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Research ArticleArticle

A G-Quadruplex-Interactive Potent Small-Molecule Inhibitor of Telomerase Exhibiting in Vitro and in Vivo Antitumor Activity

Sharon M. Gowan, John R. Harrison, Lisa Patterson, Melanie Valenti, Martin A. Read, Stephen Neidle and Lloyd R. Kelland
Molecular Pharmacology May 2002, 61 (5) 1154-1162; DOI: https://doi.org/10.1124/mol.61.5.1154
Sharon M. Gowan
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John R. Harrison
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Lisa Patterson
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Melanie Valenti
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Martin A. Read
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Stephen Neidle
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Lloyd R. Kelland
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Article Information

vol. 61 no. 5 1154-1162
DOI 
https://doi.org/10.1124/mol.61.5.1154
PubMed 
11961134

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received October 30, 2001
  • Accepted February 6, 2002
  • Published online May 1, 2002.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Sharon M. Gowan1,
  2. John R. Harrison2,
  3. Lisa Patterson1,
  4. Melanie Valenti1,
  5. Martin A. Read2,
  6. Stephen Neidle2, and
  7. Lloyd R. Kelland1
  1. 1Cancer Research Campaign (CRC) Center for Cancer Therapeutics, Institute of Cancer Research, Surrey, United Kingdom (S.M.G., L.P., M.V., L.R.K.); and 2CRC Biomolecular Structure Unit, Chester Beatty Laboratories, Institute of Cancer Research, London, United Kingdom (J.R.H., M.A.R., S.N.)
  1. Lloyd R. Kelland, Antisoma plc, St. George's Hospital Medical School, Cranmer Terrace, London SW17 OQS, UK. E-mail: lloyd{at}antisoma.com
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Molecular Pharmacology: 61 (5)
Molecular Pharmacology
Vol. 61, Issue 5
1 May 2002
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Research ArticleArticle

A G-Quadruplex-Interactive Potent Small-Molecule Inhibitor of Telomerase Exhibiting in Vitro and in Vivo Antitumor Activity

Sharon M. Gowan, John R. Harrison, Lisa Patterson, Melanie Valenti, Martin A. Read, Stephen Neidle and Lloyd R. Kelland
Molecular Pharmacology May 1, 2002, 61 (5) 1154-1162; DOI: https://doi.org/10.1124/mol.61.5.1154

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Research ArticleArticle

A G-Quadruplex-Interactive Potent Small-Molecule Inhibitor of Telomerase Exhibiting in Vitro and in Vivo Antitumor Activity

Sharon M. Gowan, John R. Harrison, Lisa Patterson, Melanie Valenti, Martin A. Read, Stephen Neidle and Lloyd R. Kelland
Molecular Pharmacology May 1, 2002, 61 (5) 1154-1162; DOI: https://doi.org/10.1124/mol.61.5.1154
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