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Molecular Pharmacology

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Table of Contents

July 01, 2004; Volume 66,Issue 1

Minireview

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    G Protein-Coupled Receptor Dimerization: Function and Ligand Pharmacology
    Graeme Milligan
    Molecular Pharmacology July 2004, 66 (1) 1-7; DOI: https://doi.org/10.1124/mol.104.000497

Perspectives

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    Na+/Ca2+ Exchange Inhibitors: Potential Drugs to Mitigate the Severity of Ischemic Injury
    Myles H. Akabas
    Molecular Pharmacology July 2004, 66 (1) 8-10; DOI: https://doi.org/10.1124/mol.104.000232.
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    Cyclic GMP and Phosphodiesterase 5 Inhibitor Therapies: What's on the Horizon?
    Thomas M. Lincoln
    Molecular Pharmacology July 2004, 66 (1) 11-13; DOI: https://doi.org/10.1124/mol.104.001388

Articles

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    The Structural Basis for GTS-21 Selectivity between Human and Rat Nicotinic α7 Receptors
    Clare Stokes, Julia Kay Porter Papke, Nicole A. Horenstein, William R. Kem, Thomas J. McCormack and Roger L. Papke
    Molecular Pharmacology July 2004, 66 (1) 14-24; DOI: https://doi.org/10.1124/mol.66.1.14
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    Modulation of the Cellular Pharmacology of Cisplatin and Its Analogs by the Copper Exporters ATP7A and ATP7B
    Goli Samimi, Kuniyuki Katano, Alison K. Holzer, Roohangiz Safaei and Stephen B. Howell
    Molecular Pharmacology July 2004, 66 (1) 25-32; DOI: https://doi.org/10.1124/mol.66.1.25
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    Mechanisms of Arsenic-Induced Prolongation of Cardiac Repolarization
    Eckhard Ficker, Yuri A. Kuryshev, Adrienne T. Dennis, Carlos Obejero-Paz, Lu Wang, Peter Hawryluk, Barbara A. Wible and Arthur M. Brown
    Molecular Pharmacology July 2004, 66 (1) 33-44; DOI: https://doi.org/10.1124/mol.66.1.33
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    The Exchanger Inhibitory Peptide Region-Dependent Inhibition of Na+/Ca2+ Exchange by SN-6 [2-[4-(4-Nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic Acid Ethyl Ester], a Novel Benzyloxyphenyl Derivative
    Takahiro Iwamoto, Yutaka Inoue, Kazuhiko Ito, Takahiro Sakaue, Satomi Kita and Takeshi Katsuragi
    Molecular Pharmacology July 2004, 66 (1) 45-55; DOI: https://doi.org/10.1124/mol.66.1.45
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    Insight into the Mechanism of Action of Neuroactive Steroids
    Kendall D. W. Morris and Jahanshah Amin
    Molecular Pharmacology July 2004, 66 (1) 56-69; DOI: https://doi.org/10.1124/mol.66.1.56
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    In Silico Simulation of Inhibitor Drug Effects on Nuclear Factor-κB Pathway Dynamics
    Myong-Hee Sung and Richard Simon
    Molecular Pharmacology July 2004, 66 (1) 70-75; DOI: https://doi.org/10.1124/mol.66.1.70
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    PKCδ Associates with and Is Involved in the Phosphorylation of RasGRP3 in Response to Phorbol Esters
    Chaya Brodie, Rivka Steinhart, Gila Kazimirsky, Hadara Rubinfeld, Tehila Hyman, Jolene N. Ayres, Gang Min Hur, Attila Toth, Dazhi Yang, Susan H. Garfield, James C. Stone and Peter M. Blumberg
    Molecular Pharmacology July 2004, 66 (1) 76-84; DOI: https://doi.org/10.1124/mol.66.1.76
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    Nicotinic Acetylcholine Receptor Subtypes Expression during Rat Retina Development and Their Regulation by Visual Experience
    Milena Moretti, Silvia Vailati, Michele Zoli, Giordano Lippi, Loredana Riganti, Renato Longhi, Alessandro Viegi, Francesco Clementi and Cecilia Gotti
    Molecular Pharmacology July 2004, 66 (1) 85-96; DOI: https://doi.org/10.1124/mol.66.1.85
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    Functional Selectivity of D2 Receptor Ligands in a Chinese Hamster Ovary hD2L Cell Line: Evidence for Induction of Ligand-Specific Receptor States
    Elaine A. Gay, Jonathan D. Urban, David E. Nichols, Gerry S. Oxford and Richard B. Mailman
    Molecular Pharmacology July 2004, 66 (1) 97-105; DOI: https://doi.org/10.1124/mol.66.1.97
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    Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery
    L. M. Bohn, L. A. Dykstra, R. J. Lefkowitz, M. G. Caron and L. S. Barak
    Molecular Pharmacology July 2004, 66 (1) 106-112; DOI: https://doi.org/10.1124/mol.66.1.106
