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Molecular Pharmacology

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Table of Contents

August 01, 2002; Volume 62,Issue 2

MINIREVIEW

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    Contributions of Protein Kinase A Anchoring Proteins to Compartmentation of cAMP Signaling in the Heart
    Michael S. Kapiloff
    Molecular Pharmacology August 2002, 62 (2) 193-199; DOI: https://doi.org/10.1124/mol.62.2.193

Perspective

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    The Yin and the Yang of 5-Lipoxygenase Pathway Activation
    Timothy D. Bigby
    Molecular Pharmacology August 2002, 62 (2) 200-202; DOI: https://doi.org/10.1124/mol.62.2.200

Articles

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    Fusion Proteins with Anticoagulant and Fibrinolytic Properties: Functional Studies and Structural Considerations
    Christian Icke, Bernhard Schlott, Oliver Ohlenschläger, Manfred Hartmann, Karl-Heinz Gührs and Erika Glusa
    Molecular Pharmacology August 2002, 62 (2) 203-209; DOI: https://doi.org/10.1124/mol.62.2.203
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    The Ca2+ Channel Antagonists Mibefradil and Pimozide Inhibit Cell Growth via Different Cytotoxic Mechanisms
    Gabriel E. Bertolesi, Chanjuan Shi, Lindsy Elbaum, Christine Jollimore, Gabriela Rozenberg, Steven Barnes and Melanie E. M. Kelly
    Molecular Pharmacology August 2002, 62 (2) 210-219; DOI: https://doi.org/10.1124/mol.62.2.210
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    Re-engineering Butyrylcholinesterase as a Cocaine Hydrolase
    Hong Sun, Yuan-Ping Pang, Oksana Lockridge and Stephen Brimijoin
    Molecular Pharmacology August 2002, 62 (2) 220-224; DOI: https://doi.org/10.1124/mol.62.2.220
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    Insulin-Like Growth Factor-1–Induced Phosphorylation of Transcription Factor FKHRL1 Is Mediated by Phosphatidylinositol 3-Kinase/Akt Kinase and Role of This Pathway in Insulin-Like Growth Factor-1–Induced Survival of Cultured Hippocampal Neurons
    Wen-Hua Zheng, Satyabrata Kar and Rémi Quirion
    Molecular Pharmacology August 2002, 62 (2) 225-233; DOI: https://doi.org/10.1124/mol.62.2.225
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    The Zebrafish (Danio rerio) Aryl Hydrocarbon Receptor Type 1 Is a Novel Vertebrate Receptor
    Eric A. Andreasen, Mark E. Hahn, Warren Heideman, Richard E. Peterson and Robert L. Tanguay
    Molecular Pharmacology August 2002, 62 (2) 234-249; DOI: https://doi.org/10.1124/mol.62.2.234
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    Cyclic AMP-Mediated Inhibition of 5-Lipoxygenase Translocation and Leukotriene Biosynthesis in Human Neutrophils
    Nicolas Flamand, Marc E. Surette, Serge Picard, Sylvain Bourgoin and Pierre Borgeat
    Molecular Pharmacology August 2002, 62 (2) 250-256; DOI: https://doi.org/10.1124/mol.62.2.250
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    Apoptosis in Murine Hepatoma Hepa 1c1c7 Wild-Type, C12, and C4 Cells Mediated by Bilirubin
    John M. Seubert, Alison J. Darmon, Ayman O. S. El-Kadi, Sudhir J. A. D'Souza and John R. Bend
    Molecular Pharmacology August 2002, 62 (2) 257-264; DOI: https://doi.org/10.1124/mol.62.2.257
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    Molecular Requisites for Drug Binding to Muscle CLC-1 and Renal CLC-K Channel Revealed by the Use of Phenoxy-Alkyl Derivatives of 2-(p-Chlorophenoxy)Propionic Acid
    Antonella Liantonio, Alessio Accardi, Giuseppe Carbonara, Giuseppe Fracchiolla, Fulvio Loiodice, Paolo Tortorella, Sonia Traverso, Patrizia Guida, Sabata Pierno, Annamaria De Luca, Diana Conte Camerino and Michael Pusch
    Molecular Pharmacology August 2002, 62 (2) 265-271; DOI: https://doi.org/10.1124/mol.62.2.265
