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Unexpected Mexiletine Responses of a Mutant Cardiac Na+ Channel Implicate the Selectivity Filter as a Structural Determinant of Antiarrhythmic Drug Access

Koji Sasaki, Naomasa Makita, Akihiko Sunami, Harumizu Sakurada, Nobumasa Shirai, Hisataka Yokoi, Akinori Kimura, Noritsugu Tohse, Masayasu Hiraoka and Akira Kitabatake
Molecular Pharmacology August 2004, 66 (2) 330-336; DOI: https://doi.org/10.1124/mol.66.2.330
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Research ArticleArticle

Unexpected Mexiletine Responses of a Mutant Cardiac Na+ Channel Implicate the Selectivity Filter as a Structural Determinant of Antiarrhythmic Drug Access

Koji Sasaki, Naomasa Makita, Akihiko Sunami, Harumizu Sakurada, Nobumasa Shirai, Hisataka Yokoi, Akinori Kimura, Noritsugu Tohse, Masayasu Hiraoka and Akira Kitabatake
Molecular Pharmacology August 1, 2004, 66 (2) 330-336; DOI: https://doi.org/10.1124/mol.66.2.330
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