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Molecular Pharmacology

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Table of Contents

July 01, 2001; Volume 60,Issue 1

MINIREVIEW

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    Structural Mimicry in G Protein-Coupled Receptors: Implications of the High-Resolution Structure of Rhodopsin for Structure-Function Analysis of Rhodopsin-Like Receptors
    Juan A. Ballesteros, Lei Shi and Jonathan A. Javitch
    Molecular Pharmacology July 2001, 60 (1) 1-19; DOI: https://doi.org/10.1124/mol.60.1.1

Perspective

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    Regulation of Opioid Receptor Function by Chronic Agonist Exposure: Constitutive Activity and Desensitization
    Charles Chavkin, Jay P. McLaughlin and Jeremy P. Celver
    Molecular Pharmacology July 2001, 60 (1) 20-25; DOI: https://doi.org/10.1124/mol.60.1.20

Articles

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    Cloning, Expression, Signaling Mechanisms, and Membrane Targeting of P2Y11 Receptors in Madin Darby Canine Kidney Cells
    Alexander C. Zambon, Laurence L. Brunton, Kim E. Barrett, Richard J. Hughes, Brian Torres and Paul A. Insel
    Molecular Pharmacology July 2001, 60 (1) 26-35; DOI: https://doi.org/10.1124/mol.60.1.26
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    Prostaglandin Receptor EP4 Mediates the Bone Anabolic Effects of PGE2
    M. Machwate, S. Harada, C. T. Leu, G. Seedor, M. Labelle, M. Gallant, S. Hutchins, N. Lachance, N. Sawyer, D. Slipetz, K. M. Metters, S. B. Rodan, R. Young and G. A. Rodan
    Molecular Pharmacology July 2001, 60 (1) 36-41; DOI: https://doi.org/10.1124/mol.60.1.36
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    Pituitary Adenylate Cyclase-Activating Polypeptide Stimulates Secretoneurin Release and Secretogranin II Gene Transcription in Bovine Adrenochromaffin Cells through Multiple Signaling Pathways and Increased Binding of Pre-Existing Activator Protein-1-Like Transcription Factors
    Valerie Turquier, Laurent Yon, Luca Grumolato, David Alexandre, Alain Fournier, Hubert Vaudry and Youssef Anouar
    Molecular Pharmacology July 2001, 60 (1) 42-52; DOI: https://doi.org/10.1124/mol.60.1.42
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    Chronic Exposure to μ-Opioid Agonists Produces Constitutive Activation of μ-Opioid Receptors in Direct Proportion to the Efficacy of the Agonist Used for Pretreatment
    Jing-Gen Liu and Paul L. Prather
    Molecular Pharmacology July 2001, 60 (1) 53-62; DOI: https://doi.org/10.1124/mol.60.1.53
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    Nerve Growth Factor Stimulation of p42/p44 Mitogen-Activated Protein Kinase in PC12 Cells: Role of Gi/o, G Protein-Coupled Receptor Kinase 2, β-Arrestin I, and Endocytic Processing
    Soma Rakhit, Susan Pyne and Nigel J. Pyne
    Molecular Pharmacology July 2001, 60 (1) 63-70; DOI: https://doi.org/10.1124/mol.60.1.63
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    Specific Activation of the α7 Nicotinic Acetylcholine Receptor by a Quaternary Analog of Cocaine
    Michael M. Francis, Elaine Y. Cheng, Gregory A. Weiland and Robert E. Oswald
    Molecular Pharmacology July 2001, 60 (1) 71-79; DOI: https://doi.org/10.1124/mol.60.1.71
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    Complex Intracellular Messenger Pathways Regulate One Type of Neuronal α-Bungarotoxin-Resistant Nicotinic Acetylcholine Receptors Expressed in Insect Neurosecretory Cells (Dorsal Unpaired Median Neurons)
    Raphaël Courjaret and Bruno Lapied
    Molecular Pharmacology July 2001, 60 (1) 80-91; DOI: https://doi.org/10.1124/mol.60.1.80
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    Dopamine D4 and D2L Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent ontrans-Activation of the Platelet-Derived Growth Factor Receptor
    James N. Oak, Natalie Lavine and Hubert H. M. Van Tol
    Molecular Pharmacology July 2001, 60 (1) 92-103; DOI: https://doi.org/10.1124/mol.60.1.92
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    The Use of a Novel Taxane-Based P-Glycoprotein Inhibitor to Identify Mutations That Alter the Interaction of the Protein with Paclitaxel
    Donald J. Gruol, Josh Bernd, Alba E. Phippard, Iwao Ojima and Ralph J. Bernacki
    Molecular Pharmacology July 2001, 60 (1) 104-113; DOI: https://doi.org/10.1124/mol.60.1.104
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    Reciprocal Modulation of Voltage-Gated and Background K+ Channels Mediated by Nucleotides and Corticotropin
    John J. Enyeart, Lin Xu, Juan Carlos Gomora and Judith A. Enyeart
    Molecular Pharmacology July 2001, 60 (1) 114-123; DOI: https://doi.org/10.1124/mol.60.1.114
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    The Peptide YY-Preferring Receptor Mediating Inhibition of Small Intestinal Secretion Is a Peripheral Y2 Receptor: Pharmacological Evidence and Molecular Cloning
