Table of Contents

Articles

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  p75-Nerve Growth Factor as an Antiapoptotic Complex: Independence versus Cooperativity in Protection from Enediyne Chemotherapeutic Agents

  Chaohua Yan, Ye Liang, Karen D. Nylander, Judith Wong, Rena M. Rudavsky, H. Uri Saragovi and Nina Felice Schor

  Molecular Pharmacology April 2002, 61 (4) 710-719; DOI: https://doi.org/10.1124/mol.61.4.710
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  Identification of a Potent and Selective Pharmacophore for Cdc25 Dual Specificity Phosphatase Inhibitors.

  John S. Lazo, Kaoru Nemoto, Katharine E. Pestell, Kathleen Cooley, Eileen C. Southwick, Douglas A. Mitchell, William Furey, Rick Gussio, Daniel W. Zaharevitz, Beomjun Joo and Peter Wipf

  Molecular Pharmacology April 2002, 61 (4) 720-728; DOI: https://doi.org/10.1124/mol.61.4.720
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  Transport of Amino Acid-Related Compounds Mediated by L-Type Amino Acid Transporter 1 (LAT1): Insights Into the Mechanisms of Substrate Recognition

  Hiroshi Uchino, Yoshikatsu Kanai, Do Kyung Kim, Michael F. Wempe, Arthit Chairoungdua, Emiko Morimoto, M. W. Anders and Hitoshi Endou

  Molecular Pharmacology April 2002, 61 (4) 729-737; DOI: https://doi.org/10.1124/mol.61.4.729
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  Overexpression of the Ubiquitin-Conjugating Enzyme Cdc34 Confers Resistance to Methylmercury in Saccharomyces cerevisiae

  Takemitsu Furuchi, Gi-Wook Hwang and Akira Naganuma

  Molecular Pharmacology April 2002, 61 (4) 738-741; DOI: https://doi.org/10.1124/mol.61.4.738
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  Induction of Biphasic DNA Double Strand Breaks and Activation of Multiple Repair Protein Complexes by DNA Topoisomerase I Drug 7-Ethyl-10-hydroxy-camptothecin

  Jiaxi Wu, Ming-biao Yin, Gunnar Hapke, Károly Tóth and Youcef M. Rustum

  Molecular Pharmacology April 2002, 61 (4) 742-748; DOI: https://doi.org/10.1124/mol.61.4.742
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  Vascular-Targeted Overexpression of G Protein-Coupled Receptor Kinase-2 in Transgenic Mice Attenuates β-Adrenergic Receptor Signaling and Increases Resting Blood Pressure

  Andrea D. Eckhart, Tohru Ozaki, Hendrik Tevaearai, Howard A. Rockman and Walter J. Koch

  Molecular Pharmacology April 2002, 61 (4) 749-758; DOI: https://doi.org/10.1124/mol.61.4.749
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  Side-Chain Substitutions within Angiotensin II Reveal Different Requirements for Signaling, Internalization, and Phosphorylation of Type 1A Angiotensin Receptors

  Alice C. Holloway, Hongwei Qian, Luisa Pipolo, James Ziogas, Shin-ichiro Miura, Sadashiva Karnik, Bridget R. Southwell, Michael J. Lew and Walter G. Thomas

  Molecular Pharmacology April 2002, 61 (4) 768-777; DOI: https://doi.org/10.1124/mol.61.4.768
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  Up-Regulation of Tryptophan Hydroxylase Expression and Serotonin Synthesis by Sertraline

  Seong Who Kim, So Yeon Park and Onyou Hwang

  Molecular Pharmacology April 2002, 61 (4) 778-785; DOI: https://doi.org/10.1124/mol.61.4.778
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  Arachidonic Acid Differentially Affects Basal and Lipopolysaccharide-Induced sPLA₂-IIA Expression in Alveolar Macrophages through NF-κB and PPAR-γ–Dependent Pathways

  Mounia Alaoui-El-Azher, Yongzheng Wu, Nathalie Havet, Alain Israël, Alain Lilienbaum and Lhousseine Touqui

  Molecular Pharmacology April 2002, 61 (4) 786-794; DOI: https://doi.org/10.1124/mol.61.4.786
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  Heterogeneous Nuclear Ribonucleoprotein A1 and Regulation of the Xenobiotic-Inducible Gene Cyp2a5

  Françoise Raffalli-Mathieu, Tina Glisovic, Yaacov Ben-David and Matti A. Lang

  Molecular Pharmacology April 2002, 61 (4) 795-799; DOI: https://doi.org/10.1124/mol.61.4.795
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  Involvement of Activator Protein-1 in Transcriptional Regulation of the Human μ-Opioid Receptor Gene

  Christine Börner, Volker Höllt and Jürgen Kraus

  Molecular Pharmacology April 2002, 61 (4) 800-805; DOI: https://doi.org/10.1124/mol.61.4.800
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  Regulation of Dopamine D₁ Receptor Trafficking by Protein Kinase A-Dependent Phosphorylation

  John N. Mason, Laura B. Kozell and Kim A. Neve

  Molecular Pharmacology April 2002, 61 (4) 806-816; DOI: https://doi.org/10.1124/mol.61.4.806
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  Regulation of Extracellular Signal-Regulated Kinase Cascades by α- and β-Isoforms of the Human Thromboxane A₂ Receptor

