Competitive CYP2C9 Inhibitors: Enzyme Inhibition Studies, Protein Homology Modeling, and Three-Dimensional Quantitative Structure-Activity Relationship Analysis

	Abstract	Full	Pdf
Mar 2001	36	30	69
Apr 2001	24	41	71
May 2001	10	46	62
Jun 2001	6	30	44
Jul 2001	10	35	28
Aug 2001	8	27	44
Sep 2001	3	12	18
Oct 2001	4	25	40
Nov 2001	2	20	28
Dec 2001	1	3	14
Jan 2002	3	8	33
Feb 2002	5	21	31
Mar 2002	4	25	7
Apr 2002	1	23	35
May 2002	8	17	43
Jun 2002	5	11	21
Jul 2002	3	31	29
Aug 2002	4	22	30
Sep 2002	5	29	42
Oct 2002	1	48	28
Nov 2002	2	42	31
Dec 2002	1	9	26
Jan 2003	5	28	25
Feb 2003	1	28	33
Mar 2003	3	34	58
Apr 2003	2	21	42
May 2003	0	18	28
Jun 2003	7	25	25
Jul 2003	22	63	47
Aug 2003	16	69	91
Sep 2003	18	51	80
Oct 2003	23	68	173
Nov 2003	25	76	137
Dec 2003	18	89	91
Jan 2004	48	76	111
Feb 2004	55	50	83
Mar 2004	64	95	95
Apr 2004	73	79	65
May 2004	24	90	40
Jun 2004	38	85	94
Jul 2004	24	41	51
Aug 2004	17	37	35
Sep 2004	36	74	110
Oct 2004	62	104	111
Nov 2004	44	112	109
Dec 2004	33	97	94
Jan 2005	34	107	66
Feb 2005	40	81	81
Mar 2005	26	119	58
Apr 2005	22	85	46
May 2005	21	72	52
Jun 2005	28	78	57
Jul 2005	12	37	46
Aug 2005	18	30	43
Sep 2005	14	46	39
Oct 2005	34	68	66
Nov 2005	36	78	90
Dec 2005	29	54	78
Jan 2006	32	72	70
Feb 2006	21	77	61
Mar 2006	29	122	65
Apr 2006	21	29	30
May 2006	32	33	63
Jun 2006	35	32	44
Jul 2006	20	27	40
Aug 2006	21	22	25
Sep 2006	24	31	29
Oct 2006	51	73	75
Nov 2006	35	77	62
Dec 2006	33	48	41
Jan 2007	36	33	48
Feb 2007	30	27	42
Mar 2007	52	37	69
Apr 2007	36	40	57
May 2007	30	32	50
Jun 2007	22	37	35
Jul 2007	11	42	50
Aug 2007	19	32	54
Sep 2007	27	25	35
Oct 2007	47	58	55
Nov 2007	33	24	36
Dec 2007	27	32	29
Jan 2008	38	31	56
Feb 2008	42	21	41
Mar 2008	54	24	44
Apr 2008	46	24	46
May 2008	38	30	43
Jun 2008	36	38	36
Jul 2008	26	30	37
Aug 2008	38	34	43
Sep 2008	48	22	31
Oct 2008	35	19	35
Nov 2008	52	18	38
Dec 2008	34	15	35
Jan 2009	32	17	48
Feb 2009	38	31	50
Mar 2009	39	17	43
Apr 2009	32	21	53
May 2009	38	21	58
Jun 2009	25	19	51
Jul 2009	24	23	46
Aug 2009	17	21	52
Sep 2009	23	10	50
Oct 2009	31	28	52
Nov 2009	26	15	79
Dec 2009	23	12	52
Jan 2010	32	22	46
Feb 2010	45	17	59
Mar 2010	33	23	31
Apr 2010	13	47	23
May 2010	23	46	62
Jun 2010	13	21	35
Jul 2010	14	14	30
Aug 2010	18	18	29
Sep 2010	17	22	39
Oct 2010	12	40	55
Nov 2010	9	56	48
Dec 2010	9	37	32
Jan 2011	15	34	48
