L. Kage, Edward C. Burgard, Tim van Biesen, Elizabeth A. Kowaluk and Michael F. Jarvis
      Molecular Pharmacology December 1999, 56 (6) 1171-1181; DOI: https://doi.org/10.1124/mol.56.6.1171

  2. Van Rampelbergh, Jean

    1. Different Vasoactive Intestinal Polypeptide Receptor Domains Are Involved in the Selective Recognition of Two VPAC2-Selective Ligands
      Maria G. Juarranz, Jean Van Rampelbergh, Philippe Gourlet, Philippe De Neef, Johnny Cnudde, Patrick Robberecht and Magali Waelbroeck
      Molecular Pharmacology December 1999, 56 (6) 1280-1287; DOI: https://doi.org/10.1124/mol.56.6.1280

  3. Volk, Christopher

    1. Selectivity of the Polyspecific Cation Transporter rOCT1 Is Changed by Mutation of Aspartate 475 to Glutamate
      Valentin Gorboulev, Christopher Volk, Petra Arndt, Aida Akhoundova and Hermann Koepsell
      Molecular Pharmacology December 1999, 56 (6) 1254-1261; DOI: https://doi.org/10.1124/mol.56.6.1254

W

  1. Wada, Morimasa

    1. Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
      Zhe-Sheng Chen, Takeshi Kawabe, Mayumi Ono, Shunji Aoki, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Takeshi Uchiumi, Morimasa Wada, Michihiko Kuwano and Shin-Ichi Akiyama
      Molecular Pharmacology December 1999, 56 (6) 1219-1228; DOI: https://doi.org/10.1124/mol.56.6.1219

  2. Waelbroeck, Magali

    1. Different Vasoactive Intestinal Polypeptide Receptor Domains Are Involved in the Selective Recognition of Two VPAC2-Selective Ligands
      Maria G. Juarranz, Jean Van Rampelbergh, Philippe Gourlet, Philippe De Neef, Johnny Cnudde, Patrick Robberecht and Magali Waelbroeck
      Molecular Pharmacology December 1999, 56 (6) 1280-1287; DOI: https://doi.org/10.1124/mol.56.6.1280

  3. Weiser, Thomas

    1. Differential Interaction of R-Mexiletine with the Local Anesthetic Receptor Site on Brain and Heart Sodium Channel α-Subunits
      Thomas Weiser, Yusheng Qu, William A. Catterall and Todd Scheuer
      Molecular Pharmacology December 1999, 56 (6) 1238-1244; DOI: https://doi.org/10.1124/mol.56.6.1238

  4. Willars, Gary B.

    1. Pivotal Role for the Cytoplasmic Carboxyl-Terminal Tail of a Nonmammalian Gonadotropin-Releasing Hormone Receptor in Cell Surface Expression, Ligand Binding, and Receptor Phosphorylation and Internalization
      Marion Blomenröhr, Anders Heding, Robin Sellar, Rob Leurs, Jan Bogerd, Karin A. Eidne and Gary B. Willars
      Molecular Pharmacology December 1999, 56 (6) 1229-1237; DOI: https://doi.org/10.1124/mol.56.6.1229

  5. Willmore, E.

    1. Murine Transgenic Cells Lacking DNA Topoisomerase IIβ Are Resistant to Acridines and Mitoxantrone: Analysis of Cytotoxicity and Cleavable Complex Formation
      F. Errington, E. Willmore, M. J. Tilby, L. Li, G. Li, W. Li, B. C. Baguley and C. A. Austin
      Molecular Pharmacology December 1999, 56 (6) 1309-1316; DOI: https://doi.org/10.1124/mol.56.6.1309

  6. Wu, Wei

    1. Regulation of Rat Hepatic Hydroxysteroid Sulfotransferase (SULT2-40/41) Gene Expression by Glucocorticoids: Evidence for a Dual Mechanism of Transcriptional Control
      Melissa Runge-Morris, Wei Wu and Thomas A. Kocarek
      Molecular Pharmacology December 1999, 56 (6) 1198-1206; DOI: https://doi.org/10.1124/mol.56.6.1198

