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Molecular Pharmacology

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Table of Contents

April 01, 2002; Volume 61,Issue 4

Perspective

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    Deactivation of Vasodilator Responses by GRK2 Overexpression:A Mechanism or the Mechanism for Hypertension?
    Ross D. Feldman
    Molecular Pharmacology April 2002, 61 (4) 707-709; DOI: https://doi.org/10.1124/mol.61.4.707

Articles

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    p75-Nerve Growth Factor as an Antiapoptotic Complex: Independence versus Cooperativity in Protection from Enediyne Chemotherapeutic Agents
    Chaohua Yan, Ye Liang, Karen D. Nylander, Judith Wong, Rena M. Rudavsky, H. Uri Saragovi and Nina Felice Schor
    Molecular Pharmacology April 2002, 61 (4) 710-719; DOI: https://doi.org/10.1124/mol.61.4.710
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    Identification of a Potent and Selective Pharmacophore for Cdc25 Dual Specificity Phosphatase Inhibitors.
    John S. Lazo, Kaoru Nemoto, Katharine E. Pestell, Kathleen Cooley, Eileen C. Southwick, Douglas A. Mitchell, William Furey, Rick Gussio, Daniel W. Zaharevitz, Beomjun Joo and Peter Wipf
    Molecular Pharmacology April 2002, 61 (4) 720-728; DOI: https://doi.org/10.1124/mol.61.4.720
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    Transport of Amino Acid-Related Compounds Mediated by L-Type Amino Acid Transporter 1 (LAT1): Insights Into the Mechanisms of Substrate Recognition
    Hiroshi Uchino, Yoshikatsu Kanai, Do Kyung Kim, Michael F. Wempe, Arthit Chairoungdua, Emiko Morimoto, M. W. Anders and Hitoshi Endou
    Molecular Pharmacology April 2002, 61 (4) 729-737; DOI: https://doi.org/10.1124/mol.61.4.729
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    Overexpression of the Ubiquitin-Conjugating Enzyme Cdc34 Confers Resistance to Methylmercury in Saccharomyces cerevisiae
    Takemitsu Furuchi, Gi-Wook Hwang and Akira Naganuma
    Molecular Pharmacology April 2002, 61 (4) 738-741; DOI: https://doi.org/10.1124/mol.61.4.738
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    Induction of Biphasic DNA Double Strand Breaks and Activation of Multiple Repair Protein Complexes by DNA Topoisomerase I Drug 7-Ethyl-10-hydroxy-camptothecin
    Jiaxi Wu, Ming-biao Yin, Gunnar Hapke, Károly Tóth and Youcef M. Rustum
    Molecular Pharmacology April 2002, 61 (4) 742-748; DOI: https://doi.org/10.1124/mol.61.4.742
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    Vascular-Targeted Overexpression of G Protein-Coupled Receptor Kinase-2 in Transgenic Mice Attenuates β-Adrenergic Receptor Signaling and Increases Resting Blood Pressure
    Andrea D. Eckhart, Tohru Ozaki, Hendrik Tevaearai, Howard A. Rockman and Walter J. Koch
    Molecular Pharmacology April 2002, 61 (4) 749-758; DOI: https://doi.org/10.1124/mol.61.4.749
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    Side-Chain Substitutions within Angiotensin II Reveal Different Requirements for Signaling, Internalization, and Phosphorylation of Type 1A Angiotensin Receptors
    Alice C. Holloway, Hongwei Qian, Luisa Pipolo, James Ziogas, Shin-ichiro Miura, Sadashiva Karnik, Bridget R. Southwell, Michael J. Lew and Walter G. Thomas
    Molecular Pharmacology April 2002, 61 (4) 768-777; DOI: https://doi.org/10.1124/mol.61.4.768
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    Up-Regulation of Tryptophan Hydroxylase Expression and Serotonin Synthesis by Sertraline
    Seong Who Kim, So Yeon Park and Onyou Hwang
    Molecular Pharmacology April 2002, 61 (4) 778-785; DOI: https://doi.org/10.1124/mol.61.4.778
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    Arachidonic Acid Differentially Affects Basal and Lipopolysaccharide-Induced sPLA2-IIA Expression in Alveolar Macrophages through NF-κB and PPAR-γ–Dependent Pathways
    Mounia Alaoui-El-Azher, Yongzheng Wu, Nathalie Havet, Alain Israël, Alain Lilienbaum and Lhousseine Touqui
    Molecular Pharmacology April 2002, 61 (4) 786-794; DOI: https://doi.org/10.1124/mol.61.4.786
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    Heterogeneous Nuclear Ribonucleoprotein A1 and Regulation of the Xenobiotic-Inducible Gene Cyp2a5
    Françoise Raffalli-Mathieu, Tina Glisovic, Yaacov Ben-David and Matti A. Lang
    Molecular Pharmacology April 2002, 61 (4) 795-799; DOI: https://doi.org/10.1124/mol.61.4.795
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    Involvement of Activator Protein-1 in Transcriptional Regulation of the Human μ-Opioid Receptor Gene
    Christine Börner, Volker Höllt and Jürgen Kraus
    Molecular Pharmacology April 2002, 61 (4) 800-805; DOI: https://doi.org/10.1124/mol.61.4.800
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    Regulation of Dopamine D1 Receptor Trafficking by Protein Kinase A-Dependent Phosphorylation
    John N. Mason, Laura B. Kozell and Kim A. Neve
    Molecular Pharmacology April 2002, 61 (4) 806-816; DOI: https://doi.org/10.1124/mol.61.4.806
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    Regulation of Extracellular Signal-Regulated Kinase Cascades by α- and β-Isoforms of the Human Thromboxane A2 Receptor
    Sinead M. Miggin and B. Therese Kinsella
