Table of Contents

Articles

• You have access

  Differential Modes of Agonist Binding to 5-Hydroxytryptamine_2A Serotonin Receptors Revealed by Mutation and Molecular Modeling of Conserved Residues in Transmembrane Region 5

  David A. Shapiro, Kurt Kristiansen, Wesley K. Kroeze and Bryan L. Roth

  Molecular Pharmacology November 2000, 58 (5) 877-886; DOI: https://doi.org/10.1124/mol.58.5.877
• You have access

  Spontaneous Activation of β₂- but Not β₁-Adrenoceptors Expressed in Cardiac Myocytes from β₁β₂ Double Knockout Mice

  Ying-Ying Zhou, Dongmei Yang, Wei-Zhong Zhu, Sheng-Jun Zhang, Ding-Ji Wang, Dan K. Rohrer, Eric Devic, Brian K. Kobilka, Edward G. Lakatta, Heping Cheng and Rui-Ping Xiao

  Molecular Pharmacology November 2000, 58 (5) 887-894; DOI: https://doi.org/10.1124/mol.58.5.887
• You have access

  Functional Comparisons of the Lysophosphatidic Acid Receptors, LP_A1/VZG-1/EDG-2, LP_A2/EDG-4, and LP_A3/EDG-7 in Neuronal Cell Lines Using a Retrovirus Expression System

  Isao Ishii, James J. A. Contos, Nobuyuki Fukushima and Jerold Chun

  Molecular Pharmacology November 2000, 58 (5) 895-902; DOI: https://doi.org/10.1124/mol.58.5.895
• You have access

  Cyclic AMP and Protein Kinase A Stimulate Cdc42: Role of A₂ Adenosine Receptors in Human Mast Cells

  Igor Feoktistov, Anna E. Goldstein and Italo Biaggioni

  Molecular Pharmacology November 2000, 58 (5) 903-910; DOI: https://doi.org/10.1124/mol.58.5.903
• You have access

  Structural Insights into the Amino-Terminus of the Secretin Receptor: I. Status of Cysteine and Cystine Residues

  Yan W. Asmann, Maoqing Dong, Subhas Ganguli, Elizabeth M. Hadac and Laurence J. Miller

  Molecular Pharmacology November 2000, 58 (5) 911-919; DOI: https://doi.org/10.1124/mol.58.5.911
• You have access

  Oxaliplatin-Induced Damage of Cellular DNA

  Jan M. Woynarowski, Sandrine Faivre, Maryanne C.S. Herzig, Brenda Arnett, William G. Chapman, Alex V. Trevino, Eric Raymond, Stephen G. Chaney, Alexandra Vaisman, Maria Varchenko and Paul E. Juniewicz

  Molecular Pharmacology November 2000, 58 (5) 920-927; DOI: https://doi.org/10.1124/mol.58.5.920
• You have access

  Cyclosaligenyl-2′,3′-didehydro-2′,3′-dideoxythymidine Monophosphate: Efficient Intracellular Delivery of d4TMP

  Jan Balzarini, Stefano Aquaro, Tina Knispel, Chiara Rampazzo, Vera Bianchi, Carlo-Federico Perno, Erik De Clercq and Chris Meier

  Molecular Pharmacology November 2000, 58 (5) 928-935; DOI: https://doi.org/10.1124/mol.58.5.928
• You have access

  Characterization of Calcium Signaling by Purinergic Receptor-Channels Expressed in Excitable Cells

  Taka-aki Koshimizu, Fredrick Van Goor, Melanija Tomić, Anderson On-Lam Wong, Akito Tanoue, Gozoh Tsujimoto and Stanko S. Stojilkovic

  Molecular Pharmacology November 2000, 58 (5) 936-945; DOI: https://doi.org/10.1124/mol.58.5.936
• You have access

  Evidence That Gα_q-Coupled Receptor-Induced Interleukin-6 mRNA in Vascular Smooth Muscle Cells Involves the Nuclear Factor of Activated T Cells

  Karen L. Abbott, James R. Loss, Aaron M. Robida and T. J. Murphy

  Molecular Pharmacology November 2000, 58 (5) 946-953; DOI: https://doi.org/10.1124/mol.58.5.946
• You have access

  Molecular Analysis of β₂-Adrenoceptor Coupling to G_s-, G_i-, and G_q-Proteins

  Katharina Wenzel-Seifert and Roland Seifert

  Molecular Pharmacology November 2000, 58 (5) 954-966; DOI: https://doi.org/10.1124/mol.58.5.954
• You have access

  Structure-Related Inhibition of Calmodulin-Dependent Neuronal Nitric-Oxide Synthase Activity by Melatonin and Synthetic Kynurenines

  Josefa León, Manuel Macías, Germaine Escames, Encarna Camacho, Huda Khaldy, Miguel Martín, Antonio Espinosa, Miguel A. Gallo and Darío Acuña-Castroviejo

