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Molecular Pharmacology

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Table of Contents

April 01, 2004; Volume 65,Issue 4

Minireview

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    Computational Lipidomics: A Multiplexed Analysis of Dynamic Changes in Membrane Lipid Composition during Signal Transduction
    Jeffrey S. Forrester, Stephen B. Milne, Pavlina T. Ivanova and H. Alex Brown
    Molecular Pharmacology April 2004, 65 (4) 813-821; DOI: https://doi.org/10.1124/mol.65.4.813

Perspective

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    Scaffolds Direct Src-Specific Signaling in Response to Angiotensin II: New Roles for Cas and GIT1
    Kanchana Natarajan, Guoyong Yin and Bradford C. Berk
    Molecular Pharmacology April 2004, 65 (4) 822-825; DOI: https://doi.org/10.1124/mol.65.4.822

Accelerated Communication

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    An Active and Water-Soluble Truncation Mutant of the Human UDP-Glucuronosyltransferase 1A9
    Mika Kurkela, Saila Mörsky, Jouni Hirvonen, Risto Kostiainen and Moshe Finel
    Molecular Pharmacology April 2004, 65 (4) 826-831; DOI: https://doi.org/10.1124/mol.65.4.826

Articles

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    Src and Cas Are Essentially but Differentially Involved in Angiotensin II-Stimulated Migration of Vascular Smooth Muscle Cells via Extracellular Signal-Regulated Kinase 1/2 and c-Jun NH2-Terminal Kinase Activation
    Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Shoji Kagami, Yuki Izawa, Yoshiko Fujita, Nermin Ali, Yasuhisa Kanematsu, Kazunori Toida, Kazunori Ishimura and Toshiaki Tamaki
    Molecular Pharmacology April 2004, 65 (4) 832-841; DOI: https://doi.org/10.1124/mol.65.4.832
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    Differential Roles of Arg97, Asp293, and Arg108 in Enzyme Stability and Substrate Specificity of CYP2C9
    Leslie J. Dickmann, Charles W. Locuson, Jeffrey P. Jones and Allan E. Rettie
    Molecular Pharmacology April 2004, 65 (4) 842-850; DOI: https://doi.org/10.1124/mol.65.4.842
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    Nitric Oxide (NO) Scavenging and NO Protecting Effects of Quercetin and Their Biological Significance in Vascular Smooth Muscle
    Gustavo López-López, Laura Moreno, Angel Cogolludo, Milagros Galisteo, Manuel Ibarra, Juan Duarte, Federica Lodi, Juan Tamargo and Francisco Perez-Vizcaino
    Molecular Pharmacology April 2004, 65 (4) 851-859; DOI: https://doi.org/10.1124/mol.65.4.851
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    Crystal Structures of the Mitochondrial Deoxyribonucleotidase in Complex with Two Specific Inhibitors
    Agnes Rinaldo-Matthis, Chiara Rampazzo, Jan Balzarini, Peter Reichard, Vera Bianchi and Pär Nordlund
    Molecular Pharmacology April 2004, 65 (4) 860-867; DOI: https://doi.org/10.1124/mol.65.4.860
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    Potent Cyclic Antagonists of the Complement C5a Receptor on Human Polymorphonuclear Leukocytes. Relationships between Structures and Activity
    Darren R. March, Lavinia M. Proctor, Martin J. Stoermer, Robert Sbaglia, Giovanni Abbenante, Robert C. Reid, Trent M. Woodruff, Khemar Wadi, Natalii Paczkowski, Joel D. A. Tyndall, Stephen M. Taylor and David P. Fairlie
    Molecular Pharmacology April 2004, 65 (4) 868-879; DOI: https://doi.org/10.1124/mol.65.4.868
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    Rapamycin Effects Transcriptional Programs in Smooth Muscle Cells Controlling Proliferative and Inflammatory Properties
    Dietlind Zohlnhöfer, Thomas G. Nührenberg, Franz-Josef Neumann, Thomas Richter, Andreas E. May, Roland Schmidt, Katja Denker, Matthias A. Clauss, Albert Schömig and Patrick A. Baeuerle
