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Molecular Pharmacology

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Table of Contents

September 01, 2003; Volume 64,Issue 3

MINIREVIEW

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    Cyclic Nucleotide Phosphodiesterase Activity, Expression, and Targeting in Cells of the Cardiovascular System
    Donald H. Maurice, Daniel Palmer, Douglas G. Tilley, Heather A. Dunkerley, Stuart J. Netherton, Daniel R. Raymond, Hisham S. Elbatarny and Sandra L. Jimmo
    Molecular Pharmacology September 2003, 64 (3) 533-546; DOI: https://doi.org/10.1124/mol.64.3.533

Perspective

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    RGS Protein and G Protein Interactions: A Little Help from Their Friends
    John R. Hepler
    Molecular Pharmacology September 2003, 64 (3) 547-549; DOI: https://doi.org/10.1124/mol.64.3.547

Accelerated Communication

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    Aspartate Aminotransferase Generates Proagonists of the Aryl Hydrocarbon Receptor
    Mark A. Bittinger, Linh P. Nguyen and Christopher A. Bradfield
    Molecular Pharmacology September 2003, 64 (3) 550-556; DOI: https://doi.org/10.1124/mol.64.3.550

Articles

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    Critical Role for Akt1 in the Modulation of Apoptotic Phosphatidylserine Exposure and Microglial Activation
    Jing-Qiong Kang, Zhao Zhong Chong and Kenneth Maiese
    Molecular Pharmacology September 2003, 64 (3) 557-569; DOI: https://doi.org/10.1124/mol.64.3.557
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    Membrane Assembly of the Cannabinoid Receptor 1: Impact of a Long N-Terminal Tail
    Helena Andersson, Aaron M. D'Antona, Debra A. Kendall, Gunnar Von Heijne and Chen-Ni Chin
    Molecular Pharmacology September 2003, 64 (3) 570-577; DOI: https://doi.org/10.1124/mol.64.3.570
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    Prevention of Dopaminergic Neuronal Death by Cyclic AMP in Mixed Neuronal/Glial Mesencephalic Cultures Requires the Repression of Presumptive Astrocytes
    Sophie Mourlevat, Jean-Denis Troadec, Merle Ruberg and Patrick P. Michel
    Molecular Pharmacology September 2003, 64 (3) 578-586; DOI: https://doi.org/10.1124/mol.64.3.578
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    Recruitment of RGS2 and RGS4 to the Plasma Membrane by G Proteins and Receptors Reflects Functional Interactions
    Anju Anne Roy, Kara E. Lemberg and Peter Chidiac
    Molecular Pharmacology September 2003, 64 (3) 587-593; DOI: https://doi.org/10.1124/mol.64.3.587
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    Mouse κ-Opioid Receptor mRNA Differential Transport in Neurons
    Jing Bi, Xinli Hu, Horace H. Loh and Li-Na Wei
    Molecular Pharmacology September 2003, 64 (3) 594-599; DOI: https://doi.org/10.1124/mol.64.3.594
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    Metal-Dependent Inhibition of HIV-1 Integrase by β-Diketo Acids and Resistance of the Soluble Double-Mutant (F185K/C280S)
    Christophe Marchand, Allison A. Johnson, Rajeshri G. Karki, Godwin C. G. Pais, Xuechun Zhang, Kiriana Cowansage, Tapan A. Patel, Marc C. Nicklaus, Terrence R. Burke and Yves Pommier
    Molecular Pharmacology September 2003, 64 (3) 600-609; DOI: https://doi.org/10.1124/mol.64.3.600
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    Breast Cancer Resistance Protein Exports Sulfated Estrogens but Not Free Estrogens
    Yasuo Imai, Sakiyo Asada, Satomi Tsukahara, Etsuko Ishikawa, Takashi Tsuruo and Yoshikazu Sugimoto
    Molecular Pharmacology September 2003, 64 (3) 610-618; DOI: https://doi.org/10.1124/mol.64.3.610
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    l-DOPA Treatment Modulates Nicotinic Receptors in Monkey Striatum
    Maryka Quik, Tanuja Bordia, Michaella Okihara, Hong Fan, Michael J. Marks, J. Michael McIntosh and Paul Whiteaker