  Molecular Pharmacology November 2000, 58 (5) 967-975; DOI: https://doi.org/10.1124/mol.58.5.967
• You have access

  Fibronectin-Mediated Hepatocyte Shape Change Reprograms Cytochrome P450 2C11 Gene Expression via an Integrin-Signaled Induction of Ribonuclease Activity

  Conrad P. Hodgkinson, Matthew C. Wright and Alan J. Paine

  Molecular Pharmacology November 2000, 58 (5) 976-981; DOI: https://doi.org/10.1124/mol.58.5.976
• You have access

  Analysis of the Interaction between the HIV-Inactivating Protein Cyanovirin-N and Soluble Forms of the Envelope Glycoproteins gp120 and gp41

  Barry R. O'Keefe, Shilpa R. Shenoy, Dong Xie, Wentao Zhang, Jeffrey M. Muschik, Michael J. Currens, Irwin Chaiken and Michael R. Boyd

  Molecular Pharmacology November 2000, 58 (5) 982-992; DOI: https://doi.org/10.1124/mol.58.5.982
• You have access

  The Amino Terminus of Gα_z is Required for Receptor Recognition, Whereas its α4/β6 Loop Is Essential for Inhibition of Adenylyl Cyclase

  Maurice K.C. Ho and Yung H. Wong

  Molecular Pharmacology November 2000, 58 (5) 993-1000; DOI: https://doi.org/10.1124/mol.58.5.993
• You have access

  G₁ Phase-Dependent Expression of Bcl-2 mRNA and Protein Correlates with Chemoresistance of Human Cancer Cells

  Gui Gao and Q. Ping Dou

  Molecular Pharmacology November 2000, 58 (5) 1001-1010; DOI: https://doi.org/10.1124/mol.58.5.1001
• You have access

  Overexpression of Type 7 Adenylyl Cyclase in the Mouse Brain Enhances Acute and Chronic Actions of Morphine

  Masami Yoshimura, Peter H. Wu, Paula L. Hoffman and Boris Tabakoff

  Molecular Pharmacology November 2000, 58 (5) 1011-1016; DOI: https://doi.org/10.1124/mol.58.5.1011
• You have access

  The Essential Role of Phosphatidylinositol 3-Kinase and of p38 Mitogen-Activated Protein Kinase Activation in the Antioxidant Response Element-Mediated rGSTA2 Induction by Decreased Glutathione in H4IIE Hepatoma Cells

  Keon Wook Kang, Ji Hwa Ryu and Sang Geon Kim

  Molecular Pharmacology November 2000, 58 (5) 1017-1025; DOI: https://doi.org/10.1124/mol.58.5.1017
• You have access

  The Inhibitory Potency and Selectivity of Arginine Substrate Site Nitric-Oxide Synthase Inhibitors Is Solely Determined by Their Affinity toward the Different Isoenzymes

  Rainer Boer, Wolf-Rüdiger Ulrich, Thomas Klein, Berit Mirau, Sabine Haas and Ilka Baur

  Molecular Pharmacology November 2000, 58 (5) 1026-1034; DOI: https://doi.org/10.1124/mol.58.5.1026
• You have access

  Creation of a Selective Antagonist and Agonist of the Rat VPAC₁ Receptor Using a Combinatorial Approach with Vasoactive Intestinal Peptide 6–23 as Template

  Jeppe Wegener Tams, Rikke Malene Jørgensen, Arne Holm and Jan Fahrenkrug

  Molecular Pharmacology November 2000, 58 (5) 1035-1041; DOI: https://doi.org/10.1124/mol.58.5.1035
• You have access

  Inverse Agonism and Constitutive Activity as Functional Correlates of Serotonin h5-HT_1B Receptor/G-Protein Stoichiometry

  Adrian Newman-Tancredi, Valérie Audinot, Celia Moreira, Laurence Verrièle and Mark J. Millan

  Molecular Pharmacology November 2000, 58 (5) 1042-1049; DOI: https://doi.org/10.1124/mol.58.5.1042
• You have access

  Identification of G Protein-Coupled Receptor Kinase 2 Phosphorylation Sites Responsible for Agonist-Stimulated δ-Opioid Receptor Phosphorylation

  Jun Guo, Yalan Wu, Wenbo Zhang, Jing Zhao, Lakshmi A. Devi, Gang Pei and Lan Ma

  Molecular Pharmacology November 2000, 58 (5) 1050-1056; DOI: https://doi.org/10.1124/mol.58.5.1050
• You have access

  Regulation of Cell Proliferation, Gene Expression, Production of Cytokines, and Cell Cycle Progression in Primary Human T Lymphocytes by Piperlactam S Isolated from Piper kadsura

  Yuh-Chi Kuo, Nai-Shian Yang, Cheng-Jen Chou, Lie-Chwen Lin and Wei-Jern Tsai

  Molecular Pharmacology November 2000, 58 (5) 1057-1066; DOI: https://doi.org/10.1124/mol.58.5.1057
• You have access

