Mutating the Highly Conserved Second Membrane-Spanning Region 9′ Leucine Residue in the α1 or β1 Subunit Produces Subunit-Specific Changes in the Function of Human α1β1 γ-Aminobutyric AcidAReceptors

Julie E. Dalziel; Graeme B. Cox; Peter W. Gage; Bryndis Birnir

Article Information

vol. 57 no. 5 875-882

PubMed

10779369

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0026-895X

Online ISSN

1521-0111

History

Received October 27, 1999
Accepted February 3, 2000
Published online May 1, 2000.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

Julie E. Dalziel1,
Graeme B. Cox,
Peter W. Gage and
Bryndis Birnir2

Membrane Biology Program, John Curtin School of Medical Research, Australian National University, Canberra, Australian Capital Territory, Australia

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: April 2000 to October 2021

	Abstract	Full	Pdf
Apr 2000	25	6	30
May 2000	19	18	35
Jun 2000	6	13	10
Jul 2000	0	2	4
Aug 2000	3	3	3
Sep 2000	1	2	3
Oct 2000	1	3	7
Nov 2000	0	6	6
Dec 2000	0	5	1
Jan 2001	1	3	3
Feb 2001	1	2	1
Mar 2001	3	3	2
Apr 2001	2	5	5
May 2001	1	2	6
Jun 2001	0	1	3
Jul 2001	1	0	3
Aug 2001	1	4	4
Sep 2001	0	1	3
Oct 2001	0	1	1
Nov 2001	0	2	4
Dec 2001	0	6	5
Jan 2002	2	1	3
Feb 2002	0	1	5
Mar 2002	0	2	3
Apr 2002	1	3	4
May 2002	2	2	2
Jun 2002	0	1	1
Jul 2002	2	2	2
Aug 2002	1	0	3
Sep 2002	0	3	1
Oct 2002	0	8	5
Nov 2002	2	2	1
Dec 2002	1	2	3
Jan 2003	0	3	1
Feb 2003	1	3	6
Mar 2003	1	0	0
Apr 2003	0	3	2
May 2003	0	3	5
Jun 2003	3	4	2
Jul 2003	8	14	6
Aug 2003	8	11	5
Sep 2003	11	11	2
Oct 2003	9	13	4
Nov 2003	14	20	4
Dec 2003	16	15	5
Jan 2004	11	18	5
Feb 2004	15	12	4
Mar 2004	9	15	2
Apr 2004	6	11	6
May 2004	14	20	1
Jun 2004	11	21	1
Jul 2004	13	11	1
Aug 2004	7	10	1
Sep 2004	11	18	0
Oct 2004	14	21	2
Nov 2004	8	16	1
Dec 2004	6	21	1
Jan 2005	11	15	0
Feb 2005	11	12	1
Mar 2005	9	12	1
Apr 2005	2	11	4
May 2005	6	11	2
Jun 2005	19	16	0
Jul 2005	3	9	1
Aug 2005	6	9	0
Sep 2005	2	6	1
Oct 2005	5	8	3
Nov 2005	5	7	0
Dec 2005	4	9	2
Jan 2006	8	13	0
Feb 2006	8	14	1
Mar 2006	2	8	0
Apr 2006	2	5	2
May 2006	0	4	0
Jun 2006	0	6	0
Jul 2006	2	7	3
Sep 2006	0	2	0
Oct 2006	0	2	0
Nov 2006	1	7	0
Dec 2006	3	3	0
Jan 2007	2	11	0
Feb 2007	0	5	0
Mar 2007	2	3	2
Apr 2007	2	6	0
May 2007	3	7	0
Jun 2007	2	5	1
Jul 2007	1	3	1
Aug 2007	1	3	1
Sep 2007	0	5	2
Oct 2007	0	0	1
Nov 2007	3	3	3
Dec 2007	1	1	2
Jan 2008	1	1	0
Feb 2008	0	3	4
Mar 2008	3	3	3
Apr 2008	3	4	4
May 2008	1	3	1
Jun 2008	6	3	7
