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Molecular Pharmacology

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Table of Contents

March 01, 2003; Volume 63,Issue 3

MINIREVIEW

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    Calmodulin-Regulated Adenylyl Cyclases: Cross-Talk and Plasticity in the Central Nervous System
    Hongbing Wang and Daniel R. Storm
    Molecular Pharmacology March 2003, 63 (3) 463-468; DOI: https://doi.org/10.1124/mol.63.3.463

Perspective

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    A New Endothelial Target for Cannabinoids
    Michael D. Randall
    Molecular Pharmacology March 2003, 63 (3) 469-470; DOI: https://doi.org/10.1124/mol.63.3.469

Accelerated Communication

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    Expression and Characterization of a 5-oxo-6E,8Z,11Z,14Z-Eicosatetraenoic Acid Receptor Highly Expressed on Human Eosinophils and Neutrophils
    Carol E. Jones, Suzanne Holden, Laurent Tenaillon, Umesh Bhatia, Klaus Seuwen, Pamela Tranter, Jonathan Turner, Rachel Kettle, Rochdi Bouhelal, Steven Charlton, N. R. Nirmala, Gabor Jarai and Peter Finan
    Molecular Pharmacology March 2003, 63 (3) 471-477; DOI: https://doi.org/10.1124/mol.63.3.471

