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Molecular Pharmacology

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Table of Contents

October 01, 2000; Volume 58,Issue 4

MINIREVIEW

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    Cell-Type Specific Integration of Cross-Talk between Extracellular Signal-Regulated Kinase and cAMP Signaling
    Miles D. Houslay and Walter Kolch
    Molecular Pharmacology October 2000, 58 (4) 659-668; DOI: https://doi.org/10.1124/mol.58.4.659

Articles

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    The Steroid 17α-Acetoxy-6-dimethylaminomethyl-21-fluoro-3-ethoxy-pregna-3,5-dien-20-one (SC17599) Is a Selective μ-Opioid Agonist: Implications for the μ-Opioid Pharmacophore
    Iain J. McFadyen, Hani Houshyar, Lee-Yuan Liu-Chen, James H. Woods and John R. Traynor
    Molecular Pharmacology October 2000, 58 (4) 669-676; DOI: https://doi.org/10.1124/mol.58.4.669
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    The Dopamine D3 Receptor Interacts with Itself and the Truncated D3 Splice Variant D3nf: D3-D3nf Interaction Causes Mislocalization of D3 Receptors
    Kelly D. Karpa, Ridwan Lin, Nadine Kabbani and Robert Levenson
    Molecular Pharmacology October 2000, 58 (4) 677-683; DOI: https://doi.org/10.1124/mol.58.4.677
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    A Single Amino Acid Mutation of Ala-773 in the Mineralocorticoid Receptor Confers Agonist Properties to 11β-Substituted Spirolactones
    Gilles Auzou, Jérôme Fagart, Anny Souque, Chantal Hellal-Lévy, Jean-Marie Wurtz, Dino Moras and Marie-Edith Rafestin-Oblin
    Molecular Pharmacology October 2000, 58 (4) 684-691; DOI: https://doi.org/10.1124/mol.58.4.684
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    An Analysis of the Variations in Potency of Grayanotoxin Analogs in Modifying Frog Sodium Channels of Differing Subtypes
    Masuhide Yakehiro, Tsunetsugu Yuki, Kaoru Yamaoka, Toshiaki Furue, Yasuo Mori, Keiji Imoto and Issei Seyama
    Molecular Pharmacology October 2000, 58 (4) 692-700; DOI: https://doi.org/10.1124/mol.58.4.692
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    Cyclosporin A Selectively Inhibits Mitogen-Induced Cyclooxygenase-2 Gene Transcription in Vascular Smooth Muscle Cells
    Aaron M. Robida, Kaiming Xu, Michelle L. Ellington and T. J. Murphy
    Molecular Pharmacology October 2000, 58 (4) 701-708; DOI: https://doi.org/10.1124/mol.58.4.701
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    Cellular Resistance to the Antitumor DNA Topoisomerase II Inhibitor S16020-2: Importance of the N-[2(Dimethylamino)ethyl]carbamoyl Side Chain
    Sandrine Le Mée, Françoise Chaminade, Charlotte Delaporte, Judith Markovits, Jean-Marie Saucier and Alain Jacquemin-Sablon
    Molecular Pharmacology October 2000, 58 (4) 709-718; DOI: https://doi.org/10.1124/mol.58.4.709
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    RGS3 Is a GTPase-Activating Protein for Giα and Gqα and a Potent Inhibitor of Signaling by GTPase-Deficient Forms of Gqα and G11α
    Astrid Scheschonka, Carmen W. Dessauer, Srikumar Sinnarajah, Peter Chidiac, Chong-Shan Shi and John H. Kehrl
    Molecular Pharmacology October 2000, 58 (4) 719-728; DOI: https://doi.org/10.1124/mol.58.4.719
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    Photo-Induced Inactivation of Protein Kinase Cα by Dequalinium Inhibits Motility of Murine Melanoma Cells
    Regina M. Sullivan, Michael Stone, John F. Marshall, Florian Uberall and Susan A. Rotenberg
    Molecular Pharmacology October 2000, 58 (4) 729-737; DOI: https://doi.org/10.1124/mol.58.4.729
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    Organic Vanadium Chelators Potentiate Vanadium-Evoked Glucose Metabolism In Vitro and In Vivo: Establishing Criteria for Optimal Chelators
    Itzhak Goldwaser, Sun Qian, Eytan Gershonov, Mati Fridkin and Yoram Shechter
    Molecular Pharmacology October 2000, 58 (4) 738-746; DOI: https://doi.org/10.1124/mol.58.4.738
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    Duplications and Defects in the CYP2A6 Gene: Identification, Genotyping, and In Vivo Effects on Smoking
    Yushu Rao, Ewa Hoffmann, Mohammad Zia, Laurent Bodin, Marilyn Zeman, Edward M. Sellers and Rachel F. Tyndale
    Molecular Pharmacology October 2000, 58 (4) 747-755; DOI: https://doi.org/10.1124/mol.58.4.747
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    Characterization of the Interaction of Zopiclone with γ-Aminobutyric Acid Type A Receptors
    Martin Davies, J. Glen Newell, Jason M. C. Derry, Ian L. Martin and Susan M. J. Dunn
    Molecular Pharmacology October 2000, 58 (4) 756-762; DOI: https://doi.org/10.1124/mol.58.4.756
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    Glycine Receptor β Subunits Play a Critical Role in Potentiation of Glycine Responses by ICS-205,930
    Stephane Supplisson and Dominique Chesnoy-Marchais
    Molecular Pharmacology October 2000, 58 (4) 763-770; DOI: https://doi.org/10.1124/mol.58.4.763
