Table of Contents

Articles

• You have access

  The Guanine Nucleotide Exchange Factor RasGRP Is a High -Affinity Target for Diacylglycerol and Phorbol Esters

  Patricia S. Lorenzo, Maryam Beheshti, George R. Pettit, James C. Stone and Peter M. Blumberg

  Molecular Pharmacology May 2000, 57 (5) 840-846;
• You have access

  Regulation of Recombinant γ-Aminobutyric Acid (GABA)_A and GABA_C Receptors by Protein Kinase C

  Natalia Filippova, Anna Sedelnikova, Yinong Zong, Henry Fortinberry and David S. Weiss

  Molecular Pharmacology May 2000, 57 (5) 847-856;
• You have access

  Up-Regulation of Airway Smooth Muscle Histamine H₁Receptor mRNA, Protein, and Function by β₂-Adrenoceptor Activation

  Judith C. W. Mak, Ad F. Roffel, Toshio Katsunuma, Carolina R. S. Elzinga, Johan Zaagsma and Peter J. Barnes

  Molecular Pharmacology May 2000, 57 (5) 857-864;
• You have access

  Stimulatory Effects of δ-Hexachlorocyclohexane on Ca²⁺-Activated K⁺ Currents in GH₃Lactotrophs

  Sheng-Nan Wu, Hui-Fang Li and Hung-Ting Chiang

  Molecular Pharmacology May 2000, 57 (5) 865-874;
• You have access

  Mutating the Highly Conserved Second Membrane-Spanning Region 9′ Leucine Residue in the α₁ or β₁ Subunit Produces Subunit-Specific Changes in the Function of Human α₁β₁ γ-Aminobutyric Acid_AReceptors

  Julie E. Dalziel, Graeme B. Cox, Peter W. Gage and Bryndis Birnir

  Molecular Pharmacology May 2000, 57 (5) 875-882;
• You have access

  Importance of Valine at Position 152 for the Substrate Transport and 2β-Carbomethoxy-3β-(4-fluorophenyl)tropane Binding of Dopamine Transporter

  Sang-Hun Lee, Mi-yoon Chang, Ki-Hwan Lee, Byung Sup Park, Young-Seek Lee, Hemin R. Chin and Yong-Sung Lee

  Molecular Pharmacology May 2000, 57 (5) 883-889;
• You have access

  The Effect of Mutations in the DRY Motif on the Constitutive Activity and Structural Instability of the Histamine H₂Receptor

  Astrid E. Alewijnse, Henk Timmerman, Edwin H. Jacobs, Martine J. Smit, Edwin Roovers, Susanna Cotecchia and Rob Leurs

  Molecular Pharmacology May 2000, 57 (5) 890-898;
• You have access

  Mechanism-Based Inactivation of Human Dihydropyrimidine Dehydrogenase by (E)-5-(2-Bromovinyl)uracil in the Presence of NADPH

  Takahito Nishiyama, Kenichiro Ogura, Haruhiro Okuda, Kazuma Suda, Atsushi Kato and Tadashi Watabe

  Molecular Pharmacology May 2000, 57 (5) 899-905;
• You have access

  The Neuroprotective Agent Riluzole Activates the Two P Domain K⁺ Channels TREK-1 and TRAAK

  Fabrice Duprat, Florian Lesage, Amanda J. Patel, Michel Fink, Georges Romey and Michel Lazdunski

  Molecular Pharmacology May 2000, 57 (5) 906-912;
• You have access

  ¹²⁵I-α-Conotoxin MII Identifies a Novel Nicotinic Acetylcholine Receptor Population in Mouse Brain

  Paul Whiteaker, J. Michael McIntosh, Siqin Luo, Allan C. Collins and Michael J. Marks

  Molecular Pharmacology May 2000, 57 (5) 913-925;
• You have access

  ATP, an Agonist at the Rat P2Y₄ Receptor, Is an Antagonist at the Human P2Y₄ Receptor

  Charles Kennedy, Ai-Dong Qi, Christopher L. Herold, T. Kendall Harden and Robert A. Nicholas

  Molecular Pharmacology May 2000, 57 (5) 926-931;
• You have access

  Identification of Benzodiazepine Binding Site Residues in the γ2 Subunit of the γ-Aminobutyric Acid_A Receptor

  Amy M. Kucken, David A. Wagner, Peter R. Ward, Jeremy A. Teissére, Andrew J. Boileau and Cynthia Czajkowski

  Molecular Pharmacology May 2000, 57 (5) 932-939;
• You have access

  Octamer Transcription Factor-1 Enhances Hepatic Nuclear Factor-1α-Mediated Activation of the Human UDP Glucuronosyltransferase 2B7 Promoter

  Yuji Ishii, Antony J. Hansen and Peter I. Mackenzie

  Molecular Pharmacology May 2000, 57 (5) 940-947;
• You have access

  The Mechanism of Phosphorylation of Anti-HIV D4T by Nucleoside Diphosphate Kinase

  Benoit Schneider, Ricardo Biondi, Robert Sarfati, Fabrice Agou, Catherine Guerreiro, Dominique Deville-Bonne and Michel Veron

