Molecular Pharmacology: 66 (1)

July 01, 2004; Volume 66,Issue 1

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G Protein-Coupled Receptor Dimerization: Function and Ligand Pharmacology
Graeme Milligan

Molecular Pharmacology July 2004, 66 (1) 1-7; DOI: https://doi.org/10.1124/mol.104.000497

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Na⁺/Ca²⁺ Exchange Inhibitors: Potential Drugs to Mitigate the Severity of Ischemic Injury
Myles H. Akabas

Molecular Pharmacology July 2004, 66 (1) 8-10; DOI: https://doi.org/10.1124/mol.104.000232.
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Cyclic GMP and Phosphodiesterase 5 Inhibitor Therapies: What's on the Horizon?
Thomas M. Lincoln

Molecular Pharmacology July 2004, 66 (1) 11-13; DOI: https://doi.org/10.1124/mol.104.001388

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The Structural Basis for GTS-21 Selectivity between Human and Rat Nicotinic α7 Receptors
Clare Stokes, Julia Kay Porter Papke, Nicole A. Horenstein, William R. Kem, Thomas J. McCormack and Roger L. Papke

Molecular Pharmacology July 2004, 66 (1) 14-24; DOI: https://doi.org/10.1124/mol.66.1.14
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Modulation of the Cellular Pharmacology of Cisplatin and Its Analogs by the Copper Exporters ATP7A and ATP7B
Goli Samimi, Kuniyuki Katano, Alison K. Holzer, Roohangiz Safaei and Stephen B. Howell

Molecular Pharmacology July 2004, 66 (1) 25-32; DOI: https://doi.org/10.1124/mol.66.1.25
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Mechanisms of Arsenic-Induced Prolongation of Cardiac Repolarization
Eckhard Ficker, Yuri A. Kuryshev, Adrienne T. Dennis, Carlos Obejero-Paz, Lu Wang, Peter Hawryluk, Barbara A. Wible and Arthur M. Brown

Molecular Pharmacology July 2004, 66 (1) 33-44; DOI: https://doi.org/10.1124/mol.66.1.33
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The Exchanger Inhibitory Peptide Region-Dependent Inhibition of Na⁺/Ca²⁺ Exchange by SN-6 [2-[4-(4-Nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic Acid Ethyl Ester], a Novel Benzyloxyphenyl Derivative
Takahiro Iwamoto, Yutaka Inoue, Kazuhiko Ito, Takahiro Sakaue, Satomi Kita and Takeshi Katsuragi

Molecular Pharmacology July 2004, 66 (1) 45-55; DOI: https://doi.org/10.1124/mol.66.1.45
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Insight into the Mechanism of Action of Neuroactive Steroids
Kendall D. W. Morris and Jahanshah Amin

Molecular Pharmacology July 2004, 66 (1) 56-69; DOI: https://doi.org/10.1124/mol.66.1.56
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In Silico Simulation of Inhibitor Drug Effects on Nuclear Factor-κB Pathway Dynamics
Myong-Hee Sung and Richard Simon

Molecular Pharmacology July 2004, 66 (1) 70-75; DOI: https://doi.org/10.1124/mol.66.1.70
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PKCδ Associates with and Is Involved in the Phosphorylation of RasGRP3 in Response to Phorbol Esters
Chaya Brodie, Rivka Steinhart, Gila Kazimirsky, Hadara Rubinfeld, Tehila Hyman, Jolene N. Ayres, Gang Min Hur, Attila Toth, Dazhi Yang, Susan H. Garfield, James C. Stone and Peter M. Blumberg

Molecular Pharmacology July 2004, 66 (1) 76-84; DOI: https://doi.org/10.1124/mol.66.1.76
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Nicotinic Acetylcholine Receptor Subtypes Expression during Rat Retina Development and Their Regulation by Visual Experience
Milena Moretti, Silvia Vailati, Michele Zoli, Giordano Lippi, Loredana Riganti, Renato Longhi, Alessandro Viegi, Francesco Clementi and Cecilia Gotti

Molecular Pharmacology July 2004, 66 (1) 85-96; DOI: https://doi.org/10.1124/mol.66.1.85
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Functional Selectivity of D₂ Receptor Ligands in a Chinese Hamster Ovary hD_2L Cell Line: Evidence for Induction of Ligand-Specific Receptor States
Elaine A. Gay, Jonathan D. Urban, David E. Nichols, Gerry S. Oxford and Richard B. Mailman

Molecular Pharmacology July 2004, 66 (1) 97-105; DOI: https://doi.org/10.1124/mol.66.1.97
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Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery
L. M. Bohn, L. A. Dykstra, R. J. Lefkowitz, M. G. Caron and L. S. Barak

Molecular Pharmacology July 2004, 66 (1) 106-112; DOI: https://doi.org/10.1124/mol.66.1.106
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Laulimalide and Paclitaxel: A Comparison of Their Effects on Tubulin Assembly and Their Synergistic Action When Present Simultaneously
Eric J. Gapud, Ruoli Bai, Arun K. Ghosh and Ernest Hamel

