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Molecular Pharmacology

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Table of Contents

March 01, 2001; Volume 59,Issue 3

MINIREVIEW

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    Genetic Multiplicity of the Human UDP-Glucuronosyltransferases and Regulation in the Gastrointestinal Tract
    Robert H. Tukey and Christian P. Strassburg
    Molecular Pharmacology March 2001, 59 (3) 405-414; DOI: https://doi.org/10.1124/mol.59.3.405

Perspective

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    Genomics Meets Histamine Receptors: New Subtypes, New Receptors
    Lindsay B. Hough
    Molecular Pharmacology March 2001, 59 (3) 415-419; DOI: https://doi.org/10.1124/mol.59.3.415

Accelerated Communications

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    Cloning and Pharmacological Characterization of a Fourth Histamine Receptor (H4) Expressed in Bone Marrow
    Changlu Liu, Xiao-Jun Ma, Xiaoxia Jiang, Sandy J. Wilson, Claudia L. Hofstra, Jonathan Blevitt, Jayashree Pyati, Xiaobing Li, Wenying Chai, Nicholas Carruthers and Timothy W. Lovenberg
    Molecular Pharmacology March 2001, 59 (3) 420-426; DOI: https://doi.org/10.1124/mol.59.3.420
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    Discovery of a Novel Member of the Histamine Receptor Family
    Tuan Nguyen, David A. Shapiro, Susan R. George, Vincent Setola, Dennis K. Lee, Regina Cheng, Laura Rauser, Samuel P. Lee, Kevin R. Lynch, Bryan L. Roth and Brian F. O'Dowd
    Molecular Pharmacology March 2001, 59 (3) 427-433; DOI: https://doi.org/10.1124/mol.59.3.427
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    Cloning, Expression, and Pharmacological Characterization of a Novel Human Histamine Receptor
    Yuan Zhu, David Michalovich, Hsiao-Ling Wu, K. B. Tan, George M. Dytko, Ishrat J. Mannan, Rogely Boyce, James Alston, Lauren A Tierney, Xiaotong Li, Nicole C. Herrity, Lisa Vawter, Henry M. Sarau, Robert S. Ames, Colleen M. Davenport, J. Paul Hieble, Shelagh Wilson, Derk J. Bergsma and Laura R. Fitzgerald
    Molecular Pharmacology March 2001, 59 (3) 434-441; DOI: https://doi.org/10.1124/mol.59.3.434
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    Molecular Targets for the Myorelaxant Action of Diazepam
    Florence Crestani, Karin Löw, Ruth Keist, Marie-Juliette Mandelli, Hanns Möhler and Uwe Rudolph
    Molecular Pharmacology March 2001, 59 (3) 442-445; DOI: https://doi.org/10.1124/mol.59.3.442

