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Midazolam Oxidation by Cytochrome P450 3A4 and Active-Site Mutants: an Evaluation of Multiple Binding Sites and of the Metabolic Pathway That Leads to Enzyme Inactivation

Kishore K. Khan, You Qun He, Tammy L. Domanski and James R. Halpert
Molecular Pharmacology March 2002, 61 (3) 495-506; DOI: https://doi.org/10.1124/mol.61.3.495
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Research ArticleArticle

Midazolam Oxidation by Cytochrome P450 3A4 and Active-Site Mutants: an Evaluation of Multiple Binding Sites and of the Metabolic Pathway That Leads to Enzyme Inactivation

Kishore K. Khan, You Qun He, Tammy L. Domanski and James R. Halpert
Molecular Pharmacology March 1, 2002, 61 (3) 495-506; DOI: https://doi.org/10.1124/mol.61.3.495
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