Table of Contents

Articles

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  Design of a High-Affinity Competitive Antagonist of the Vanilloid Receptor Selective for the Calcium Entry-Linked Receptor Population

  Attila Tóth, Peter M. Blumberg, Zili Chen and Alan P. Kozikowski

  Molecular Pharmacology February 2004, 65 (2) 282-291; DOI: https://doi.org/10.1124/mol.65.2.282
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  A Novel Constitutive Androstane Receptor-Mediated and CYP3A-Independent Pathway of Bile Acid Detoxification

  Simrat P. S. Saini, Junichiro Sonoda, Li Xu, David Toma, Hirdesh Uppal, Ying Mu, Songrong Ren, David D. Moore, Ronald M. Evans and Wen Xie

  Molecular Pharmacology February 2004, 65 (2) 292-300; DOI: https://doi.org/10.1124/mol.65.2.292
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  Multiple Pharmacophores for the Investigation of Human UDP-Glucuronosyltransferase Isoform Substrate Selectivity

  Michael J. Sorich, John O. Miners, Ross A. McKinnon and Paul A. Smith

  Molecular Pharmacology February 2004, 65 (2) 301-308; DOI: https://doi.org/10.1124/mol.65.2.301
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  Peroxisome Proliferator-Activated Receptor-γ-Independent Repression of Collagenase Gene Expression by 2-Cyano-3,12-dioxooleana-1,9-dien-28-oic Acid and Prostaglandin 15-Deoxy-Δ(12,14) J₂: A Role for Smad Signaling

  Kimberlee S. Mix, Charles I. Coon, Evan D. Rosen, Nanjoo Suh, Michael B. Sporn and Constance E. Brinckerhoff

  Molecular Pharmacology February 2004, 65 (2) 309-318; DOI: https://doi.org/10.1124/mol.65.2.309
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  Nitric Oxide Regulates c-fos Expression in Nucleus Tractus Solitarii Induced by Baroreceptor Activation via cGMP-Dependent Protein Kinase and cAMP Response Element-Binding Protein Phosphorylation

  Samuel H. H. Chan, Kui-Fen Chang, Chen-Chun Ou and Julie Y. H. Chan

  Molecular Pharmacology February 2004, 65 (2) 319-325; DOI: https://doi.org/10.1124/mol.65.2.319
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  Identification of a Novel Polymorphic Enhancer of the Human CYP3A4 Gene

  Keiko Matsumura, Tetsuya Saito, Yoshiki Takahashi, Takeshi Ozeki, Kazuma Kiyotani, Masaki Fujieda, Hiroshi Yamazaki, Hideo Kunitoh and Tetsuya Kamataki

  Molecular Pharmacology February 2004, 65 (2) 326-334; DOI: https://doi.org/10.1124/mol.65.2.326
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  New Molecular Determinants Controlling the Accessibility of Ouabain to Its Binding Site in Human Na,K-ATPase α Isoforms

  Gilles Crambert, Daniele Schaer, Sophie Roy and Käthi Geering

  Molecular Pharmacology February 2004, 65 (2) 335-341; DOI: https://doi.org/10.1124/mol.65.2.335
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  Proteasome Inhibitors Induce Inhibitory κB (IκB) Kinase Activation, IκBα Degradation, and Nuclear Factor κB Activation in HT-29 Cells

  Zoltán H. Németh, Hector R. Wong, Kelli Odoms, Edwin A. Deitch, Csaba Szabó, E. Sylvester Vizi and György Haskó

  Molecular Pharmacology February 2004, 65 (2) 342-349; DOI: https://doi.org/10.1124/mol.65.2.342
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  Barbiturates Directly Inhibit the Calmodulin/Calcineurin Complex: a Novel Mechanism of Inhibition of Nuclear Factor of Activated T Cells

  Matjaz Humar, Soeren E. Pischke, Torsten Loop, Alexander Hoetzel, Rene Schmidt, Christoph Klaas, Heike L. Pahl, Klaus K. Geiger and Benedikt H. J. Pannen

  Molecular Pharmacology February 2004, 65 (2) 350-361; DOI: https://doi.org/10.1124/mol.65.2.350
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  The Type 1 Angiotensin II Receptor Tail Affects Receptor Targeting, Internalization, and Membrane Fusion Properties

  Bryan N. Becker, Hui-fang Cheng, Timothy G. Hammond and Raymond C. Harris

  Molecular Pharmacology February 2004, 65 (2) 362-369; DOI: https://doi.org/10.1124/mol.65.2.362
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  Use-Dependent Inhibition of the N-Methyl-D-aspartate Currents by Felbamate: a Gating Modifier with Selective Binding to the Desensitized Channels