Articles

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    A Novel Approach to Thymidylate Synthase as a Target for Cancer Chemotherapy
    Qing Li, Christopher Boyer, Jean Y. Lee and H. Michael Shepard
    Molecular Pharmacology March 2001, 59 (3) 446-452; DOI: https://doi.org/10.1124/mol.59.3.446
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    The Catalytic DNA Topoisomerase II Inhibitor Dexrazoxane (ICRF-187) Induces Differentiation and Apoptosis in Human Leukemia K562 Cells
    Brian B. Hasinoff, Michael E. Abram, Norman Barnabé, Tayeb Khélifa, William P. Allan and Jack C. Yalowich
    Molecular Pharmacology March 2001, 59 (3) 453-461; DOI: https://doi.org/10.1124/mol.59.3.453
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    Dolastatin 11, a Marine Depsipeptide, Arrests Cells at Cytokinesis and Induces Hyperpolymerization of Purified Actin
    Ruoli Bai, Pascal Verdier-Pinard, Sanjeev Gangwar, Chad C. Stessman, Kelly J. McClure, Edward A. Sausville, George R. Pettit, Robert B. Bates and Ernest Hamel
    Molecular Pharmacology March 2001, 59 (3) 462-469; DOI: https://doi.org/10.1124/mol.59.3.462
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    Two Nuclear Proteins, Cin5 and Ydr259c, Confer Resistance to Cisplatin in Saccharomyces cerevisiae
    Takemitsu Furuchi, Hirohide Ishikawa, Nobuhiko Miura, Miki Ishizuka, Kazuki Kajiya, Shusuke Kuge and Akira Naganuma
    Molecular Pharmacology March 2001, 59 (3) 470-474; DOI: https://doi.org/10.1124/mol.59.3.470
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    Amino Acid Residues Critical for Differential Inhibition of CYP2B4, CYP2B5, and CYP2B1 by Phenylimidazoles
    Margit Spatzenegger, Qinmi Wang, You Qun He, Michael R. Wester, Eric F. Johnson and James R. Halpert
    Molecular Pharmacology March 2001, 59 (3) 475-484; DOI: https://doi.org/10.1124/mol.59.3.475
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    Inhibition of Corticotropin Releasing Hormone Type-1 Receptor Translation by an Upstream AUG Triplet in the 5′ Untranslated Region
    Guoheng Xu, Cristina Rabadan-Diehl, Maria Nikodemova, Peter Wynn, Joachim Spiess and Greti Aguilera
    Molecular Pharmacology March 2001, 59 (3) 485-492; DOI: https://doi.org/10.1124/mol.59.3.485
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    Tumor Necrosis Factor-α-Induced Cyclooxygenase-2 Expression via Sequential Activation of Ceramide-Dependent Mitogen-Activated Protein Kinases, and IκB Kinase 1/2 in Human Alveolar Epithelial Cells
    Ching-Chow Chen, Yi-Tao Sun, Jun-Jie Chen and Ya-Jen Chang
    Molecular Pharmacology March 2001, 59 (3) 493-500; DOI: https://doi.org/10.1124/mol.59.3.493
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    A Typical Y1 Receptor Regulates Feeding Behaviors: Effects of a Potent and Selective Y1 Antagonist, J-115814
    Akio Kanatani, Mikiko Hata, Satoshi Mashiko, Akane Ishihara, Osamu Okamoto, Yuji Haga, Tomoyuki Ohe, Tetsuya Kanno, Naomi Murai, Yasuyuki Ishii, Takahiro Fukuroda, Takehiro Fukami and Masaki Ihara
    Molecular Pharmacology March 2001, 59 (3) 501-505; DOI: https://doi.org/10.1124/mol.59.3.501
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    A Bioactive Metabolite of Benzo[a]pyrene, Benzo[a]pyrene-7,8-dione, Selectively Alters Microsomal Ca2+ Transport and Ryanodine Receptor Function
    Isaac N. Pessah, Chris Beltzner, Scott W. Burchiel, Gopishetty Sridhar, Trevor Penning and Wei Feng
    Molecular Pharmacology March 2001, 59 (3) 506-513; DOI: https://doi.org/10.1124/mol.59.3.506
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    Interactions of Tryptamine Derivatives with Serotonin Transporter Species Variants Implicate Transmembrane Domain I in Substrate Recognition
    Erika M. Adkins, Eric L. Barker and Randy D. Blakely
    Molecular Pharmacology March 2001, 59 (3) 514-523; DOI: https://doi.org/10.1124/mol.59.3.514
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    Structural Domains Influencing Sensitivity to Isothiourea Derivative Inhibitor KB-R7943 in Cardiac Na+/Ca2+ Exchanger
    Takahiro Iwamoto, Satomi Kita, Akira Uehara, Yutaka Inoue, Yuki Taniguchi, Issei Imanaga and Munekazu Shigekawa
    Molecular Pharmacology March 2001, 59 (3) 524-531; DOI: https://doi.org/10.1124/mol.59.3.524
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    Inverse Agonist Activity at the α2A-Adrenergic Receptor
    Susan M. Wade, Keng-Li Lan, Dorian J. Moore and Richard R. Neubig
    Molecular Pharmacology March 2001, 59 (3) 532-542; DOI: https://doi.org/10.1124/mol.59.3.532
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    Short- and Long-Term Functional Alterations of the Skeletal Muscle Calcium Release Channel (Ryanodine Receptor) by Suramin: Apparent Dissociation of Single Channel Current Recording and [3H]Ryanodine Binding
    Josef Suko, Gertrude Hellmann and Helmut Drobny
