Table of Contents

Articles

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  Src and Cas Are Essentially but Differentially Involved in Angiotensin II-Stimulated Migration of Vascular Smooth Muscle Cells via Extracellular Signal-Regulated Kinase 1/2 and c-Jun NH₂-Terminal Kinase Activation

  Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Shoji Kagami, Yuki Izawa, Yoshiko Fujita, Nermin Ali, Yasuhisa Kanematsu, Kazunori Toida, Kazunori Ishimura and Toshiaki Tamaki

  Molecular Pharmacology April 2004, 65 (4) 832-841; DOI: https://doi.org/10.1124/mol.65.4.832
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  Differential Roles of Arg97, Asp293, and Arg108 in Enzyme Stability and Substrate Specificity of CYP2C9

  Leslie J. Dickmann, Charles W. Locuson, Jeffrey P. Jones and Allan E. Rettie

  Molecular Pharmacology April 2004, 65 (4) 842-850; DOI: https://doi.org/10.1124/mol.65.4.842
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  Nitric Oxide (NO) Scavenging and NO Protecting Effects of Quercetin and Their Biological Significance in Vascular Smooth Muscle

  Gustavo López-López, Laura Moreno, Angel Cogolludo, Milagros Galisteo, Manuel Ibarra, Juan Duarte, Federica Lodi, Juan Tamargo and Francisco Perez-Vizcaino

  Molecular Pharmacology April 2004, 65 (4) 851-859; DOI: https://doi.org/10.1124/mol.65.4.851
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  Crystal Structures of the Mitochondrial Deoxyribonucleotidase in Complex with Two Specific Inhibitors

  Agnes Rinaldo-Matthis, Chiara Rampazzo, Jan Balzarini, Peter Reichard, Vera Bianchi and Pär Nordlund

  Molecular Pharmacology April 2004, 65 (4) 860-867; DOI: https://doi.org/10.1124/mol.65.4.860
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  Potent Cyclic Antagonists of the Complement C5a Receptor on Human Polymorphonuclear Leukocytes. Relationships between Structures and Activity

  Darren R. March, Lavinia M. Proctor, Martin J. Stoermer, Robert Sbaglia, Giovanni Abbenante, Robert C. Reid, Trent M. Woodruff, Khemar Wadi, Natalii Paczkowski, Joel D. A. Tyndall, Stephen M. Taylor and David P. Fairlie

  Molecular Pharmacology April 2004, 65 (4) 868-879; DOI: https://doi.org/10.1124/mol.65.4.868
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  Rapamycin Effects Transcriptional Programs in Smooth Muscle Cells Controlling Proliferative and Inflammatory Properties

  Dietlind Zohlnhöfer, Thomas G. Nührenberg, Franz-Josef Neumann, Thomas Richter, Andreas E. May, Roland Schmidt, Katja Denker, Matthias A. Clauss, Albert Schömig and Patrick A. Baeuerle

  Molecular Pharmacology April 2004, 65 (4) 880-889; DOI: https://doi.org/10.1124/mol.65.4.880
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  Inhibition of Tumor Necrosis Factor-α-Converting Enzyme by a Selective Antagonist Protects Brain from Focal Ischemic Injury in Rats

  Xinkang Wang, Giora Z. Feuerstein, Lin Xu, Hugh Wang, William A. Schumacher, Martin L. Ogletree, Rebecca Taub, James J.-W. Duan, Carl P. Decicco and Rui-Qin Liu

  Molecular Pharmacology April 2004, 65 (4) 890-896; DOI: https://doi.org/10.1124/mol.65.4.890
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  Glutathione S-Transferase M1 and Multidrug Resistance Protein 1 Act in Synergy to Protect Melanoma Cells from Vincristine Effects

  Philippe Depeille, Pierre Cuq, Sophie Mary, Isabelle Passagne, Alexandre Evrard, Didier Cupissol and Laurence Vian

  Molecular Pharmacology April 2004, 65 (4) 897-905; DOI: https://doi.org/10.1124/mol.65.4.897
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  CCAAT/Enhancer-Binding Protein β (Nuclear Factor for Interleukin 6) Transactivates the Human MDR1 Gene by Interaction with an Inverted CCAAT Box in Human Cancer Cells

  Kevin G. Chen, Sanja Sale, Thomas Tan, Ralph P. Ermoian and Branimir I. Sikic

  Molecular Pharmacology April 2004, 65 (4) 906-916; DOI: https://doi.org/10.1124/mol.65.4.906
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  Atrial Natriuretic Peptide-C Receptor-Induced Attenuation of Adenylyl Cyclase Signaling Activates Phosphatidylinositol Turnover in A10 Vascular Smooth Muscle Cells

  Rima Mouawad, Yuan Li and Madhu B. Anand-Srivastava

  Molecular Pharmacology April 2004, 65 (4) 917-924; DOI: https://doi.org/10.1124/mol.65.4.917
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  Interactions of Nucleoside Analogs, Caffeine, and Nicotine with Human Concentrative Nucleoside Transporters 1 and 2 Stably Produced in a Transport-Defective Human Cell Line

  Thack T. Lang, James D. Young and Carol E. Cass

  Molecular Pharmacology April 2004, 65 (4) 925-933; DOI: https://doi.org/10.1124/mol.65.4.925
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  Aryl Hydrocarbon Receptor Activation and Cytochrome P450 1A Induction by the Mitogen-Activated Protein Kinase Inhibitor U0126 in Hepatocytes

