Table of Contents

Articles

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  Cloning, Expression, Signaling Mechanisms, and Membrane Targeting of P2Y₁₁ Receptors in Madin Darby Canine Kidney Cells

  Alexander C. Zambon, Laurence L. Brunton, Kim E. Barrett, Richard J. Hughes, Brian Torres and Paul A. Insel

  Molecular Pharmacology July 2001, 60 (1) 26-35; DOI: https://doi.org/10.1124/mol.60.1.26
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  Prostaglandin Receptor EP₄ Mediates the Bone Anabolic Effects of PGE₂

  M. Machwate, S. Harada, C. T. Leu, G. Seedor, M. Labelle, M. Gallant, S. Hutchins, N. Lachance, N. Sawyer, D. Slipetz, K. M. Metters, S. B. Rodan, R. Young and G. A. Rodan

  Molecular Pharmacology July 2001, 60 (1) 36-41; DOI: https://doi.org/10.1124/mol.60.1.36
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  Pituitary Adenylate Cyclase-Activating Polypeptide Stimulates Secretoneurin Release and Secretogranin II Gene Transcription in Bovine Adrenochromaffin Cells through Multiple Signaling Pathways and Increased Binding of Pre-Existing Activator Protein-1-Like Transcription Factors

  Valerie Turquier, Laurent Yon, Luca Grumolato, David Alexandre, Alain Fournier, Hubert Vaudry and Youssef Anouar

  Molecular Pharmacology July 2001, 60 (1) 42-52; DOI: https://doi.org/10.1124/mol.60.1.42
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  Chronic Exposure to μ-Opioid Agonists Produces Constitutive Activation of μ-Opioid Receptors in Direct Proportion to the Efficacy of the Agonist Used for Pretreatment

  Jing-Gen Liu and Paul L. Prather

  Molecular Pharmacology July 2001, 60 (1) 53-62; DOI: https://doi.org/10.1124/mol.60.1.53
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  Nerve Growth Factor Stimulation of p42/p44 Mitogen-Activated Protein Kinase in PC12 Cells: Role of G_i/o, G Protein-Coupled Receptor Kinase 2, β-Arrestin I, and Endocytic Processing

  Soma Rakhit, Susan Pyne and Nigel J. Pyne

  Molecular Pharmacology July 2001, 60 (1) 63-70; DOI: https://doi.org/10.1124/mol.60.1.63
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  Specific Activation of the α7 Nicotinic Acetylcholine Receptor by a Quaternary Analog of Cocaine

  Michael M. Francis, Elaine Y. Cheng, Gregory A. Weiland and Robert E. Oswald

  Molecular Pharmacology July 2001, 60 (1) 71-79; DOI: https://doi.org/10.1124/mol.60.1.71
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  Complex Intracellular Messenger Pathways Regulate One Type of Neuronal α-Bungarotoxin-Resistant Nicotinic Acetylcholine Receptors Expressed in Insect Neurosecretory Cells (Dorsal Unpaired Median Neurons)

  Raphaël Courjaret and Bruno Lapied

  Molecular Pharmacology July 2001, 60 (1) 80-91; DOI: https://doi.org/10.1124/mol.60.1.80
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  Dopamine D₄ and D_2L Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent ontrans-Activation of the Platelet-Derived Growth Factor Receptor

  James N. Oak, Natalie Lavine and Hubert H. M. Van Tol

  Molecular Pharmacology July 2001, 60 (1) 92-103; DOI: https://doi.org/10.1124/mol.60.1.92
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  The Use of a Novel Taxane-Based P-Glycoprotein Inhibitor to Identify Mutations That Alter the Interaction of the Protein with Paclitaxel

  Donald J. Gruol, Josh Bernd, Alba E. Phippard, Iwao Ojima and Ralph J. Bernacki

  Molecular Pharmacology July 2001, 60 (1) 104-113; DOI: https://doi.org/10.1124/mol.60.1.104
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  Reciprocal Modulation of Voltage-Gated and Background K⁺ Channels Mediated by Nucleotides and Corticotropin

  John J. Enyeart, Lin Xu, Juan Carlos Gomora and Judith A. Enyeart

  Molecular Pharmacology July 2001, 60 (1) 114-123; DOI: https://doi.org/10.1124/mol.60.1.114
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  The Peptide YY-Preferring Receptor Mediating Inhibition of Small Intestinal Secretion Is a Peripheral Y₂ Receptor: Pharmacological Evidence and Molecular Cloning

  Mathieu Goumain, Thierry Voisin, Anne-Marie Lorinet, Robert Ducroc, Annick Tsocas, Claude Rozé, Patricia Rouet-Benzineb, Herbert Herzog, Ambikaipakan Balasubramaniam and Marc Laburthe