    Molecular Pharmacology March 2001, 59 (3) 543-556; DOI: https://doi.org/10.1124/mol.59.3.543
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    Aryl Hydrocarbon Receptor (AhR)/AhR Nuclear Translocator (ARNT) Activity Is Unaltered by Phosphorylation of a Periodicity/ARNT/Single-Minded (PAS)-Region Serine Residue
    Steven L. Levine and Gary H. Perdew
    Molecular Pharmacology March 2001, 59 (3) 557-566; DOI: https://doi.org/10.1124/mol.59.3.557
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    The Transcription Factor Fos-Related Antigen 1 Is Induced by Thiazolidinediones During Differentiation of 3T3-L1 Cells
    Tatjana Albrektsen and Jan Fleckner
    Molecular Pharmacology March 2001, 59 (3) 567-575; DOI: https://doi.org/10.1124/mol.59.3.567
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    Angiotensin AT1 Receptor Phosphorylation and Desensitization in a Hepatic Cell Line. Roles of Protein Kinase C and Phosphoinositide 3-Kinase
    Agustı́n Garcı́a-Caballero, J. Alberto Olivares-Reyes, Kevin J. Catt and J. Adolfo Garcı́a-Saı́nz
    Molecular Pharmacology March 2001, 59 (3) 576-585; DOI: https://doi.org/10.1124/mol.59.3.576
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    Uptake of Pentamidine in Trypanosoma brucei bruceiis Mediated by Three Distinct Transporters: Implications for Cross-Resistance with Arsenicals
    Harry P. De Koning
    Molecular Pharmacology March 2001, 59 (3) 586-592; DOI: https://doi.org/10.1124/mol.59.3.586
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    Disruption of Cell Adhesion and Caspase-Mediated Proteolysis of β- and γ-Catenins and APC Protein in Paclitaxel-Induced Apoptosis
    Yi-He Ling, Yun Zhong and Roman Perez-Soler
    Molecular Pharmacology March 2001, 59 (3) 593-603; DOI: https://doi.org/10.1124/mol.59.3.593
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    Selective Enhancement of L-Type Calcium Currents by Corticotropin in Acutely Isolated Rat Amygdala Neurons
    Chainllie Young, Ya-Chun Huang, Chih-Hung Lin, Yu-Zen Shen and Po-Wu Gean
    Molecular Pharmacology March 2001, 59 (3) 604-611; DOI: https://doi.org/10.1124/mol.59.3.604
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    Modulation of Synaptic Transmission by Nociceptin/Orphanin FQ and Nocistatin in the Spinal Cord Dorsal Horn of Mutant Mice Lacking the Nociceptin/Orphanin FQ Receptor
    Seifollah Ahmadi, Carolin Kotalla, Hans Gühring, Hiroshi Takeshima, Andreas Pahl and Hanns Ulrich Zeilhofer
    Molecular Pharmacology March 2001, 59 (3) 612-618; DOI: https://doi.org/10.1124/mol.59.3.612
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    Characterization of Recombinant, Soluble β-Secretase from an Insect Cell Expression System
    William D. Mallender, Debra Yager, Luisa Onstead, Michael R. Nichols, Christopher Eckman, Kumar Sambamurti, Lisa M. Kopcho, Jovita Marcinkeviciene, Robert A. Copeland and Terrone L. Rosenberry
    Molecular Pharmacology March 2001, 59 (3) 619-626; DOI: https://doi.org/10.1124/mol.59.3.619
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    Cholestatic Potential of Troglitazone as a Possible Factor Contributing to Troglitazone-Induced Hepatotoxicity: In Vivo and in Vitro Interaction at the Canalicular Bile Salt Export Pump (Bsep) in the Rat
    Christoph Funk, Christiane Ponelle, Gerd Scheuermann and Michael Pantze
    Molecular Pharmacology March 2001, 59 (3) 627-635; DOI: https://doi.org/10.1124/mol.59.3.627
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    Glucuronidation of the Nonsteroidal Antiestrogen EM-652 (SCH 57068), by Human and Monkey Steroid Conjugating UDP-Glucuronosyltransferase Enzymes
    Olivier Barbier, Caroline Albert, Isabelle Martineau, Michel Vallée, Kim High, Fernand Labrie, Dean W. Hum, Claude Labrie and Alain Bélanger
    Molecular Pharmacology March 2001, 59 (3) 636-645; DOI: https://doi.org/10.1124/mol.59.3.636
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    Inhibition of Geranylgeranylation Reduces Angiotensin II-Mediated Free Radical Production in Vascular Smooth Muscle Cells: Involvement of Angiotensin AT1 Receptor Expression and Rac1 GTPase
    Sven Wassmann, Ulrich Laufs, Anselm T. Bäumer, Kirsten Müller, Christian Konkol, Heinrich Sauer, Michael Böhm and Georg Nickenig
    Molecular Pharmacology March 2001, 59 (3) 646-654; DOI: https://doi.org/10.1124/mol.59.3.646

Errata

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    Molecular Pharmacology March 2001, 59 (3) 655; DOI: https://doi.org/10.1124/mol.59.3.655
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    Molecular Pharmacology March 2001, 59 (3) 656; DOI: https://doi.org/10.1124/mol.59.3.656
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Molecular Pharmacology: 59 (3)
Molecular Pharmacology
Vol. 59, Issue 3
1 Mar 2001
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