    Molecular Pharmacology April 2002, 61 (4) 817-831; DOI: https://doi.org/10.1124/mol.61.4.817
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    Induction of Rat Organic Anion Transporting Polypeptide 2 by Pregnenolone-16α-carbonitrile Is via Interaction with Pregnane X Receptor
    Grace L. Guo, Jeff Staudinger, Kenichiro Ogura and Curtis D. Klaassen
    Molecular Pharmacology April 2002, 61 (4) 832-839; DOI: https://doi.org/10.1124/mol.61.4.832
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    Cloning of CYP2J2 Gene and Identification of Functional Polymorphisms
    Lorraine M. King, Jixiang Ma, Supawon Srettabunjong, Joan Graves, J. Alyce Bradbury, Leping Li, Martin Spiecker, James K. Liao, Harvey Mohrenweiser and Darryl C. Zeldin
    Molecular Pharmacology April 2002, 61 (4) 840-852; DOI: https://doi.org/10.1124/mol.61.4.840
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    Carriers Involved in Targeting the Cytostatic Bile Acid-Cisplatin Derivativescis-Diammine-chloro-cholylglycinate-platinum(II) andcis-Diammine-bisursodeoxycholate-platinum(II) toward Liver Cells
    Oscar Briz, Maria Angeles Serrano, Noemi Rebollo, Bruno Hagenbuch, Peter J. Meier, Hermann Koepsell and Jose J.G. Marin
    Molecular Pharmacology April 2002, 61 (4) 853-860; DOI: https://doi.org/10.1124/mol.61.4.853
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    Tracazolate Reveals a Novel Type of Allosteric Interaction with Recombinant γ-Aminobutyric AcidA Receptors
    Sally-Anne Thompson, Peter B. Wingrove, Linda Connelly, Paul J. Whiting and Keith A. Wafford
    Molecular Pharmacology April 2002, 61 (4) 861-869; DOI: https://doi.org/10.1124/mol.61.4.861
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    Delayed Formation of Hydrogen Peroxide Mediates the Lethal Response Evoked by Peroxynitrite in U937 Cells
    Ilaria Tommasini, Piero Sestili and Orazio Cantoni
    Molecular Pharmacology April 2002, 61 (4) 870-878; DOI: https://doi.org/10.1124/mol.61.4.870
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    Down-Regulation of DNA Topoisomerase IIα in Human Colorectal Carcinoma Cells Resistant to a Protoberberine Alkaloid, Berberrubine
    Mi Ran Kang and In Kwon Chung
    Molecular Pharmacology April 2002, 61 (4) 879-884; DOI: https://doi.org/10.1124/mol.61.4.879
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    Dopamine Transporter Mutants with Cocaine Resistance and Normal Dopamine Uptake Provide Targets for Cocaine Antagonism
    Zhicheng Lin and George R. Uhl
    Molecular Pharmacology April 2002, 61 (4) 885-891; DOI: https://doi.org/10.1124/mol.61.4.885
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    Cytochrome P450 3A Conjugation to Ubiquitin in a Process Distinct from Classical Ubiquitination Pathway
    R. C. Zangar, A. L. Kimzey, J. R. Okita, D. S. Wunschel, R. J. Edwards, H. Kim and R. T. Okita
    Molecular Pharmacology April 2002, 61 (4) 892-904; DOI: https://doi.org/10.1124/mol.61.4.892
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    The Batrachotoxin Receptor on the Voltage-Gated Sodium Channel is Guarded by the Channel Activation Gate
    Hong-Ling Li, David Hadid and David S. Ragsdale
    Molecular Pharmacology April 2002, 61 (4) 905-912; DOI: https://doi.org/10.1124/mol.61.4.905
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    Determinants of 4-Aminopyridine Sensitivity in a Human Brain Kv1.4 K+ Channel: Phenylalanine Substitutions in Leucine Heptad Repeat Region Stabilize Channel Closed State
    Susan I. V. Judge, Jay Z. Yeh, James E. Goolsby, Mervyn J. Monteiro and Christopher T. Bever
    Molecular Pharmacology April 2002, 61 (4) 913-920; DOI: https://doi.org/10.1124/mol.61.4.913
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    Effects of the Anticonvulsant Retigabine on Cultured Cortical Neurons: Changes in Electroresponsive Properties and Synaptic Transmission
    James F. Otto, Matthew M. Kimball and Karen S. Wilcox
    Molecular Pharmacology April 2002, 61 (4) 921-927; DOI: https://doi.org/10.1124/mol.61.4.921
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    Functional Expression of a Novel Ginsenoside Rf Binding Protein from Rat Brain mRNA in Xenopus laevis Oocytes
    Seok Choi, Se-Yeon Jung, Yoo-Seung Ko, Seong-Ryong Koh, Hyewhon Rhim and Seung-Yeol Nah
    Molecular Pharmacology April 2002, 61 (4) 928-935; DOI: https://doi.org/10.1124/mol.61.4.928
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    The Virally Encoded Fungal Toxin KP4 Specifically Blocks L-Type Voltage-Gated Calcium Channels
    Matthew J. Gage, Stanley G. Rane, Gregory H. Hockerman and Thomas J. Smith
    Molecular Pharmacology April 2002, 61 (4) 936-944; DOI: https://doi.org/10.1124/mol.61.4.936

MINIREVIEW

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    Novel “Nonkinase” Phorbol Ester Receptors: The C1 Domain Connection
    Marcelo G. Kazanietz
    Molecular Pharmacology April 2002, 61 (4) 759-767; DOI: https://doi.org/10.1124/mol.61.4.759
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Molecular Pharmacology: 61 (4)
Molecular Pharmacology
Vol. 61, Issue 4
1 Apr 2002
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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