Advertisement
Research ArticleArticle

Mutation of Asp171 and Asp262 of the Chemokine Receptor CXCR4 Impairs Its Coreceptor Function for Human Immunodeficiency Virus-1 Entry and Abrogates the Antagonistic Activity of AMD3100

Sigrid Hatse, Katrien Princen, Lars-Ole Gerlach, Gary Bridger, Geoffrey Henson, Erik De Clercq, Thue W. Schwartz and Dominique Schols
Molecular Pharmacology July 2001, 60 (1) 164-173; DOI: https://doi.org/10.1124/mol.60.1.164

Article Information

vol. 60 no. 1 164-173
DOI 
https://doi.org/10.1124/mol.60.1.164
PubMed 
11408611
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 19, 2000
  • Accepted March 29, 2000
  • Published online July 1, 2001.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Sigrid Hatse1,
  2. Katrien Princen1,
  3. Lars-Ole Gerlach2,
  4. Gary Bridger3,
  5. Geoffrey Henson3,
  6. Erik De Clercq1,
  7. Thue W. Schwartz2 and
  8. Dominique Schols1
  1. 1Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium (S.H., K.P., E.D.C., D.S.); 2The Panum Institute, Copenhagen, Denmark (L-O.G., T.W.S.); and 3AnorMed, Langley, British Columbia, Canada (G.B., G.H.)
  1. Sigrid Hatse, Rega Institute for Medical Research, Minderbroedersstraat 10, B-3000 Leuven, Belgium. E-mail: sigrid.hatse{at}rega.kuleuven.ac.be
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: June 2001 to May 2022

AbstractFullPdf
Jun 2001264955
Jul 2001108259
Aug 200144332
Sep 200132718
Oct 200121914
Nov 200172716
Dec 20010178
Jan 200242621
Feb 20027219
Mar 200231810
Apr 200272916
May 200201814
Jun 200231115
Jul 200222421
Aug 2002239
Sep 200231319
Oct 200201821
Nov 200211612
Dec 20023108
Jan 200312222
Feb 200311615
Mar 200321717
Apr 20030411
May 200312818
Jun 200322424
Jul 20035208
Aug 200351813
Sep 200382513
Oct 200392911
Nov 2003123216
Dec 20039225
Jan 20045173
Feb 200432414
Mar 2004123015
Apr 20048359
May 2004112210
Jun 2004114316
Jul 200415264
Aug 20049254
Sep 200412339
Oct 200420509
Nov 200484121
Dec 200472712
Jan 2005133911
Feb 200511488
Mar 2005172510
Apr 20051129
May 200511305
Jun 200513327
Jul 20056329
Aug 200572512
Sep 200592615
Oct 20055227
Nov 20056216
Dec 200542324
Jan 20066227
Feb 20065299
Mar 2006121816
Apr 200692110
May 20066186
Jun 200614185
Jul 20068159
Aug 200651812
Sep 200643016
Oct 200632715
Nov 20066157
Dec 20063123
Jan 2007396
Feb 200731515
Mar 20074145
Apr 200762612
May 20074144
Jun 20073148
Jul 200772014
Aug 20075135
Sep 20075147
Oct 200711311
Nov 20071108
Dec 2007267
Jan 20087139
Feb 20089816
Mar 200819138
Apr 2008161213
May 20081489
Jun 20088192
Jul 2008191213
Aug 2008292810
Sep 2008861913
Oct 2008107134
Nov 20081284
Dec 2008697
Jan 200923134
Feb 2009112413
Mar 2009152018
Apr 200911138
May 200992016
Jun 20094137
Jul 2009111711
Aug 20096153
Sep 200932175
Oct 200920115
Nov 2009341310
Dec 2009161912
Jan 2010858
Feb 2010241
Mar 2010693
Apr 2010271
May 201017118
Jun 201011147
Jul 20105115
Aug 20103308
Sep 201011193
Oct 20109189
Nov 201042311
Dec 20103205
Jan 2011132315
Feb 20117275
Mar 201114149
Apr 2011102913
May 2011113115
Jun 2011133912
Jul 2011112315
Aug 2011111315
Sep 201115148
Oct 2011111710
Nov 2011162310
Dec 2011141916
Jan 2012112515
Feb 2012152414
Mar 201291912
Apr 2012272221
May 201212166
Jun 2012171011
Jul 201212810
Aug 201215711
Sep 201212612
Oct 2012151317
Nov 201281510
Dec 201211149
Jan 2013241815
Feb 2013111817
Mar 2013171610
Apr 2013161224
May 2013131715
Jun 201331221
Jul 201310912
Aug 20133912
Sep 201320258
Oct 2013132510
Nov 201320208
Dec 2013113310
Jan 201427610
Feb 2014121117
Mar 2014111815
Apr 201491122
May 2014132113
Jun 2014243013
Jul 201462515
Aug 20149209
Sep 201451610
Oct 2014121526
Nov 2014241917
Dec 2014444443
Jan 2015232120
Feb 201511142
Mar 201515118
Apr 2015584
May 201582010
Jun 201514183
Jul 2015211513
Aug 2015122012
Sep 20151172
Oct 2015753
Nov 2015643
Dec 20156123
Jan 2016932
Feb 20169227
Mar 201613189
Apr 2016475
May 20167149
Jun 20161485
Jul 2016875
Aug 201610911
Sep 20168135
Oct 20162295
Nov 20169242
Dec 201631116
Jan 201725913
Feb 201702195
Mar 201708323
Apr 2017014519
May 20170367
Jun 20170195
Jul 20172118
Aug 20170154
Sep 20170184
Oct 20170124
Nov 20172358
Dec 20170179
Jan 20182368
Feb 20180235
Mar 20180204
Apr 20182176
May 201811715
Jun 20180144
Jul 20180138
Aug 20180956
Sep 20180484
Oct 20180294
Nov 20180515
Dec 201828121
Jan 20194511
Feb 20192121
Mar 20191910
Apr 20191720
May 20192243
Jun 20192202
Jul 2019900
Aug 20191811
Sep 20193700
Oct 201910520
Nov 20195721
Dec 20192831
Jan 2020820
Feb 20201320
Mar 20201320
Apr 20201612
May 20201211
Jun 20202800
Jul 20201100
Aug 2020502
Sep 20201940
Oct 2020700
Nov 20201500
Dec 20201821
Jan 20211081
Feb 20211550
Mar 20211721
Apr 2021710
May 2021731
Jun 20213070
Jul 20211824
Aug 20211232
Sep 20211812
Oct 20211631
Nov 2021900
Dec 20212423
Jan 20221710
Feb 2022940
Mar 20221022
Apr 2022630
May 2022710

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleArticle

Mutation of Asp171 and Asp262 of the Chemokine Receptor CXCR4 Impairs Its Coreceptor Function for Human Immunodeficiency Virus-1 Entry and Abrogates the Antagonistic Activity of AMD3100

Sigrid Hatse, Katrien Princen, Lars-Ole Gerlach, Gary Bridger, Geoffrey Henson, Erik De Clercq, Thue W. Schwartz and Dominique Schols
Molecular Pharmacology July 1, 2001, 60 (1) 164-173; DOI: https://doi.org/10.1124/mol.60.1.164
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo

Jump to section

Advertisement