Differential Activation of Gq/11 and Gi3 Proteins at 5-Hydroxytryptamine2C Receptors Revealed by Antibody Capture Assays: Influence of Receptor Reserve and Relationship to Agonist-Directed Trafficking

Didier Cussac, Psychopharmacology Dept., Inst. de Recherches Servier, 125 chemin de Ronde, Croissy-Sur-Seine, 78290 Paris, France. E-mail:didier.cussac{at}fr.netgrs.com

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	Abstract	Full	Pdf
Aug 2002	108	71	198
Sep 2002	32	83	127
Oct 2002	10	58	84
Nov 2002	6	33	55
Dec 2002	5	29	30
Jan 2003	5	21	20
Feb 2003	2	36	50
Mar 2003	5	27	34
Apr 2003	14	37	43
May 2003	6	18	37
Jun 2003	6	29	49
Jul 2003	21	25	23
Aug 2003	18	34	25
Sep 2003	17	36	46
Oct 2003	22	34	32
Nov 2003	26	33	43
Dec 2003	11	32	18
Jan 2004	24	36	29
Feb 2004	15	45	34
Mar 2004	30	62	34
Apr 2004	15	38	46
May 2004	17	28	17
Jun 2004	23	35	17
Jul 2004	30	27	16
Aug 2004	17	33	14
Sep 2004	15	39	20
Oct 2004	27	47	25
Nov 2004	14	34	24
Dec 2004	19	58	24
Jan 2005	27	26	13
Feb 2005	19	42	37
Mar 2005	19	46	23
Apr 2005	10	25	21
May 2005	12	33	21
Jun 2005	13	24	21
Jul 2005	10	28	19
Aug 2005	16	32	19
Sep 2005	14	35	18
Oct 2005	12	23	10
Nov 2005	14	34	12
Dec 2005	13	18	12
Jan 2006	11	24	17
Feb 2006	7	33	12
Mar 2006	6	21	9
Apr 2006	17	25	14
May 2006	7	30	38
Jun 2006	5	16	11
Jul 2006	5	16	8
Aug 2006	8	10	10
Sep 2006	7	14	11
Oct 2006	13	27	10
Nov 2006	10	30	20
Dec 2006	4	13	7
Jan 2007	12	16	10
Feb 2007	8	12	8
Mar 2007	7	20	19
Apr 2007	7	10	8
May 2007	8	24	19
Jun 2007	9	27	18
Jul 2007	5	23	21
Aug 2007	9	23	16
Sep 2007	13	21	11
Oct 2007	13	22	17
Nov 2007	9	18	22
Dec 2007	4	15	9
Jan 2008	7	20	14
Feb 2008	11	12	123
Mar 2008	9	13	16
Apr 2008	20	25	21
May 2008	6	11	8
Jun 2008	14	13	8
Jul 2008	12	15	16
Aug 2008	18	20	13
Sep 2008	98	13	9
Oct 2008	16	28	15
Nov 2008	27	8	5
Dec 2008	11	3	3
Jan 2009	9	20	13
Feb 2009	15	22	19
Mar 2009	27	17	10
Apr 2009	17	10	12
May 2009	12	16	9
Jun 2009	14	13	8
Jul 2009	14	19	15
Aug 2009	14	21	6
Sep 2009	13	10	13
Oct 2009	14	6	11
Nov 2009	19	11	10
Dec 2009	6	6	5
Jan 2010	9	11	8
Feb 2010	9	9	6
Mar 2010	10	16	13
Apr 2010	8	6	6
May 2010	13	15	9
Jun 2010	4	8	5
Jul 2010	6	11	14
Aug 2010	6	10	5
Sep 2010	7	13	8
Oct 2010	11	12	13
Nov 2010	7	12	8
Dec 2010	13	14	9
Jan 2011	5	14	16
Feb 2011	14	11	9
Mar 2011	8	7	7
Apr 2011	5	12	7
May 2011	4	14	12
Jun 2011	7	6	18
Jul 2011	10	13	13
Aug 2011	7	8	12
Sep 2011	10	13	18
Oct 2011	9	14	16
Nov 2011	13	16	12
Dec 2011	8	18	10
Jan 2012	2	9	12
Feb 2012	13	13	9
Mar 2012	26	9	11
Apr 2012	7	11	10
May 2012	12	12	17
Jun 2012	12	8	7
Jul 2012	9	17	9
Aug 2012	5	5	8
Sep 2012	12	12	17
Oct 2012	11	6	8
Nov 2012	16	7	10
Dec 2012	7	5	13
Jan 2013	9	13	4
Feb 2013	8	8	7
Mar 2013	9	9	9
Apr 2013	16	9	19
May 2013	15	5	7
Jun 2013	3	8	5
Jul 2013	13	13	12
Aug 2013	7	7	6
Sep 2013	20	13	7
Oct 2013	13	7	4
Nov 2013	10	8	6
Dec 2013	4	11	6
Jan 2014	15	5	3
Feb 2014	12	2	3
Mar 2014	4	13	3
Apr 2014	18	12	6
May 2014	5	6	4
Jun 2014	9	2	6
Jul 2014	12	14	4
Aug 2014	14	6	6
Sep 2014	10	13	8
Oct 2014	14	13	8
Nov 2014	8	14	12
Dec 2014	8	8	2
Jan 2015	6	2	3
Feb 2015	0	8	2
Mar 2015	8	9	2
Apr 2015	3	10	5
May 2015	7	17	4
Jun 2015	12	7	2
Jul 2015	57	11	10
Aug 2015	76	1	4
Sep 2015	60	1	3
Oct 2015	53	17	3
Nov 2015	44	5	3
Dec 2015	17	2	3
Jan 2016	43	7	4
Feb 2016	20	8	3
Mar 2016	13	9	17
Apr 2016	9	5	8
May 2016	30	4	2
Jun 2016	13	7	14
Jul 2016	9	8	2
Aug 2016	19	19	3
Sep 2016	12	33	2
Oct 2016	8	54	9
Nov 2016	17	65	5
Dec 2016	4	31	3
Jan 2017	1	20	4
Feb 2017	0	9	1
Mar 2017	0	27	2
Apr 2017	2	28	8
May 2017	2	22	5
Jun 2017	0	18	6
Jul 2017	2	26	4
Aug 2017	3	20	3
Sep 2017	0	17	6
Oct 2017	1	15	5
Nov 2017	0	37	4
Dec 2017	0	20	9
Jan 2018	2	17	7
Feb 2018	0	40	12
Mar 2018	1	33	7
Apr 2018	0	318	1
May 2018	0	127	5
Jun 2018	0	162	3
Jul 2018	0	126	8
Aug 2018	0	44	0
Sep 2018	0	38	8
Oct 2018	1	89	9
Nov 2018	1	87	6
Dec 2018	73	24	7
Jan 2019	59	1	1
Feb 2019	62	0	0
Mar 2019	19	5	2
Apr 2019	20	1	0
May 2019	14	8	4
Jun 2019	15	4	5
Jul 2019	8	0	0
Aug 2019	33	2	1
Sep 2019	25	2	0
Oct 2019	14	1	4
Nov 2019	19	1	0
Dec 2019	21	1	1
Jan 2020	12	3	1
Feb 2020	9	7	2
Mar 2020	13	3	1
Apr 2020	7	0	0
May 2020	4	0	0
Jun 2020	17	1	1
Jul 2020	10	1	1
Aug 2020	13	2	3
Sep 2020	6	1	0
Oct 2020	19	1	0
Nov 2020	37	0	0
Dec 2020	24	3	0
Jan 2021	31	22	4