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Research ArticleArticle

Restoration of Human β-Globin Gene Expression in Murine and Human IVS2–654 Thalassemic Erythroid Cells by Free Uptake of Antisense Oligonucleotides

Thipparat Suwanmanee, Halina Sierakowska, Giuseppina Lacerra, Saovaros Svasti, Suzanne Kirby, Christopher E. Walsh, Suthat Fucharoen and Ryszard Kole
Molecular Pharmacology September 2002, 62 (3) 545-553; DOI: https://doi.org/10.1124/mol.62.3.545

Article Information

vol. 62 no. 3 545-553
DOI 
https://doi.org/10.1124/mol.62.3.545
PubMed 
12181431
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received January 24, 2002
  • Accepted June 14, 2002
  • Published online September 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Thipparat Suwanmanee1,1,2,
  2. Halina Sierakowska2,1,2,
  3. Giuseppina Lacerra3,1,2,
  4. Saovaros Svasti1,2,
  5. Suzanne Kirby1,3,4,
  6. Christopher E. Walsh4,5,
  7. Suthat Fucharoen6, and
  8. Ryszard Kole1,2
  1. 1Lineberger Comprehensive Cancer Center (T.S., H.S., G.L., S.S., R.K., S.K.), Departments of 2Pharmacology (T.S., H.S., G.L., S.S., R.K.), 3Pathology (S.K.), 4Medicine (S.K., C.E.W.), and 5Gene Therapy Center (C.E.W.), University of North Carolina, Chapel Hill, North Carolina; and 6Thalassemia Research Center, Institute of Science and Technology for Research and Development, Mahidol University, Salaya Campus, Nakornpathom, Thailand (S.F.)
  1. Dr. Ryszard Kole, University of North Carolina, Lineberger Comprehensive Cancer Center, CB #7295, Chapel Hill, NC 27599-7295. E-mail: kole{at}med.unc.edu
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Research ArticleArticle

Restoration of Human β-Globin Gene Expression in Murine and Human IVS2–654 Thalassemic Erythroid Cells by Free Uptake of Antisense Oligonucleotides

Thipparat Suwanmanee, Halina Sierakowska, Giuseppina Lacerra, Saovaros Svasti, Suzanne Kirby, Christopher E. Walsh, Suthat Fucharoen and Ryszard Kole
Molecular Pharmacology September 1, 2002, 62 (3) 545-553; DOI: https://doi.org/10.1124/mol.62.3.545
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