Molecular Pharmacology: 64 (1)

July 01, 2003; Volume 64,Issue 1

Perspective

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New Insights into G-Protein-Coupled Receptor Signaling from the Melanocortin Receptor System
Brinda K. Rana

Molecular Pharmacology July 2003, 64 (1) 1-4; DOI: https://doi.org/10.1124/mol.64.1.1

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Identification of a Site in GluR1 and GluR2 That Is Important for Modulation of Deactivation and Desensitization
J. Duncan Leever, Suzanne Clark, Autumn M. Weeks and Kathryn M. Partin

Molecular Pharmacology July 2003, 64 (1) 5-10; DOI: https://doi.org/10.1124/mol.64.1.5

Articles

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Spatial Regulation of Gαi Protein Signaling in Clathrin-Coated Membrane Microdomains Containing GAIP
Eric Elenko, Thierry Fischer, Ingrid Niesman, Tim Harding, Tammie McQuistan, Mark Von Zastrow and Marilyn G. Farquhar

Molecular Pharmacology July 2003, 64 (1) 11-20; DOI: https://doi.org/10.1124/mol.64.1.11
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Allosteric Site on Muscarinic Acetylcholine Receptors: Identification of Two Amino Acids in the Muscarinic M₂ Receptor That Account Entirely for the M₂/M₅ Subtype Selectivities of Some Structurally Diverse Allosteric Ligands in N-Methylscopolamine-Occupied Receptors
Uta Voigtländer, Kirstin Jöhren, Marion Mohr, Alexandra Raasch, Christian Tränkle, Stefan Buller, John Ellis, Hans-Dieter Höltje and Klaus Mohr

Molecular Pharmacology July 2003, 64 (1) 21-31; DOI: https://doi.org/10.1124/mol.64.1.21
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Rescuing the Traffic-Deficient Mutants of Rat μ-Opioid Receptors with Hydrophobic Ligands
Vipa Chaipatikul, Laurie J. Erickson-Herbrandson, Horace H. Loh and Ping-Yee Law

Molecular Pharmacology July 2003, 64 (1) 32-41; DOI: https://doi.org/10.1124/mol.64.1.32
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Transgenic Mouse Models of Human CYP3A4 Gene Regulation
Graham R. Robertson, Jacqueline Field, Bryan Goodwin, Sandra Bierach, Minh Tran, Anne Lehnert and Christopher Liddle

Molecular Pharmacology July 2003, 64 (1) 42-50; DOI: https://doi.org/10.1124/mol.64.1.42
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Bcl-2 Down-Regulation Is a Novel Mechanism of Paclitaxel Resistance
Cristiano Ferlini, Giuseppina Raspaglio, Simona Mozzetti, Mariagrazia Distefano, Flavia Filippetti, Enrica Martinelli, Gabriella Ferrandina, Daniela Gallo, Franco Oreste Ranelletti and Giovanni Scambia

Molecular Pharmacology July 2003, 64 (1) 51-58; DOI: https://doi.org/10.1124/mol.64.1.51
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APETx1, a New Toxin from the Sea Anemone Anthopleura elegantissima, Blocks Voltage-Gated Human Ether-a-go-go–Related Gene Potassium Channels
Sylvie Diochot, Erwann Loret, Thomas Bruhn, Lászlo Béress and Michel Lazdunski

Molecular Pharmacology July 2003, 64 (1) 59-69; DOI: https://doi.org/10.1124/mol.64.1.59
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Molecular Determinants of KCNQ1 Channel Block by a Benzodiazepine
Guiscard Seebohm, Jun Chen, Nathalie Strutz, Chris Culberson, Christian Lerche and Michael C. Sanguinetti

Molecular Pharmacology July 2003, 64 (1) 70-77; DOI: https://doi.org/10.1124/mol.64.1.70
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Positive Allosteric Modulator of the Human 5-HT_2C Receptor
Wha Bin Im, Christopher L. Chio, Glen L. Alberts and Dac M. Dinh

Molecular Pharmacology July 2003, 64 (1) 78-84; DOI: https://doi.org/10.1124/mol.64.1.78
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Anti-Inflammatory Activity of 15-Deoxy-Δ^12,14-PGJ₂ and 2-Cyclopenten-1-one: Role of the Heat Shock Response
Angela Ianaro, Armando Ialenti, Pasquale Maffia, Paola Di Meglio, Massimo Di Rosa and M. Gabriella Santoro

Molecular Pharmacology July 2003, 64 (1) 85-93; DOI: https://doi.org/10.1124/mol.64.1.85
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Molecular Determination of Agouti-Related Protein Binding to Human Melanocortin-4 Receptor
Yingkui Yang, Min Chen, Yumei Lai, Ira Gantz, Aydin Yagmurlu, Keith E. Georgeson and Carroll M. Harmon

