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Research ArticleArticle

A Key Role for Caspase-2 and Caspase-3 in the Apoptosis Induced by 2-Chloro-2′-deoxy-adenosine (Cladribine) and 2-Chloro-adenosine in Human Astrocytoma Cells

Stefania Ceruti, Elena Beltrami, Paola Matarrese, Alessia Mazzola, Flaminio Cattabeni, Walter Malorni and Maria P. Abbracchio
Molecular Pharmacology June 2003, 63 (6) 1437-1447; DOI: https://doi.org/10.1124/mol.63.6.1437

Article Information

vol. 63 no. 6 1437-1447
DOI 
https://doi.org/10.1124/mol.63.6.1437
PubMed 
12761355
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received November 25, 2002
  • Accepted March 14, 2003
  • Published online June 1, 2003.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Stefania Ceruti,
  2. Elena Beltrami,
  3. Paola Matarrese,
  4. Alessia Mazzola,
  5. Flaminio Cattabeni,
  6. Walter Malorni, and
  7. Maria P. Abbracchio
  1. Department of Pharmacological Sciences, School of Pharmacy (S.C., E.B., A.M., F.C., M.P.A.) and Center of Excellence for Neurodegenerative Diseases (S.C., F.C., M.P.A.), University of Milan, Milan, Italy; and Department of Ultrastructures, Istituto Superiore di Sanitá, Rome, Italy (P.M., W.M.)
  1. Address correspondence to:
    Prof. Maria P. Abbracchio-Department of Pharmacological Sciences, University of Milan and Center of Excellence for Neurodegenerative Diseases (CEND)-Via Balzaretti, 9-20133 Milan, Italy. E-mail: mariapia.abbracchio{at}unimi.it
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Research ArticleArticle

A Key Role for Caspase-2 and Caspase-3 in the Apoptosis Induced by 2-Chloro-2′-deoxy-adenosine (Cladribine) and 2-Chloro-adenosine in Human Astrocytoma Cells

Stefania Ceruti, Elena Beltrami, Paola Matarrese, Alessia Mazzola, Flaminio Cattabeni, Walter Malorni and Maria P. Abbracchio
Molecular Pharmacology June 1, 2003, 63 (6) 1437-1447; DOI: https://doi.org/10.1124/mol.63.6.1437
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