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    Ethanol Induces Gene Expression via Nuclear Compartmentalization of Receptor for Activated C Kinase 1
    Dao-Yao He, Alicia J. Vagts, Rami Yaka and Dorit Ron
    Molecular Pharmacology August 2002, 62 (2) 272-280; DOI: https://doi.org/10.1124/mol.62.2.272
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    Negative and Positive Regulatory Epitopes in the C-Terminal Domains of the Human B1 and B2 Bradykinin Receptor Subtypes Determine Receptor Coupling Efficacy to G9/11-Mediated Phospholipase Cβ Activity
    Dong Soo Kang and L. M. Fredrik Leeb-Lundberg
    Molecular Pharmacology August 2002, 62 (2) 281-288; DOI: https://doi.org/10.1124/mol.62.2.281
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    Inhibition of Branched-Chain α-Keto Acid Dehydrogenase Kinase and Sln1 Yeast Histidine Kinase by the Antifungal Antibiotic Radicicol
    Paul G. Besant, Michael V. Lasker, Cuong D. Bui and Christoph W. Turck
    Molecular Pharmacology August 2002, 62 (2) 289-296; DOI: https://doi.org/10.1124/mol.62.2.289
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    trans-Activation and Repression Properties of the Novel Nonsteroid Glucocorticoid Receptor Ligand 2,5-Dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5-(1-methylcyclohexen-3-y1)-1H-[1]benzopyrano[3,4-f]quinoline (A276575) and Its Four Stereoisomers
    Chun Wel Lin, Masaki Nakane, Mike Stashko, Doug Falls, Jane Kuk, Loan Miller, Ruth Huang, Curtis Tyree, Jeffrey N. Miner, John Rosen, Philip R. Kym, Mike J. Coghlan, George Carter and Ben C. Lane
    Molecular Pharmacology August 2002, 62 (2) 297-303; DOI: https://doi.org/10.1124/mol.62.2.297
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    Influence of Ceramide Metabolism on P-Glycoprotein Function in Immature Acute Myeloid Leukemia KG1a Cells
    Isabelle Plo, Gustav Lehne, Karen Johanne Beckstrøm, Nicolas Maestre, Ali Bettaı̈eb, Guy Laurent and Dominique Lautier
    Molecular Pharmacology August 2002, 62 (2) 304-312; DOI: https://doi.org/10.1124/mol.62.2.304
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    7,12-Dimethylbenz[a]anthracene Induces Apoptosis in Murine Pre-B Cells through a Caspase-8–Dependent Pathway
    Todd J. Page, Scott O'Brien, Colin R. Jefcoate and Charles J. Czuprynski
    Molecular Pharmacology August 2002, 62 (2) 313-319; DOI: https://doi.org/10.1124/mol.62.2.313
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    Alternative Processing of the Human FMO6 Gene Renders Transcripts Incapable of Encoding a Functional Flavin-Containing Monooxygenase
    Ronald N. Hines, Kathleen A. Hopp, Jose Franco, Kia Saeian and Frank P. Begun
    Molecular Pharmacology August 2002, 62 (2) 320-325; DOI: https://doi.org/10.1124/mol.62.2.320
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    Transcriptional Regulation of Basal Cyclooxygenase-2 Expression in Murine Lung Tumor-Derived Cell Lines by CCAAT/Enhancer-Binding Protein and Activating Transcription Factor/cAMP Response Element-Binding Protein
    Sarah A. Wardlaw, Na Zhang and Steven A. Belinsky
    Molecular Pharmacology August 2002, 62 (2) 326-333; DOI: https://doi.org/10.1124/mol.62.2.326
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    A Polymorphism in the Mouse Neuronal α4 Nicotinic Receptor Subunit Results in An Alteration in Receptor Function
    Peter Dobelis, Michael J. Marks, Paul Whiteaker, Seth A. Balogh, Allan C. Collins and Jerry A. Stitzel
    Molecular Pharmacology August 2002, 62 (2) 334-342; DOI: https://doi.org/10.1124/mol.62.2.334
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    The Intracellular Loops of the GB2 Subunit Are Crucial for G-Protein Coupling of the Heteromeric γ-Aminobutyrate B Receptor
