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Development of A Real-Time in Vivo Transcription Assay: Application Reveals Pregnane X Receptor-Mediated Induction of CYP3A4 by Cancer Chemotherapeutic Agents

Erin Schuetz, Lubin Lan, Kazuto Yasuda, Richard Kim, Thomas A. Kocarek, John Schuetz and Stephen Strom
Molecular Pharmacology September 2002, 62 (3) 439-445; DOI: https://doi.org/10.1124/mol.62.3.439

Article Information

vol. 62 no. 3 439-445
DOI 
https://doi.org/10.1124/mol.62.3.439
PubMed 
12181418
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received March 28, 2002
  • Accepted June 17, 2002
  • Published online September 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Erin Schuetz1,
  2. Lubin Lan1,
  3. Kazuto Yasuda1,
  4. Richard Kim2,
  5. Thomas A. Kocarek3,
  6. John Schuetz1, and
  7. Stephen Strom4
  1. 1Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (E.S., L.L., K.Y., J.S.); 2Department of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee (R.K.); 3Institute of Environmental Health Sciences, Wayne State University, Detroit, Michigan (T.A.K.); and 4Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania (S.S.)
  1. Erin G. Schuetz, Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 332 N. Lauderdale Avenue, Memphis, TN 38105-2794. E-mail:erin.schuetz{at}stjude.org
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Rapid CommunicationAccelerated Communication

Development of A Real-Time in Vivo Transcription Assay: Application Reveals Pregnane X Receptor-Mediated Induction of CYP3A4 by Cancer Chemotherapeutic Agents

Erin Schuetz, Lubin Lan, Kazuto Yasuda, Richard Kim, Thomas A. Kocarek, John Schuetz and Stephen Strom
Molecular Pharmacology September 1, 2002, 62 (3) 439-445; DOI: https://doi.org/10.1124/mol.62.3.439
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