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    Adenosine A2A Receptors are Colocalized with and Activate Golf in Rat Striatum
    Björn Kull, Per Svenningsson and Bertil B. Fredholm
    Molecular Pharmacology October 2000, 58 (4) 771-777; DOI: https://doi.org/10.1124/mol.58.4.771
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    Rapid Relief of Block by Mecamylamine of Neuronal Nicotinic Acetylcholine Receptors of Rat Chromaffin Cells In Vitro: An Electrophysiological and Modeling Study
    Rashid A. Giniatullin, Elena M. Sokolova, Silvia Di Angelantonio, Andrei Skorinkin, Maria V. Talantova and Andrea Nistri
    Molecular Pharmacology October 2000, 58 (4) 778-787; DOI: https://doi.org/10.1124/mol.58.4.778
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    Structure-Activity Relationships for Growth Inhibition and Induction of Apoptosis by 4-Hydroxy-2-nonenal in Raw 264.7 Cells
    Robin L. Haynes, Luke Szweda, Kerry Pickin, Mark E. Welker and Alan J. Townsend
    Molecular Pharmacology October 2000, 58 (4) 788-794; DOI: https://doi.org/10.1124/mol.58.4.788
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    Mechanisms of Agonist-Induced Down-Regulation of the Human κ-Opioid Receptor: Internalization Is Required for Down-Regulation
    Jian-Guo Li, Jeffrey L. Benovic and Lee-Yuan Liu-Chen
    Molecular Pharmacology October 2000, 58 (4) 795-801; DOI: https://doi.org/10.1124/mol.58.4.795
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    Effects of the Potent Ampakine CX614 on Hippocampal and Recombinant AMPA Receptors: Interactions with Cyclothiazide and GYKI 52466
    Amy C. Arai, Markus Kessler, Gary Rogers and Gary Lynch
    Molecular Pharmacology October 2000, 58 (4) 802-813; DOI: https://doi.org/10.1124/mol.58.4.802
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    The CB1 Cannabinoid Receptor Is Coupled to the Activation of c-Jun N-Terminal Kinase
    Daniel Rueda, Ismael Galve-Roperh, Amador Haro and Manuel Guzmán
    Molecular Pharmacology October 2000, 58 (4) 814-820; DOI: https://doi.org/10.1124/mol.58.4.814
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    Transcriptional Down-Regulation of the Human α2C-Adrenergic Receptor by cAMP
    Stéphane Schaak, Cécile Cayla, Anastasios Lymperopoulos, Christodoulos Flordellis, Daniel Cussac, Colette Denis and Hervé Paris
    Molecular Pharmacology October 2000, 58 (4) 821-827; DOI: https://doi.org/10.1124/mol.58.4.821
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    Human Bradykinin B2 Receptor Is Activated by Kallikrein and Other Serine Proteases
    Claudie Hecquet, Fulong Tan, Branislav M. Marcic and Ervin G. Erdös
    Molecular Pharmacology October 2000, 58 (4) 828-836; DOI: https://doi.org/10.1124/mol.58.4.828
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    15-Deoxy-Δ12,14-prostaglandin J2Induces G1 Arrest and Differentiation Marker Expression in Vascular Smooth Muscle Cells
    Yoshikazu Miwa, Toshiyuki Sasaguri, Hiroyasu Inoue, Yoji Taba, Akio Ishida and Takeo Abumiya
    Molecular Pharmacology October 2000, 58 (4) 837-844; DOI: https://doi.org/10.1124/mol.58.4.837
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    Aryl Hydrocarbon Receptor Is Required for p300-Mediated Induction of DNA Synthesis by Adenovirus E1A
    Masahiro Tohkin, Morio Fukuhara, Guillermo Elizondo, Shuhei Tomita and Frank J. Gonzalez
    Molecular Pharmacology October 2000, 58 (4) 845-851; DOI: https://doi.org/10.1124/mol.58.4.845
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    Interaction of Methoxychlor and Related Compounds with Estrogen Receptor α and β, and Androgen Receptor: Structure-Activity Studies
    Kevin W. Gaido, Susan C. Maness, Donald P. McDonnell, Shangara S. Dehal, David Kupfer and Stephen Safe
    Molecular Pharmacology October 2000, 58 (4) 852-858; DOI: https://doi.org/10.1124/mol.58.4.852

Accelerated Communications

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    RNA Editing of the Human Serotonin 5-HT2C Receptor Delays Agonist-Stimulated Calcium Release
    Raymond D. Price and Elaine Sanders-Bush
    Molecular Pharmacology October 2000, 58 (4) 859-862; DOI: https://doi.org/10.1124/mol.58.4.859
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    Mdr1 Limits CYP3A Metabolism in Vivo
    Lu-Bin Lan, James T. Dalton and Erin G. Schuetz
    Molecular Pharmacology October 2000, 58 (4) 863-869; DOI: https://doi.org/10.1124/mol.58.4.863
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    Identification of a Human Gastrointestinal Tract and Immune System Receptor for the Peptide Neuromedin U
    Joseph A. Hedrick, Kelley Morse, LiXin Shan, Xudong Qiao, Ling Pang, Suke Wang, Thomas Laz, Eric L. Gustafson, Marvin Bayne and Frederick J. Monsma
    Molecular Pharmacology October 2000, 58 (4) 870-875; DOI: https://doi.org/10.1124/mol.58.4.870
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Molecular Pharmacology: 58 (4)
Molecular Pharmacology
Vol. 58, Issue 4
1 Oct 2000
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  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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