Table of Contents

Articles

• You have access

  N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) Interaction with LYS 3.28(192) Is Crucial for Its Inverse Agonism at the Cannabinoid CB1 Receptor

  Dow P. Hurst, Diane L. Lynch, Judy Barnett-Norris, Stephen M. Hyatt, Herbert H. Seltzman, Miao Zhong, Zhao-Hui Song, Jingjiang Nie, Deborah Lewis and Patricia H. Reggio

  Molecular Pharmacology December 2002, 62 (6) 1274-1287; DOI: https://doi.org/10.1124/mol.62.6.1274
• You have access

  Characterization of Two Pharmacophores on the Multidrug Transporter P-Glycoprotein

  Alexia Garrigues, Nicolas Loiseau, Marcel Delaforge, Jacques Ferté, Manuel Garrigos, François André and Stéphane Orlowski

  Molecular Pharmacology December 2002, 62 (6) 1288-1298; DOI: https://doi.org/10.1124/mol.62.6.1288
• You have access

  Novel Roles of Liver X Receptors Exposed by Gene Expression Profiling in Liver and Adipose Tissue

  Thomas M. Stulnig, Knut R. Steffensen, Hui Gao, Mark Reimers, Karin Dahlman-Wright, Gertrud U. Schuster and Jan-Åke Gustafsson

  Molecular Pharmacology December 2002, 62 (6) 1299-1305; DOI: https://doi.org/10.1124/mol.62.6.1299
• You have access

  11β-Hydroxyprogesterone Acts as a Mineralocorticoid Agonist in Stimulating Na⁺ Absorption in Mammalian Principal Cortical Collecting Duct Cells

  Marie-Edith Rafestin-Oblin, Jerome Fagart, Anny Souque, Cendrine Seguin, Marcelle Bens and Alain Vandewalle

  Molecular Pharmacology December 2002, 62 (6) 1306-1313; DOI: https://doi.org/10.1124/mol.62.6.1306
• You have access

  Expression Profile and Up-Regulation of Prax-1 mRNA by Antidepressant Treatment in the Rat Brain

  Pascale Chardenot, Christine Roubert, Sylvaine Galiègue, Pierre Casellas, Gérard Le Fur, Philippe Soubrié and Florence Oury-Donat

  Molecular Pharmacology December 2002, 62 (6) 1314-1320; DOI: https://doi.org/10.1124/mol.62.6.1314
• You have access

  Thiopurine Metabolism and Identification of the Thiopurine Metabolites Transported by MRP4 and MRP5 Overexpressed in Human Embryonic Kidney Cells

  P. R. Wielinga, G. Reid, E. E. Challa, I. van der Heijden, L. van Deemter, M. de Haas, C. Mol, A. J. Kuil, E. Groeneveld, J. D. Schuetz, C. Brouwer, R. A. De Abreu, J. Wijnholds, J. H. Beijnen and P. Borst

  Molecular Pharmacology December 2002, 62 (6) 1321-1331; DOI: https://doi.org/10.1124/mol.62.6.1321
• You have access

  Mss4 Gene Is Up-Regulated in Rat Brain after Chronic Treatment with Antidepressant and Down-Regulated When Rats Are Anhedonic

  Christian Andriamampandry, Claude Muller, Catherine Schmidt-Mutter, Serge Gobaille, Michael Spedding, Dominique Aunis and Michel Maitre

  Molecular Pharmacology December 2002, 62 (6) 1332-1338; DOI: https://doi.org/10.1124/mol.62.6.1332
• You have access

  Phospholipase D Activation by Endogenous 5-Hydroxytryptamine 2C Receptors Is Mediated by Gα₁₃ and Pertussis Toxin-Insensitive Gβγ Subunits

  L. McGrew, M. S. S. Chang and E. Sanders-Bush

  Molecular Pharmacology December 2002, 62 (6) 1339-1343; DOI: https://doi.org/10.1124/mol.62.6.1339
• You have access

  Transcriptional Regulation of the Rat Bradykinin B2 Receptor Gene: Identification of a Silencer Element

