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Molecular Pharmacology

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Table of Contents

January 01, 2000; Volume 57,Issue 1

Editorial

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    Editorial
    Joan Heller Brown
    Molecular Pharmacology January 2000, 57 (1) 1;

Articles

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    Reduced Apoptosis after Nerve Growth Factor and Serum Withdrawal: Conversion of Tetrameric Glyceraldehyde-3-Phosphate Dehydrogenase to a Dimer
    Graeme W. Carlile, Ruth M. E. Chalmers-Redman, Nadine A. Tatton, Amanda Pong, Katherine L.B. Borden and William G. Tatton
    Molecular Pharmacology January 2000, 57 (1) 2-12;
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    Incorporation of Gαz-Specific Sequence at the Carboxyl Terminus Increases the Promiscuity of Gα16toward Gi-Coupled Receptors
    Sejal M. Mody, Maurice K. C. Ho, Sushma A. Joshi and Yung H. Wong
    Molecular Pharmacology January 2000, 57 (1) 13-23;
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    Cloning and Expression of Murine Sister of P-Glycoprotein Reveals a More Discriminating Transporter ThanMDR1/P-Glycoprotein
    Valerie Lecureur, Daxi Sun, Philip Hargrove, Erin G. Schuetz, Richard B. Kim, Lu-Bin Lan and John D. Schuetz
    Molecular Pharmacology January 2000, 57 (1) 24-35;
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    Involvement of Protein Kinase C-γ in IL-1β-Induced Cyclooxygenase-2 Expression in Human Pulmonary Epithelial Cells
    Chien-Huang Lin, Sheng-Yuan Sheu, Horng-Mo Lee, Yuan-Soon Ho, Wen-Sen Lee, Wun-Chang Ko and Joen-Rong Sheu
    Molecular Pharmacology January 2000, 57 (1) 36-43;
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    Microtubule-Dependent Regulation of α2B Adrenergic Receptors in Polarized MDCKII Cells Requires the Third Intracellular Loop but Not G Protein Coupling
    Christine Saunders and Lee E. Limbird
    Molecular Pharmacology January 2000, 57 (1) 44-52;
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    Protein Kinase C ε Mediates Up-Regulation of N-Type Calcium Channels by Ethanol
    Thomas McMahon, Reid Andersen, Pamela Metten, John C. Crabbe and Robert O. Messing
    Molecular Pharmacology January 2000, 57 (1) 53-58;
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    Endothelin B Receptor-Mediated Regulation of ATP-Driven Drug Secretion in Renal Proximal Tubule
    Rosalinde Masereeuw, Sylvie A. Terlouw, Rémon A. M. H. van Aubel, Frans G. M. Russel and David S. Miller
    Molecular Pharmacology January 2000, 57 (1) 59-67;
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    Substrate Supply for Nitric-Oxide Synthase in Macrophages and Endothelial Cells: Role of Cationic Amino Acid Transporters
    Ellen I. Closs, Jan-Stefan Scheld, Masoumeh Sharafi and Ulrich Förstermann
    Molecular Pharmacology January 2000, 57 (1) 68-74;
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    Role of Heat Shock Protein 90 Dissociation in Mediating Agonist-Induced Activation of the Aryl Hydrocarbon Receptor
    Scott E. Heid, Richard S. Pollenz and Hollie I. Swanson
    Molecular Pharmacology January 2000, 57 (1) 82-92;
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    The Role of HNF-1α in Controlling Hepatic Catalase Activity
    Vijayakumar Muppala, Chun-Shien Lin and Ying-Hue Lee
    Molecular Pharmacology January 2000, 57 (1) 93-100;
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    Preferential Block of Late Sodium Current in the LQT3 ΔKPQ Mutant by the Class IC Antiarrhythmic Flecainide
    Toshihisa Nagatomo, Craig T. January and Jonathan C. Makielski
    Molecular Pharmacology January 2000, 57 (1) 101-107;
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    In Vivo Signal Transduction of Nociceptive Response by Kyotorphin (Tyrosine-Arginine) through Gαi- and Inositol Trisphosphate-Mediated Ca2+ Influx
    Hiroshi Ueda and Makoto Inoue
    Molecular Pharmacology January 2000, 57 (1) 108-115;
