Table of Contents

Articles

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  pS2 Gene Expression in HepG2 cells: Complex Regulation through Crosstalk between the Estrogen Receptor α, an Estrogen-Responsive Element, and the Activator Protein 1 Response Element

  Tomas Barkhem, Lars-Arne Haldosén, Jan-Åke Gustafsson and Stefan Nilsson

  Molecular Pharmacology June 2002, 61 (6) 1273-1283; DOI: https://doi.org/10.1124/mol.61.6.1273
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  Residue Threonine 350 Confers Steroid Hormone Responsiveness to the Mouse Nuclear Orphan Receptor CAR

  Akiko Ueda, Satoru Kakizaki, Masahiko Negishi and Tatsuya Sueyoshi

  Molecular Pharmacology June 2002, 61 (6) 1284-1288; DOI: https://doi.org/10.1124/mol.61.6.1284
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  ATA2 Is Predominantly Expressed as System A at the Blood-Brain Barrier and Acts as Brain-to-Blood Efflux Transport forl-Proline

  Hitomi Takanaga, Noriyo Tokuda, Sumio Ohtsuki, Ken-ichi Hosoya and Tetsuya Terasaki

  Molecular Pharmacology June 2002, 61 (6) 1289-1296; DOI: https://doi.org/10.1124/mol.61.6.1289
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  Discovery of an Ectopic Activation Site on the M₁Muscarinic Receptor

  Tracy A. Spalding, Carol Trotter, Niels Skjærbæk, Terri L. Messier, Erika A. Currier, Ethan S. Burstein, Donghui Li, Uli Hacksell and Mark R. Brann

  Molecular Pharmacology June 2002, 61 (6) 1297-1302; DOI: https://doi.org/10.1124/mol.61.6.1297
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  Dissociation of Protein Kinase-Mediated Regulation of Metabotropic Glutamate Receptor 7 (mGluR7) Interactions with Calmodulin and Regulation of mGluR7 Function

  Scott D. Sorensen, Thomas A. Macek, Zhaohui Cai, Julie A. Saugstad and P. Jeffrey Conn

  Molecular Pharmacology June 2002, 61 (6) 1303-1312; DOI: https://doi.org/10.1124/mol.61.6.1303
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  Synergistic Induction of Apoptosis in Human Myeloid Leukemia Cells by Phorbol 12-Myristate 13-Acetate and Flavopiridol Proceeds via Activation of Both the Intrinsic and Tumor Necrosis Factor-Mediated Extrinsic Cell Death Pathways

  L. Cartee, R. Smith, Y. Dai, M. Rahmani, R. Rosato, J. Almenara, P. Dent and S. Grant

  Molecular Pharmacology June 2002, 61 (6) 1313-1321; DOI: https://doi.org/10.1124/mol.61.6.1313
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  Amiloride Inhibition of γ-Aminobutyric Acid_AReceptors Depends upon the α Subunit Subtype

  Janet L. Fisher

  Molecular Pharmacology June 2002, 61 (6) 1322-1328; DOI: https://doi.org/10.1124/mol.61.6.1322
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  Ca²⁺-Mobilizing Endothelin-A Receptors Inhibit Voltage-Gated Ca²⁺ Influx through G_i/oSignaling Pathway in Pituitary Lactotrophs

  Melanija Tomić, Fredrick Van Goor, Mu-Lan He, Dragoslava Zivadinovic and Stanko S. Stojilkovic

  Molecular Pharmacology June 2002, 61 (6) 1329-1339; DOI: https://doi.org/10.1124/mol.61.6.1329
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  Chromaffin Cell Catecholamine Secretion: Bisindolylmaleimide Compounds Exhibit Novel and Potent Antagonist Effects at the Nicotinic Cholinergic Receptor in Pheochromocytoma Cells

  Manjula Mahata, Nitish R. Mahapatra, Daniel T. O'Connor and Sushil K. Mahata

  Molecular Pharmacology June 2002, 61 (6) 1340-1347; DOI: https://doi.org/10.1124/mol.61.6.1340
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  A Novel β-Lactam Antibiotic Activates Tumor Cell Apoptotic Program by Inducing DNA Damage

  David M. Smith, Aslamuzzaman Kazi, Lisa Smith, Timothy E. Long, Bart Heldreth, Edward Turos and Q. Ping Dou

  Molecular Pharmacology June 2002, 61 (6) 1348-1358; DOI: https://doi.org/10.1124/mol.61.6.1348
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  Inhibition of the Tax-Dependent Human T-Lymphotropic Virus Type I Replication in Persistently Infected Cells by the Fluoroquinolone Derivative K-37

  Xin Wang, Hiroshi Miyake, Mika Okamoto, Mineki Saito, Jun-Ichi Fujisawa, Yuetsu Tanaka, Shuji Izumo and Masanori Baba

  Molecular Pharmacology June 2002, 61 (6) 1359-1365; DOI: https://doi.org/10.1124/mol.61.6.1359
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  Characterization of the Dexniguldipine Binding Site in the Multidrug Resistance-Related Transport Protein P-Glycoprotein by Photoaffinity Labeling and Mass Spectrometry

