Table of Contents

Articles

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  Expression of the Aflatoxin B₁-8,9-Epoxide-Metabolizing Murine Glutathione S-Transferase A3 Subunit Is Regulated by the Nrf2 Transcription Factor through an Antioxidant Response Element

  Ian R. Jowsey, Qing Jiang, Ken Itoh, Masayuki Yamamoto and John D. Hayes

  Molecular Pharmacology November 2003, 64 (5) 1018-1028; DOI: https://doi.org/10.1124/mol.64.5.1018
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  Inhibition of Vascular Endothelial Growth Factor-Induced Angiogenesis by Resveratrol through Interruption of Src-Dependent Vascular Endothelial Cadherin Tyrosine Phosphorylation

  Ming-Tsan Lin, Men-Luh Yen, Chia-Yi Lin and Min-Liang Kuo

  Molecular Pharmacology November 2003, 64 (5) 1029-1036; DOI: https://doi.org/10.1124/mol.64.5.1029
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  Different Affinities of Inhibitors to the Outwardly and Inwardly Directed Substrate Binding Site of Organic Cation Transporter 2

  Christopher Volk, Valentin Gorboulev, Thomas Budiman, Georg Nagel and Hermann Koepsell

  Molecular Pharmacology November 2003, 64 (5) 1037-1047; DOI: https://doi.org/10.1124/mol.64.5.1037
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  The Third Intracellular Loop and the Carboxyl Terminus of β₂-Adrenergic Receptor Confer Spontaneous Activity of the Receptor

  Khalid Chakir, Yang Xiang, Dongmei Yang, Sheng-Jun Zhang, Heping Cheng, Brian K. Kobilka and Rui-Ping Xiao

  Molecular Pharmacology November 2003, 64 (5) 1048-1058; DOI: https://doi.org/10.1124/mol.64.5.1048
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  Specificity of G Protein-Coupled Receptor Kinase 6-Mediated Phosphorylation and Regulation of Single-Cell M₃ Muscarinic Acetylcholine Receptor Signaling

  Jonathon M. Willets, Rajendra Mistry, Stefan R. Nahorski and R. A. John Challiss

  Molecular Pharmacology November 2003, 64 (5) 1059-1068; DOI: https://doi.org/10.1124/mol.64.5.1059
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  Cytoplasmic Accumulation of the Nuclear Receptor CAR by a Tetratricopeptide Repeat Protein in HepG2 Cells

  Kaoru Kobayashi, Tatsuya Sueyoshi, Kaoru Inoue, Rick Moore and Masahiko Negishi

  Molecular Pharmacology November 2003, 64 (5) 1069-1075; DOI: https://doi.org/10.1124/mol.64.5.1069
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  Inhibition of Invasion and Angiogenesis by Zinc-Chelating Agent Disulfiram

  Shine-Gwo Shian, Yu-Rung Kao, Felicia Ying-Hsiueh Wu and Cheng-Wen Wu

  Molecular Pharmacology November 2003, 64 (5) 1076-1084; DOI: https://doi.org/10.1124/mol.64.5.1076
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  Interaction of G Protein β Subunit with Inward Rectifier K⁺ Channel Kir3

  Qi Zhao, Takeharu Kawano, Hiroko Nakata, Yasuko Nakajima, Shigehiro Nakajima and Tohru Kozasa

  Molecular Pharmacology November 2003, 64 (5) 1085-1091; DOI: https://doi.org/10.1124/mol.64.5.1085
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  Interaction Between the μ Opioid Receptor and Filamin A Is Involved in Receptor Regulation and Trafficking

  Irma Onoprishvili, Matthew L. Andria, Hal K. Kramer, Natasa Ancevska-Taneva, Jacob M. Hiller and Eric J. Simon