Jul 2008	3	1	2
Aug 2008	9	12	2
Sep 2008	8	10	2
Oct 2008	5	5	1
Nov 2008	5	7	6
Dec 2008	1	5	2
Jan 2009	2	4	0
Feb 2009	5	8	1
Mar 2009	6	9	2
Apr 2009	12	2	0
May 2009	5	10	3
Jun 2009	3	3	1
Jul 2009	3	5	0
Aug 2009	4	5	0
Sep 2009	7	4	1
Oct 2009	3	1	1
Nov 2009	4	3	1
Dec 2009	3	0	0
Jan 2010	4	1	3
Feb 2010	5	2	0
Mar 2010	4	1	1
Apr 2010	2	5	7
May 2010	5	3	2
Jun 2010	3	1	1
Jul 2010	1	1	0
Aug 2010	4	4	0
Sep 2010	4	2	4
Oct 2010	0	1	0
Nov 2010	6	3	6
Dec 2010	4	5	5
Jan 2011	6	5	2
Feb 2011	1	7	2
Mar 2011	3	4	8
Apr 2011	3	4	7
May 2011	5	1	2
Jun 2011	2	1	1
Jul 2011	3	1	7
Aug 2011	2	2	2
Sep 2011	6	8	9
Oct 2011	6	5	3
Nov 2011	8	8	6
Dec 2011	1	4	2
Jan 2012	5	2	3
Feb 2012	11	6	5
Mar 2012	8	2	2
Apr 2012	3	3	5
May 2012	11	3	8
Jun 2012	1	1	2
Jul 2012	4	2	5
Aug 2012	4	2	3
Sep 2012	3	2	1
Oct 2012	7	3	5
Nov 2012	4	2	3
Dec 2012	2	3	6
Jan 2013	3	5	5
Feb 2013	4	1	0
Mar 2013	0	4	1
Apr 2013	25	7	4
May 2013	7	3	5
Jun 2013	2	1	0
Jul 2013	3	1	0
Aug 2013	2	0	0
Sep 2013	4	0	0
Oct 2013	2	4	1
Nov 2013	1	1	1
Dec 2013	1	2	0
Jan 2014	6	1	3
Feb 2014	4	0	0
Mar 2014	0	4	3
Apr 2014	2	3	1
May 2014	3	3	3
Jun 2014	1	1	0
Jul 2014	5	1	3
Aug 2014	3	0	0
Sep 2014	3	4	5
Oct 2014	6	3	4
Nov 2014	9	2	5
Dec 2014	5	0	1
Jan 2015	8	1	3
Feb 2015	5	2	0
Mar 2015	3	0	4
Apr 2015	0	1	2
May 2015	5	0	2
Jun 2015	4	1	1
Jul 2015	3	12	10
Aug 2015	15	10	0
Sep 2015	5	3	5
Nov 2015	5	2	2
Dec 2015	2	2	2
Jan 2016	5	0	3
Feb 2016	9	3	4
Mar 2016	6	1	5
Apr 2016	1	0	7
May 2016	7	6	11
Jun 2016	1	0	5
Jul 2016	1	2	6
Aug 2016	1	5	2
Sep 2016	1	1	2
Oct 2016	0	7	2
Nov 2016	4	6	3
Dec 2016	0	2	1
Jan 2017	0	5	2
Feb 2017	0	4	2
Mar 2017	0	3	0
Apr 2017	0	3	3
May 2017	0	10	1
Jun 2017	0	4	1
Jul 2017	0	8	1
Aug 2017	0	9	0
Sep 2017	0	5	0
Oct 2017	0	6	0
Nov 2017	0	7	2
Dec 2017	0	5	0
Jan 2018	0	7	0
Feb 2018	0	6	6
Mar 2018	0	8	2
Apr 2018	0	13	2
May 2018	0	9	2
Jun 2018	0	4	4
Jul 2018	0	4	2
Aug 2018	0	1	0
Sep 2018	0	4	1
Oct 2018	0	8	1
Nov 2018	0	28	4
Dec 2018	17	3	0
Jan 2019	22	0	0
Feb 2019	16	0	0
Mar 2019	3	0	0
Apr 2019	3	0	0
May 2019	9	1	1
Jun 2019	2	0	2
Jul 2019	2	1	1
Aug 2019	5	2	0
Sep 2019	7	0	0
Oct 2019	5	0	0
Nov 2019	10	0	0
Dec 2019	4	0	0
Jan 2020	2	1	0
Feb 2020	5	0	0
Mar 2020	3	1	0
May 2020	2	2	0
Jun 2020	4	0	0
Jul 2020	7	0	1
Aug 2020	9	1	6
Sep 2020	5	0	0
Oct 2020	2	0	0
Nov 2020	6	1	0
Dec 2020	3	0	0
Jan 2021	4	1	0
Feb 2021	7	1	0
Mar 2021	7	1	0
Apr 2021	6	1	0
May 2021	25	1	0
Jun 2021	4	1	0
Jul 2021	4	1	1
Aug 2021	8	1	0
Sep 2021	1	1	0
Oct 2021	13	0	0