X

  1. Xin, Xiaohua

    1. Platelet-Derived Growth Factor Inhibits α1D-Adrenergic Receptor Expression in Vascular Smooth Muscle Cells In Vitro and Ex Vivo
      Xiaohua Xin, Nengyu Yang and James E. Faber
      Molecular Pharmacology December 1999, 56 (6) 1143-1151; DOI: https://doi.org/10.1124/mol.56.6.1143
    2. Platelet-Derived Growth Factor-BB Inhibits Rat α1D-Adrenergic Receptor Gene Expression in Vascular Smooth Muscle Cells by Inducing AP-2-Like Protein Binding to α1D Proximal Promoter Region
      Xiaohua Xin, Nengyu Yang and James E. Faber
      Molecular Pharmacology December 1999, 56 (6) 1152-1161; DOI: https://doi.org/10.1124/mol.56.6.1152

Y

  1. Yang, Nengyu

    1. Platelet-Derived Growth Factor Inhibits α1D-Adrenergic Receptor Expression in Vascular Smooth Muscle Cells In Vitro and Ex Vivo
      Xiaohua Xin, Nengyu Yang and James E. Faber
      Molecular Pharmacology December 1999, 56 (6) 1143-1151; DOI: https://doi.org/10.1124/mol.56.6.1143
    2. Platelet-Derived Growth Factor-BB Inhibits Rat α1D-Adrenergic Receptor Gene Expression in Vascular Smooth Muscle Cells by Inducing AP-2-Like Protein Binding to α1D Proximal Promoter Region
      Xiaohua Xin, Nengyu Yang and James E. Faber
      Molecular Pharmacology December 1999, 56 (6) 1152-1161; DOI: https://doi.org/10.1124/mol.56.6.1152

  2. Ye, Ying

    1. Altered Drug Interaction and Regulation of Topoisomerase IIβ: Potential Mechanisms Governing Sensitivity of HL-60 Cells to Amsacrine and Etoposide
      Dale R. Grabowski, Katherine A. Holmes, Masako Aoyama, Ying Ye, Lisa A. Rybicki, Ronald M. Bukowski, Mahrukh K. Ganapathi, Ian D. Hickson and Ram Ganapathi
      Molecular Pharmacology December 1999, 56 (6) 1340-1345; DOI: https://doi.org/10.1124/mol.56.6.1340

Z

  1. Zerangue, Noah

    1. Differentiation of Substrate and Nonsubstrate Inhibitors of the High-Affinity, Sodium-Dependent Glutamate Transporters
      Hans P. Koch, Michael P. Kavanaugh, Christopher S. Esslinger, Noah Zerangue, John M. Humphrey, Susan G. Amara, A. Richard Chamberlin and Richard J. Bridges
      Molecular Pharmacology December 1999, 56 (6) 1095-1104; DOI: https://doi.org/10.1124/mol.56.6.1095

  2. Zhou, Guisheng

    1. c-Jun N-Terminal Kinase Mediates Apoptotic Signaling Induced byN-(4-Hydroxyphenyl)retinamide
      Yi-Rong Chen, Guisheng Zhou and Tse-Hua Tan
      Molecular Pharmacology December 1999, 56 (6) 1271-1279; DOI: https://doi.org/10.1124/mol.56.6.1271

  3. Zuscik, Michael J.

    1. Cloning, Cell-Type Specificity, and Regulatory Function of the Mouse α1B-Adrenergic Receptor Promoter
      Michael J. Zuscik, Michael T. Piascik and Dianne M. Perez
      Molecular Pharmacology December 1999, 56 (6) 1288-1297; DOI: https://doi.org/10.1124/mol.56.6.1288
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