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Molecular Pharmacology

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Table of Contents

April 01, 2000; Volume 57,Issue 4

Editorial

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    Editorial
    Joan Heller Brown
    Molecular Pharmacology April 2000, 57 (4) 651; DOI: https://doi.org/10.1124/mol.57.4.651

MINIREVIEW

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    Protein Kinases as Mediators of Phosphoinositide 3-Kinase Signaling
    Alex Toker
    Molecular Pharmacology April 2000, 57 (4) 652-658; DOI: https://doi.org/10.1124/mol.57.4.652

Articles

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    Regulation of the Cellular Localization and Signaling Properties of the α1B- and α1D-Adrenoceptors by Agonists and Inverse Agonists
    Dan F. McCune, Stephanie E. Edelmann, Jennifer R. Olges, Ginell R. Post, Bruce A. Waldrop, David J. J. Waugh, Dianne M. Perez and Michael T. Piascik
    Molecular Pharmacology April 2000, 57 (4) 659-666; DOI: https://doi.org/10.1124/mol.57.4.659
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    Epidermal Growth Factor Receptor Agonists Increase Expression of Glutamate Transporter GLT-1 in Astrocytes through Pathways Dependent on Phosphatidylinositol 3-Kinase and Transcription Factor NF-κB
    Olga Zelenaia, Brian D. Schlag, Gordon E. Gochenauer, Raquelli Ganel, Wei Song, Jacqueline S. Beesley, Judith B. Grinspan, Jeffrey D. Rothstein and Michael B. Robinson
    Molecular Pharmacology April 2000, 57 (4) 667-678; DOI: https://doi.org/10.1124/mol.57.4.667
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    New Advances in the Transport of Doxorubicin through the Blood-Brain Barrier by a Peptide Vector-Mediated Strategy
    Christophe Rousselle, Philippe Clair, Jeanne-Marie Lefauconnier, Michel Kaczorek, Jean-Michel Scherrmann and Jamal Temsamani
    Molecular Pharmacology April 2000, 57 (4) 679-686; DOI: https://doi.org/10.1124/mol.57.4.679
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    Identification of Distinct Carboxyl-Terminal Domains Mediating Internalization and Down-Regulation of the Hamster α1B- Adrenergic Receptor
    Jiefa Wang, Lei Wang, Jialin Zheng, Jodi L. Anderson and Myron L. Toews
    Molecular Pharmacology April 2000, 57 (4) 687-694; DOI: https://doi.org/10.1124/mol.57.4.687
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    Interaction of Deoxyguanosine Nucleotide Analogs with Human Telomerase
    Susan W. Tendian and William B. Parker
    Molecular Pharmacology April 2000, 57 (4) 695-699; DOI: https://doi.org/10.1124/mol.57.4.695
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    Preactivation Permits Subsequent Stimulation of Phospholipase C by Gi-Coupled Receptors
    Joy S. C. Chan, Jonathan W. M. Lee, Maurice K. C. Ho and Yung H. Wong
    Molecular Pharmacology April 2000, 57 (4) 700-708; DOI: https://doi.org/10.1124/mol.57.4.700
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    Nitric Oxide Up-Regulates Aldose Reductase Expression in Rat Vascular Smooth Muscle Cells: A Potential Role for Aldose Reductase in Vascular Remodeling
    Han Geuk Seo, Toru Nishinaka and Chihiro Yabe-Nishimura
    Molecular Pharmacology April 2000, 57 (4) 709-717; DOI: https://doi.org/10.1124/mol.57.4.709
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    Hexapeptide and Cyclic Pentapeptide Endothelin Antagonists Directly Activate Pituitary Gonadotropin-Releasing Hormone Receptors
    Dror Yahalom, Yitzhak Koch, Nurit Ben-Aroya and Mati Fridkin
    Molecular Pharmacology April 2000, 57 (4) 718-724; DOI: https://doi.org/10.1124/mol.57.4.718
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    Antisense Inhibition of δ-Opioid Receptor Gene Function In Vivo by Peptide Nucleic Acids
    Graeme L. Fraser, Janna Holmgren, Paul B. S. Clarke and Claes Wahlestedt
    Molecular Pharmacology April 2000, 57 (4) 725-731; DOI: https://doi.org/10.1124/mol.57.4.725
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    Rifampicin Is Not an Activator of Glucocorticoid Receptor
    Alexandra S. Herr, Gabriele M. Wochnik, Marcus C. Rosenhagen, Florian Holsboer and Theo Rein
    Molecular Pharmacology April 2000, 57 (4) 732-737; DOI: https://doi.org/10.1124/mol.57.4.732
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    Differential Inhibition of Multiple cAMP Phosphodiesterase Isozymes by Isoflavones and Tyrphostins
    Michael R. Nichols and Bruce H. Morimoto
    Molecular Pharmacology April 2000, 57 (4) 738-745; DOI: https://doi.org/10.1124/mol.57.4.738
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    Differential Superactivation of Adenylyl Cyclase Isozymes after Chronic Activation of the CB1 Cannabinoid Receptor
