Selective Potentiation of Paclitaxel (Taxol)-Induced Cell Death by Mitogen-Activated Protein Kinase Kinase Inhibition in Human Cancer Cell Lines

Dr. Susan B. Horwitz, Department of Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY 10461. E-mail:shorwitz{at}aecom.yu.edu

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	Abstract	Full	Pdf
Jul 2001	41	96	85
Aug 2001	26	102	96
Sep 2001	13	71	65
Oct 2001	16	76	45
Nov 2001	10	49	35
Dec 2001	6	35	33
Jan 2002	3	36	30
Feb 2002	6	33	18
Mar 2002	4	19	11
Apr 2002	1	34	18
May 2002	2	20	16
Jun 2002	5	28	13
Jul 2002	3	25	17
Aug 2002	0	22	30
Sep 2002	9	26	29
Oct 2002	2	19	25
Nov 2002	7	22	29
Dec 2002	2	13	16
Jan 2003	1	22	28
Feb 2003	6	19	29
Mar 2003	6	23	34
Apr 2003	2	22	41
May 2003	3	26	33
Jun 2003	5	16	11
Jul 2003	9	53	81
Aug 2003	10	38	17
Sep 2003	19	48	28
Oct 2003	15	79	33
Nov 2003	25	64	28
Dec 2003	17	45	31
Jan 2004	20	43	14
Feb 2004	20	43	38
Mar 2004	27	73	68
Apr 2004	13	47	15
May 2004	21	65	37
Jun 2004	51	99	20
Jul 2004	34	82	22
Aug 2004	23	79	19
Sep 2004	24	83	20
Oct 2004	18	68	21
Nov 2004	16	74	35
Dec 2004	23	60	25
Jan 2005	34	66	48
Feb 2005	19	60	21
Mar 2005	18	71	39
Apr 2005	5	42	24
May 2005	17	56	24
Jun 2005	8	40	17
Jul 2005	12	54	29
Aug 2005	5	44	30
Sep 2005	8	42	22
Oct 2005	6	41	8
Nov 2005	21	61	25
Dec 2005	18	41	19
Jan 2006	11	48	23
Feb 2006	10	40	18
Mar 2006	13	41	19
Apr 2006	4	33	21
May 2006	5	20	14
Jun 2006	12	26	13
Jul 2006	10	33	18
Aug 2006	5	30	10
Sep 2006	9	16	19
Oct 2006	14	34	16
Nov 2006	6	36	21
Dec 2006	7	21	19
Jan 2007	9	25	21
Feb 2007	5	13	11
Mar 2007	15	15	29
Apr 2007	10	35	13
May 2007	3	30	33
Jun 2007	8	29	20
Jul 2007	12	22	16
Aug 2007	8	14	4
Sep 2007	18	20	23
Oct 2007	11	27	16
Nov 2007	10	25	21
Dec 2007	3	15	22
Jan 2008	6	20	21
Feb 2008	6	20	17
Mar 2008	7	28	19
Apr 2008	11	12	15
May 2008	16	14	7
Jun 2008	17	23	20
Jul 2008	10	18	25
Aug 2008	133	21	7
Sep 2008	61	17	10
Oct 2008	26	17	12
Nov 2008	41	13	21
Dec 2008	10	13	8
Jan 2009	9	22	9
Feb 2009	17	24	20
Mar 2009	24	14	7
Apr 2009	28	16	11
May 2009	8	17	9
Jun 2009	5	22	13
Jul 2009	13	22	15
Aug 2009	1	16	3
Sep 2009	11	15	10
Oct 2009	19	14	14
Nov 2009	26	5	3
Dec 2009	16	9	13
Jan 2010	6	9	6
Feb 2010	9	21	10
Mar 2010	5	18	11
Apr 2010	4	16	8
May 2010	11	18	8
Jun 2010	8	16	14
Jul 2010	13	20	19
Aug 2010	6	27	10
