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Molecular Pharmacology

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Research ArticleArticle

Cell-Type Specific Effects of Endocytosis Inhibitors on 5-Hydroxytryptamine2A Receptor Desensitization and Resensitization Reveal an Arrestin-, GRK2-, and GRK5-Independent Mode of Regulation in Human Embryonic Kidney 293 Cells

John A. Gray, Douglas J. Sheffler, Anushree Bhatnagar, Jason A. Woods, Sandra J. Hufeisen, Jeffrey L. Benovic and Bryan L. Roth
Molecular Pharmacology November 2001, 60 (5) 1020-1030; DOI: https://doi.org/10.1124/mol.60.5.1020
John A. Gray
Departments of 1 2 3 4
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Douglas J. Sheffler
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Anushree Bhatnagar
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Jason A. Woods
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Sandra J. Hufeisen
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Jeffrey L. Benovic
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Bryan L. Roth
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Article Information

vol. 60 no. 5 1020-1030
DOI 
https://doi.org/10.1124/mol.60.5.1020
PubMed 
11641430

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received March 22, 2001
  • Accepted July 25, 2001
  • Published online November 1, 2001.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. John A. Gray1,
  2. Douglas J. Sheffler1,
  3. Anushree Bhatnagar1,
  4. Jason A. Woods1,
  5. Sandra J. Hufeisen1,
  6. Jeffrey L. Benovic4, and
  7. Bryan L. Roth1,2,3
  1. Departments of 1Biochemistry (J.A.G., D.J.S, A.B., J.A.W., S.J.H., B.L.R.), 2Psychiatry (B.L.R.), and 3Neurosciences (B.L.R.), Case Western Reserve University School of Medicine, Cleveland, Ohio and the 4Kimmel Cancer Center (J.L.B.), Thomas Jefferson University Medical School, Philadelphia, Pennsylvania
  1. Dr. Bryan L. Roth, Department of Biochemistry, Room W438, Case Western Reserve University School of Medicine, 10900 Euclid Ave., Cleveland, OH 44106-4935. E-mail:roth{at}biocserver.cwru.edu
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Molecular Pharmacology: 60 (5)
Molecular Pharmacology
Vol. 60, Issue 5
1 Nov 2001
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Cell-Type Specific Effects of Endocytosis Inhibitors on 5-Hydroxytryptamine2A Receptor Desensitization and Resensitization Reveal an Arrestin-, GRK2-, and GRK5-Independent Mode of Regulation in Human Embryonic Kidney 293 Cells
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Research ArticleArticle

Cell-Type Specific Effects of Endocytosis Inhibitors on 5-Hydroxytryptamine2A Receptor Desensitization and Resensitization Reveal an Arrestin-, GRK2-, and GRK5-Independent Mode of Regulation in Human Embryonic Kidney 293 Cells

John A. Gray, Douglas J. Sheffler, Anushree Bhatnagar, Jason A. Woods, Sandra J. Hufeisen, Jeffrey L. Benovic and Bryan L. Roth
Molecular Pharmacology November 1, 2001, 60 (5) 1020-1030; DOI: https://doi.org/10.1124/mol.60.5.1020

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Research ArticleArticle

Cell-Type Specific Effects of Endocytosis Inhibitors on 5-Hydroxytryptamine2A Receptor Desensitization and Resensitization Reveal an Arrestin-, GRK2-, and GRK5-Independent Mode of Regulation in Human Embryonic Kidney 293 Cells

John A. Gray, Douglas J. Sheffler, Anushree Bhatnagar, Jason A. Woods, Sandra J. Hufeisen, Jeffrey L. Benovic and Bryan L. Roth
Molecular Pharmacology November 1, 2001, 60 (5) 1020-1030; DOI: https://doi.org/10.1124/mol.60.5.1020
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