  Lise Andrieux, Sophie Langouët, Alain Fautrel, Fréderic Ezan, Joel A. Krauser, Jean F. Savouret, F. Peter Guengerich, Georges Baffet and André Guillouzo

  Molecular Pharmacology April 2004, 65 (4) 934-943; DOI: https://doi.org/10.1124/mol.65.4.934
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  Analogs of α-Conotoxin MII Are Selective for α6-Containing Nicotinic Acetylcholine Receptors

  J. Michael McIntosh, Layla Azam, Sarah Staheli, Cheryl Dowell, Jon M. Lindstrom, Alexander Kuryatov, James E. Garrett, Michael J. Marks and Paul Whiteaker

  Molecular Pharmacology April 2004, 65 (4) 944-952; DOI: https://doi.org/10.1124/mol.65.4.944
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  Coordinate Regulation of the Human UDP-Glucuronosyltransferase 1A8, 1A9, and 1A10 Genes by Hepatocyte Nuclear Factor 1α and the Caudal-Related Homeodomain Protein 2

  Philip A. Gregory, Rikke H. Lewinsky, Dione A. Gardner-Stephen and Peter I. Mackenzie

  Molecular Pharmacology April 2004, 65 (4) 953-963; DOI: https://doi.org/10.1124/mol.65.4.953
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  Dexamethasone Promotes Toxicity in U937 Cells Exposed to Otherwise Nontoxic Concentrations of Peroxynitrite: Pivotal Role for Lipocortin 1-Mediated Inhibition of Cytosolic Phospholipase A₂

  Ilaria Tommasini and Orazio Cantoni

  Molecular Pharmacology April 2004, 65 (4) 964-972; DOI: https://doi.org/10.1124/mol.65.4.964
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  The Two-Step Model of Prostaglandin Signal Termination: In Vitro Reconstitution with the Prostaglandin Transporter and Prostaglandin 15 Dehydrogenase

  Teruhisa Nomura, Run Lu, Michael L. Pucci and Victor L. Schuster

  Molecular Pharmacology April 2004, 65 (4) 973-978; DOI: https://doi.org/10.1124/mol.65.4.973
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  Functional Regulation of P2X₆ Receptors by N-Linked Glycosylation: Identification of a Novel αβ-Methylene ATP-Sensitive Phenotype

  Clare A. Jones, Catherine Vial, Lynda A. Sellers, Pat P. A. Humphrey, Richard J. Evans and Iain P. Chessell

  Molecular Pharmacology April 2004, 65 (4) 979-985; DOI: https://doi.org/10.1124/mol.65.4.979
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  Temporal Characteristics of cAMP Response Element-Mediated Gene Transcription: Requirement for Sustained cAMP Production

  Jillian G. Baker, Ian P. Hall and Stephen J. Hill

  Molecular Pharmacology April 2004, 65 (4) 986-998; DOI: https://doi.org/10.1124/mol.65.4.986
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  Cultured Rat Microglial Cells Synthesize the Endocannabinoid 2-Arachidonylglycerol, Which Increases Proliferation via a CB₂ Receptor-Dependent Mechanism

  Erica J. Carrier, Christopher S. Kearn, Andrew J. Barkmeier, Nicole M. Breese, Wenqi Yang, Kasem Nithipatikom, Sandra L. Pfister, William B. Campbell and Cecilia J. Hillard

  Molecular Pharmacology April 2004, 65 (4) 999-1007; DOI: https://doi.org/10.1124/mol.65.4.999
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  Characterization of Novel L-threo-β-Benzyloxyaspartate Derivatives, Potent Blockers of the Glutamate Transporters

  Keiko Shimamoto, Ryuichi Sakai, Kiyo Takaoka, Noboru Yumoto, Terumi Nakajima, Susan G. Amara and Yasushi Shigeri

  Molecular Pharmacology April 2004, 65 (4) 1008-1015; DOI: https://doi.org/10.1124/mol.65.4.1008
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  Differential Susceptibilities of Murine Hepatoma 1c1c7 and Tao Cells to the Lysosomal Photosensitizer NPe6: Influence of Aryl Hydrocarbon Receptor on Lysosomal Fragility and Protease Contents

  Joseph A. Caruso, Patricia A. Mathieu, Aby Joiakim, Brendan Leeson, David Kessel, Bonnie F. Sloane and John J. Reiners

  Molecular Pharmacology April 2004, 65 (4) 1016-1028; DOI: https://doi.org/10.1124/mol.65.4.1016
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  Regulation of NAD(P)H:Quinone Oxidoreductase 1 Gene Expression by CYP1A1 Activity

  A. Marchand, R. Barouki and M. Garlatti

  Molecular Pharmacology April 2004, 65 (4) 1029-1037; DOI: https://doi.org/10.1124/mol.65.4.1029
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  Circumvention of Nuclear Factor κB-Induced Chemoresistance by Cytoplasmic-Targeted Anthracyclines

  Jennifer D. Bilyeu, Ganesh R. Panta, Lakita G. Cavin, Christina M. Barrett, Eddie J. Turner, Trevor W. Sweatman, Mervyn Israel, Leonard Lothstein and Marcello Arsura

  Molecular Pharmacology April 2004, 65 (4) 1038-1047; DOI: https://doi.org/10.1124/mol.65.4.1038