  Structure Activity Relationship of Carboxylic Ester Antagonists of the Vitamin D₃ Receptor

  Yvonne Bury, Andreas Steinmeyer and Carsten Carlberg

  Molecular Pharmacology November 2000, 58 (5) 1067-1074; DOI: https://doi.org/10.1124/mol.58.5.1067
• You have access

  Influence of Receptor Number on Functional Responses Elicited by Agonists Acting at the Human Adenosine A₁ Receptor: Evidence for Signaling Pathway-Dependent Changes in Agonist Potency and Relative Intrinsic Activity

  Yolande Cordeaux, Stephen J. Briddon, Anne E. Megson, Jacqui McDonnell, John M. Dickenson and Stephen J. Hill

  Molecular Pharmacology November 2000, 58 (5) 1075-1084; DOI: https://doi.org/10.1124/mol.58.5.1075
• You have access

  Analysis of the Pharmacological and Molecular Heterogeneity of I₂-Imidazoline-Binding Proteins using Monoamine Oxidase-Deficient Mouse Models

  Anne Remaury, Rita Raddatz, Catherine Ordener, Sandra Savic, Jean C. Shih, Kevin Chen, Isabelle Seif, Edward De Maeyer, Stephen M. Lanier and Angelo Parini

  Molecular Pharmacology November 2000, 58 (5) 1085-1090; DOI: https://doi.org/10.1124/mol.58.5.1085
• You have access

  Agonist Binding and Function at the Human α_2A-Adrenoceptor: Allosteric Modulation by Amilorides

  Ray A. Leppik and Nigel J. M. Birdsall

  Molecular Pharmacology November 2000, 58 (5) 1091-1099; DOI: https://doi.org/10.1124/mol.58.5.1091
• You have access

  Polyanionic (i.e., Polysulfonate) Dendrimers Can Inhibit the Replication of Human Immunodeficiency Virus by Interfering with Both Virus Adsorption and Later Steps (Reverse Transcriptase/Integrase) in the Virus Replicative Cycle

  Myriam Witvrouw, Valery Fikkert, Wim Pluymers, Barry Matthews, Karen Mardel, Dominique Schols, John Raff, Zeger Debyser, Erik De Clercq, George Holan and Christophe Pannecouque

  Molecular Pharmacology November 2000, 58 (5) 1100-1108; DOI: https://doi.org/10.1124/mol.58.5.1100
• You have access

  Metabolism and Mode of Inhibition of Varicella-Zoster Virus byl-β-5-Bromovinyl-(2-hydroxymethyl)-(1,3-dioxolanyl)uracil Is Dependent on Viral Thymidine Kinase

  Ling Li, Ginger E. Dutschman, Elizabeth A. Gullen, Eisaku Tsujii, Susan P. Grill, Yongseok Choi, Chung K. Chu and Yung-chi Cheng

  Molecular Pharmacology November 2000, 58 (5) 1109-1114; DOI: https://doi.org/10.1124/mol.58.5.1109
• You have access

  Pharmacological Blockade of ERG K⁺ Channels and Ca²⁺ Influx through Store-Operated Channels Exerts Opposite Effects on Intracellular Ca²⁺ Oscillations in Pituitary GH₃ Cells

  Agnese Secondo, Maurizio Taglialatela, Mauro Cataldi, Giovanna Giorgio, Monica Valore, Gianfranco Di Renzo and Lucio Annunziato

  Molecular Pharmacology November 2000, 58 (5) 1115-1128; DOI: https://doi.org/10.1124/mol.58.5.1115
• You have access

  Benzodiazepines Induce a Conformational Change in the Region of the γ-Aminobutyric Acid Type A Receptor α₁-Subunit M3 Membrane-Spanning Segment

  Daniel B. Williams and Myles H. Akabas

  Molecular Pharmacology November 2000, 58 (5) 1129-1136; DOI: https://doi.org/10.1124/mol.58.5.1129
• You have access

  Sodium Dodecyl Sulfate-Stable Complexes of Echistatin and RGD-Dependent Integrins: A Novel Approach to Study Integrins

  Gaétan Thibault

  Molecular Pharmacology November 2000, 58 (5) 1137-1145; DOI: https://doi.org/10.1124/mol.58.5.1137
• You have access

  Establishment of an Isogenic Human Colon Tumor Model forNQO1 Gene Expression: Application to Investigate the Role of DT-Diaphorase in Bioreductive Drug Activation In Vitro and In Vivo

  Swee Y. Sharp, Lloyd R. Kelland, Melanie R. Valenti, Lisa A. Brunton, Steve Hobbs and Paul Workman

  Molecular Pharmacology November 2000, 58 (5) 1146-1155; DOI: https://doi.org/10.1124/mol.58.5.1146