  Heloisa A. Baptista, Maria C. W. Avellar, Ronaldo C. Araujo, Jorge L. Pesquero, Joost P. Schanstra, Jean L. Bascands, Jean P. Esteve, Antonio C. M. Paiva, Michael Bader and João B. Pesquero

  Molecular Pharmacology December 2002, 62 (6) 1344-1355; DOI: https://doi.org/10.1124/mol.62.6.1344
• You have access

  Inhibition of Protein Tyrosine/Mitogen-Activated Protein Kinase Phosphatase Activity Is Associated with D₂ Dopamine Receptor Supersensitivity in a Rat Model of Parkinson's Disease

  Xuechu Zhen, Claudio Torres, Guoping Cai and Eitan Friedman

  Molecular Pharmacology December 2002, 62 (6) 1356-1363; DOI: https://doi.org/10.1124/mol.62.6.1356
• You have access

  Discovery of Novel Targets of Quinoline Drugs in the Human Purine Binding Proteome

  Paul R. Graves, Jesse J. Kwiek, Patrick Fadden, Rupa Ray, Klaas Hardeman, Andrew M. Coley, Michael Foley and Timothy A. J. Haystead

  Molecular Pharmacology December 2002, 62 (6) 1364-1372; DOI: https://doi.org/10.1124/mol.62.6.1364
• You have access

  A₃ Adenosine Receptors in Human Astrocytoma Cells: Agonist-Mediated Desensitization, Internalization, and Down-Regulation

  M. L. Trincavelli, D. Tuscano, M. Marroni, A. Falleni, V. Gremigni, S. Ceruti, M. P. Abbracchio, K. A. Jacobson, F. Cattabeni and C. Martini

  Molecular Pharmacology December 2002, 62 (6) 1373-1384; DOI: https://doi.org/10.1124/mol.62.6.1373
• You have access

  Mechanism of Extracellular Signal-Regulated Kinase Activation by the CB₁ Cannabinoid Receptor

  Ismael Galve-Roperh, Daniel Rueda, Teresa Gómez del Pulgar, Guillermo Velasco and Manuel Guzmán

  Molecular Pharmacology December 2002, 62 (6) 1385-1392; DOI: https://doi.org/10.1124/mol.62.6.1385
• You have access

  Alteration of Intrinsic Biological Rhythms during Interferon Treatment and Its Possible Mechanism

  Satoru Koyanagi and Shigehiro Ohdo

  Molecular Pharmacology December 2002, 62 (6) 1393-1399; DOI: https://doi.org/10.1124/mol.62.6.1393
• You have access

  c-Myc Exerts a Protective Function through Ornithine Decarboxylase against Cellular Insults

  Jong Kuk Park, Young Min Chung, Seongman Kang, Jae-Uk Kim, Yun-Taik Kim, Hyung Jung Kim, Yeul Hong Kim, Jun Suk Kim and Young Do Yoo

  Molecular Pharmacology December 2002, 62 (6) 1400-1408; DOI: https://doi.org/10.1124/mol.62.6.1400
• You have access

  Enhancement of Metabolic Oxidative Stress-Induced Cytotoxicity by the Thioredoxin Inhibitor 1-Methylpropyl 2-Imidazolyl Disulfide Is Mediated through the ASK1-SEK1-JNK1 Pathway

  Yong J. Lee, Jin H. Kim, Jun Chen and Jae J. Song

  Molecular Pharmacology December 2002, 62 (6) 1409-1417; DOI: https://doi.org/10.1124/mol.62.6.1409
• You have access

  Characteristics of Block by Pb²⁺ of Function of Human Neuronal L-, N-, and R-Type Ca²⁺ Channels Transiently Expressed in Human Embryonic Kidney 293 Cells

  Shuangqing Peng, Ravindra K. Hajela and William D. Atchison

  Molecular Pharmacology December 2002, 62 (6) 1418-1430; DOI: https://doi.org/10.1124/mol.62.6.1418
• You have access

  Mutation of Asn293 to Asp in Transmembrane Helix VI Abolishes Agonist-Induced but Not Constitutive Activity of the β₂-Adrenergic Receptor