    Man-Hee Rhee, Igal Nevo, Tomer Avidor-Reiss, Rivka Levy and Zvi Vogel
    Molecular Pharmacology April 2000, 57 (4) 746-752; DOI: https://doi.org/10.1124/mol.57.4.746
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    Molecular Cloning and Characterization of a Lysophosphatidic Acid Receptor, Edg-7, Expressed in Prostate
    Dong-Soon Im, Christopher E. Heise, Michael A. Harding, Susan R. George, Brian F. O'Dowd, Dan Theodorescu and Kevin R. Lynch
    Molecular Pharmacology April 2000, 57 (4) 753-759; DOI: https://doi.org/10.1124/mol.57.4.753
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    Interactions of the Human Multidrug Resistance Proteins MRP1 and MRP2 with Organic Anions
    Éva Bakos, Raymond Evers, Emese Sinkó, András Váradi, Piet Borst and Balázs Sarkadi
    Molecular Pharmacology April 2000, 57 (4) 760-768; DOI: https://doi.org/10.1124/mol.57.4.760
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    Loss of Cyclosporin and Azidopine Binding Are Associated with Altered ATPase Activity by a Mutant P-glycoprotein with Deleted Phe335
    Kevin G. Chen, Norman J. Lacayo, George E. Durán, Dalia Cohen and Branimir I. Sikic
    Molecular Pharmacology April 2000, 57 (4) 769-777; DOI: https://doi.org/10.1124/mol.57.4.769
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    Agonist-Dependent Modulation of G Protein-Coupled Receptor Kinase 2 by Mitogen-Activated Protein Kinases
    Ana Elorza, Susana Sarnago and Federico Mayor
    Molecular Pharmacology April 2000, 57 (4) 778-783; DOI: https://doi.org/10.1124/mol.57.4.778
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    Mutations at Arg486 and Glu571 in Human Topoisomerase IIα Confer Resistance to Amsacrine: Relevance for Antitumor Drug Resistance in Human Cells
    Sandhiya Patel, Beatrice A. Keller and L. Mark Fisher
    Molecular Pharmacology April 2000, 57 (4) 784-791; DOI: https://doi.org/10.1124/mol.57.4.784
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    Down-Regulation of Ceramide Production Abrogates Ionizing Radiation-Induced Cytochrome c Release and Apoptosis
    Steven J. Chmura, Edwardine Nodzenski, Surender Kharbanda, Pramod Pandey, Jose Quintans, Donald W. Kufe and Ralph R. Weichselbaum
    Molecular Pharmacology April 2000, 57 (4) 792-796; DOI: https://doi.org/10.1124/mol.57.4.792
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    Aspirin and Sodium Salicylate Inhibit Endothelin ETA Receptors by an Allosteric Type of Mechanism
    Anne Talbodec, Nathalie Berkane, Virginie Blandin, Jean Philippe Breittmayer, Emile Ferrari, Christian Frelin and Paul Vigne
    Molecular Pharmacology April 2000, 57 (4) 797-804; DOI: https://doi.org/10.1124/mol.57.4.797
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    A Molecularly Identified P2Y Receptor Simultaneously Activates Phospholipase C and Inhibits Adenylyl Cyclase and Is Nonselectively Activated by All Nucleoside Triphosphates
    José L. Boyer, Suzanne M. Delaney, Demetrio Villanueva and T. Kendall Harden
    Molecular Pharmacology April 2000, 57 (4) 805-810; DOI: https://doi.org/10.1124/mol.57.4.805
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    The Multifunctional Deoxynucleoside Kinase of Insect Cells Is a Target for the Development of New Insecticides
    Jan Balzarini, Bart Degrève, Sigrid Hatse, Erik De Clercq, Michael Breuer, Magnus Johansson, Roger Huybrechts and Anna Karlsson
    Molecular Pharmacology April 2000, 57 (4) 811-819; DOI: https://doi.org/10.1124/mol.57.4.811

Accelerated Communications

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    Alterations in Detergent Solubility of Heterotrimeric G Proteins after Chronic Activation of Gi/o-Coupled Receptors: Changes in Detergent Solubility Are in Correlation with Onset of Adenylyl Cyclase Superactivation
    Michael L. Bayewitch, Igal Nevo, Tomer Avidor-Reiss, Rivka Levy, William F. Simonds and Zvi Vogel
    Molecular Pharmacology April 2000, 57 (4) 820-825; DOI: https://doi.org/10.1124/mol.57.4.820
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    Selective Regulation of Gq Signaling by G Protein-Coupled Receptor Kinase 2: Direct Interaction of Kinase N Terminus with Activated Gαq
    Michele Sallese, Stefania Mariggiò, Etrusca D'Urbano, Luisa Iacovelli and Antonio De Blasi
    Molecular Pharmacology April 2000, 57 (4) 826-831; DOI: https://doi.org/10.1124/mol.57.4.826

Erratum

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    Molecular Pharmacology April 2000, 57 (4) 832; DOI: https://doi.org/10.1124/mol.57.4.832
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Molecular Pharmacology: 57 (4)
Molecular Pharmacology
Vol. 57, Issue 4
1 Apr 2000
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