  Molecular Pharmacology November 2003, 64 (5) 1092-1100; DOI: https://doi.org/10.1124/mol.64.5.1092
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  Acquired Cellular Resistance to Flavopiridol in a Human Colon Carcinoma Cell Line Involves Up-Regulation of the Telomerase Catalytic Subunit and Telomere Elongation. Sensitivity of Resistant Cells to Combination Treatment with a Telomerase Inhibitor

  Christopher M. Incles, Christoph M. Schultes, Lloyd R. Kelland and Stephen Neidle

  Molecular Pharmacology November 2003, 64 (5) 1101-1108; DOI: https://doi.org/10.1124/mol.64.5.1101
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  Role of Mitochondrial Aldehyde Dehydrogenase in Nitrate Tolerance

  Jon DiFabio, Yanbin Ji, Vasilis Vasiliou, Gregory R. J. Thatcher and Brian M. Bennett

  Molecular Pharmacology November 2003, 64 (5) 1109-1116; DOI: https://doi.org/10.1124/mol.64.5.1109
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  β₂-Adrenergic Signaling in Human Heart: Shift from the Cyclic AMP to the Arachidonic Acid Pathway

  Catherine Pavoine, Niloufar Behforouz, Chantal Gauthier, Sabine Le Gouvello, Françoise Roudot-Thoraval, Catherine Rücker Martin, André Pawlak, Chloé Féral, Nicole Defer, Rémi Houel, Sandrine Magne, Aissata Amadou, Daniel Loisance, Philippe Duvaldestin and Françoise Pecker

  Molecular Pharmacology November 2003, 64 (5) 1117-1125; DOI: https://doi.org/10.1124/mol.64.5.1117
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  Up-Regulation of α_1B-Adrenergic Receptors with Defects in G Protein Coupling: Ligand-Induced Protection from Receptor Instability

  Steven C. Prinster, Nancy A. Schulte, Megan R. Collins and Myron L. Toews

  Molecular Pharmacology November 2003, 64 (5) 1126-1135; DOI: https://doi.org/10.1124/mol.64.5.1126
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  Effect of Glutathione Depletion on Sites and Topology of Superoxide and Hydrogen Peroxide Production in Mitochondria

  Derick Han, Raffaella Canali, Daniel Rettori and Neil Kaplowitz

  Molecular Pharmacology November 2003, 64 (5) 1136-1144; DOI: https://doi.org/10.1124/mol.64.5.1136
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  An N-Terminal Histidine Is the Primary Determinant of α Subunit-Dependent Cu²⁺ Sensitivity of αβ3γ2L GABA_A Receptors

  Heejeong Kim and Robert L. Macdonald

  Molecular Pharmacology November 2003, 64 (5) 1145-1152; DOI: https://doi.org/10.1124/mol.64.5.1145
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  Small Interfering RNA Suppression of Polyamine Analog-Induced Spermidine/Spermine N¹-Acetyltransferase

  Ying Chen, Debora L. Kramer, Jason Jell, Slavoljub Vujcic and Carl W. Porter

  Molecular Pharmacology November 2003, 64 (5) 1153-1159; DOI: https://doi.org/10.1124/mol.64.5.1153
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  The Peptide KLVFF-K₆ Promotes β-Amyloid(1–40) Protofibril Growth by Association but Does Not Alter Protofibril Effects on Cellular Reduction of 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide (MTT)

  Melissa A. Moss, Michael R. Nichols, Dana Kim Reed, Jan H. Hoh and Terrone L. Rosenberry

  Molecular Pharmacology November 2003, 64 (5) 1160-1168; DOI: https://doi.org/10.1124/mol.64.5.1160
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  Inhibition of Interleukin-4 Production in CD4⁺ T Cells by Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) Ligands: Involvement of Physical Association between PPAR-γ and the Nuclear Factor of Activated T Cells Transcription Factor

  Su Wol Chung, Bok Yun Kang and Tae Sung Kim

  Molecular Pharmacology November 2003, 64 (5) 1169-1179; DOI: https://doi.org/10.1124/mol.64.5.1169
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  Regulation of the Rat Phenylethanolamine N-Methyltransferase Gene by Transcription Factors Sp1 and MAZ