  Annette Hannawacker, Cornelius Krasel and Martin J. Lohse

  Molecular Pharmacology December 2002, 62 (6) 1431-1437; DOI: https://doi.org/10.1124/mol.62.6.1431
• You have access

  P2X₁ Receptor-Deficient Mice Establish the Native P2X Receptor and a P2Y₆-Like Receptor in Arteries

  Catherine Vial and Richard J. Evans

  Molecular Pharmacology December 2002, 62 (6) 1438-1445; DOI: https://doi.org/10.1124/mol.62.6.1438
• You have access

  Overexpression of Protein Kinase Cζ Confers Protection Against Antileukemic Drugs by Inhibiting the Redox-Dependent Sphingomyelinase Activation

  Christine Bezombes, Aurélie de Thonel, Andriana Apostolou, Thierry Louat, Jean-Pierre Jaffrézou, Guy Laurent and Anne Quillet-Mary

  Molecular Pharmacology December 2002, 62 (6) 1446-1455; DOI: https://doi.org/10.1124/mol.62.6.1446
• You have access

  Assembly with the Kvβ1.3 Subunit Modulates Drug Block of hKv1.5 Channels

  Teresa González, Ricardo Navarro-Polanco, Cristina Arias, Ricardo Caballero, Ignacio Moreno, Eva Delpón, Juan Tamargo, Michael M. Tamkun and Carmen Valenzuela

  Molecular Pharmacology December 2002, 62 (6) 1456-1463; DOI: https://doi.org/10.1124/mol.62.6.1456
• You have access

  Opioid Agonists Differentially Regulate μ-Opioid Receptors and Trafficking Proteins in Vivo

  Minesh B. Patel, Chintan N. Patel, Vikram Rajashekara and Byron C. Yoburn

  Molecular Pharmacology December 2002, 62 (6) 1464-1470; DOI: https://doi.org/10.1124/mol.62.6.1464
• You have access

  Commitment of Activated T Cells to Secondary Responsiveness Is Enhanced by Signals Mediated by cAMP-Dependent Protein Kinase A-I

  Monika Vig, Anna George, Ranjan Sen, Jeannine Durdik, Satyajit Rath and Vineeta Bal

  Molecular Pharmacology December 2002, 62 (6) 1471-1481; DOI: https://doi.org/10.1124/mol.62.6.1471
• You have access

  Identification of PKCα Isoform-Specific Effects in Cardiac Myocytes Using Antisense Phosphorothioate Oligonucleotides

  Risto Kerkelä, Mika Ilves, Sampsa Pikkarainen, Heikki Tokola, Jarkko Ronkainen, Olli Vuolteenaho, Juhani Leppäluoto and Heikki Ruskoaho

  Molecular Pharmacology December 2002, 62 (6) 1482-1491; DOI: https://doi.org/10.1124/mol.62.6.1482
• You have access

  Analogs of WIN 62,577 Define a Second Allosteric Site on Muscarinic Receptors

  S. Lazareno, A. Popham and N. J. M. Birdsall

  Molecular Pharmacology December 2002, 62 (6) 1492-1505; DOI: https://doi.org/10.1124/mol.62.6.1492
• You have access

  Reduction of G Protein-Coupled Receptor Kinase 2 Expression in U-937 Cells Attenuates H2 Histamine Receptor Desensitization and Induces Cell Maturation

  Natalia Fernández, Federico Monczor, Bibiana Lemos, Cintia Notcovich, Alberto Baldi, Carlos Davio and Carina Shayo

  Molecular Pharmacology December 2002, 62 (6) 1506-1514; DOI: https://doi.org/10.1124/mol.62.6.1506
• You have access

  Mechanisms Underlying Nonsteroidal Anti-Inflammatory Drug-Induced p27 ^Kip1 Expression

  Yu-Chun Huang, Lea-Yea Chuang and Wen-Chun Hung

  Molecular Pharmacology December 2002, 62 (6) 1515-1521; DOI: https://doi.org/10.1124/mol.62.6.1515