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Research ArticleArticle

Inhibition of Transforming Growth Factor (TGF)-β1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF-β Type I Receptor Kinase Activity: SB-431542

N. J. Laping, E. Grygielko, A. Mathur, S. Butter, J. Bomberger, C. Tweed, W. Martin, J. Fornwald, R. Lehr, J. Harling, L. Gaster, J. F. Callahan and B. A. Olson
Molecular Pharmacology July 2002, 62 (1) 58-64; DOI: https://doi.org/10.1124/mol.62.1.58
N. J. Laping
Departments of 1 2 3 4
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E. Grygielko
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A. Mathur
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S. Butter
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J. Bomberger
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C. Tweed
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W. Martin
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J. Fornwald
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R. Lehr
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J. Harling
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L. Gaster
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J. F. Callahan
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B. A. Olson
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Article Information

vol. 62 no. 1 58-64
DOI 
https://doi.org/10.1124/mol.62.1.58
PubMed 
12065755

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received November 28, 2001
  • Accepted March 21, 2002
  • Published online July 1, 2002.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. N. J. Laping1,
  2. E. Grygielko1,
  3. A. Mathur1,
  4. S. Butter1,
  5. J. Bomberger1,
  6. C. Tweed1,
  7. W. Martin1,
  8. J. Fornwald2,
  9. R. Lehr3,
  10. J. Harling4,
  11. L. Gaster4,
  12. J. F. Callahan4, and
  13. B. A. Olson1
  1. Departments of 1Renal and Urology Research (N.J.L., E.G., A.M., S.B., J.B., C.T., W.M., B.A.O.), 2Gene Expression Sciences (J.F.), 3Protein Biochemistry (R.L.), and 4Medicinal Chemistry (J.H., L.G., J.F.C.), GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania
  1. Nicholas J. Laping, Ph.D., Renal and Urology Research, UW2521, GlaxoSmithKline Pharmaceuticals, 709 Swedeland Road, P.O. Box 1539, King of Prussia, PA 19406. E-mail:nicholas_j_laping{at}sbphrd.com
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Molecular Pharmacology: 62 (1)
Molecular Pharmacology
Vol. 62, Issue 1
1 Jul 2002
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Research ArticleArticle

Inhibition of Transforming Growth Factor (TGF)-β1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF-β Type I Receptor Kinase Activity: SB-431542

N. J. Laping, E. Grygielko, A. Mathur, S. Butter, J. Bomberger, C. Tweed, W. Martin, J. Fornwald, R. Lehr, J. Harling, L. Gaster, J. F. Callahan and B. A. Olson
Molecular Pharmacology July 1, 2002, 62 (1) 58-64; DOI: https://doi.org/10.1124/mol.62.1.58

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Research ArticleArticle

Inhibition of Transforming Growth Factor (TGF)-β1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF-β Type I Receptor Kinase Activity: SB-431542

N. J. Laping, E. Grygielko, A. Mathur, S. Butter, J. Bomberger, C. Tweed, W. Martin, J. Fornwald, R. Lehr, J. Harling, L. Gaster, J. F. Callahan and B. A. Olson
Molecular Pharmacology July 1, 2002, 62 (1) 58-64; DOI: https://doi.org/10.1124/mol.62.1.58
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