  Chung-Chin Kuo, Bei-Jung Lin, Huai-Ren Chang and Chi-Pan Hsieh

  Molecular Pharmacology February 2004, 65 (2) 370-380; DOI: https://doi.org/10.1124/mol.65.2.370
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  Differential Modulation of Ca_V2.3 Ca²⁺ Channels by Gαq/11-Coupled Muscarinic Receptors

  R. A. Bannister, K. Melliti and B. A. Adams

  Molecular Pharmacology February 2004, 65 (2) 381-388; DOI: https://doi.org/10.1124/mol.65.2.381
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  Bucillamine Induces the Synthesis of Vascular Endothelial Growth Factor Dose-Dependently in Systemic Sclerosis Fibroblasts via Nuclear Factor-κB and Simian Virus 40 Promoter Factor 1 Pathways

  Jörg H. W. Distler, Claudia Hagen, Astrid Hirth, Ulf Müller-Ladner, Hanns M. Lorenz, Angela del Rosso, Beat A. Michel, Renate E. Gay, Ratanavadee Nanagara, Kusuki Nishioka, Marco Matucci-Cerinic, Joachim R. Kalden, Steffen Gay and Oliver Distler

  Molecular Pharmacology February 2004, 65 (2) 389-399; DOI: https://doi.org/10.1124/mol.65.2.389
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  Reverse Transcriptase Activity of Hepatitis B Virus (HBV) DNA Polymerase within Core Capsid: Interaction with Deoxynucleoside Triphosphates and Anti-HBV l-Deoxynucleoside Analog Triphosphates

  Wing Lam, Ying Li, Jieh-Yuan Liou, Ginger E. Dutschman and Yung-chi Cheng

  Molecular Pharmacology February 2004, 65 (2) 400-406; DOI: https://doi.org/10.1124/mol.65.2.400
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  Vanadate Is a Potent Activator of Endothelial Nitric-Oxide Synthase: Evidence for the Role of the Serine/Threonine Kinase Akt and the 90-kDa Heat Shock Protein

  Andreas Papapetropoulos, David Fulton, Michelle I. Lin, Jason Fontana, Timothy J. McCabe, Stefan Zoellner, Guillermo García-Cardeña, Zongmin Zhou, Jean-Phillipe Gratton and William C. Sessa

  Molecular Pharmacology February 2004, 65 (2) 407-415; DOI: https://doi.org/10.1124/mol.65.2.407
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  Different Structural Requirements of the Ligand Binding Domain of the Aryl Hydrocarbon Receptor for High- and Low-Affinity Ligand Binding and Receptor Activation

  Maria Backlund and Magnus Ingelman-Sundberg

  Molecular Pharmacology February 2004, 65 (2) 416-425; DOI: https://doi.org/10.1124/mol.65.2.416
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  Agonist Binding and Gq-Stimulating Activities of the Purified Human P2Y₁ Receptor

  Gary L. Waldo and T. Kendall Harden

  Molecular Pharmacology February 2004, 65 (2) 426-436; DOI: https://doi.org/10.1124/mol.65.2.426
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  Systemic Morphine Administration Suppresses Genes Involved in Antigen Presentation

  Karen Beagles, Anton Wellstein and Barbara Bayer

  Molecular Pharmacology February 2004, 65 (2) 437-442; DOI: https://doi.org/10.1124/mol.65.2.437
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  Two-Pore-Domain K⁺ Channels Are a Novel Target for the Anesthetic Gases Xenon, Nitrous Oxide, and Cyclopropane

  Marco Gruss, Trevor J. Bushell, Damian P. Bright, William R. Lieb, Alistair Mathie and Nicholas P. Franks

  Molecular Pharmacology February 2004, 65 (2) 443-452; DOI: https://doi.org/10.1124/mol.65.2.443
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  Pharmacological Properties of α9α10 Nicotinic Acetylcholine Receptors Revealed by Heterologous Expression of Subunit Chimeras

  Elizabeth R. Baker, Ruud Zwart, Emanuele Sher and Neil S. Millar

  Molecular Pharmacology February 2004, 65 (2) 453-460; DOI: https://doi.org/10.1124/mol.65.2.453
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  Cytochrome P4501A1 Promotes G₁ Phase Cell Cycle Progression by Controlling Aryl Hydrocarbon Receptor Activity

  Aviva Levine-Fridman, Li Chen and Cornelis J. Elferink

  Molecular Pharmacology February 2004, 65 (2) 461-469; DOI: https://doi.org/10.1124/mol.65.2.461
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  Aspirin-Mediated COX-2 Transcript Stabilization via Sustained p38 Activation in Human Intestinal Myofibroblasts

  Randy C. Mifflin, Jamal I. Saada, John F. Di Mari, John D. Valentich, Patrick A. Adegboyega and Don W. Powell

  Molecular Pharmacology February 2004, 65 (2) 470-478; DOI: https://doi.org/10.1124/mol.65.2.470