  Sinead M. Miggin and B. Therese Kinsella

  Molecular Pharmacology April 2002, 61 (4) 817-831; DOI: https://doi.org/10.1124/mol.61.4.817
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  Induction of Rat Organic Anion Transporting Polypeptide 2 by Pregnenolone-16α-carbonitrile Is via Interaction with Pregnane X Receptor

  Grace L. Guo, Jeff Staudinger, Kenichiro Ogura and Curtis D. Klaassen

  Molecular Pharmacology April 2002, 61 (4) 832-839; DOI: https://doi.org/10.1124/mol.61.4.832
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  Cloning of CYP2J2 Gene and Identification of Functional Polymorphisms

  Lorraine M. King, Jixiang Ma, Supawon Srettabunjong, Joan Graves, J. Alyce Bradbury, Leping Li, Martin Spiecker, James K. Liao, Harvey Mohrenweiser and Darryl C. Zeldin

  Molecular Pharmacology April 2002, 61 (4) 840-852; DOI: https://doi.org/10.1124/mol.61.4.840
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  Carriers Involved in Targeting the Cytostatic Bile Acid-Cisplatin Derivativescis-Diammine-chloro-cholylglycinate-platinum(II) andcis-Diammine-bisursodeoxycholate-platinum(II) toward Liver Cells

  Oscar Briz, Maria Angeles Serrano, Noemi Rebollo, Bruno Hagenbuch, Peter J. Meier, Hermann Koepsell and Jose J.G. Marin

  Molecular Pharmacology April 2002, 61 (4) 853-860; DOI: https://doi.org/10.1124/mol.61.4.853
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  Tracazolate Reveals a Novel Type of Allosteric Interaction with Recombinant γ-Aminobutyric Acid_A Receptors

  Sally-Anne Thompson, Peter B. Wingrove, Linda Connelly, Paul J. Whiting and Keith A. Wafford

  Molecular Pharmacology April 2002, 61 (4) 861-869; DOI: https://doi.org/10.1124/mol.61.4.861
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  Delayed Formation of Hydrogen Peroxide Mediates the Lethal Response Evoked by Peroxynitrite in U937 Cells

  Ilaria Tommasini, Piero Sestili and Orazio Cantoni

  Molecular Pharmacology April 2002, 61 (4) 870-878; DOI: https://doi.org/10.1124/mol.61.4.870
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  Down-Regulation of DNA Topoisomerase IIα in Human Colorectal Carcinoma Cells Resistant to a Protoberberine Alkaloid, Berberrubine

  Mi Ran Kang and In Kwon Chung

  Molecular Pharmacology April 2002, 61 (4) 879-884; DOI: https://doi.org/10.1124/mol.61.4.879
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  Dopamine Transporter Mutants with Cocaine Resistance and Normal Dopamine Uptake Provide Targets for Cocaine Antagonism

  Zhicheng Lin and George R. Uhl

  Molecular Pharmacology April 2002, 61 (4) 885-891; DOI: https://doi.org/10.1124/mol.61.4.885
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  Cytochrome P450 3A Conjugation to Ubiquitin in a Process Distinct from Classical Ubiquitination Pathway

  R. C. Zangar, A. L. Kimzey, J. R. Okita, D. S. Wunschel, R. J. Edwards, H. Kim and R. T. Okita

  Molecular Pharmacology April 2002, 61 (4) 892-904; DOI: https://doi.org/10.1124/mol.61.4.892
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  The Batrachotoxin Receptor on the Voltage-Gated Sodium Channel is Guarded by the Channel Activation Gate

  Hong-Ling Li, David Hadid and David S. Ragsdale

  Molecular Pharmacology April 2002, 61 (4) 905-912; DOI: https://doi.org/10.1124/mol.61.4.905
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  Determinants of 4-Aminopyridine Sensitivity in a Human Brain Kv1.4 K⁺ Channel: Phenylalanine Substitutions in Leucine Heptad Repeat Region Stabilize Channel Closed State

  Susan I. V. Judge, Jay Z. Yeh, James E. Goolsby, Mervyn J. Monteiro and Christopher T. Bever

  Molecular Pharmacology April 2002, 61 (4) 913-920; DOI: https://doi.org/10.1124/mol.61.4.913
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  Effects of the Anticonvulsant Retigabine on Cultured Cortical Neurons: Changes in Electroresponsive Properties and Synaptic Transmission

  James F. Otto, Matthew M. Kimball and Karen S. Wilcox

  Molecular Pharmacology April 2002, 61 (4) 921-927; DOI: https://doi.org/10.1124/mol.61.4.921
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  Functional Expression of a Novel Ginsenoside Rf Binding Protein from Rat Brain mRNA in Xenopus laevis Oocytes

  Seok Choi, Se-Yeon Jung, Yoo-Seung Ko, Seong-Ryong Koh, Hyewhon Rhim and Seung-Yeol Nah

  Molecular Pharmacology April 2002, 61 (4) 928-935; DOI: https://doi.org/10.1124/mol.61.4.928
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  The Virally Encoded Fungal Toxin KP4 Specifically Blocks L-Type Voltage-Gated Calcium Channels

  Matthew J. Gage, Stanley G. Rane, Gregory H. Hockerman and Thomas J. Smith

  Molecular Pharmacology April 2002, 61 (4) 936-944; DOI: https://doi.org/10.1124/mol.61.4.936