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Research ArticleArticle

The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module

Bryan Goodwin, Ecushla Hodgson and Christopher Liddle
Molecular Pharmacology December 1999, 56 (6) 1329-1339; DOI: https://doi.org/10.1124/mol.56.6.1329
Bryan Goodwin
Department of Clinical Pharmacology and Storr Liver Unit, University of Sydney at Westmead Hospital, Westmead, Australia
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Ecushla Hodgson
Department of Clinical Pharmacology and Storr Liver Unit, University of Sydney at Westmead Hospital, Westmead, Australia
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Christopher Liddle
Department of Clinical Pharmacology and Storr Liver Unit, University of Sydney at Westmead Hospital, Westmead, Australia
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Article Information

vol. 56 no. 6 1329-1339
DOI 
https://doi.org/10.1124/mol.56.6.1329
PubMed 
10570062

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received July 6, 1999
  • Accepted August 26, 1999
  • Published online December 1, 1999.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Bryan Goodwin,
  2. Ecushla Hodgson, and
  3. Christopher Liddle
  1. Department of Clinical Pharmacology and Storr Liver Unit, University of Sydney at Westmead Hospital, Westmead, Australia
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Molecular Pharmacology: 56 (6)
Molecular Pharmacology
Vol. 56, Issue 6
1 Dec 1999
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Research ArticleArticle

The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module

Bryan Goodwin, Ecushla Hodgson and Christopher Liddle
Molecular Pharmacology December 1, 1999, 56 (6) 1329-1339; DOI: https://doi.org/10.1124/mol.56.6.1329

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Research ArticleArticle

The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module

Bryan Goodwin, Ecushla Hodgson and Christopher Liddle
Molecular Pharmacology December 1, 1999, 56 (6) 1329-1339; DOI: https://doi.org/10.1124/mol.56.6.1329
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