Articles

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    Differential Requirement of Gα12, Gα13, Gαq, and Gβγ for Endothelin-1-Induced c-Jun NH2-Terminal Kinase and Extracellular Signal-Regulated Kinase Activation
    Ken Arai, Yoshiko Maruyama, Motohiro Nishida, Shihori Tanabe, Shuichi Takagahara, Tohru Kozasa, Yasuo Mori, Taku Nagao and Hitoshi Kurose
    Molecular Pharmacology March 2003, 63 (3) 478-488; DOI: https://doi.org/10.1124/mol.63.3.478
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    Influence of Molecular Structure on Substrate Binding to the Human Organic Cation Transporter, hOCT1
    Dallas Bednarczyk, Sean Ekins, James H. Wikel and Stephen H. Wright
    Molecular Pharmacology March 2003, 63 (3) 489-498; DOI: https://doi.org/10.1124/mol.63.3.489
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    Molecular Modeling of Interactions of Dihydropyridines and Phenylalkylamines with the Inner Pore of the L-Type Ca2+Channel
    Gregory M. Lipkind and Harry A. Fozzard
    Molecular Pharmacology March 2003, 63 (3) 499-511; DOI: https://doi.org/10.1124/mol.63.3.499
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    Potentiation of Lipopolysaccharide-Inducible Cyclooxygenase 2 Expression by C2-Ceramide via c-Jun N-Terminal Kinase-Mediated Activation of CCAAT/Enhancer Binding Protein β in Macrophages
    Yang Hee Cho, Chang Ho Lee and Sang Geon Kim
    Molecular Pharmacology March 2003, 63 (3) 512-523; DOI: https://doi.org/10.1124/mol.63.3.512
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    Molecular Mechanism of Nuclear Translocation of an Orphan Nuclear Receptor, SXR
    Katsuyoshi Kawana, Togo Ikuta, Yasuhito Kobayashi, Osamu Gotoh, Ken Takeda and Kaname Kawajiri
    Molecular Pharmacology March 2003, 63 (3) 524-531; DOI: https://doi.org/10.1124/mol.63.3.524
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    In Vitro Study of the Functional Expression of Organic Anion Transporting Polypeptide 3 at Rat Choroid Plexus Epithelial Cells and Its Involvement in the Cerebrospinal Fluid-to-Blood Transport of Estrone-3-Sulfate
    Sumio Ohtsuki, Takuya Takizawa, Hitomi Takanaga, Nobuyuki Terasaki, Takeo Kitazawa, Masako Sasaki, Takaaki Abe, Ken-ichi Hosoya and Tetsuya Terasaki
    Molecular Pharmacology March 2003, 63 (3) 532-537; DOI: https://doi.org/10.1124/mol.63.3.532
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    Structural Analysis of the Activation of Ribavirin Analogs by NDP Kinase: Comparison with Other Ribavirin Targets
    Sarah Gallois-Montbrun, Yuxing Chen, Hélène Dutartre, Magali Sophys, Solange Morera, Catherine Guerreiro, Benoit Schneider, Laurence Mulard, Joël Janin, Michel Veron, Dominique Deville-Bonne and Bruno Canard
    Molecular Pharmacology March 2003, 63 (3) 538-546; DOI: https://doi.org/10.1124/mol.63.3.538
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    Molecular Site of Action of the Antiarrhythmic Drug Propafenone at the Voltage-Operated Potassium Channel Kv2.1
    Michael Madeja, Thorsten Leicher, Patrick Friederich, Mark A. Punke, Wilhelm Haverkamp, Ulrich Mußhoff, Günter Breithardt and Erwin-Josef Speckmann
    Molecular Pharmacology March 2003, 63 (3) 547-556; DOI: https://doi.org/10.1124/mol.63.3.547
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    Differential Regulation of Nonsteroidal Anti-Inflammatory Drug-Activated Gene in Normal Human Tracheobronchial Epithelial and Lung Carcinoma Cells by Retinoids
    Donna Newman, Morito Sakaue, Ja Seok Koo, Kyung-Su Kim, Seung Joon Baek, Thomas Eling and Anton M. Jetten
    Molecular Pharmacology March 2003, 63 (3) 557-564; DOI: https://doi.org/10.1124/mol.63.3.557
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    N-(4-Hydroxyphenyl)retinamide Inhibits Retinoblastoma Growth through Reactive Oxygen Species-Mediated Cell Death
    Francesca Tosetti, Roberta Venè, Giuseppe Arena, Monica Morini, Simona Minghelli, Douglas M. Noonan and Adriana Albini
    Molecular Pharmacology March 2003, 63 (3) 565-573; DOI: https://doi.org/10.1124/mol.63.3.565
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    Deficiency of Nicotinic Acetylcholine Receptor β4 Subunit Causes Autonomic Cardiac and Intestinal Dysfunction
    Ningshan Wang, Avi Orr-Urtreger, Joab Chapman, Ruth Rabinowitz and Amos D. Korczyn
    Molecular Pharmacology March 2003, 63 (3) 574-580; DOI: https://doi.org/10.1124/mol.63.3.574
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    Differential Effects of Catalase on Apoptosis Induction in Human Promonocytic Cells. Relationships with Heat-Shock Protein Expression
