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Phorbol 12-Myristate 13-Acetate Protects Jurkat Cells from Methylglyoxal-Induced Apoptosis by Preventing c-Jun N-Terminal Kinase-Mediated Leakage of Cytochrome c in an Extracellular Signal-Regulated Kinase-Dependent Manner

Yoshikazu Takagi, Jun Du, Xiu-Yang Ma, Izumi Nakashima and Fumihiko Nagase
Molecular Pharmacology March 2004, 65 (3) 778-787; DOI: https://doi.org/10.1124/mol.65.3.778

Article Information

vol. 65 no. 3 778-787
DOI 
https://doi.org/10.1124/mol.65.3.778
PubMed 
14978257
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received August 4, 2003
  • Accepted November 20, 2003
  • Published online February 19, 2004.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yoshikazu Takagi,
  2. Jun Du,
  3. Xiu-Yang Ma,
  4. Izumi Nakashima and
  5. Fumihiko Nagase
  1. Department of Medical Technology, Nagoya University School of Health Sciences, Aichi, Japan (Y.T., J.D., X.-Y.M., F.N.); and Department of Immunology, Nagoya University Graduate School of Medicine, Aichi, Japan (X.-Y.M., I.N.)
  1. Address correspondence to:
    Dr. Fumihiko Nagase, Department of Medical Technology, Nagoya University School of Health Sciences, 1-20 Daikominami-1-chome, Higashi-ku, Nagoya 461-8673, Japan. E-mail: nagase{at}met.nagoya-u.ac.jp
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Research ArticleArticle

Phorbol 12-Myristate 13-Acetate Protects Jurkat Cells from Methylglyoxal-Induced Apoptosis by Preventing c-Jun N-Terminal Kinase-Mediated Leakage of Cytochrome c in an Extracellular Signal-Regulated Kinase-Dependent Manner

Yoshikazu Takagi, Jun Du, Xiu-Yang Ma, Izumi Nakashima and Fumihiko Nagase
Molecular Pharmacology March 1, 2004, 65 (3) 778-787; DOI: https://doi.org/10.1124/mol.65.3.778
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