Feb 2011	14	56	52
Mar 2011	44	48	38
Apr 2011	25	26	32
May 2011	30	42	50
Jun 2011	17	25	15
Jul 2011	29	25	33
Aug 2011	27	26	33
Sep 2011	34	26	49
Oct 2011	31	29	49
Nov 2011	61	48	65
Dec 2011	32	14	38
Jan 2012	23	23	49
Feb 2012	26	24	31
Mar 2012	35	29	52
Apr 2012	37	22	64
May 2012	42	30	46
Jun 2012	23	18	36
Jul 2012	33	27	44
Aug 2012	31	13	33
Sep 2012	26	23	45
Oct 2012	32	35	68
Nov 2012	22	25	69
Dec 2012	30	26	50
Jan 2013	34	41	34
Feb 2013	28	27	51
Mar 2013	33	11	54
Apr 2013	47	28	57
May 2013	35	16	63
Jun 2013	20	50	38
Jul 2013	23	61	28
Aug 2013	21	53	34
Sep 2013	23	160	43
Oct 2013	48	79	34
Nov 2013	32	14	26
Dec 2013	21	39	22
Jan 2014	23	11	17
Feb 2014	31	9	16
Mar 2014	19	9	18
Apr 2014	24	32	18
May 2014	20	20	15
Jun 2014	32	12	20
Jul 2014	16	12	12
Aug 2014	14	14	22
Sep 2014	14	10	13
Oct 2014	20	25	23
Nov 2014	15	17	19
Dec 2014	23	21	25
Jan 2015	18	23	14
Feb 2015	28	16	14
Mar 2015	45	641	18
Apr 2015	67	17	14
May 2015	20	7	16
Jun 2015	19	16	30
Jul 2015	25	325	20
Aug 2015	13	11	16
Sep 2015	30	4	24
Oct 2015	45	14	15
Nov 2015	13	6	20
Dec 2015	28	6	23
Jan 2016	12	8	11
Feb 2016	33	16	34
Mar 2016	63	13	31
Apr 2016	35	3	21
May 2016	21	7	21
Jun 2016	31	8	35
Jul 2016	63	2	29
Aug 2016	52	15	33
Sep 2016	43	13	29
Oct 2016	23	22	60
Nov 2016	15	6	31
Dec 2016	15	15	38
Jan 2017	6	7	30
Feb 2017	13	6	25
Mar 2017	4	7	26
Apr 2017	10	13	13
May 2017	5	14	20
Jun 2017	4	13	16
Jul 2017	5	18	9
Aug 2017	4	10	16
Sep 2017	6	22	24
Oct 2017	8	11	12
Nov 2017	12	37	27
Dec 2017	13	24	10
Jan 2018	12	20	13
Feb 2018	15	15	17
Mar 2018	5	29	16
Apr 2018	8	29	17
May 2018	6	12	22
Jun 2018	5	23	22
Jul 2018	1	7	21
Aug 2018	5	7	18
Sep 2018	2	7	12
Oct 2018	9	40	24
Nov 2018	5	57	11
Dec 2018	63	16	18
Jan 2019	62	0	10
Feb 2019	46	1	2
Mar 2019	34	4	7
Apr 2019	31	1	4
May 2019	23	1	6
Jun 2019	28	0	1
Jul 2019	19	0	3
Aug 2019	16	1	1
Sep 2019	36	0	4
Oct 2019	43	0	6
Nov 2019	31	1	1
Dec 2019	30	5	6
Jan 2020	17	1	1
Feb 2020	16	1	1
Mar 2020	24	2	2
Apr 2020	28	0	5
May 2020	26	1	3
Jun 2020	16	2	4
Jul 2020	14	2	0
Aug 2020	17	2	4
Sep 2020	33	1	4
Oct 2020	16	3	2
Nov 2020	26	0	1
Dec 2020	30	4	1
Jan 2021	10	10	2
Feb 2021	23	7	8
Mar 2021	22	2	3
Apr 2021	9	2	1
May 2021	19	3	3
Jun 2021	10	6	2
Jul 2021	14	6	2
Aug 2021	11	5	4
Sep 2021	11	5	0
Oct 2021	17	1	1
Nov 2021	26	5	3
Dec 2021	25	2	1
Jan 2022	20	2	0
Feb 2022	17	1	1
Mar 2022	17	5	6
Apr 2022	24	2	0