    Patricia Sancho, Alfonso Troyano, Carlos Fernández, Elena De Blas and Patricio Aller
    Molecular Pharmacology March 2003, 63 (3) 581-589; DOI: https://doi.org/10.1124/mol.63.3.581
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    Human Renal Organic Anion Transporter 1-Dependent Uptake and Toxicity of Mercuric-Thiol Conjugates in Madin-Darby Canine Kidney Cells
    Amy G. Aslamkhan, Yong-Hae Han, Xiao-Ping Yang, Rudolfs K. Zalups and John B. Pritchard
    Molecular Pharmacology March 2003, 63 (3) 590-596; DOI: https://doi.org/10.1124/mol.63.3.590
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    Functional Analysis of Murine Aryl Hydrocarbon (AH) Receptors Defective in Nuclear Import: Impact on AH Receptor Degradation and Gene Regulation
    Zhijuan Song and Richard S. Pollenz
    Molecular Pharmacology March 2003, 63 (3) 597-606; DOI: https://doi.org/10.1124/mol.63.3.597
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    Activation of p38 Mitogen-Activated Protein Kinase and Activator Protein-1 during the Promotion of Neurite Extension of PC-12 Cells by 15-Deoxy-Δ12,14-prostaglandin J2
    Kyung Mi Jung, Ki Sook Park, Jae Ho Oh, Soo Youn Jung, Ki Hwa Yang, Youn Sook Song, Dong Ju Son, Young Hyun Park, Yeo Pyo Yun, Myung Koo Lee, Ki Wan Oh and Jin Tae Hong
    Molecular Pharmacology March 2003, 63 (3) 607-616; DOI: https://doi.org/10.1124/mol.63.3.607
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    Erythromycin, Roxithromycin, and Clarithromycin: Use of Slow-Binding Kinetics to Compare Their in Vitro Interaction with a Bacterial Ribosomal Complex Active in Peptide Bond Formation
    George P. Dinos, Sean R. Connell, Knud H. Nierhaus and Dimitrios L. Kalpaxis
    Molecular Pharmacology March 2003, 63 (3) 617-623; DOI: https://doi.org/10.1124/mol.63.3.617
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    Small Ligands Modulating the Activity of Mammalian Adenylyl Cyclases: A Novel Mode of Inhibition by Calmidazolium
    Anders Haunsø, James Simpson and Ferenc A. Antoni
    Molecular Pharmacology March 2003, 63 (3) 624-631; DOI: https://doi.org/10.1124/mol.63.3.624
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    Telomere Dysfunction Increases Cisplatin and Ecteinascidin-743 Sensitivity of Melanoma Cells
    Annamaria Biroccio, Chiara Gabellini, Sarah Amodei, Barbara Benassi, Donatella Del Bufalo, Raffaella Elli, Anna Antonelli, Maurizio D'Incalci and Gabriella Zupi
    Molecular Pharmacology March 2003, 63 (3) 632-638; DOI: https://doi.org/10.1124/mol.63.3.632
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    Purinergic P2Y12 Receptor Blockade Inhibits Shear-Induced Platelet Phosphatidylinositol 3-Kinase Activation
    Julio C. Reséndiz, Shuju Feng, Guilan Ji, Ketia A. Francis, Michael C. Berndt and Michael H. Kroll
    Molecular Pharmacology March 2003, 63 (3) 639-645; DOI: https://doi.org/10.1124/mol.63.3.639
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    Ruthenium Red Inhibits TASK-3 Potassium Channel by Interconnecting Glutamate 70 of the Two Subunits
    Gábor Czirják and Péter Enyedi
    Molecular Pharmacology March 2003, 63 (3) 646-652; DOI: https://doi.org/10.1124/mol.63.3.646
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    Cocaine Affinity Decreased by Mutations of Aromatic Residue Phenylalanine 105 in the Transmembrane Domain 2 of Dopamine Transporter
    Xiaohong Wu and Howard H. Gu
    Molecular Pharmacology March 2003, 63 (3) 653-658; DOI: https://doi.org/10.1124/mol.63.3.653
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    Different Ability of Clenbuterol and Salbutamol to Block Sodium Channels Predicts Their Therapeutic Use in Muscle Excitability Disorders
    Jean-François Desaphy, Sabata Pierno, Annamaria De Luca, Paola Didonna and Diana Conte Camerino
    Molecular Pharmacology March 2003, 63 (3) 659-670; DOI: https://doi.org/10.1124/mol.63.3.659
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    Selective Inhibitors of Cyclooxygenase-2 Delay the Activation of Nuclear Factor κB and Attenuate the Expression of Inflammatory Genes in Murine Macrophages Treated with Lipopolysaccharide
    Nuria A. Callejas, Amalia Fernández-Martı́nez, Antonio Castrillo, Lisardo Boscá and Paloma Martı́n-Sanz
    Molecular Pharmacology March 2003, 63 (3) 671-677; DOI: https://doi.org/10.1124/mol.63.3.671
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    Increased Antiviral Activity of 1-O-Hexadecyloxypropyl-[2-14C]cidofovir in MRC-5 Human Lung Fibroblasts Is Explained by Unique Cellular Uptake and Metabolism