    Molecular Pharmacology April 2004, 65 (4) 880-889; DOI: https://doi.org/10.1124/mol.65.4.880
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    Inhibition of Tumor Necrosis Factor-α-Converting Enzyme by a Selective Antagonist Protects Brain from Focal Ischemic Injury in Rats
    Xinkang Wang, Giora Z. Feuerstein, Lin Xu, Hugh Wang, William A. Schumacher, Martin L. Ogletree, Rebecca Taub, James J.-W. Duan, Carl P. Decicco and Rui-Qin Liu
    Molecular Pharmacology April 2004, 65 (4) 890-896; DOI: https://doi.org/10.1124/mol.65.4.890
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    Glutathione S-Transferase M1 and Multidrug Resistance Protein 1 Act in Synergy to Protect Melanoma Cells from Vincristine Effects
    Philippe Depeille, Pierre Cuq, Sophie Mary, Isabelle Passagne, Alexandre Evrard, Didier Cupissol and Laurence Vian
    Molecular Pharmacology April 2004, 65 (4) 897-905; DOI: https://doi.org/10.1124/mol.65.4.897
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    CCAAT/Enhancer-Binding Protein β (Nuclear Factor for Interleukin 6) Transactivates the Human MDR1 Gene by Interaction with an Inverted CCAAT Box in Human Cancer Cells
    Kevin G. Chen, Sanja Sale, Thomas Tan, Ralph P. Ermoian and Branimir I. Sikic
    Molecular Pharmacology April 2004, 65 (4) 906-916; DOI: https://doi.org/10.1124/mol.65.4.906
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    Atrial Natriuretic Peptide-C Receptor-Induced Attenuation of Adenylyl Cyclase Signaling Activates Phosphatidylinositol Turnover in A10 Vascular Smooth Muscle Cells
    Rima Mouawad, Yuan Li and Madhu B. Anand-Srivastava
    Molecular Pharmacology April 2004, 65 (4) 917-924; DOI: https://doi.org/10.1124/mol.65.4.917
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    Interactions of Nucleoside Analogs, Caffeine, and Nicotine with Human Concentrative Nucleoside Transporters 1 and 2 Stably Produced in a Transport-Defective Human Cell Line
    Thack T. Lang, James D. Young and Carol E. Cass
    Molecular Pharmacology April 2004, 65 (4) 925-933; DOI: https://doi.org/10.1124/mol.65.4.925
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    Aryl Hydrocarbon Receptor Activation and Cytochrome P450 1A Induction by the Mitogen-Activated Protein Kinase Inhibitor U0126 in Hepatocytes
    Lise Andrieux, Sophie Langouët, Alain Fautrel, Fréderic Ezan, Joel A. Krauser, Jean F. Savouret, F. Peter Guengerich, Georges Baffet and André Guillouzo
    Molecular Pharmacology April 2004, 65 (4) 934-943; DOI: https://doi.org/10.1124/mol.65.4.934
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    Analogs of α-Conotoxin MII Are Selective for α6-Containing Nicotinic Acetylcholine Receptors
    J. Michael McIntosh, Layla Azam, Sarah Staheli, Cheryl Dowell, Jon M. Lindstrom, Alexander Kuryatov, James E. Garrett, Michael J. Marks and Paul Whiteaker
    Molecular Pharmacology April 2004, 65 (4) 944-952; DOI: https://doi.org/10.1124/mol.65.4.944
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    Coordinate Regulation of the Human UDP-Glucuronosyltransferase 1A8, 1A9, and 1A10 Genes by Hepatocyte Nuclear Factor 1α and the Caudal-Related Homeodomain Protein 2
    Philip A. Gregory, Rikke H. Lewinsky, Dione A. Gardner-Stephen and Peter I. Mackenzie
    Molecular Pharmacology April 2004, 65 (4) 953-963; DOI: https://doi.org/10.1124/mol.65.4.953
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    Dexamethasone Promotes Toxicity in U937 Cells Exposed to Otherwise Nontoxic Concentrations of Peroxynitrite: Pivotal Role for Lipocortin 1-Mediated Inhibition of Cytosolic Phospholipase A2
    Ilaria Tommasini and Orazio Cantoni
    Molecular Pharmacology April 2004, 65 (4) 964-972; DOI: https://doi.org/10.1124/mol.65.4.964
