Detection of Thymidylate Synthase Modulators by a Novel Screening Assay

Dr. Bruce J. Dolnick, Grace Cancer Drug Center, Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263. E-mail: bruce.dolnick{at}roswellpark.org.

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	Abstract	Full	Pdf
Dec 2002	16	28	31
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Mar 2003	7	34	22
Apr 2003	4	22	24
May 2003	5	60	15
Jun 2003	2	17	12
Jul 2003	9	25	17
Aug 2003	6	16	8
Sep 2003	8	14	14
Oct 2003	11	14	8
Nov 2003	14	17	15
Dec 2003	8	15	14
Jan 2004	12	22	8
Feb 2004	8	27	31
Mar 2004	16	28	15
Apr 2004	9	29	12
May 2004	9	27	11
Jun 2004	14	30	19
Jul 2004	14	32	6
Aug 2004	14	20	7
Sep 2004	6	24	3
Oct 2004	13	31	19
Nov 2004	8	35	8
Dec 2004	6	33	13
Jan 2005	14	34	8
Feb 2005	14	23	13
Mar 2005	13	28	16
Apr 2005	2	13	14
May 2005	6	30	6
Jun 2005	9	17	7
Jul 2005	6	22	7
Aug 2005	7	11	5
Sep 2005	8	12	7
Oct 2005	6	9	7
Nov 2005	4	24	13
Dec 2005	6	21	8
Jan 2006	4	18	8
Feb 2006	5	21	8
Mar 2006	5	29	17
Apr 2006	0	5	4
May 2006	2	17	7
Jun 2006	2	11	5
Jul 2006	3	15	8
Aug 2006	2	6	3
Sep 2006	3	10	5
Oct 2006	4	14	8
Nov 2006	10	8	4
Dec 2006	4	10	14
Jan 2007	2	11	6
Feb 2007	2	8	3
Mar 2007	1	16	9
Apr 2007	4	19	6
May 2007	2	6	9
Jun 2007	6	5	9
Jul 2007	5	11	9
Aug 2007	4	11	8
Sep 2007	3	10	18
Oct 2007	2	20	12
Nov 2007	0	7	4
Dec 2007	2	11	4
Jan 2008	2	12	3
Feb 2008	10	15	9
Mar 2008	4	16	9
Apr 2008	6	21	11
May 2008	2	26	13
Jun 2008	4	32	4
Jul 2008	7	18	11
Aug 2008	10	26	9
Sep 2008	21	31	4
Oct 2008	7	5	4
Nov 2008	8	11	9
Dec 2008	3	15	4
Jan 2009	4	10	4
Feb 2009	5	15	6
Mar 2009	9	21	11
Apr 2009	2	6	9
May 2009	1	6	4
Jun 2009	2	3	3
Jul 2009	6	11	4
Aug 2009	4	7	1
Sep 2009	6	11	6
Oct 2009	5	9	6
Nov 2009	2	9	9
Dec 2009	4	6	11
Jan 2010	3	6	4
Feb 2010	5	5	6
Mar 2010	3	12	11
Apr 2010	2	3	5
May 2010	2	2	3
Jun 2010	6	10	7
Jul 2010	0	11	14
Aug 2010	4	3	7
Sep 2010	2	5	7
Oct 2010	4	13	10
Nov 2010	6	4	8
Dec 2010	3	16	4
Jan 2011	10	7	7
Feb 2011	2	1	3
Mar 2011	5	8	12
Apr 2011	3	5	6
May 2011	2	6	9
Jun 2011	15	9	3
Jul 2011	13	30	10
Aug 2011	6	5	8
Sep 2011	4	4	1
Oct 2011	3	8	3
Nov 2011	4	10	8
Dec 2011	2	2	7
Jan 2012	3	1	7
Feb 2012	9	5	7
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Apr 2012	6	5	6
May 2012	4	4	10
Jun 2012	4	2	0
Jul 2012	7	6	9
Aug 2012	2	2	5
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Oct 2012	5	6	13
Nov 2012	2	3	9
Dec 2012	5	3	10
Jan 2013	4	6	15
Feb 2013	5	3	4
Mar 2013	3	4	0
Apr 2013	3	6	13
May 2013	4	1	4
Jun 2013	1	2	3
Jul 2013	8	2	8
Aug 2013	3	0	5
Sep 2013	7	1	5
Oct 2013	8	7	23
Nov 2013	3	1	9
Dec 2013	6	1	3
Jan 2014	6	1	6
Feb 2014	2	2	6
Mar 2014	2	1	6
Apr 2014	7	1	12
May 2014	4	0	9
Jun 2014	1	2	12
Jul 2014	4	1	4
Aug 2014	4	6	5
Sep 2014	2	4	10
Oct 2014	6	7	6
Nov 2014	0	8	5
Dec 2014	4	3	4
Jan 2015	1	4	4
Feb 2015	0	0	1
Mar 2015	1	2	2
Apr 2015	3	3	9
May 2015	6	4	3
Jun 2015	9	5	6
Jul 2015	9	9	4
Aug 2015	9	8	2
Sep 2015	6	8	4
Oct 2015	2	2	2
Nov 2015	1	3	7
Dec 2015	1	3	12
Jan 2016	7	0	8
Feb 2016	3	6	7
Mar 2016	22	2	14
Apr 2016	24	2	7
May 2016	25	3	6
Jun 2016	26	3	3
Jul 2016	32	6	5
Aug 2016	25	2	4
Sep 2016	22	3	3
Oct 2016	22	13	5
Nov 2016	24	8	4
Dec 2016	10	7	3
Jan 2017	0	5	0
Feb 2017	0	6	6
Mar 2017	0	16	2
Apr 2017	0	8	3
May 2017	0	5	6
Jun 2017	0	9	2
Jul 2017	0	12	1
Aug 2017	1	10	3
Sep 2017	1	15	1
Oct 2017	0	10	1
Nov 2017	0	14	1
Dec 2017	0	17	4
Jan 2018	0	8	5
Feb 2018	0	9	3
Mar 2018	0	11	1
Apr 2018	0	18	3
May 2018	0	16	8
Jun 2018	0	28	5
Jul 2018	0	7	2
Aug 2018	0	3	0
Sep 2018	0	27	4
Oct 2018	0	15	0
Nov 2018	0	9	1
Dec 2018	9	3	1
Jan 2019	5	1	0
Feb 2019	10	0	0
Mar 2019	7	0	0
Apr 2019	10	1	0
May 2019	6	0	0
Jun 2019	13	0	2
Jul 2019	7	2	0
Aug 2019	15	0	0
Sep 2019	13	1	1
Oct 2019	7	3	2
Nov 2019	18	0	0
Dec 2019	6	0	0
Jan 2020	17	1	0
Feb 2020	8	0	0
Mar 2020	8	1	0
Apr 2020	10	0	0
May 2020	3	0	0
Jun 2020	8	3	0
Jul 2020	7	0	0
Aug 2020	10	2	1
Sep 2020	3	0	0
Oct 2020	11	0	0
Nov 2020	3	0	0
Dec 2020	2	2	0
Jan 2021	13	6	1