Molecular Pharmacology: 64 (5)

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About the cover: Structure of poly(ADP-ribose) polymerase-1 (PARP-1). Ribbon representation of chicken's PARP-1 catalytic fragment (C-terminal end, amino acids 662 to 1014), which was cocrystallized with the NAD analog carba-NAD. See the article by Nguewa et al. on 1007 of this issue.

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SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module

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