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Research ArticleArticle

Selective Allosteric Enhancement of Agonist Binding and Function at Human A3 Adenosine Receptors by a Series of Imidazoquinoline Derivatives

Zhan-Guo Gao, Seong Gon Kim, Kelly A. Soltysiak, Neli Melman, Adriaan P. IJzerman and Kenneth A. Jacobson
Molecular Pharmacology July 2002, 62 (1) 81-89; DOI: https://doi.org/10.1124/mol.62.1.81
Zhan-Guo Gao
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Seong Gon Kim
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Kelly A. Soltysiak
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Neli Melman
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Adriaan P. IJzerman
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Kenneth A. Jacobson
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Article Information

vol. 62 no. 1 81-89
DOI 
https://doi.org/10.1124/mol.62.1.81
PubMed 
12065758

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 4, 2001
  • Accepted March 19, 2002
  • Published online July 1, 2002.

Copyright & Usage 
U.S. Government

Author Information

  1. Zhan-Guo Gao1,
  2. Seong Gon Kim1,
  3. Kelly A. Soltysiak1,
  4. Neli Melman1,
  5. Adriaan P. IJzerman2, and
  6. Kenneth A. Jacobson1
  1. 1Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (Z.-G.G., S.G.K., K.A.S., N.M., K.A.J.); 2Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, the Netherlands (A.P.I.)
  1. Dr. K. A. Jacobson, Molecular Recognition Section, Bldg. 8A, Rm. B1A-19, NIH, NIDDK, LBC, Bethesda, MD 20892-0810. E-mail:kajacobs{at}helix.nih.gov
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Molecular Pharmacology: 62 (1)
Molecular Pharmacology
Vol. 62, Issue 1
1 Jul 2002
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Research ArticleArticle

Selective Allosteric Enhancement of Agonist Binding and Function at Human A3 Adenosine Receptors by a Series of Imidazoquinoline Derivatives

Zhan-Guo Gao, Seong Gon Kim, Kelly A. Soltysiak, Neli Melman, Adriaan P. IJzerman and Kenneth A. Jacobson
Molecular Pharmacology July 1, 2002, 62 (1) 81-89; DOI: https://doi.org/10.1124/mol.62.1.81

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Research ArticleArticle

Selective Allosteric Enhancement of Agonist Binding and Function at Human A3 Adenosine Receptors by a Series of Imidazoquinoline Derivatives

Zhan-Guo Gao, Seong Gon Kim, Kelly A. Soltysiak, Neli Melman, Adriaan P. IJzerman and Kenneth A. Jacobson
Molecular Pharmacology July 1, 2002, 62 (1) 81-89; DOI: https://doi.org/10.1124/mol.62.1.81
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