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Research ArticleArticle

Growth Inhibition by the Farnesyltransferase Inhibitor FTI-277 Involves Bcl-2 Expression and Defective Association with Raf-1 in Liver Cancer Cell Lines

Antonio Mazzocca, Sabrina Giusti, Andrew D. Hamilton, Said M. Sebti, Pietro Pantaleo and Vinicio Carloni
Molecular Pharmacology January 2003, 63 (1) 159-166; DOI: https://doi.org/10.1124/mol.63.1.159

Article Information

vol. 63 no. 1 159-166
DOI 
https://doi.org/10.1124/mol.63.1.159
PubMed 
12488548
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received May 1, 2002
  • Accepted September 3, 2002
  • Published online January 1, 2003.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Antonio Mazzocca1,
  2. Sabrina Giusti2,
  3. Andrew D. Hamilton3,
  4. Said M. Sebti4,
  5. Pietro Pantaleo1, and
  6. Vinicio Carloni1
  1. 1Dipartimento di Medicina Interna, Università di Firenze, Firenze, Italy (A.M., P.P., V.C.); 2U.O. Oncologia Medica, Ospedale San Donato, Arezzo, Italy (S.G.); 3Department of Chemistry, Yale University, New Haven, Connecticut (A.D.H.); and 4Drug Discovery Program, H. Lee Moffitt Cancer Center and the Department of Biochemistry and Molecular Biology, University of South Florida, Tampa, Florida (S.M.S.)
  1. Vinicio Carloni, M.D., Ph. D., Dipartimento di Medicina Interna, Università di Firenze, Viale Morgagni,85, I-50134 Firenze, Italy. E-mail:v.carloni{at}dfc.unifi.it
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Research ArticleArticle

Growth Inhibition by the Farnesyltransferase Inhibitor FTI-277 Involves Bcl-2 Expression and Defective Association with Raf-1 in Liver Cancer Cell Lines

Antonio Mazzocca, Sabrina Giusti, Andrew D. Hamilton, Said M. Sebti, Pietro Pantaleo and Vinicio Carloni
Molecular Pharmacology January 1, 2003, 63 (1) 159-166; DOI: https://doi.org/10.1124/mol.63.1.159
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