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Research ArticleArticle

Glutathione Depletion in CYP2E1-Expressing Liver Cells Induces Toxicity Due to the Activation of p38 Mitogen-Activated Protein Kinase and Reduction of Nuclear Factor-κB DNA Binding Activity

Defeng Wu and Arthur Cederbaum
Molecular Pharmacology September 2004, 66 (3) 749-760; DOI: https://doi.org/10.1124/mol.104.002048

Article Information

vol. 66 no. 3 749-760
DOI 
https://doi.org/10.1124/mol.104.002048
PubMed 
15322268
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received April 27, 2004
  • Accepted June 11, 2004
  • Published online August 20, 2004.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Defeng Wu and
  2. Arthur Cederbaum
  1. Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, New York
  1. Address correspondence to:
    Dr. Arthur I. Cederbaum, Department of Pharmacology and Biological Chemistry, Box 1603, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029. E-mail: arthur.cederbaum{at}mssm.edu
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Research ArticleArticle

Glutathione Depletion in CYP2E1-Expressing Liver Cells Induces Toxicity Due to the Activation of p38 Mitogen-Activated Protein Kinase and Reduction of Nuclear Factor-κB DNA Binding Activity

Defeng Wu and Arthur Cederbaum
Molecular Pharmacology September 1, 2004, 66 (3) 749-760; DOI: https://doi.org/10.1124/mol.104.002048
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