Native CYP2C11: Heterologous Expression in Saccharomyces cerevisiae Reveals a Role for Vacuolar Proteases Rather Than the Proteasome System in the Degradation of This Endoplasmic Reticulum Protein

Departments of Cellular and Molecular Pharmacology, Pharmaceutical Chemistry, and Biopharmaceutical Sciences and the Liver Center, University of California, San Francisco, California

Dr. M. A. Correia, Department of Cellular and Molecular Pharmacology, Box 0450, University of California, San Francisco, San Francisco, CA 94143-0450. E-mail:mariac{at}itsa.ucsf.edu

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	Abstract	Full	Pdf
Apr 2002	20	43	43
May 2002	2	35	23
Jun 2002	2	17	17
Jul 2002	4	21	17
Aug 2002	2	8	8
Sep 2002	4	16	14
Oct 2002	2	16	9
Nov 2002	0	3	1
Dec 2002	0	10	7
Jan 2003	4	12	7
Feb 2003	0	9	7
Mar 2003	3	7	2
Apr 2003	2	15	12
May 2003	1	12	12
Jun 2003	1	7	4
Jul 2003	9	23	6
Aug 2003	7	17	5
Sep 2003	11	20	7
Oct 2003	7	21	16
Nov 2003	14	25	5
Dec 2003	16	14	5
Jan 2004	9	25	12
Feb 2004	2	32	10
Mar 2004	16	38	5
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May 2004	8	26	8
Jun 2004	8	37	9
Jul 2004	22	60	12
Aug 2004	12	43	7
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Oct 2004	11	19	6
Nov 2004	8	17	8
Dec 2004	12	31	9
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Feb 2005	8	27	14
Mar 2005	10	17	3
Apr 2005	3	19	5
May 2005	5	20	9
Jun 2005	6	33	10
Jul 2005	3	18	4
Aug 2005	6	23	4
Sep 2005	10	14	8
Oct 2005	3	27	3
Nov 2005	7	20	3
Dec 2005	5	15	2
Jan 2006	12	32	7
Feb 2006	7	30	11
Mar 2006	2	22	0
Apr 2006	1	34	13
May 2006	1	27	6
Jun 2006	3	19	5
Jul 2006	2	27	2
Aug 2006	1	15	3
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Oct 2006	5	47	1
Nov 2006	2	21	2
Dec 2006	2	15	3
Jan 2007	3	10	3
Feb 2007	5	9	2
Mar 2007	2	14	6
Apr 2007	6	17	6
May 2007	7	29	3
Jun 2007	5	11	2
Jul 2007	4	15	5
Aug 2007	4	9	4
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Oct 2007	3	7	3
Nov 2007	6	22	12
Dec 2007	2	14	5
Jan 2008	3	10	8
Feb 2008	1	15	8
Mar 2008	11	14	6
Apr 2008	16	15	6
May 2008	6	11	6
Jun 2008	10	18	10
Jul 2008	18	14	7
Aug 2008	27	22	4
Sep 2008	10	8	2
Oct 2008	11	15	2
Nov 2008	23	9	7
Dec 2008	3	6	2
Jan 2009	4	16	4
Feb 2009	5	25	5
Mar 2009	21	27	3
Apr 2009	7	22	5
May 2009	9	17	4
Jun 2009	5	9	1
Jul 2009	10	17	3
Aug 2009	4	11	1
Sep 2009	8	12	1
Oct 2009	23	14	1
Nov 2009	10	17	0
Dec 2009	28	6	1
Jan 2010	5	5	6
Feb 2010	7	0	3
Mar 2010	3	4	3
Apr 2010	11	3	2
May 2010	1	9	5
Jun 2010	6	6	4
Jul 2010	6	4	4
Aug 2010	3	1	4
Sep 2010	11	3	3
Oct 2010	8	3	3
Nov 2010	3	5	4
Dec 2010	6	10	3
Jan 2011	6	7	6
Feb 2011	8	5	1
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Apr 2011	10	7	4
May 2011	6	4	5
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Aug 2011	5	5	4
Sep 2011	17	5	7
Oct 2011	10	13	6
Nov 2011	8	7	7
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Oct 2012	4	1	4
Nov 2012	7	5	3
Dec 2012	5	5	8
Jan 2013	22	16	7
Feb 2013	9	3	2
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Apr 2013	10	2	7
May 2013	9	8	4
Jun 2013	4	1	2
Jul 2013	5	0	4
Aug 2013	0	0	3
Sep 2013	2	0	2
Oct 2013	4	3	2
Nov 2013	6	4	5
Dec 2013	6	3	4
Jan 2014	5	2	4
Feb 2014	3	2	6
Mar 2014	4	1	0
Apr 2014	4	1	4
May 2014	11	2	8
Jun 2014	5	0	0
Jul 2014	7	3	6
Aug 2014	5	2	6
Sep 2014	1	5	4
Oct 2014	8	5	1
Nov 2014	11	5	0
Dec 2014	2	7	2
Jan 2015	4	5	2
Feb 2015	1	0	11
Mar 2015	7	2	5
Apr 2015	5	6	3
May 2015	5	10	3
Jun 2015	5	3	2
Jul 2015	8	11	9
Aug 2015	5	9	2
Sep 2015	2	4	6
Oct 2015	0	1	0
Nov 2015	5	2	2
Dec 2015	3	1	3
Jan 2016	3	4	0
Feb 2016	8	5	1
Mar 2016	10	0	4
Apr 2016	2	1	2
May 2016	5	6	3
Jun 2016	4	6	3
Jul 2016	4	9	4
Aug 2016	2	6	1
Sep 2016	2	5	1
Oct 2016	0	8	0
Nov 2016	0	4	3
Dec 2016	0	9	1
Jan 2017	0	5	0
Feb 2017	1	6	1
Mar 2017	1	5	1
Apr 2017	0	6	3
May 2017	0	3	0
Jun 2017	0	6	1
Jul 2017	0	6	0
Aug 2017	0	8	1
Sep 2017	0	8	1
Oct 2017	0	9	1
Nov 2017	0	7	1
Dec 2017	0	7	1
Jan 2018	0	8	0
Feb 2018	1	4	0
Mar 2018	1	4	0
Apr 2018	1	18	0
May 2018	0	9	3
Jun 2018	5	4	2
Jul 2018	0	4	1
Aug 2018	0	5	0
Sep 2018	0	4	1
Oct 2018	0	5	4
Nov 2018	0	2	2
Dec 2018	8	1	0
Jan 2019	10	0	0
Feb 2019	9	0	0
Mar 2019	10	2	1
Apr 2019	10	0	0
May 2019	8	4	1
Jun 2019	11	0	2
Jul 2019	12	0	0
Aug 2019	10	0	0
Sep 2019	12	0	0
Oct 2019	6	0	0
Nov 2019	8	0	0
Dec 2019	10	0	0
Jan 2020	10	0	0
Feb 2020	6	0	0
Mar 2020	8	0	0
Apr 2020	7	0	0
May 2020	11	0	0
Jun 2020	19	0	0
Jul 2020	14	0	0
Aug 2020	0	0	1
Sep 2020	1	0	0
Oct 2020	30	1	0
Nov 2020	7	0	0
Dec 2020	14	0	0
Jan 2021	11	4	1
Feb 2021	5	1	0
Mar 2021	9	1	0
Apr 2021	25	0	0