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    Laulimalide and Paclitaxel: A Comparison of Their Effects on Tubulin Assembly and Their Synergistic Action When Present Simultaneously
    Eric J. Gapud, Ruoli Bai, Arun K. Ghosh and Ernest Hamel
    Molecular Pharmacology July 2004, 66 (1) 113-121; DOI: https://doi.org/10.1124/mol.66.1.113
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    Roles of Heme Oxygenase-1 in the Antiproliferative and Antiapoptotic Effects of Nitric Oxide on Jurkat T Cells
    Hyun-Ock Pae, Byung-Min Choi, Gi-Su Oh, Myeong-Su Lee, Do-Gon Ryu, Hyun-Yul Rhew, Yung-Myung Kim and Hun-Taeg Chung
    Molecular Pharmacology July 2004, 66 (1) 122-128; DOI: https://doi.org/10.1124/mol.66.1.122
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    Use of 2-Azido-3-[125I]iodo-7,8-dibromodibenzo-p-dioxin as a Probe to Determine the Relative Ligand Affinity of Human versus Mouse Aryl Hydrocarbon Receptor in Cultured Cells
    Preeti Ramadoss and Gary H. Perdew
    Molecular Pharmacology July 2004, 66 (1) 129-136; DOI: https://doi.org/10.1124/mol.66.1.129
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    Intracellular Ca2+ Regulates Amphetamine-Induced Dopamine Efflux and Currents Mediated by the Human Dopamine Transporter
    Margaret E. Gnegy, Habibeh Khoshbouei, Kelly A. Berg, Jonathan A. Javitch, William P. Clarke, Minjia Zhang and Aurelio Galli
    Molecular Pharmacology July 2004, 66 (1) 137-143; DOI: https://doi.org/10.1124/mol.66.1.137
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    Binding of Tritiated Sildenafil, Tadalafil, or Vardenafil to the Phosphodiesterase-5 Catalytic Site Displays Potency, Specificity, Heterogeneity, and cGMP Stimulation
    Mitsi A. Blount, Alfreda Beasley, Roya Zoraghi, Konjeti R. Sekhar, Emmanuel P. Bessay, Sharron H. Francis and Jackie D. Corbin
    Molecular Pharmacology July 2004, 66 (1) 144-152; DOI: https://doi.org/10.1124/mol.66.1.144
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    Enhanced 7-Ethyl-10-hydroxycamptothecin (SN-38) Lethality by Methylselenocysteine Is Associated with Chk2 Phosphorylation at Threonine-68 and Down-Regulation of Cdc6 Expression
    Ming-Biao Yin, Zhan-Rong Li, Shousong Cao, Farukh A. Durrani, Rami G. Azrak, Cheryl Frank and Youcef M. Rustum
    Molecular Pharmacology July 2004, 66 (1) 153-160; DOI: https://doi.org/10.1124/mol.66.1.153
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    Dipole Potential and Head-Group Spacing Are Determinants for the Membrane Partitioning of Pregnanolone
    Juha-Matti I. Alakoskela, Tim Söderlund, Juha M. Holopainen and Paavo K. J. Kinnunen
    Molecular Pharmacology July 2004, 66 (1) 161-168; DOI: https://doi.org/10.1124/mol.104.000075
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    A Single Point Mutation Confers Properties of the Muscle-Type Nicotinic Acetylcholine Receptor to Homomeric α7 Receptors
    Andon N. Placzek, Francesca Grassi, Thaddeus Papke, Edwin M. Meyer and Roger L. Papke
    Molecular Pharmacology July 2004, 66 (1) 169-177; DOI: https://doi.org/10.1124/mol.66.1.169
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    9-β-d-Arabinofuranosyl-2-fluoroadenine Inhibits Expression of Vascular Endothelial Growth Factor through Hypoxia-Inducible Factor-1 in Human Ovarian Cancer Cells
    Jing Fang, Zongxian Cao, Yi Charlie Chen, Eddie Reed and Bing-Hua Jiang
    Molecular Pharmacology July 2004, 66 (1) 178-186; DOI: https://doi.org/10.1124/mol.66.1.178
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    Activation of Phosphoinositide 3-kinase in Response to High Glucose Leads to Regulation of Reactive Oxygen Species-Related Nuclear Factor-κB Activation and Cyclooxygenase-2 Expression in Mesangial Cells
    Meei Ling Sheu, Feng Ming Ho, Kuo Fang Chao, Ming Liang Kuo and Shing Hwa Liu
    Molecular Pharmacology July 2004, 66 (1) 187-196; DOI: https://doi.org/10.1124/mol.66.1.187

Errata

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    Correction to “Characterization of human α4β2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cells”
    Molecular Pharmacology July 2004, 66 (1) 197; DOI: https://doi.org/10.1124/mol.66.1.197
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    Correction to “Probing receptor structure/function with chimeric G-protein-coupled receptors”
    Molecular Pharmacology July 2004, 66 (1) 198; DOI: https://doi.org/10.1124/mol.66.1.198
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Molecular Pharmacology: 66 (1)
Molecular Pharmacology
Vol. 66, Issue 1
1 Jul 2004
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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