Molecular Pharmacology July 2004, 66 (1) 113-121; DOI: https://doi.org/10.1124/mol.66.1.113
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Roles of Heme Oxygenase-1 in the Antiproliferative and Antiapoptotic Effects of Nitric Oxide on Jurkat T Cells
Hyun-Ock Pae, Byung-Min Choi, Gi-Su Oh, Myeong-Su Lee, Do-Gon Ryu, Hyun-Yul Rhew, Yung-Myung Kim and Hun-Taeg Chung

Molecular Pharmacology July 2004, 66 (1) 122-128; DOI: https://doi.org/10.1124/mol.66.1.122
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Use of 2-Azido-3-[¹²⁵I]iodo-7,8-dibromodibenzo-p-dioxin as a Probe to Determine the Relative Ligand Affinity of Human versus Mouse Aryl Hydrocarbon Receptor in Cultured Cells
Preeti Ramadoss and Gary H. Perdew

Molecular Pharmacology July 2004, 66 (1) 129-136; DOI: https://doi.org/10.1124/mol.66.1.129
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Intracellular Ca²⁺ Regulates Amphetamine-Induced Dopamine Efflux and Currents Mediated by the Human Dopamine Transporter
Margaret E. Gnegy, Habibeh Khoshbouei, Kelly A. Berg, Jonathan A. Javitch, William P. Clarke, Minjia Zhang and Aurelio Galli

Molecular Pharmacology July 2004, 66 (1) 137-143; DOI: https://doi.org/10.1124/mol.66.1.137
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Binding of Tritiated Sildenafil, Tadalafil, or Vardenafil to the Phosphodiesterase-5 Catalytic Site Displays Potency, Specificity, Heterogeneity, and cGMP Stimulation
Mitsi A. Blount, Alfreda Beasley, Roya Zoraghi, Konjeti R. Sekhar, Emmanuel P. Bessay, Sharron H. Francis and Jackie D. Corbin

Molecular Pharmacology July 2004, 66 (1) 144-152; DOI: https://doi.org/10.1124/mol.66.1.144
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Enhanced 7-Ethyl-10-hydroxycamptothecin (SN-38) Lethality by Methylselenocysteine Is Associated with Chk2 Phosphorylation at Threonine-68 and Down-Regulation of Cdc6 Expression
Ming-Biao Yin, Zhan-Rong Li, Shousong Cao, Farukh A. Durrani, Rami G. Azrak, Cheryl Frank and Youcef M. Rustum

Molecular Pharmacology July 2004, 66 (1) 153-160; DOI: https://doi.org/10.1124/mol.66.1.153
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Dipole Potential and Head-Group Spacing Are Determinants for the Membrane Partitioning of Pregnanolone
Juha-Matti I. Alakoskela, Tim Söderlund, Juha M. Holopainen and Paavo K. J. Kinnunen

Molecular Pharmacology July 2004, 66 (1) 161-168; DOI: https://doi.org/10.1124/mol.104.000075
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A Single Point Mutation Confers Properties of the Muscle-Type Nicotinic Acetylcholine Receptor to Homomeric α7 Receptors
Andon N. Placzek, Francesca Grassi, Thaddeus Papke, Edwin M. Meyer and Roger L. Papke

Molecular Pharmacology July 2004, 66 (1) 169-177; DOI: https://doi.org/10.1124/mol.66.1.169
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9-β-d-Arabinofuranosyl-2-fluoroadenine Inhibits Expression of Vascular Endothelial Growth Factor through Hypoxia-Inducible Factor-1 in Human Ovarian Cancer Cells
Jing Fang, Zongxian Cao, Yi Charlie Chen, Eddie Reed and Bing-Hua Jiang

Molecular Pharmacology July 2004, 66 (1) 178-186; DOI: https://doi.org/10.1124/mol.66.1.178
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Activation of Phosphoinositide 3-kinase in Response to High Glucose Leads to Regulation of Reactive Oxygen Species-Related Nuclear Factor-κB Activation and Cyclooxygenase-2 Expression in Mesangial Cells
Meei Ling Sheu, Feng Ming Ho, Kuo Fang Chao, Ming Liang Kuo and Shing Hwa Liu

Molecular Pharmacology July 2004, 66 (1) 187-196; DOI: https://doi.org/10.1124/mol.66.1.187

Errata

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Correction to “Characterization of human α4β2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cells”
Molecular Pharmacology July 2004, 66 (1) 197; DOI: https://doi.org/10.1124/mol.66.1.197
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Correction to “Probing receptor structure/function with chimeric G-protein-coupled receptors”
Molecular Pharmacology July 2004, 66 (1) 198; DOI: https://doi.org/10.1124/mol.66.1.198

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