    Kathy A. Aldern, Stephanie L. Ciesla, Kristine L. Winegarden and Karl Y. Hostetler
    Molecular Pharmacology March 2003, 63 (3) 678-681; DOI: https://doi.org/10.1124/mol.63.3.678
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    Pharmacological Interference with Dimerization of Human Neuronal Nitric-Oxide Synthase Expressed in Adenovirus-Infected DLD-1 Cells
    Hans-Jörg Habisch, Antonius C. F. Gorren, Haiying Liang, Richard C. Venema, John F. Parkinson, Kurt Schmidt and Bernd Mayer
    Molecular Pharmacology March 2003, 63 (3) 682-689; DOI: https://doi.org/10.1124/mol.63.3.682
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    Cyclic AMP Inhibition of Tumor Necrosis Factor α Production Induced by Amyloidogenic C-Terminal Peptide of Alzheimer's Amyloid Precursor Protein in Macrophages: Involvement of Multiple Intracellular Pathways and Cyclic AMP Response Element Binding Protein
    Young Hae Chong, Yoo Jung Shin and Yoo-Hun Suh
    Molecular Pharmacology March 2003, 63 (3) 690-698; DOI: https://doi.org/10.1124/mol.63.3.690
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    Selective Ligands and Cellular Effectors of a G Protein-Coupled Endothelial Cannabinoid Receptor
    László Offertáler, Fong-Ming Mo, Sándor Bátkai, Jie Liu, Malcolm Begg, Raj K. Razdan, Billy R. Martin, Richard D. Bukoski and George Kunos
    Molecular Pharmacology March 2003, 63 (3) 699-705; DOI: https://doi.org/10.1124/mol.63.3.699
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    Poly(ADP-ribose) Polymerase Activation and Changes in Bax Protein Expression Associated with Extracellular ATP-Mediated Apoptosis in Human Embryonic Kidney 293-P2X7 Cells
    Long T. Wen, Charles C. Caldwell and Aileen F. Knowles
    Molecular Pharmacology March 2003, 63 (3) 706-713; DOI: https://doi.org/10.1124/mol.63.3.706
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    Tumor Necrosis Factor-α–Induced Activation of RhoA in Airway Smooth Muscle Cells: Role in the Ca2+ Sensitization of Myosin Light Chain20 Phosphorylation
    Irene Hunter, Hannah J. Cobban, Peter Vandenabeele, David J. MacEwan and Graeme F. Nixon
    Molecular Pharmacology March 2003, 63 (3) 714-721; DOI: https://doi.org/10.1124/mol.63.3.714
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    Dehydroepiandrosterone Affects the Expression of Multiple Genes in Rat Liver Including 11β-Hydroxysteroid Dehydrogenase Type 1: A cDNA Array Analysis
    Shi Gu, Sharon L. Ripp, Russell A. Prough and Thomas E. Geoghegan
    Molecular Pharmacology March 2003, 63 (3) 722-731; DOI: https://doi.org/10.1124/mol.63.3.722
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    Hypersensitivity Reactions to Carbamazepine: Characterization of the Specificity, Phenotype, and Cytokine Profile of Drug-Specific T Cell Clones
    D. J. Naisbitt, M. Britschgi, G. Wong, J. Farrell, J. P. H. Depta, D. W. Chadwick, W. J. Pichler, M. Pirmohamed and B. K. Park
    Molecular Pharmacology March 2003, 63 (3) 732-741; DOI: https://doi.org/10.1124/mol.63.3.732
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    Usefulness of Liposomes Loaded with Cytostatic Bile Acid Derivatives to Circumvent Chemotherapy Resistance of Enterohepatic Tumors
    Oscar Briz, Rocio I. R. Macias, Marta Vallejo, Augusto Silva, Maria Angeles Serrano and Jose J. G. Marin
    Molecular Pharmacology March 2003, 63 (3) 742-750; DOI: https://doi.org/10.1124/mol.63.3.742
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    Mechanism of Corticotropin-Releasing Factor Type I Receptor Regulation by Nonpeptide Antagonists
    Sam R. J. Hoare, Sue K. Sullivan, Nicholas Ling, Paul D. Crowe and Dimitri E. Grigoriadis
    Molecular Pharmacology March 2003, 63 (3) 751-765; DOI: https://doi.org/10.1124/mol.63.3.751
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    Genotoxic Profiling of MCF-7 Breast Cancer Cell Line Elucidates Gene Expression Modifications Underlying Toxicity of the Anticancer Drug 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole
    Anne Monks, Erik Harris, Curtis Hose, John Connelly and Edward A. Sausville
    Molecular Pharmacology March 2003, 63 (3) 766-772; DOI: https://doi.org/10.1124/mol.63.3.766
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Molecular Pharmacology: 63 (3)
Molecular Pharmacology
Vol. 63, Issue 3
1 Mar 2003
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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