    Molecular Pharmacology September 2003, 64 (3) 619-628; DOI: https://doi.org/10.1124/mol.64.3.619
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    Involvement of Intramolecular Interactions in the Regulation of G Protein-Coupled Receptor Kinase 2
    Susana Sarnago, Ramón Roca, Antonio De Blasi, Alfonso Valencia, Federico Mayor and Cristina Murga
    Molecular Pharmacology September 2003, 64 (3) 629-639; DOI: https://doi.org/10.1124/mol.64.3.629
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    Adenosine-A2a Receptor Down-Regulates Cerebral Smooth Muscle L-Type Ca2+ Channel Activity via Protein Tyrosine Phosphatase, Not cAMP-Dependent Protein Kinase
    Katrina Murphy, Volodymyr Gerzanich, Hui Zhou, Svetlana Ivanova, Yafeng Dong, Gloria Hoffman, G. Alexander West, H. Richard Winn and J. Marc Simard
    Molecular Pharmacology September 2003, 64 (3) 640-649; DOI: https://doi.org/10.1124/mol.64.3.640
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    Agonist-Induced Conformational Changes in the Extracellular Domain of α7 Nicotinic Acetylcholine Receptors
    Lisa K. Lyford, Adrian D. Sproul, Donnie Eddins, James T. McLaughlin and Robert L. Rosenberg
    Molecular Pharmacology September 2003, 64 (3) 650-658; DOI: https://doi.org/10.1124/mol.64.3.650
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    Genetic Polymorphism of CYP1A2 in Ethiopians Affecting Induction and Expression: Characterization of Novel Haplotypes with Single-Nucleotide Polymorphisms in Intron 1
    Eleni Aklillu, Juan Antonio Carrillo, Eyasu Makonnen, Karin Hellman, Marià Pitarque, Leif Bertilsson and Magnus Ingelman-Sundberg
    Molecular Pharmacology September 2003, 64 (3) 659-669; DOI: https://doi.org/10.1124/mol.64.3.659
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    The Metabolites of the Cardioprotective Drug Dexrazoxane Do Not Protect Myocytes from Doxorubicin-Induced Cytotoxicity
    Brian B. Hasinoff, Patricia E. Schroeder and Daywin Patel
    Molecular Pharmacology September 2003, 64 (3) 670-678; DOI: https://doi.org/10.1124/mol.64.3.670
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    Influence of Agonist Efficacy and Receptor Phosphorylation on Antagonist Affinity Measurements: Differences between Second Messenger and Reporter Gene Responses
    Jillian G. Baker, Ian P. Hall and Stephen J. Hill
    Molecular Pharmacology September 2003, 64 (3) 679-688; DOI: https://doi.org/10.1124/mol.64.3.679
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    Characterization of Ca2+ Channels and G Proteins Involved in Arachidonic Acid Release by Endothelin-1/EndothelinA Receptor
    Yoshifumi Kawanabe, Kazuhiko Nozaki, Nobuo Hashimoto and Tomoh Masaki
    Molecular Pharmacology September 2003, 64 (3) 689-695; DOI: https://doi.org/10.1124/mol.64.3.689
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    Low Molecular Weight Fucoidan and Heparin Enhance the Basic Fibroblast Growth Factor-Induced Tube Formation of Endothelial Cells through Heparan Sulfate-Dependent α6 Overexpression
    Delphine Chabut, Anne-Marie Fischer, Sylvia Colliec-Jouault, Ingrid Laurendeau, Sabine Matou, Bernard Le Bonniec and Dominique Helley
    Molecular Pharmacology September 2003, 64 (3) 696-702; DOI: https://doi.org/10.1124/mol.64.3.696
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    Stargazin Differentially Controls the Trafficking of α-Amino-3-hydroxyl-5-methyl-4-isoxazolepropionate and Kainate Receptors
    Lu Chen, Alaa El-Husseini, Susumu Tomita, David S. Bredt and Roger A. Nicoll
    Molecular Pharmacology September 2003, 64 (3) 703-706; DOI: https://doi.org/10.1124/mol.64.3.703
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    5-Fluorouracil Blocks Transforming Growth Factor-β–Induced α2 Type I Collagen Gene (COL1A2) Expression in Human Fibroblasts via c-Jun NH2-Terminal Kinase/Activator Protein-1 Activation