Molecular Pharmacology July 2003, 64 (1) 94-103; DOI: https://doi.org/10.1124/mol.64.1.94
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Pharmacological Characterization of the Human P2Y₁₃ Receptor
Frederic Marteau, Emmanuel Le Poul, David Communi, Didier Communi, Catherine Labouret, Pierre Savi, Jean-Marie Boeynaems and Nathalie Suarez Gonzalez

Molecular Pharmacology July 2003, 64 (1) 104-112; DOI: https://doi.org/10.1124/mol.64.1.104
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Regulation of CYP2C11 by Dehydroepiandrosterone and Peroxisome Proliferators: Identification of the Negative Regulatory Region of the Gene
Sharon L. Ripp, K. Cameron Falkner, Mary L. Pendleton, Viola Tamasi and Russell A. Prough

Molecular Pharmacology July 2003, 64 (1) 113-122; DOI: https://doi.org/10.1124/mol.64.1.113
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Jesterone Dimer, a Synthetic Derivative of the Fungal Metabolite Jesterone, Blocks Activation of Transcription Factor Nuclear Factor κB by Inhibiting the Inhibitor of κB Kinase
Mei-Chih Liang, Sujata Bardhan, Chaomin Li, Emily A. Pace, John A. Porco and Thomas D. Gilmore

Molecular Pharmacology July 2003, 64 (1) 123-131; DOI: https://doi.org/10.1124/mol.64.1.123
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Corticotropin Induces the Expression of TREK-1 mRNA and K⁺ Current in Adrenocortical Cells
Judith A. Enyeart, Sanjay Danthi and John J. Enyeart

Molecular Pharmacology July 2003, 64 (1) 132-142; DOI: https://doi.org/10.1124/mol.64.1.132
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[¹²⁵I]A-312110, a Novel High-Affinity 1,4-Dihydropyridine ATP-sensitive K⁺ Channel Opener: Characterization and Pharmacology of Binding
Rachel Davis-Taber, Eduardo J. Molinari, Robert J. Altenbach, Kristi L. Whiteaker, Char-Chang Shieh, Gary Rotert, Steven A. Buckner, John Malysz, Ivan Milicic, Jeffrey S. McDermott, Gary A. Gintant, Michael J. Coghlan, William A. Carroll, Victoria E. Scott and Murali Gopalakrishnan

Molecular Pharmacology July 2003, 64 (1) 143-153; DOI: https://doi.org/10.1124/mol.64.1.143
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Phenobarbital Alters Hepatic Mrp2 Function by Direct and Indirect Interactions
Nita J. Patel, Maciej J. Zamek-Gliszczynski, Peijin Zhang, Yong-Hae Han, Peter L. M. Jansen, Peter J. Meier, Bruno Stieger and Kim L. R. Brouwer

Molecular Pharmacology July 2003, 64 (1) 154-159; DOI: https://doi.org/10.1124/mol.64.1.154
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Colchicine Down-Regulates Cytochrome P450 2B6, 2C8, 2C9, and 3A4 in Human Hepatocytes by Affecting Their Glucocorticoid Receptor-Mediated Regulation
Zdenĕk Dvor̆ák, Martin Modrianský, Lydiane Pichard-Garcia, Patrick Balaguer, Marie-Jose Vilarem, Jitka Ulrichová, Patrick Maurel and Jean-Marc Pascussi

Molecular Pharmacology July 2003, 64 (1) 160-169; DOI: https://doi.org/10.1124/mol.64.1.160
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Generation and Functional Characterization of Arylamine N-Acetyltransferase Nat1/Nat2Double-Knockout Mice
Kim S. Sugamori, Sharon Wong, Andrea Gaedigk, Violeta Yu, Hanan Abramovici, Richard Rozmahel and Denis M. Grant

Molecular Pharmacology July 2003, 64 (1) 170-179; DOI: https://doi.org/10.1124/mol.64.1.170
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Interactions of Orthosteric and Allosteric Ligands with [³H]Dimethyl-W84 at the Common Allosteric Site of Muscarinic M₂ Receptors
Christian Tränkle, Oliver Weyand, Uta Voigtländer, Anita Mynett, Sebastian Lazareno, Nigel J. M. Birdsall and Klaus Mohr

Molecular Pharmacology July 2003, 64 (1) 180-190; DOI: https://doi.org/10.1124/mol.64.1.180

Errata

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Editors' Note regarding “Mechanism of corticotropin-releasing factor type I receptor regulation by nonpeptide antagonists”
Molecular Pharmacology July 2003, 64 (1) 191; DOI: https://doi.org/10.1124/mol.64.1.191
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Correction to “Prostaglandin receptor EP₄ mediates the bone anabolic effects of PGE₂”
Molecular Pharmacology July 2003, 64 (1) 192; DOI: https://doi.org/10.1124/mol.64.1.192
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Correction to “Spatial approximation between a photolabile residue in position 13 of secretin and the amino terminus of the secretin receptor”
Molecular Pharmacology July 2003, 64 (1) 193; DOI: https://doi.org/10.1124/mol.64.1.193

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