  Molecular Pharmacology May 2000, 57 (5) 948-953;
• You have access

  Mutational Analysis of Trp-229 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase (RT) Identifies This Amino Acid Residue as a Prime Target for the Rational Design of New Non-Nucleoside RT Inhibitors

  Heidi Pelemans, Robert Esnouf, Erik De Clercq and Jan Balzarini

  Molecular Pharmacology May 2000, 57 (5) 954-960;
• You have access

  Activation of Signal Transducers and Activators of Transcription by α_1A-Adrenergic Receptor Stimulation in PC12 Cells

  Hongying Zhong, T. J. Murphy and Kenneth P. Minneman

  Molecular Pharmacology May 2000, 57 (5) 961-967;
• You have access

  [³H]MRE 3008F20: A Novel Antagonist Radioligand for the Pharmacological and Biochemical Characterization of Human A₃ Adenosine Receptors

  Katia Varani, Stefania Merighi, Stefania Gessi, Karl-Norbert Klotz, Edward Leung, Pier Giovanni Baraldi, Barbara Cacciari, Romeo Romagnoli, Giampiero Spalluto and Pier Andrea Borea

  Molecular Pharmacology May 2000, 57 (5) 968-975;
• You have access

  Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases

  Toshimasa Ishizaki, Masayoshi Uehata, Ichiro Tamechika, Jeongsin Keel, Kimiko Nonomura, Midori Maekawa and Shuh Narumiya

  Molecular Pharmacology May 2000, 57 (5) 976-983;
• You have access

  Role for Early Growth Response-1 Protein in α₁-Adrenergic Stimulation of Fibroblast Growth Factor-2 Promoter Activity in Cardiac Myocytes

  Yan Jin, Farah Sheikh, Karen A. Detillieux and Peter A. Cattini

  Molecular Pharmacology May 2000, 57 (5) 984-990;
• You have access

  Analysis of a Mutation in Phosphodiesterase Type 4 that Alters Both Inhibitor Activity and Nucleotide Selectivity

  Sarah B. Herman, Dawn M. Juilfs, Eric B. Fauman, Paul Juneau and Joseph P. Menetski

  Molecular Pharmacology May 2000, 57 (5) 991-999;
• You have access

  Activation of Cannabinoid Receptors in Rat Brain by WIN 55212-2 Produces Coupling to Multiple G Protein α-Subunits with Different Potencies

  Paul L. Prather, Nancy A. Martin, Christopher S. Breivogel and Steven R. Childers

  Molecular Pharmacology May 2000, 57 (5) 1000-1010;
• You have access

  Increased CYP2J Expression and Epoxyeicosatrienoic Acid Formation in Spontaneously Hypertensive Rat Kidney

  Zhigang Yu, Linn M. Huse, Peter Adler, LeRae Graham, Jixiang Ma, Darryl C. Zeldin and Deanna L. Kroetz

  Molecular Pharmacology May 2000, 57 (5) 1011-1020;
• You have access

  Inhibition of Aquaporin-1 Water Permeability by Tetraethylammonium: Involvement of the Loop E Pore Region

  Heddwen L. Brooks, John W. Regan and Andrea J. Yool

  Molecular Pharmacology May 2000, 57 (5) 1021-1026;
• You have access

  Lysophosphatidic Acid Modulates α_1b-Adrenoceptor Phosphorylation and Function: Roles of Gi and Phosphoinositide 3-Kinase

  Patricia Casas-González, José Vázquez-Prado and J. Adolfo García-Sáinz

  Molecular Pharmacology May 2000, 57 (5) 1027-1033;
• You have access

  Human 5-Hydroxytryptamine_5A Receptors Activate Coexpressed G_i and G_o Proteins inSpodoptera frugiperda 9 Cells

  Bart J. B. Francken, Katty Josson, Peter Lijnen, Mirek Jurzak, Walter H. M. L. Luyten and Josée E. Leysen

  Molecular Pharmacology May 2000, 57 (5) 1034-1044;
• You have access

  Endocannabinoid 2-Arachidonyl Glycerol Is a Full Agonist through Human Type 2 Cannabinoid Receptor: Antagonism by Anandamide

  Waldemar Gonsiorek, Charles Lunn, Xuedong Fan, Satwant Narula, Daniel Lundell and R. William Hipkin

  Molecular Pharmacology May 2000, 57 (5) 1045-1050;
• You have access

  Excision of β-d- and β-l-Nucleotide Analogs from DNA by the Human Cytosolic 3′-to-5′ Exonuclease

  Helene Pelicano, Marina Kukhanova and Yung-Chi Cheng

  Molecular Pharmacology May 2000, 57 (5) 1051-1055;
• You have access

  Altered Cell Cycle Control at the G₂/M Phases in Aryl Hydrocarbon Receptor-Null Embryo Fibroblast

  Guillermo Elizondo, Pedro Fernandez-Salguero, M. Saeed Sheikh, Geum-Yi Kim, Albert J. Fornace, Kyung S. Lee and Frank J. Gonzalez

  Molecular Pharmacology May 2000, 57 (5) 1056-1063;
• You have access

  Involvement of Regions in Domain I in the Opioid Receptor Sensitivity of α1B Ca²⁺ Channels

  Arthur A. Simen and Richard J. Miller

  Molecular Pharmacology May 2000, 57 (5) 1064-1074;