The CYP2D6 Humanized Mouse: Effect of the HumanCYP2D6 Transgene and HNF4α on the Disposition of Debrisoquine in the Mouse

Javier Corchero; Camille P. Granvil; Taro E. Akiyama; Graham P. Hayhurst; Satish Pimprale; Lionel Feigenbaum; Jeffrey R. Idle; Frank J. Gonzalez

doi:10.1124/mol.60.6.1260

Research ArticleArticle

The CYP2D6 Humanized Mouse: Effect of the HumanCYP2D6 Transgene and HNF4α on the Disposition of Debrisoquine in the Mouse

Javier Corchero, Camille P. Granvil, Taro E. Akiyama, Graham P. Hayhurst, Satish Pimprale, Lionel Feigenbaum, Jeffrey R. Idle and Frank J. Gonzalez

Molecular Pharmacology December 2001, 60 (6) 1260-1267; DOI: https://doi.org/10.1124/mol.60.6.1260

Javier Corchero

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Camille P. Granvil

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Taro E. Akiyama

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Graham P. Hayhurst

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Satish Pimprale

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Lionel Feigenbaum

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Jeffrey R. Idle

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Frank J. Gonzalez

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Research ArticleArticle

The CYP2D6 Humanized Mouse: Effect of the HumanCYP2D6 Transgene and HNF4α on the Disposition of Debrisoquine in the Mouse

Javier Corchero, Camille P. Granvil, Taro E. Akiyama, Graham P. Hayhurst, Satish Pimprale, Lionel Feigenbaum, Jeffrey R. Idle and Frank J. Gonzalez

Molecular Pharmacology December 1, 2001, 60 (6) 1260-1267; DOI: https://doi.org/10.1124/mol.60.6.1260

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Research ArticleArticle

The CYP2D6 Humanized Mouse: Effect of the HumanCYP2D6 Transgene and HNF4α on the Disposition of Debrisoquine in the Mouse

Javier Corchero, Camille P. Granvil, Taro E. Akiyama, Graham P. Hayhurst, Satish Pimprale, Lionel Feigenbaum, Jeffrey R. Idle and Frank J. Gonzalez

Molecular Pharmacology December 1, 2001, 60 (6) 1260-1267; DOI: https://doi.org/10.1124/mol.60.6.1260

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