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    The Two-Step Model of Prostaglandin Signal Termination: In Vitro Reconstitution with the Prostaglandin Transporter and Prostaglandin 15 Dehydrogenase
    Teruhisa Nomura, Run Lu, Michael L. Pucci and Victor L. Schuster
    Molecular Pharmacology April 2004, 65 (4) 973-978; DOI: https://doi.org/10.1124/mol.65.4.973
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    Functional Regulation of P2X6 Receptors by N-Linked Glycosylation: Identification of a Novel αβ-Methylene ATP-Sensitive Phenotype
    Clare A. Jones, Catherine Vial, Lynda A. Sellers, Pat P. A. Humphrey, Richard J. Evans and Iain P. Chessell
    Molecular Pharmacology April 2004, 65 (4) 979-985; DOI: https://doi.org/10.1124/mol.65.4.979
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    Temporal Characteristics of cAMP Response Element-Mediated Gene Transcription: Requirement for Sustained cAMP Production
    Jillian G. Baker, Ian P. Hall and Stephen J. Hill
    Molecular Pharmacology April 2004, 65 (4) 986-998; DOI: https://doi.org/10.1124/mol.65.4.986
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    Cultured Rat Microglial Cells Synthesize the Endocannabinoid 2-Arachidonylglycerol, Which Increases Proliferation via a CB2 Receptor-Dependent Mechanism
    Erica J. Carrier, Christopher S. Kearn, Andrew J. Barkmeier, Nicole M. Breese, Wenqi Yang, Kasem Nithipatikom, Sandra L. Pfister, William B. Campbell and Cecilia J. Hillard
    Molecular Pharmacology April 2004, 65 (4) 999-1007; DOI: https://doi.org/10.1124/mol.65.4.999
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    Characterization of Novel L-threo-β-Benzyloxyaspartate Derivatives, Potent Blockers of the Glutamate Transporters
    Keiko Shimamoto, Ryuichi Sakai, Kiyo Takaoka, Noboru Yumoto, Terumi Nakajima, Susan G. Amara and Yasushi Shigeri
    Molecular Pharmacology April 2004, 65 (4) 1008-1015; DOI: https://doi.org/10.1124/mol.65.4.1008
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    Differential Susceptibilities of Murine Hepatoma 1c1c7 and Tao Cells to the Lysosomal Photosensitizer NPe6: Influence of Aryl Hydrocarbon Receptor on Lysosomal Fragility and Protease Contents
    Joseph A. Caruso, Patricia A. Mathieu, Aby Joiakim, Brendan Leeson, David Kessel, Bonnie F. Sloane and John J. Reiners
    Molecular Pharmacology April 2004, 65 (4) 1016-1028; DOI: https://doi.org/10.1124/mol.65.4.1016
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    Regulation of NAD(P)H:Quinone Oxidoreductase 1 Gene Expression by CYP1A1 Activity
    A. Marchand, R. Barouki and M. Garlatti
    Molecular Pharmacology April 2004, 65 (4) 1029-1037; DOI: https://doi.org/10.1124/mol.65.4.1029
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    Circumvention of Nuclear Factor κB-Induced Chemoresistance by Cytoplasmic-Targeted Anthracyclines
    Jennifer D. Bilyeu, Ganesh R. Panta, Lakita G. Cavin, Christina M. Barrett, Eddie J. Turner, Trevor W. Sweatman, Mervyn Israel, Leonard Lothstein and Marcello Arsura
    Molecular Pharmacology April 2004, 65 (4) 1038-1047; DOI: https://doi.org/10.1124/mol.65.4.1038

Errata

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    Correction to “8R-Lisuride is a potent stereospecific histamine H1-receptor partial agonist”
    Molecular Pharmacology April 2004, 65 (4) 1048; DOI: https://doi.org/10.1124/mol.65.4.1048
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    Correction to “Up-regulation of brain nicotinic acetylcholine receptors in the rat during long-term self-administration of nicotine: disproportionate increase of the α6 subunit”
    Molecular Pharmacology April 2004, 65 (4) 1049; DOI: https://doi.org/10.1124/mol.65.4.1049
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Molecular Pharmacology: 65 (4)
Molecular Pharmacology
Vol. 65, Issue 4
1 Apr 2004
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