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    A Second Target for the Peptoid Tat/Transactivation Response Element Inhibitor CGP64222: Inhibition of Human Immunodeficiency Virus Replication by Blocking CXC-Chemokine Receptor 4-Mediated Virus Entry
    Dirk Daelemans, Dominique Schols, Myriam Witvrouw, Christophe Pannecouque, Sigrid Hatse, Sonia van Dooren, François Hamy, Thomas Klimkait, Erik de Clercq and Anne-Mieke VanDamme
    Molecular Pharmacology January 2000, 57 (1) 116-124;
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    Use of Constitutive G Protein-Coupled Receptor Activity for Drug Discovery
    Grace Chen, James Way, Susan Armour, Chris Watson, Ken Queen, Channa K. Jayawickreme, Wen-Ji Chen and Terry Kenakin
    Molecular Pharmacology January 2000, 57 (1) 125-134;
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    Inhibition of Na+ Current by Diphenhydramine and Other Diphenyl Compounds: Molecular Determinants of Selective Binding to the Inactivated Channels
    Chung-Chin Kuo, Ron-Chi Huang and Bih-Show Lou
    Molecular Pharmacology January 2000, 57 (1) 135-143;
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    Nonconserved Residues in the Second Transmembrane-Spanning Domain of the D4 Dopamine Receptor Are Molecular Determinants of D4-Selective Pharmacology
    John A. Schetz, Peter S. Benjamin and David R. Sibley
    Molecular Pharmacology January 2000, 57 (1) 144-152;
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    Essential Role of Mitogen-Activated Protein Kinase Pathway and c-Jun Induction in Epidermal Growth Factor-Induced Gene Expression of Human 12-Lipoxygenase
    Ben-Kuen Chen, Hui-Chung Kung, Tein-Yi Tsai and Wen-Chang Chang
    Molecular Pharmacology January 2000, 57 (1) 153-161;
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    The CB1 Cannabinoid Receptor Juxtamembrane C-Terminal Peptide Confers Activation to Specific G proteins in Brain
    Somnath Mukhopadhyay, Helen H. McIntosh, Devin B. Houston and Allyn C. Howlett
    Molecular Pharmacology January 2000, 57 (1) 162-170;
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    High-Affinity Binding of Peptide Agonists to the Human B1 Bradykinin Receptor Depends on Interaction between the Peptide N-Terminal l-Lysine and the Fourth Extracellular Domain of the Receptor
    Dana B. Fathy, Donald J. Kyle and L. M. Fredrik Leeb-Lundberg
    Molecular Pharmacology January 2000, 57 (1) 171-179;
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    Sustained Intracellular Retention of Dolastatin 10 Causes Its Potent Antimitotic Activity
    Pascal Verdier-Pinard, John A. Kepler, George R. Pettit and Ernest Hamel
    Molecular Pharmacology January 2000, 57 (1) 180-187;
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    Altered Expression of Hepatic Cytochromes P-450 in Mice Deficient in One or More mdr1 Genes
    Erin G. Schuetz, Diane R. Umbenhauer, Kazuto Yasuda, Cynthia Brimer, Lan Nguyen, Mary V. Relling, John D. Schuetz and Alfred H. Schinkel
    Molecular Pharmacology January 2000, 57 (1) 188-197;
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    Catechol-Binding Serines of β2-Adrenergic Receptors Control the Equilibrium between Active and Inactive Receptor States
    Caterina Ambrosio, Paola Molinari, Susanna Cotecchia and Tommaso Costa
    Molecular Pharmacology January 2000, 57 (1) 198-210;

Accelerated Communication

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    Possible Role of Valvular Serotonin 5-HT2B Receptors in the Cardiopathy Associated with Fenfluramine
    Lawrence W. Fitzgerald, Timothy C. Burn, Barry S. Brown, John P. Patterson, Martha H. Corjay, Patricia A. Valentine, Jung-Hui Sun, John R. Link, Ilgar Abbaszade, Jeannine M. Hollis, Brian L. Largent, Paul R. Hartig, Gregory F. Hollis, Paul C. Meunier, Albert J. Robichaud and David W. Robertson
    Molecular Pharmacology January 2000, 57 (1) 75-81;

CORRECTION

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    Molecular Pharmacology January 2000, 57 (1) 211;
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Molecular Pharmacology: 57 (1)
Molecular Pharmacology
Vol. 57, Issue 1
1 Jan 2000
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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