    Michaela Havlickova, Laurent Prezeau, Beatrice Duthey, Bernhard Bettler, Jean-Philippe Pin and Jaroslav Blahos
    Molecular Pharmacology August 2002, 62 (2) 343-350; DOI: https://doi.org/10.1124/mol.62.2.343
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    Pharmacophore Model for Novel Inhibitors of Ubiquitin Isopeptidases That Induce p53-Independent Cell Death
    J. E. Mullally and F. A. Fitzpatrick
    Molecular Pharmacology August 2002, 62 (2) 351-358; DOI: https://doi.org/10.1124/mol.62.2.351
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    Transcriptional Regulation of the Human CYP3A4Gene by the Constitutive Androstane Receptor
    Bryan Goodwin, Ecushla Hodgson, Daniel J. D'Costa, Graham R. Robertson and Christopher Liddle
    Molecular Pharmacology August 2002, 62 (2) 359-365; DOI: https://doi.org/10.1124/mol.62.2.359
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    Modulation of Mouse and Human Phenobarbital-Responsive Enhancer Module by Nuclear Receptors
    Janne Mäkinen, Christian Frank, Johanna Jyrkkärinne, Jukka Gynther, Carsten Carlberg and Paavo Honkakoski
    Molecular Pharmacology August 2002, 62 (2) 366-378; DOI: https://doi.org/10.1124/mol.62.2.366
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    Oxidative Stress Decreases G Protein-Coupled Receptor Kinase 2 in Lymphocytes via a Calpain-Dependent Mechanism
    Maria Stella Lombardi, Annemieke Kavelaars, Petronila Penela, Elisabeth J. Scholtens, Marta Roccio, Reinhold E. Schmidt, Manfred Schedlowski, Federico Mayor and Cobi J. Heijnen
    Molecular Pharmacology August 2002, 62 (2) 379-388; DOI: https://doi.org/10.1124/mol.62.2.379
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    Behavioral Characterization of Mice Lacking Histamine H3 Receptors
    Hiroshi Toyota, Christine Dugovic, Muriel Koehl, Aaron D. Laposky, China Weber, Karen Ngo, Ying Wu, Doo Hyun Lee, Kazuhiko Yanai, Eiko Sakurai, Takehiko Watanabe, Changlu Liu, Jingcai Chen, Ann J. Barbier, Fred W. Turek, Wai-Ping Fung-Leung and Timothy W. Lovenberg
    Molecular Pharmacology August 2002, 62 (2) 389-397; DOI: https://doi.org/10.1124/mol.62.2.389
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    Destabilization of the HIV-1 Reverse Transcriptase Dimer upon Interaction with N-Acyl Hydrazone Inhibitors
    Nicolas Sluis-Cremer, Dominique Arion and Michael A. Parniak
    Molecular Pharmacology August 2002, 62 (2) 398-405; DOI: https://doi.org/10.1124/mol.62.2.398
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    Nicotinic Receptor M3 Transmembrane Domain: Position 8′ Contributes to Channel Gating
    María José De Rosa, Diego Rayes, Guillermo Spitzmaul and Cecilia Bouzat
    Molecular Pharmacology August 2002, 62 (2) 406-414; DOI: https://doi.org/10.1124/mol.62.2.406
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    Prenylamine Block of Nav1.5 Channel is Mediated via a Receptor Distinct from That of Local Anesthetics
    Mustafa G. Mujtaba, Sho-Ya Wang and Ging Kuo Wang
    Molecular Pharmacology August 2002, 62 (2) 415-422; DOI: https://doi.org/10.1124/mol.62.2.415
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    Inflammation Modulates the Interaction of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) I/Polypyrimidine Tract Binding Protein and hnRNP L with the 3′Untranslated Region of the Murine Inducible Nitric-Oxide Synthase mRNA
    Malin Söderberg, Françoise Raffalli-Mathieu and Matti A. Lang
    Molecular Pharmacology August 2002, 62 (2) 423-431; DOI: https://doi.org/10.1124/mol.62.2.423
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Molecular Pharmacology: 62 (2)
Molecular Pharmacology
Vol. 62, Issue 2
1 Aug 2002
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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