  Molecular Pharmacology July 2001, 60 (1) 124-134; DOI: https://doi.org/10.1124/mol.60.1.124
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  Immune-Specific Up-Regulation of Adseverin Gene Expression by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

  Camilla Svensson and Katarina Lundberg

  Molecular Pharmacology July 2001, 60 (1) 135-142; DOI: https://doi.org/10.1124/mol.60.1.135
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  Sequence-Dependent Potentiation of Paclitaxel-Mediated Apoptosis in Human Leukemia Cells by Inhibitors of the Mitogen-Activated Protein Kinase Kinase/Mitogen-Activated Protein Kinase Pathway

  Chunrong Yu, Shujie Wang, Paul Dent and Steven Grant

  Molecular Pharmacology July 2001, 60 (1) 143-154; DOI: https://doi.org/10.1124/mol.60.1.143
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  Evidence for a New G Protein-Coupled Cannabinoid Receptor in Mouse Brain

  Christopher S. Breivogel, Graeme Griffin, Vincenzo Di Marzo and Billy R. Martin

  Molecular Pharmacology July 2001, 60 (1) 155-163; DOI: https://doi.org/10.1124/mol.60.1.155
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  Mutation of Asp¹⁷¹ and Asp²⁶² of the Chemokine Receptor CXCR4 Impairs Its Coreceptor Function for Human Immunodeficiency Virus-1 Entry and Abrogates the Antagonistic Activity of AMD3100

  Sigrid Hatse, Katrien Princen, Lars-Ole Gerlach, Gary Bridger, Geoffrey Henson, Erik De Clercq, Thue W. Schwartz and Dominique Schols

  Molecular Pharmacology July 2001, 60 (1) 164-173; DOI: https://doi.org/10.1124/mol.60.1.164
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  C-Myc Down-Regulation Increases Susceptibility to Cisplatin through Reactive Oxygen Species-Mediated Apoptosis in M14 Human Melanoma Cells

  Annamaria Biroccio, Barbara Benassi, Sarah Amodei, Chiara Gabellini, Donatella Del Bufalo and Gabriella Zupi

  Molecular Pharmacology July 2001, 60 (1) 174-182; DOI: https://doi.org/10.1124/mol.60.1.174
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  Memantine Inhibits Efferent Cholinergic Transmission in the Cochlea by Blocking Nicotinic Acetylcholine Receptors of Outer Hair Cells

  Dominik Oliver, Jost Ludwig, Ellen Reisinger, Werner Zoellner, J. Peter Ruppersberg and Bernd Fakler

  Molecular Pharmacology July 2001, 60 (1) 183-189; DOI: https://doi.org/10.1124/mol.60.1.183
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  Characterization of a Mutant Sulfonylurea Receptor SUR2B with High Affinity for Sulfonylureas and Openers: Differences in the Coupling to Kir6.x Subtypes

  Annette Hambrock, Cornelia Löffler-Walz, Ulrich Russ, Ulf Lange and Ulrich Quast

  Molecular Pharmacology July 2001, 60 (1) 190-199; DOI: https://doi.org/10.1124/mol.60.1.190
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  Fast and Slow Gating of CLC-1: Differential Effects of 2-(4-Chlorophenoxy) Propionic Acid and Dominant Negative Mutations

  E. C. Aromataris, G. Y. Rychkov, B. Bennetts, B. P. Hughes, A. H. Bretag and M. L. Roberts

  Molecular Pharmacology July 2001, 60 (1) 200-208; DOI: https://doi.org/10.1124/mol.60.1.200
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  Role of Nitric Oxide in Down-Regulation of CYP2B1 Protein, but Not RNA, in Primary Cultures of Rat Hepatocytes

  Luc Ferrari, Ning Peng, James R. Halpert and Edward T. Morgan

  Molecular Pharmacology July 2001, 60 (1) 209-216; DOI: https://doi.org/10.1124/mol.60.1.209
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  Resveratrol Inhibits Phorbol Ester and UV-Induced Activator Protein 1 Activation by Interfering with Mitogen-Activated Protein Kinase Pathways

  Rong Yu, Vidya Hebbar, Daniel W. Kim, Sandhya Mandlekar, John M. Pezzuto and Ah-Ng Tony Kong

  Molecular Pharmacology July 2001, 60 (1) 217-224; DOI: https://doi.org/10.1124/mol.60.1.217
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  Mechanism of Mitotic Block and Inhibition of Cell Proliferation by the Semisynthetic Vinca Alkaloids Vinorelbine and Its Newer Derivative Vinflunine

  Vivian K. Ngan, Krista Bellman, Bridget T. Hill, Leslie Wilson and Mary Ann Jordan

  Molecular Pharmacology July 2001, 60 (1) 225-232; DOI: https://doi.org/10.1124/mol.60.1.225