  Song Her, Robert Claycomb, T. C. Tai and Dona L. Wong

  Molecular Pharmacology November 2003, 64 (5) 1180-1188; DOI: https://doi.org/10.1124/mol.64.5.1180
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  Ceramide Is Involved in R(+)-Methanandamide-Induced Cyclooxygenase-2 Expression in Human Neuroglioma Cells

  Robert Ramer, Ulrike Weinzierl, Bianca Schwind, Kay Brune and Burkhard Hinz

  Molecular Pharmacology November 2003, 64 (5) 1189-1198; DOI: https://doi.org/10.1124/mol.64.5.1189
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  Common Signaling Pathways Link Activation of Murine PAR-1, LPA, and S1P Receptors to Proliferation of Astrocytes

  Scott D. Sorensen, Olivier Nicole, Richard D. Peavy, Lisa M. Montoya, C. Justin Lee, T. J. Murphy, Stephen F. Traynelis and John R. Hepler

  Molecular Pharmacology November 2003, 64 (5) 1199-1209; DOI: https://doi.org/10.1124/mol.64.5.1199
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  Purification and Functional Reconstitution of the Human P2Y₁₂ Receptor

  Erik T. Bodor, Gary L. Waldo, Shelley B. Hooks, James Corbitt, Jose L. Boyer and T. Kendall Harden

  Molecular Pharmacology November 2003, 64 (5) 1210-1216; DOI: https://doi.org/10.1124/mol.64.5.1210
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  The Allosteric Potentiation of Nicotinic Acetylcholine Receptors by Galantamine Is Transduced into Cellular Responses in Neurons: Ca²⁺ Signals and Neurotransmitter Release.

  Federico A. Dajas-Bailador, Kaisa Heimala and Susan Wonnacott

  Molecular Pharmacology November 2003, 64 (5) 1217-1226; DOI: https://doi.org/10.1124/mol.64.5.1217
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  Ligand-Receptor-G-Protein Molecular Assemblies on Beads for Mechanistic Studies and Screening by Flow Cytometry

  Peter C. Simons, Mei Shi, Terry Foutz, Daniel F. Cimino, Jeremy Lewis, Tione Buranda, William K. Lim, Richard R. Neubig, William E. McIntire, James Garrison, Eric Prossnitz and Larry A. Sklar

  Molecular Pharmacology November 2003, 64 (5) 1227-1238; DOI: https://doi.org/10.1124/mol.64.5.1227
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  Selective Interaction of ARF1 with the Carboxy-Terminal Tail Domain of the 5-HT_2A Receptor

  Derek N. Robertson, Melanie S. Johnson, Louise O. Moggach, Pamela J. Holland, Eve M. Lutz and Rory Mitchell

  Molecular Pharmacology November 2003, 64 (5) 1239-1250; DOI: https://doi.org/10.1124/mol.64.5.1239
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  Expression of the Angiogenic Factor Thymidine Phosphorylase in THP-1 Monocytes: Induction by Autocrine Tumor Necrosis Factor-α and Inhibition by Aspirin

  Geng Hui Zhu and Edward L. Schwartz

  Molecular Pharmacology November 2003, 64 (5) 1251-1258; DOI: https://doi.org/10.1124/mol.64.5.1251
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  Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions

  Mario Muredda, Ken-Ichi Nunoya, Ruth A. Burtch-Wright, Ebba U. Kurz, Susan P. C. Cole and Roger G. Deeley

  Molecular Pharmacology November 2003, 64 (5) 1259-1269; DOI: https://doi.org/10.1124/mol.64.5.1259
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  Correction to “Rescuing the traffic-deficient mutants of rat μ-opioid receptors with hydrophobic ligands”

  Molecular Pharmacology November 2003, 64 (5) 1270; DOI: https://doi.org/10.1124/mol.64.5.1270