    Mathieu Goumain, Thierry Voisin, Anne-Marie Lorinet, Robert Ducroc, Annick Tsocas, Claude Rozé, Patricia Rouet-Benzineb, Herbert Herzog, Ambikaipakan Balasubramaniam and Marc Laburthe
    Molecular Pharmacology July 2001, 60 (1) 124-134; DOI: https://doi.org/10.1124/mol.60.1.124
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    Immune-Specific Up-Regulation of Adseverin Gene Expression by 2,3,7,8-Tetrachlorodibenzo-p-dioxin
    Camilla Svensson and Katarina Lundberg
    Molecular Pharmacology July 2001, 60 (1) 135-142; DOI: https://doi.org/10.1124/mol.60.1.135
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    Sequence-Dependent Potentiation of Paclitaxel-Mediated Apoptosis in Human Leukemia Cells by Inhibitors of the Mitogen-Activated Protein Kinase Kinase/Mitogen-Activated Protein Kinase Pathway
    Chunrong Yu, Shujie Wang, Paul Dent and Steven Grant
    Molecular Pharmacology July 2001, 60 (1) 143-154; DOI: https://doi.org/10.1124/mol.60.1.143
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    Evidence for a New G Protein-Coupled Cannabinoid Receptor in Mouse Brain
    Christopher S. Breivogel, Graeme Griffin, Vincenzo Di Marzo and Billy R. Martin
    Molecular Pharmacology July 2001, 60 (1) 155-163; DOI: https://doi.org/10.1124/mol.60.1.155
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    Mutation of Asp171 and Asp262 of the Chemokine Receptor CXCR4 Impairs Its Coreceptor Function for Human Immunodeficiency Virus-1 Entry and Abrogates the Antagonistic Activity of AMD3100
    Sigrid Hatse, Katrien Princen, Lars-Ole Gerlach, Gary Bridger, Geoffrey Henson, Erik De Clercq, Thue W. Schwartz and Dominique Schols
    Molecular Pharmacology July 2001, 60 (1) 164-173; DOI: https://doi.org/10.1124/mol.60.1.164
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    C-Myc Down-Regulation Increases Susceptibility to Cisplatin through Reactive Oxygen Species-Mediated Apoptosis in M14 Human Melanoma Cells
    Annamaria Biroccio, Barbara Benassi, Sarah Amodei, Chiara Gabellini, Donatella Del Bufalo and Gabriella Zupi
    Molecular Pharmacology July 2001, 60 (1) 174-182; DOI: https://doi.org/10.1124/mol.60.1.174
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    Memantine Inhibits Efferent Cholinergic Transmission in the Cochlea by Blocking Nicotinic Acetylcholine Receptors of Outer Hair Cells
    Dominik Oliver, Jost Ludwig, Ellen Reisinger, Werner Zoellner, J. Peter Ruppersberg and Bernd Fakler
    Molecular Pharmacology July 2001, 60 (1) 183-189; DOI: https://doi.org/10.1124/mol.60.1.183
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    Characterization of a Mutant Sulfonylurea Receptor SUR2B with High Affinity for Sulfonylureas and Openers: Differences in the Coupling to Kir6.x Subtypes
    Annette Hambrock, Cornelia Löffler-Walz, Ulrich Russ, Ulf Lange and Ulrich Quast
    Molecular Pharmacology July 2001, 60 (1) 190-199; DOI: https://doi.org/10.1124/mol.60.1.190
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    Fast and Slow Gating of CLC-1: Differential Effects of 2-(4-Chlorophenoxy) Propionic Acid and Dominant Negative Mutations
    E. C. Aromataris, G. Y. Rychkov, B. Bennetts, B. P. Hughes, A. H. Bretag and M. L. Roberts
    Molecular Pharmacology July 2001, 60 (1) 200-208; DOI: https://doi.org/10.1124/mol.60.1.200
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    Role of Nitric Oxide in Down-Regulation of CYP2B1 Protein, but Not RNA, in Primary Cultures of Rat Hepatocytes
    Luc Ferrari, Ning Peng, James R. Halpert and Edward T. Morgan
    Molecular Pharmacology July 2001, 60 (1) 209-216; DOI: https://doi.org/10.1124/mol.60.1.209
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    Resveratrol Inhibits Phorbol Ester and UV-Induced Activator Protein 1 Activation by Interfering with Mitogen-Activated Protein Kinase Pathways
    Rong Yu, Vidya Hebbar, Daniel W. Kim, Sandhya Mandlekar, John M. Pezzuto and Ah-Ng Tony Kong
    Molecular Pharmacology July 2001, 60 (1) 217-224; DOI: https://doi.org/10.1124/mol.60.1.217
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    Mechanism of Mitotic Block and Inhibition of Cell Proliferation by the Semisynthetic Vinca Alkaloids Vinorelbine and Its Newer Derivative Vinflunine
    Vivian K. Ngan, Krista Bellman, Bridget T. Hill, Leslie Wilson and Mary Ann Jordan
    Molecular Pharmacology July 2001, 60 (1) 225-232; DOI: https://doi.org/10.1124/mol.60.1.225

Erratum

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    Correction to “High-intensity p38 kinase activity is critical for p21 cip1 induction and the antiproliferative function of Gi protein-coupled receptors”
    Molecular Pharmacology July 2001, 60 (1) 233; DOI: https://doi.org/10.1124/mol.60.1.233
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Molecular Pharmacology: 60 (1)
Molecular Pharmacology
Vol. 60, Issue 1
1 Jul 2001
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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