    Jeanne Wendling, Aimé Marchand, Alain Mauviel and Franck Verrecchia
    Molecular Pharmacology September 2003, 64 (3) 707-713; DOI: https://doi.org/10.1124/mol.64.3.707
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    Biochemical, Cytotoxic, and Genotoxic Effects of ES936, a Mechanism-Based Inhibitor of NAD(P)H:quinone Oxidoreductase 1, in Cellular Systems
    Donna L. Dehn, David Siegel, Elizabeth Swann, Christopher J. Moody and David Ross
    Molecular Pharmacology September 2003, 64 (3) 714-720; DOI: https://doi.org/10.1124/mol.64.3.714
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    Differential Signaling of Formyl Peptide Receptor-Like 1 by Trp-Lys-Tyr-Met-Val-Met-CONH2 or Lipoxin A4 in Human Neutrophils
    Yoe-Sik Bae, Jun Chul Park, Rong He, Richard D. Ye, Jong-Young Kwak, Pann-Ghill Suh and Sung Ho Ryu
    Molecular Pharmacology September 2003, 64 (3) 721-730; DOI: https://doi.org/10.1124/mol.64.3.721
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    A Family of Highly Selective Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 5
    Julie A. O'Brien, Wei Lemaire, Tsing-Bau Chen, Raymond S. L. Chang, Marlene A. Jacobson, Sookhee N. Ha, Craig W. Lindsley, Hervé J. Schaffhauser, Cyrille Sur, Douglas J. Pettibone, P. Jeffrey Conn and David L. Williams
    Molecular Pharmacology September 2003, 64 (3) 731-740; DOI: https://doi.org/10.1124/mol.64.3.731
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    Altered Gating and Local Anesthetic Block Mediated by Residues in the I-S6 and II-S6 Transmembrane Segments of Voltage-Dependent Na+ Channels
    Andrei Kondratiev and Gordon F. Tomaselli
    Molecular Pharmacology September 2003, 64 (3) 741-752; DOI: https://doi.org/10.1124/mol.64.3.741
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    Receptor Subtype-Dependent Positive and Negative Modulation of GABAA Receptor Function by Niflumic Acid, a Nonsteroidal Anti-Inflammatory Drug
    Saku T. Sinkkonen, Salla Mansikkamäki, Tommi Möykkynen, Hartmut Lüddens, Mikko Uusi-Oukari and Esa R. Korpi
    Molecular Pharmacology September 2003, 64 (3) 753-763; DOI: https://doi.org/10.1124/mol.64.3.753
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    Down-Regulation of Acyl-CoA Oxidase Gene Expression in Heart of Troglitazone-Treated Mice through a Mechanism Involving Chicken Ovalbumin Upstream Promoter Transcription Factor II
    Àgatha Cabrero, Mireia Jové, Anna Planavila, Manuel Merlos, Juan C. Laguna and Manuel Vázquez-Carrera
    Molecular Pharmacology September 2003, 64 (3) 764-772; DOI: https://doi.org/10.1124/mol.64.3.764
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    Signaling Pathways for Monocyte Chemoattractant Protein 1-Mediated Extracellular Signal-Regulated Kinase Activation
    M. Carmen Jiménez-Sainz, Beate Fast, Federico Mayor and Anna M. Aragay
    Molecular Pharmacology September 2003, 64 (3) 773-782; DOI: https://doi.org/10.1124/mol.64.3.773

Errata

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    Correction to “Prostacylin receptor activation inhibits proliferation of aortic smooth muscle cells by regulating cAMP response element-binding protein- and pocket protein-dependent cyclin A gene expression”
    Molecular Pharmacology September 2003, 64 (3) 783; DOI: https://doi.org/10.1124/mol.64.3.783
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    Correction to “Enhancement of long-term potentiation by a potent nitric oxide-guanylyl cyclase activator, 3-(5-hydroxymethyl-2-furyl)-1-benzyl-indazole”
    Molecular Pharmacology September 2003, 64 (3) 784; DOI: https://doi.org/10.1124/mol.64.3.784
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Molecular Pharmacology: 64 (3)
Molecular Pharmacology
Vol. 64, Issue 3
1 Sep 2003
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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