Sep 2010	6	16	8
Oct 2010	8	18	7
Nov 2010	11	19	14
Dec 2010	10	22	15
Jan 2011	11	13	8
Feb 2011	10	12	13
Mar 2011	4	12	17
Apr 2011	9	26	25
May 2011	11	18	16
Jun 2011	14	18	19
Jul 2011	7	14	15
Aug 2011	17	9	17
Sep 2011	20	21	13
Oct 2011	15	25	29
Nov 2011	8	25	14
Dec 2011	8	28	19
Jan 2012	9	18	17
Feb 2012	8	37	18
Mar 2012	16	23	20
Apr 2012	8	29	19
May 2012	25	30	26
Jun 2012	5	13	19
Jul 2012	9	19	15
Aug 2012	7	12	16
Sep 2012	25	19	22
Oct 2012	7	33	24
Nov 2012	5	26	25
Dec 2012	4	18	28
Jan 2013	15	25	22
Feb 2013	7	36	44
Mar 2013	8	27	28
Apr 2013	8	13	31
May 2013	6	18	34
Jun 2013	2	15	31
Jul 2013	2	14	16
Aug 2013	1	11	26
Sep 2013	8	25	28
Oct 2013	10	8	42
Nov 2013	7	7	22
Dec 2013	5	8	15
Jan 2014	9	13	21
Feb 2014	9	17	28
Mar 2014	15	13	17
Apr 2014	8	12	35
May 2014	8	14	32
Jun 2014	9	16	22
Jul 2014	8	19	15
Aug 2014	6	8	18
Sep 2014	7	9	15
Oct 2014	6	19	9
Nov 2014	7	17	13
Dec 2014	16	11	9
Jan 2015	5	13	26
Feb 2015	5	4	10
Mar 2015	9	4	14
Apr 2015	3	6	55
May 2015	11	7	39
Jun 2015	8	0	16
Jul 2015	4	7	25
Aug 2015	2	10	5
Sep 2015	16	8	9
Oct 2015	1	6	14
Nov 2015	10	2	12
Dec 2015	6	31	17
Jan 2016	2	9	4
Feb 2016	3	16	4
Mar 2016	14	16	525
Apr 2016	26	13	321
May 2016	13	11	6
Jun 2016	9	6	11
Jul 2016	5	11	16
Aug 2016	1	12	15
Sep 2016	3	9	10
Oct 2016	5	19	10
Nov 2016	0	9	4
Dec 2016	0	13	0
Jan 2017	1	16	0
Feb 2017	0	11	2
Mar 2017	2	15	6
Apr 2017	3	11	4
May 2017	0	18	3
Jun 2017	2	16	14
Jul 2017	0	16	4
Aug 2017	0	19	17
Sep 2017	3	21	10
Oct 2017	0	20	11
Nov 2017	0	15	5
Dec 2017	0	18	7
Jan 2018	0	27	9
Feb 2018	1	7	7
Mar 2018	0	20	8
Apr 2018	1	11	8
May 2018	2	16	17
Jun 2018	1	17	11
Jul 2018	0	26	12
Aug 2018	4	90	4
Sep 2018	1	49	11
Oct 2018	1	51	12
Nov 2018	1	73	3
Dec 2018	56	16	2
Jan 2019	55	0	3
Feb 2019	43	1	0
Mar 2019	38	5	2
Apr 2019	5	1	1
May 2019	7	2	1
Jun 2019	11	0	2
Jul 2019	15	1	1
Aug 2019	10	2	5
Sep 2019	130	1	0
Oct 2019	29	3	1
Nov 2019	29	0	1
Dec 2019	29	1	1
Jan 2020	21	0	1
Feb 2020	9	2	1
Mar 2020	6	0	0
Apr 2020	7	2	0
May 2020	5	0	0
Jun 2020	29	1	0
Jul 2020	9	1	2
Aug 2020	6	4	3
Sep 2020	8	0	0
Oct 2020	35	2	1
Nov 2020	14	0	0
Dec 2020	15	2	0
Jan 2021	20	2	4
Feb 2021	17	4	2
Mar 2021	17	2	0
Apr 2021	32	3	4
May 2021	17	5	1
Jun 2021	12	1	1
Jul 2021	9	3	1
Aug 2021	18	2	0
Sep 2021	18	3	0
Oct 2021	26	6	1
Nov 2021	16	4	0
Dec 2021	34	2	0
Jan 2022	12	1	2