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Research ArticleArticle

Protein Adduct-Trapping by Hydrazinophthalazine Drugs: Mechanisms of Cytoprotection Against Acrolein-Mediated Toxicity

Philip C. Burcham, Frank R. Fontaine, Lisa M. Kaminskas, Dennis R. Petersen and Simon M. Pyke
Molecular Pharmacology March 2004, 65 (3) 655-664; DOI: https://doi.org/10.1124/mol.65.3.655

Article Information

vol. 65 no. 3 655-664
DOI 
https://doi.org/10.1124/mol.65.3.655
PubMed 
14978244
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 15, 2003
  • Accepted November 20, 2003
  • Published online February 19, 2004.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Philip C. Burcham,
  2. Frank R. Fontaine,
  3. Lisa M. Kaminskas,
  4. Dennis R. Petersen and
  5. Simon M. Pyke
  1. Molecular Toxicology Research Group, Department of Clinical & Experimental Pharmacology (P.C.B., F.R.F., L.M.K.), and Department of Chemistry (L.M.K., S.M.P.), the University of Adelaide, Adelaide, South Australia, Australia; and Department of Pharmaceutical Sciences, the University of Colorado Health Science Center, Denver, Colorado (D.R.P.)
  1. Address correspondence to:
    Dr. Philip C Burcham, Molecular Toxicology Research Group, Department of Clinical and Experimental Pharmacology, The University of Adelaide, Adelaide, SA 5005, Australia. E-mail: philip.burcham{at}adelaide.edu.au
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Research ArticleArticle

Protein Adduct-Trapping by Hydrazinophthalazine Drugs: Mechanisms of Cytoprotection Against Acrolein-Mediated Toxicity

Philip C. Burcham, Frank R. Fontaine, Lisa M. Kaminskas, Dennis R. Petersen and Simon M. Pyke
Molecular Pharmacology March 1, 2004, 65 (3) 655-664; DOI: https://doi.org/10.1124/mol.65.3.655
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