  Christoph Borchers, Rainer Boer, Kurt Klemm, Volker Figala, Thomas Denzinger, Wolf-Rüdiger Ulrich, Sabine Haas, Wolfgang Ise, Volker Gekeler and Michael Przybylski

  Molecular Pharmacology June 2002, 61 (6) 1366-1376; DOI: https://doi.org/10.1124/mol.61.6.1366
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  The Anticonvulsant Gabapentin (Neurontin) Does Not Act through γ-Aminobutyric Acid-B Receptors

  Anders A. Jensen, Johannes Mosbacher, Susanne Elg, Kurt Lingenhoehl, Tania Lohmann, Tommy N. Johansen, Bjarke Abrahamsen, Jan P. Mattsson, Anders Lehmann, Bernhard Bettler and Hans Bräuner-Osborne

  Molecular Pharmacology June 2002, 61 (6) 1377-1384; DOI: https://doi.org/10.1124/mol.61.6.1377
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  Glucocorticoid Responsiveness of the Rat PhenylethanolamineN-Methyltransferase Gene

  T. C. Tai, R. Claycomb, S. Her, A. K. Bloom and Dona L. Wong

  Molecular Pharmacology June 2002, 61 (6) 1385-1392; DOI: https://doi.org/10.1124/mol.61.6.1385
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  Analysis of the Antiestrogenic Activity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Human Ovarian Carcinoma BG-1 Cells

  Jane M. Rogers and Michael S. Denison

  Molecular Pharmacology June 2002, 61 (6) 1393-1403; DOI: https://doi.org/10.1124/mol.61.6.1393
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  Site-Directed Mutagenesis of the Gerbil and Human Angiotensin II AT₁ Receptors Identifies Amino Acid Residues Attributable to the Binding Affinity for the Nonpeptidic Antagonist Losartan

  Kwang-Lae Hoe and Juan M. Saavedra

  Molecular Pharmacology June 2002, 61 (6) 1404-1415; DOI: https://doi.org/10.1124/mol.61.6.1404
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  First and Second Transmembrane Segments of α3, α4, β2, and β4 Nicotinic Acetylcholine Receptor Subunits Influence the Efficacy and Potency of Nicotine

  Ray Rush, Alexander Kuryatov, Mark E. Nelson and Jon Lindstrom

  Molecular Pharmacology June 2002, 61 (6) 1416-1422; DOI: https://doi.org/10.1124/mol.61.6.1416
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  The Muscarinic Acetylcholine Receptor-Stimulated Increase in Aquaporin-5 Levels in the Apical Plasma Membrane in Rat Parotid Acinar Cells Is Coupled with Activation of Nitric Oxide/cGMP Signal Transduction

  Yasuko Ishikawa, Hirokazu Iida and Hajime Ishida

  Molecular Pharmacology June 2002, 61 (6) 1423-1434; DOI: https://doi.org/10.1124/mol.61.6.1423
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  Molecular Basis of the Selectivity of Gastrin-Releasing Peptide Receptor for Gastrin-Releasing Peptide

  Kenji Tokita, Simon J. Hocart, David H. Coy and Robert T. Jensen

  Molecular Pharmacology June 2002, 61 (6) 1435-1443; DOI: https://doi.org/10.1124/mol.61.6.1435
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  Visualizing Preference of G Protein-Coupled Receptor Kinase 3 for the Process of κ-Opioid Receptor Sequestration

  Rüdiger Schulz, Andrea Wehmeyer and Karin Schulz

  Molecular Pharmacology June 2002, 61 (6) 1444-1452; DOI: https://doi.org/10.1124/mol.61.6.1444
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  Inducible and Brain Region-Specific CREB Transgenic Mice

  Norio Sakai, Johannes Thome, Samuel S. Newton, Jingshan Chen, Max B. Kelz, Cathy Steffen, Eric J. Nestler and Ronald S. Duman

  Molecular Pharmacology June 2002, 61 (6) 1453-1464; DOI: https://doi.org/10.1124/mol.61.6.1453
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  Proteochemometrics Modeling of the Interaction of Amine G-Protein Coupled Receptors with a Diverse Set of Ligands

  Maris Lapinsh, Peteris Prusis, Torbjörn Lundstedt and Jarl E. S. Wikberg

  Molecular Pharmacology June 2002, 61 (6) 1465-1475; DOI: https://doi.org/10.1124/mol.61.6.1465
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  Selective Down-Regulation of c-jun Gene Expression by Pentoxifylline and c-jun Antisense Interrupts Platelet-Derived Growth Factor Signaling: Pentoxifylline Inhibits Phosphorylation of c-Jun on Serine 73

  Theresa C. Peterson, Marc R. Peterson, Harold A. Robertson, Matthew During and Michael Dragunow

  Molecular Pharmacology June 2002, 61 (6) 1476-1488; DOI: https://doi.org/10.1124/mol.61.6.1476
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  Inhibition of c-Abl with STI571 Attenuates Stress-Activated Protein Kinase Activation and Apoptosis in the Cellular Response to 1-β-d-Arabinofuranosylcytosine

  Deepak Raina, Neerad Mishra, Shailendra Kumar, Surender Kharbanda, Satya Saxena and Donald Kufe

  Molecular Pharmacology June 2002, 61 (6) 1489-1495; DOI: https://doi.org/10.1124/mol.61.6.1489